Fibrosis, Vascular Activation, and Immune Abnormalities Resembling Systemic Sclerosis in Bleomycin-Treated Fli-1-Haploinsufficient Mice

Brief Report: Fibrosis Caused by Loss of PTEN Expression in Mouse Fibroblasts Is Crucially Dependent on CCN2

(2013) Shangxi Liu et al.   ARTHRITIS AND RHEUMATISM

Cell plasticity in wound healing: paracrine factors of M1/ M2 polarized macrophages influence the phenotypical state of dermal fibroblasts

(2013) Diana TA Ploeger et al.   Cell Communication and Signaling

The Role of Peritoneal Alternatively Activated Macrophages in the Process of Peritoneal Fibrosis Related to Peritoneal Dialysis

(2013) Jie Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interferon-γ promotes vascular remodeling in human microvascular endothelial cells by upregulating endothelin (ET)-1 and transforming growth factor (TGF) β2

(2013) Izabela Chrobak et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

(2013) Neil C Henderson et al.   NATURE MEDICINE

Decreased cathepsin V expression due to Fli1 deficiency contributes to the development of dermal fibrosis and proliferative vasculopathy in systemic sclerosis

(2013) S. Noda et al.   RHEUMATOLOGY

Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism

(2013) Edwin SL Chan et al.   ARTHRITIS RESEARCH & THERAPY

Animal Models of Scleroderma: Current State and Recent Development

(2013) Yoshihide Asano et al.   Current Rheumatology Reports

A Possible Contribution of Altered Cathepsin B Expression to the Development of Skin Sclerosis and Vasculopathy in Systemic Sclerosis

(2012) Shinji Noda et al.   PLoS One

CCN2 Is Required for the TGF-β Induced Activation of Smad1 - Erk1/2 Signaling Network

(2011) Sashidhar S. Nakerakanti et al.   PLoS One

Endothelial Fli1 Deficiency Impairs Vascular Homeostasis

(2010) Yoshihide Asano et al.   AMERICAN JOURNAL OF PATHOLOGY

CCN2 is required for bleomycin-induced skin fibrosis in mice

(2010) Shangxi Liu et al.   ARTHRITIS AND RHEUMATISM

Mast cells are a source of transforming growth factor β in systemic sclerosis

(2010) Thomas Hügle et al.   ARTHRITIS AND RHEUMATISM

Future treatments in systemic sclerosis

(2010) Yoshihide ASANO   JOURNAL OF DERMATOLOGY

Cell Adhesion Molecules Regulate Fibrotic Process via Th1/Th2/Th17 Cell Balance in a Bleomycin-Induced Scleroderma Model

(2010) A. Yoshizaki et al.   JOURNAL OF IMMUNOLOGY

Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype

(2010) Susan K Mathai et al.   LABORATORY INVESTIGATION

Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis

(2010) Nobuyo Higashi-Kuwata et al.   ARTHRITIS RESEARCH & THERAPY

Endothelial–Mesenchymal Transition as a Novel Mechanism for Generating Myofibroblasts during Diabetic Nephropathy

(2009) Akane Kizu et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial-Myofibroblast Transition Contributes to the Early Development of Diabetic Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice

(2009) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial–Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis

(2009) Naozumi Hashimoto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Phosphorylation of Fli1 at Threonine 312 by Protein Kinase C   Promotes Its Interaction with p300/CREB-Binding Protein-Associated Factor and Subsequent Acetylation in Response to Transforming Growth Factor  

(2009) Y. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY

CD19 Regulates Skin and Lung Fibrosis via Toll-Like Receptor Signaling in a Model of Bleomycin-Induced Scleroderma

(2008) Ayumi Yoshizaki et al.   AMERICAN JOURNAL OF PATHOLOGY

Transcription Factor Fli1 Regulates Collagen Fibrillogenesis in Mouse Skin

(2008) Y. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY