Interferon-γ promotes vascular remodeling in human microvascular endothelial cells by upregulating endothelin (ET)-1 and transforming growth factor (TGF) β2

Bosentan Treatment for Raynaud's Phenomenon and Skin Fibrosis in Patients with Systemic Sclerosis and Pulmonary Arterial Hypertension: An Open-Label, Observational, Retrospective Study

(2017) N. Giordano et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Evaluation of the Effect of Bosentan Treatment on Proinflammatory Cytokine Serum Levels in Patients Affected by Systemic Sclerosis

(2017) F. Bellisai et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Association of Interferon-Gamma Gene Polymorphism (+874 T/A) with Systemic Sclerosis

(2013) Isabela J. Wastowski et al.   DISEASE MARKERS

Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders

(2011) Sonsoles Piera-Velazquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Inflammation-Induced Endothelial-to-Mesenchymal Transition

(2011) Florian Rieder et al.   AMERICAN JOURNAL OF PATHOLOGY

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

(2011) B. W. Higgs et al.   ANNALS OF THE RHEUMATIC DISEASES

Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitro

(2011) Zhaodong Li et al.   ARTHRITIS AND RHEUMATISM

Effects of bosentan on nondigital ulcers in patients with systemic sclerosis

(2011) T. Taniguchi et al.   BRITISH JOURNAL OF DERMATOLOGY

IFN-γ and TNF-α induce a different modulation of interleukin-6 in systemic sclerosis fibroblasts compared to healthy controls

(2011) A Antonelli et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Dysregulated expression of MIG/CXCL9, IP-10/CXCL10 and CXCL16 and their receptors in systemic sclerosis

(2011) Bradley J Rabquer et al.   ARTHRITIS RESEARCH & THERAPY

Endothelial Fli1 Deficiency Impairs Vascular Homeostasis

(2010) Yoshihide Asano et al.   AMERICAN JOURNAL OF PATHOLOGY

Noncanonical Wnt signaling in vertebrate development, stem cells, and diseases

(2010) Ryohichi Sugimura et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Endothelial Cell–Derived Endothelin-1 Promotes Cardiac Fibrosis in Diabetic Hearts Through Stimulation of Endothelial-to-Mesenchymal Transition

(2010) Bambang Widyantoro et al.   CIRCULATION

Pulmonary microvascular endothelial cells from bleomycin-induced rats promote the transformation and collagen synthesis of fibroblasts

(2010) Qian Yin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Conversion of vascular endothelial cells into multipotent stem-like cells

(2010) Damian Medici et al.   NATURE MEDICINE

Cellular and molecular aspects of vascular dysfunction in systemic sclerosis

(2010) Maria Trojanowska   Nature Reviews Rheumatology

Innate immunity and inflammation in systemic sclerosis

(2009) Robert Lafyatis et al.   CURRENT OPINION IN RHEUMATOLOGY

Interferon-γ: A historical perspective

(2009) Alfons Billiau et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases

(2009) Xiaoyu Hu et al.   IMMUNITY

Raynaud's Phenomenon and Plasma Endothelin: Correlations with Capillaroscopic Patterns in Systemic Sclerosis

(2009) A. SULLI et al.   JOURNAL OF RHEUMATOLOGY

Is scleroderma a vasculopathy?

(2009) Jo Nadine Fleming et al.   Current Rheumatology Reports

Cytokine regulation of tight junctions

(2008) Christopher T. Capaldo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Capillary Regeneration in Scleroderma: Stem Cell Therapy Reverses Phenotype?

(2008) Jo N. Fleming et al.   PLoS One

Vascular Disease in Scleroderma: Mechanisms of Vascular Injury

(2008) Bashar Kahaleh   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

CXCL10 ( ) and CCL2 ( ) chemokines in systemic sclerosis a longitudinal study

(2007) A. Antonelli et al.   RHEUMATOLOGY