标题
Vascular Remodelling and Mesenchymal Transition in Systemic Sclerosis
作者
关键词
-
出版物
Stem Cells International
Volume 2016, Issue -, Pages 1-12
出版商
Hindawi Limited
发表日期
2016-03-17
DOI
10.1155/2016/4636859
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- HMGB1 induced endothelial permeability promotes myocardial fibrosis in diabetic cardiomyopathy
- (2017) Zhaowei Zhu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality?
- (2016) Sergio A. Jimenez et al. MATRIX BIOLOGY
- Netrin-1 regulates fibrocyte accumulation in the decellularized fibrotic scleroderma lung microenvironment and in bleomycin induced pulmonary fibrosis
- (2016) Huanxing Sun et al. Arthritis & Rheumatology
- Ambrisentan and Tadalafil Up-front Combination Therapy in Scleroderma-associated Pulmonary Arterial Hypertension
- (2015) Paul M. Hassoun et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Decreased expression of neuropilin-1 as a novel key factor contributing to peripheral microvasculopathy and defective angiogenesis in systemic sclerosis
- (2015) Eloisa Romano et al. ANNALS OF THE RHEUMATIC DISEASES
- Cross-sectional study of soluble selectins, fractions of circulating microparticles and their relationship to lung and skin involvement in systemic sclerosis
- (2015) Line V. Iversen et al. BMC MUSCULOSKELETAL DISORDERS
- Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress
- (2015) Jan-Renier A.J. Moonen et al. CARDIOVASCULAR RESEARCH
- MiR-125b is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis
- (2015) Varun Nagpal et al. CIRCULATION
- Scleroderma renal crisis
- (2015) Marie Hudson CURRENT OPINION IN RHEUMATOLOGY
- Update on macrophages and innate immunity in scleroderma
- (2015) Jennifer J. Chia et al. CURRENT OPINION IN RHEUMATOLOGY
- 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
- (2015) Nazzareno Galiè et al. EUROPEAN RESPIRATORY JOURNAL
- Platelet-derived HMGB1 is a critical mediator of thrombosis
- (2015) Sebastian Vogel et al. JOURNAL OF CLINICAL INVESTIGATION
- The Endothelial-mesenchymal Transition in Systemic Sclerosis Is Induced by Endothelin-1 and Transforming Growth Factor- and May Be Blocked by Macitentan, a Dual Endothelin-1 Receptor Antagonist
- (2015) P. Cipriani et al. JOURNAL OF RHEUMATOLOGY
- Unknown
- (2015) Huan Yang et al. MOLECULAR MEDICINE
- Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension
- (2015) Nazzareno Galiè et al. NEW ENGLAND JOURNAL OF MEDICINE
- Partially Evoked Epithelial-Mesenchymal Transition (EMT) Is Associated with Increased TGFβ Signaling within Lesional Scleroderma Skin
- (2015) Joanna Nikitorowicz-Buniak et al. PLoS One
- The Role of MicroRNAs in Autoimmune Diseases with Skin Involvement
- (2015) X. Deng et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi
- (2015) Michael Bode et al. THROMBOSIS AND HAEMOSTASIS
- Endothelial-to-mesenchymal transition induced by Wnt 3a in keloid pathogenesis
- (2015) Won Jai Lee et al. WOUND REPAIR AND REGENERATION
- Plexin-D1/Semaphorin 3E pathway may contribute to dysregulation of vascular tone control and defective angiogenesis in systemic sclerosis
- (2015) Celestina Mazzotta et al. ARTHRITIS RESEARCH & THERAPY
- Parietal and intravascular innate mechanisms of vascular inflammation
- (2015) Giuseppe A Ramirez et al. ARTHRITIS RESEARCH & THERAPY
- Chop deficiency prevents UUO-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1/TLR4/NFκB/IL-1β signaling
- (2015) M Zhang et al. Cell Death & Disease
- Macrophage Involvement in Systemic Sclerosis: Do We Need More Evidence?
- (2015) Giuseppina Stifano et al. Current Rheumatology Reports
- Emerging Roles of Innate Immune Signaling and Toll-Like Receptors in Fibrosis and Systemic Sclerosis
- (2015) Swati Bhattacharyya et al. Current Rheumatology Reports
- Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease
- (2015) Fabian A. Mendoza et al. Arthritis & Rheumatology
- Fibrosis, Vascular Activation, and Immune Abnormalities Resembling Systemic Sclerosis in Bleomycin-Treated Fli-1-Haploinsufficient Mice
- (2015) Takashi Taniguchi et al. Arthritis & Rheumatology
- A Reactive Oxygen Species-Mediated Loop Maintains Increased Expression of NADPH Oxidases 2 and 4 in Skin Fibroblasts From Patients With Systemic Sclerosis
- (2015) Tatiana Spadoni et al. Arthritis & Rheumatology
- Fibrogenic Cell Plasticity Blunts Tissue Regeneration and Aggravates Muscular Dystrophy
- (2015) Patrizia Pessina et al. Stem Cell Reports
- Bosentan in Pulmonary Hypertension Associated with Fibrotic Idiopathic Interstitial Pneumonia
- (2014) Tamera J. Corte et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Wnt CoreceptorLrp5Is a Driver of Idiopathic Pulmonary Fibrosis
- (2014) Anna P. Lam et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytesin vitro
- (2014) Donal O'Kane et al. EXPERIMENTAL DERMATOLOGY
- Emerging role of HMGB1 in fibrotic diseases
- (2014) Liu-Cheng Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Leukocyte HMGB1 Is Required for Vessel Remodeling in Regenerating Muscles
- (2014) L. Campana et al. JOURNAL OF IMMUNOLOGY
- Altered MCM Protein Levels and Autophagic Flux in Aged and Systemic Sclerosis Dermal Fibroblasts
- (2014) Verónica I. Dumit et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Molecular and cellular basis of scleroderma
- (2014) Beate Eckes et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Procalcitonin in Takayasu Arteritis
- (2014) E. TOMBETTI et al. JOURNAL OF RHEUMATOLOGY
- Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps
- (2014) N. Maugeri et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-β1 and TGF-β2-dependent pathway
- (2014) Ignacio Montorfano et al. LABORATORY INVESTIGATION
- Transforming growth factor β—at the centre of systemic sclerosis
- (2014) Robert Lafyatis Nature Reviews Rheumatology
- Giant-Cell Arteritis and Polymyalgia Rheumatica
- (2014) Cornelia M. Weyand et al. NEW ENGLAND JOURNAL OF MEDICINE
- How macrophages ring the inflammation alarm
- (2014) M. E. Bianchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetics, the holy grail in the pathogenesis of systemic sclerosis
- (2014) Nezam Altorok et al. RHEUMATOLOGY
- Systemic pentraxin-3 levels reflect vascular enhancement and progression in Takayasu arteritis
- (2014) Enrico Tombetti et al. ARTHRITIS RESEARCH & THERAPY
- Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis
- (2014) Giuseppina Stifano et al. ARTHRITIS RESEARCH & THERAPY
- Role of Cellular Senescence and NOX4-Mediated Oxidative Stress in Systemic Sclerosis Pathogenesis
- (2014) Sonsoles Piera-Velazquez et al. Current Rheumatology Reports
- WNT/β-Catenin Signaling Induces IL-1β Expression by Alveolar Epithelial Cells in Pulmonary Fibrosis
- (2013) Verena Aumiller et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin
- (2013) Allison L Mathes et al. ANNALS OF THE RHEUMATIC DISEASES
- The Translocation of Nuclear Molecules During Inflammation and Cell Death
- (2013) David S. Pisetsky ANTIOXIDANTS & REDOX SIGNALING
- Inflammation, DAMPs, Tumor Development, and Progression: A Vicious Circle Orchestrated by Redox Signaling
- (2013) Patrizia Castellani et al. ANTIOXIDANTS & REDOX SIGNALING
- Oxidative Stress Elicits Platelet/Leukocyte Inflammatory Interactions via HMGB1: A Candidate for Microvessel Injury in Sytemic Sclerosis
- (2013) Norma Maugeri et al. ANTIOXIDANTS & REDOX SIGNALING
- Review: Evidence That Systemic Sclerosis Is a Vascular Disease
- (2013) Marco Matucci-Cerinic et al. ARTHRITIS AND RHEUMATISM
- Increased Expression of Endoplasmic Reticulum Stress and Unfolded Protein Response Genes in Peripheral Blood Mononuclear Cells From Patients With Limited Cutaneous Systemic Sclerosis and Pulmonary Arterial Hypertension
- (2013) Stefania Lenna et al. ARTHRITIS AND RHEUMATISM
- Intravascular immunity as a key to systemic vasculitis: a work in progress, gaining momentum
- (2013) G. A. Ramirez et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease
- (2013) Jianhua He et al. Clinical and Experimental Nephrology
- Interferon-γ promotes vascular remodeling in human microvascular endothelial cells by upregulating endothelin (ET)-1 and transforming growth factor (TGF) β2
- (2013) Izabela Chrobak et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease
- (2013) Rafael Kramann et al. JOURNAL OF PATHOLOGY
- Treatment of Refractory Takayasu Arteritis with Tocilizumab: 7 Italian Patients from a Single Referral Center
- (2013) E. Tombetti et al. JOURNAL OF RHEUMATOLOGY
- Right Heart Adaptation to Pulmonary Arterial Hypertension
- (2013) Anton Vonk-Noordegraaf et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Proteome-wide Analysis and CXCL4 as a Biomarker in Systemic Sclerosis
- (2013) Lenny van Bon et al. NEW ENGLAND JOURNAL OF MEDICINE
- State of the art on nailfold capillaroscopy: a reliable diagnostic tool and putative biomarker in rheumatology?
- (2013) M. Cutolo et al. RHEUMATOLOGY
- Modern Age Pathology of Pulmonary Arterial Hypertension
- (2012) Elvira Stacher et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis
- (2012) Christian Beyer et al. ANNALS OF THE RHEUMATIC DISEASES
- Host Responses in Tissue Repair and Fibrosis
- (2012) Jeremy S. Duffield et al. Annual Review of Pathology-Mechanisms of Disease
- Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells
- (2012) Jun Wei et al. ARTHRITIS AND RHEUMATISM
- Circulating platelets as a source of the damage-associated molecular pattern HMGB1 in patients with systemic sclerosis
- (2012) Norma Maugeri et al. AUTOIMMUNITY
- Molecular basis of cardiac endothelial-to-mesenchymal transition (EndMT): Differential expression of microRNAs during EndMT
- (2012) Asish K. Ghosh et al. CELLULAR SIGNALLING
- HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4
- (2012) Milena Schiraldi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
- (2012) Emilie Venereau et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The role of circulating fibrocytes in inflammation and autoimmunity
- (2012) Carole L. Galligan et al. JOURNAL OF LEUKOCYTE BIOLOGY
- HMGB1 and leukocyte migration during trauma and sterile inflammation
- (2012) Emilie Venereau et al. MOLECULAR IMMUNOLOGY
- Unknown
- (2012) Huan Yang et al. MOLECULAR MEDICINE
- HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease
- (2012) Helena Erlandsson Harris et al. Nature Reviews Rheumatology
- The pathogenesis, diagnosis and treatment of Raynaud phenomenon
- (2012) Ariane L. Herrick Nature Reviews Rheumatology
- The contribution of platelets to the pathogenesis of Raynaud's phenomenon and systemic sclerosis
- (2012) J. D. Pauling et al. PLATELETS
- Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery
- (2012) K. Hayakawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microparticles as mediators and biomarkers of rheumatic disease
- (2012) D. S. Pisetsky et al. RHEUMATOLOGY
- Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
- (2012) Alfiya Akhmetshina et al. Nature Communications
- Morphogen Pathways in Systemic Sclerosis
- (2012) Christian Beyer et al. Current Rheumatology Reports
- Is There Evidence for Vasculitis in Systemic Sclerosis?
- (2012) Lesley Ann Saketkoo et al. Current Rheumatology Reports
- The role of platelets in the pathogenesis of systemic sclerosis
- (2012) Giuseppe A. Ramirez et al. Frontiers in Immunology
- Inflammation-Induced Endothelial-to-Mesenchymal Transition
- (2011) Florian Rieder et al. AMERICAN JOURNAL OF PATHOLOGY
- Increased Accumulation of Extracellular Thrombospondin-2 Due to Low Degradation Activity Stimulates Type I Collagen Expression in Scleroderma Fibroblasts
- (2011) Ikko Kajihara et al. AMERICAN JOURNAL OF PATHOLOGY
- HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection
- (2011) Ulf Andersson et al. Annual Review of Immunology
- HMGB1 and Microparticles as Mediators of the Immune Response to Cell Death
- (2011) David S. Pisetsky et al. ANTIOXIDANTS & REDOX SIGNALING
- High-Mobility Group Box 1 Release and Redox Regulation Accompany Regeneration and Remodeling of Skeletal Muscle
- (2011) Michela Vezzoli et al. ANTIOXIDANTS & REDOX SIGNALING
- Transforming Growth Factor-β–Induced Endothelial-to-Mesenchymal Transition Is Partly Mediated by MicroRNA-21
- (2011) Regalla Kumarswamy et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Induction of apoptosis in circulating angiogenic cells by microparticles
- (2011) Jörg H. W. Distler et al. ARTHRITIS AND RHEUMATISM
- Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitro
- (2011) Zhaodong Li et al. ARTHRITIS AND RHEUMATISM
- Overexpression of VEGF 165 b, an Inhibitory Splice Variant of Vascular Endothelial Growth Factor, Leads to Insufficient Angiogenesis in Patients With Systemic Sclerosis
- (2011) Mirko Manetti et al. CIRCULATION RESEARCH
- Early detection of pulmonary vascular disease in pulmonary arterial hypertension: time to move forward
- (2011) E. M. T. Lau et al. EUROPEAN HEART JOURNAL
- Platelet-derived serotonin links vascular disease and tissue fibrosis
- (2011) Clara Dees et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Leukocyte integrin activation and deactivation: novel mechanisms of balancing inflammation
- (2011) Alexander Zarbock et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Plasma Platelet-derived Microparticles in Patients with Connective Tissue Diseases
- (2011) C. OYABU et al. JOURNAL OF RHEUMATOLOGY
- Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities
- (2011) Swati Bhattacharyya et al. Nature Reviews Rheumatology
- Redox remodeling: a candidate regulator of HMGB1 function in injured skeletal muscle
- (2010) Michela Vezzoli et al. Annals of the New York Academy of Sciences
- Endothelial activation and apoptosis mediated by neutrophil-dependent interleukin 6 trans-signalling: a novel target for systemic sclerosis?
- (2010) T. C. Barnes et al. ANNALS OF THE RHEUMATIC DISEASES
- dsRNA activation of endothelin-1 and markers of vascular activation in endothelial cells and fibroblasts
- (2010) G. Farina et al. ANNALS OF THE RHEUMATIC DISEASES
- High-Mobility Group Box 1, Oxidative Stress, and Disease
- (2010) Daolin Tang et al. ANTIOXIDANTS & REDOX SIGNALING
- High-mobility group box 1 (HMGB1) as a master regulator of innate immunity
- (2010) Alessandra Castiglioni et al. CELL AND TISSUE RESEARCH
- Antagonistic Effect of the Matricellular Signaling Protein CCN3 on TGF-β- and Wnt-Mediated Fibrillinogenesis in Systemic Sclerosis and Marfan Syndrome
- (2010) Raphael Lemaire et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype
- (2010) Susan K Mathai et al. LABORATORY INVESTIGATION
- Takayasu arteritis—advances in diagnosis and management
- (2010) Justin C. Mason Nature Reviews Rheumatology
- Cellular and molecular aspects of vascular dysfunction in systemic sclerosis
- (2010) Maria Trojanowska Nature Reviews Rheumatology
- Pulmonary Hypertension in Systemic Sclerosis
- (2010) Soumya Chatterjee SEMINARS IN ARTHRITIS AND RHEUMATISM
- Heart involvement in systemic sclerosis: Evolving concept and diagnostic methodologies
- (2009) Christophe Meune et al. Archives of Cardiovascular Diseases
- Differential Regulation of Transforming Growth Factor β Signaling Pathways by Notch in Human Endothelial Cells
- (2009) YangXin Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells
- (2009) Lara Campana et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Scleroderma
- (2009) Armando Gabrielli et al. NEW ENGLAND JOURNAL OF MEDICINE
- The transport of high amounts of vascular endothelial growth factor by blood platelets underlines their potential contribution in systemic sclerosis angiogenesis
- (2009) A. Solanilla et al. RHEUMATOLOGY
- IMMUNOLOGY: Dangers In and Out
- (2009) M. E. Bianchi et al. SCIENCE
- Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis
- (2009) Christian Beyer et al. ARTHRITIS RESEARCH & THERAPY
- The relationship between plasma microparticles and disease manifestations in patients with systemic sclerosis
- (2008) Serena Guiducci et al. ARTHRITIS AND RHEUMATISM
- Vascular Disease in Scleroderma
- (2008) Fredrick M. Wigley CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Induction of Immunological Tolerance by Apoptotic Cells Requires Caspase-Dependent Oxidation of High-Mobility Group Box-1 Protein
- (2008) Hirotaka Kazama et al. IMMUNITY
- Clinical Significance of Serum HMGB-1 and sRAGE Levels in Systemic Sclerosis: Association with Disease Severity
- (2008) Ayumi Yoshizaki et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis
- (2008) Melanie Königshoff et al. PLoS One
- Vascular Disease in Scleroderma: Mechanisms of Vascular Injury
- (2008) Bashar Kahaleh RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
- The Pathology of Scleroderma Vascular Disease
- (2008) Jo Nadine Fleming et al. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
- Mechanisms of vascular damage in SSc--implications for vascular treatment strategies
- (2008) S. Guiducci et al. RHEUMATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started