Role of Cellular Senescence and NOX4-Mediated Oxidative Stress in Systemic Sclerosis Pathogenesis
出版年份 2014 全文链接
标题
Role of Cellular Senescence and NOX4-Mediated Oxidative Stress in Systemic Sclerosis Pathogenesis
作者
关键词
Systemic sclerosis, Fibrosis, Cellular senescence, Oxidative stress, ROS, NOX4
出版物
Current Rheumatology Reports
Volume 17, Issue 1, Pages -
出版商
Springer Nature
发表日期
2014-12-04
DOI
10.1007/s11926-014-0473-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement
- (2015) Sebastian Altenhöfer et al. ANTIOXIDANTS & REDOX SIGNALING
- ROS Function in Redox Signaling and Oxidative Stress
- (2014) Michael Schieber et al. CURRENT BIOLOGY
- A far-upstream AP-1/Smad binding box regulates human NOX4 promoter activation by transforming growth factor-β
- (2014) Guangxing Bai et al. GENE
- Cellular senescence and its effector programs
- (2014) R. Salama et al. GENES & DEVELOPMENT
- Altered MCM Protein Levels and Autophagic Flux in Aged and Systemic Sclerosis Dermal Fibroblasts
- (2014) Verónica I. Dumit et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Molecular and cellular basis of scleroderma
- (2014) Beate Eckes et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- Cellular mechanisms and physiological consequences of redox-dependent signalling
- (2014) Kira M. Holmström et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cellular senescence: from physiology to pathology
- (2014) Daniel Muñoz-Espín et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension
- (2014) Francesco Boin et al. Orphanet Journal of Rare Diseases
- Oxidative DNA damage induces the ATM-mediated transcriptional suppression of the Wnt inhibitor WIF-1 in systemic sclerosis and fibrosis
- (2014) S. Svegliati et al. Science Signaling
- Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance
- (2014) L. Hecker et al. Science Translational Medicine
- Evaluation of oxidant and antioxidant status and relation with prolidase in systemic sclerosis
- (2014) Esen Savas et al. WIENER KLINISCHE WOCHENSCHRIFT
- Redox Signaling as a Therapeutic Target to Inhibit Myofibroblast Activation in Degenerative Fibrotic Disease
- (2014) Natalie Sampson et al. Biomed Research International
- NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses
- (2014) Fan Jiang et al. Redox Biology
- Nox Enzymes and New Thinking on Reactive Oxygen: A Double-Edged Sword Revisited
- (2013) J. David Lambeth et al. Annual Review of Pathology-Mechanisms of Disease
- Role of NADPH Oxidases in Liver Fibrosis
- (2013) Yong-Han Paik et al. ANTIOXIDANTS & REDOX SIGNALING
- Myofibroblast Differentiation: Main Features, Biomedical Relevance, and the Role of Reactive Oxygen Species
- (2013) Alessandro Siani et al. ANTIOXIDANTS & REDOX SIGNALING
- NADPH oxidase enzymes in skin fibrosis: molecular targets and therapeutic agents
- (2013) Olubukola Babalola et al. ARCHIVES OF DERMATOLOGICAL RESEARCH
- Review: Evidence That Systemic Sclerosis Is a Vascular Disease
- (2013) Marco Matucci-Cerinic et al. ARTHRITIS AND RHEUMATISM
- Mechanistic links between aging and lung fibrosis
- (2013) Victor J. Thannickal BIOGERONTOLOGY
- Programmed Cell Senescence during Mammalian Embryonic Development
- (2013) Daniel Muñoz-Espín et al. CELL
- Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
- (2013) Mekayla Storer et al. CELL
- Accelerated telomere shortening in rheumatic diseases: cause or consequence?
- (2013) Amina ZA Dehbi et al. Expert Review of Clinical Immunology
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- (2013) Tamara Tchkonia et al. JOURNAL OF CLINICAL INVESTIGATION
- Role of caveolin-1 in fibrotic diseases
- (2013) David Gvaramia et al. MATRIX BIOLOGY
- Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema
- (2013) Marco Chilosi et al. Translational Research
- Caveolin-1 Deficiency Protects from Pulmonary Fibrosis by Modulating Epithelial Cell Senescence in Mice
- (2012) Pooja Shivshankar et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Molecular Mechanisms in Progressive Idiopathic Pulmonary Fibrosis
- (2012) Mark P. Steele et al. Annual Review of Medicine
- Towards specific NADPH oxidase inhibition by small synthetic peptides
- (2012) Jamel El-Benna et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The NOX toolbox: validating the role of NADPH oxidases in physiology and disease
- (2012) Sebastian Altenhöfer et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent
- (2012) Tomonori Aoyama et al. HEPATOLOGY
- The Organotelluride Catalyst (PHTE)2NQ Prevents HOCl-Induced Systemic Sclerosis in Mouse
- (2012) Wioleta K. Marut et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Pathogenesis of Systemic Sclerosis
- (2011) Tamiko R. Katsumoto et al. Annual Review of Pathology-Mechanisms of Disease
- The specific free radical scavenger edaravone suppresses fibrosis in the bleomycin-induced and tight skin mouse models of systemic sclerosis
- (2011) Ayumi Yoshizaki et al. ARTHRITIS AND RHEUMATISM
- Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts
- (2011) Pei-Suen Tsou et al. ARTHRITIS AND RHEUMATISM
- Design, synthesis and biological activity of original pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors
- (2011) Francesca Gaggini et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
- (2011) Antero Salminen et al. CELLULAR SIGNALLING
- Increasing levels of serum antioxidant status, total antioxidant power, in systemic sclerosis
- (2011) Fumihide Ogawa et al. CLINICAL RHEUMATOLOGY
- NADPH oxidase inhibitors: a patent review
- (2011) Jung-Ae Kim et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Signal transduction by reactive oxygen species
- (2011) Toren Finkel JOURNAL OF CELL BIOLOGY
- Loss of PTEN Expression by Dermal Fibroblasts Causes Skin Fibrosis
- (2011) Sunil K. Parapuram et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases
- (2011) Jeffrey L. Barnes et al. KIDNEY INTERNATIONAL
- Differential Roles for the Interferon-Inducible IFI16 and AIM2 Innate Immune Sensors for Cytosolic DNA in Cellular Senescence of Human Fibroblasts
- (2011) X. Duan et al. MOLECULAR CANCER RESEARCH
- Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities
- (2011) Swati Bhattacharyya et al. Nature Reviews Rheumatology
- Trends in mortality in patients with systemic sclerosis over 40 years: a systematic review and meta-analysis of cohort studies
- (2011) M. Elhai et al. RHEUMATOLOGY
- Impact of cellular senescence signature on ageing research
- (2010) Ewa Sikora et al. AGEING RESEARCH REVIEWS
- Pathologic Caveolin-1 Regulation of PTEN in Idiopathic Pulmonary Fibrosis
- (2010) Hong Xia et al. AMERICAN JOURNAL OF PATHOLOGY
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Deciphering the intricate regulatory mechanisms for the cellular choice between cell repair, apoptosis or senescence in response to damaging signals
- (2010) Adnan Erol CELLULAR SIGNALLING
- Oncogene-induced senescence: the bright and dark side of the response
- (2010) Vassilis G Gorgoulis et al. CURRENT OPINION IN CELL BIOLOGY
- The essence of senescence
- (2010) T. Kuilman et al. GENES & DEVELOPMENT
- First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
- (2010) Benoı̂t Laleu et al. JOURNAL OF MEDICINAL CHEMISTRY
- High DNA Oxidative Damage in Systemic Sclerosis
- (2010) J. AVOUAC et al. JOURNAL OF RHEUMATOLOGY
- Feedback between p21 and reactive oxygen production is necessary for cell senescence
- (2010) João F Passos et al. Molecular Systems Biology
- Telomere Lengths, Pulmonary Fibrosis and Telomerase (TERT) Mutations
- (2010) Alberto Diaz de Leon et al. PLoS One
- Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate
- (2010) A. Dooley et al. RHEUMATOLOGY
- Increased cysteinyl-leukotrienes and 8-isoprostane in exhaled breath condensate from systemic sclerosis patients
- (2010) E. Tufvesson et al. RHEUMATOLOGY
- NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGF 1-induced fibroblast differentiation into myofibroblasts
- (2010) N. Amara et al. THORAX
- Inflammatory networks during cellular senescence: causes and consequences
- (2010) Adam Freund et al. TRENDS IN MOLECULAR MEDICINE
- Cellular senescence: unravelling complexity
- (2009) João F. Passos et al. AGE
- Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells
- (2009) Alicia N. Lyle et al. CIRCULATION RESEARCH
- NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts
- (2009) C. D. Bondi et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
- (2009) Louise Hecker et al. NATURE MEDICINE
- Scleroderma
- (2009) Armando Gabrielli et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo
- (2008) Elena Tourkina et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Association of increased telomere lengths in limited scleroderma, with a lack of age-related telomere erosion
- (2008) A MacIntyre et al. ANNALS OF THE RHEUMATIC DISEASES
- Cellular Senescence: Molecular Mechanisms, In Vivo Significance, and Redox Considerations
- (2008) Michael Muller ANTIOXIDANTS & REDOX SIGNALING
- Decreased expression of caveolin 1 in patients with systemic sclerosis: Crucial role in the pathogenesis of tissue fibrosis
- (2008) Francesco Del Galdo et al. ARTHRITIS AND RHEUMATISM
- Caveolin-1, transforming growth factor-β receptor internalization, and the pathogenesis of systemic sclerosis
- (2008) Francesco Del Galdo et al. CURRENT OPINION IN RHEUMATOLOGY
- Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species
- (2008) Hideki Sumimoto FEBS Journal
- Increased Serum Levels of Ne-(hexanoyl)lysine, A New Marker of Oxidative Stress, in Systemic Sclerosis
- (2008) Kazuhiro Shimizu et al. JOURNAL OF RHEUMATOLOGY
- Expression of an IFN-Inducible Cellular Senescence Gene, IFI16, Is Up-Regulated by p53
- (2008) L. L. Song et al. MOLECULAR CANCER RESEARCH
- Oxidative stress and the pathogenesis of scleroderma: the Murrell’s hypothesis revisited
- (2008) Armando Gabrielli et al. Seminars in Immunopathology
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now