标题
Metabolomics in rheumatic diseases: desperately seeking biomarkers
作者
关键词
-
出版物
Nature Reviews Rheumatology
Volume 12, Issue 5, Pages 269-281
出版商
Springer Nature
发表日期
2016-03-03
DOI
10.1038/nrrheum.2016.1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- PI3K inhibitors in inflammation, autoimmunity and cancer
- (2015) Anne-Katrien Stark et al. CURRENT OPINION IN PHARMACOLOGY
- Lipid Metabolism, Apoptosis and Cancer Therapy
- (2015) Chunfa Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metabolic analysis of knee synovial fluid as a potential diagnostic approach for osteoarthritis
- (2015) Beata Mickiewicz et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Relationship Between Blood Plasma and Synovial Fluid Metabolite Concentrations in Patients with Osteoarthritis
- (2015) W. Zhang et al. JOURNAL OF RHEUMATOLOGY
- Optimized Analytical Procedures for the Untargeted Metabolomic Profiling of Human Urine and Plasma by Combining Hydrophilic Interaction (HILIC) and Reverse-Phase Liquid Chromatography (RPLC)–Mass Spectrometry
- (2015) Kévin Contrepois et al. MOLECULAR & CELLULAR PROTEOMICS
- Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
- (2015) Rupert Courtnay et al. MOLECULAR BIOLOGY REPORTS
- Fatty acid metabolism in the regulation of T cell function
- (2015) Matthias Lochner et al. TRENDS IN IMMUNOLOGY
- Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions
- (2015) Clovis S. Palmer et al. Frontiers in Immunology
- Metabolomics analysis of collagen-induced arthritis in rats and interventional effects of oral tolerance
- (2014) Xinghong Ding et al. ANALYTICAL BIOCHEMISTRY
- Evaluation of Fast 2D NMR for Metabolomics
- (2014) Adrien Le Guennec et al. ANALYTICAL CHEMISTRY
- Choline kinase inhibition in rheumatoid arthritis
- (2014) M Guma et al. ANNALS OF THE RHEUMATIC DISEASES
- Recent advances in the reconstruction of metabolic models and integration of omics data
- (2014) Rajib Saha et al. CURRENT OPINION IN BIOTECHNOLOGY
- Metabolism of activated T lymphocytes
- (2014) Jason A Maciolek et al. CURRENT OPINION IN IMMUNOLOGY
- Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients
- (2014) Georgia McDonald et al. JOURNAL OF CLINICAL INVESTIGATION
- Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice
- (2014) Fei Xiao et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Metabolism of stromal and immune cells in health and disease
- (2014) Bart Ghesquière et al. NATURE
- Constraint-based models predict metabolic and associated cellular functions
- (2014) Aarash Bordbar et al. NATURE REVIEWS GENETICS
- Persisting eicosanoid pathways in rheumatic diseases
- (2014) Marina Korotkova et al. Nature Reviews Rheumatology
- Rapid Resolution Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics Approach to Study the Effects of Jieduquyuziyin Prescription on Systemic Lupus Erythematosus
- (2014) Xinghong Ding et al. PLoS One
- Global Metabolite Profiling of Synovial Fluid for the Specific Diagnosis of Rheumatoid Arthritis from Other Inflammatory Arthritis
- (2014) Sooah Kim et al. PLoS One
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- Classification of osteoarthritis phenotypes by metabolomics analysis
- (2014) Weidong Zhang et al. BMJ Open
- Metabolic Regulation of T Lymphocytes
- (2013) Nancie J. MacIver et al. Annual Review of Immunology
- Metabolic Profiling Predicts Response to Anti-Tumor Necrosis Factor α Therapy in Patients With Rheumatoid Arthritis
- (2013) Sabrina R. Kapoor et al. ARTHRITIS AND RHEUMATISM
- The Impact of Inflammation on Metabolomic Profiles in Patients With Arthritis
- (2013) Stephen P. Young et al. ARTHRITIS AND RHEUMATISM
- A Lipidomic Study of Phospholipid Classes and Species in Human Synovial Fluid
- (2013) Marta Krystyna Kosinska et al. ARTHRITIS AND RHEUMATISM
- Metabolomics in rheumatic diseases: The potential of an emerging methodology for improved patient diagnosis, prognosis, and treatment efficacy
- (2013) Roberta Priori et al. AUTOIMMUNITY REVIEWS
- Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer
- (2013) Krushna C. Patra et al. CANCER CELL
- Immune-suppressive properties of the tumor microenvironment
- (2013) Jürgen C. Becker et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Influence of Metabolism on Epigenetics and Disease
- (2013) William G. Kaelin et al. CELL
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- New Advances in Separation Science for Metabolomics: Resolving Chemical Diversity in a Post-Genomic Era
- (2013) Naomi L. Kuehnbaum et al. CHEMICAL REVIEWS
- Pharmacometabolomics: Implications for Clinical Pharmacology and Systems Pharmacology
- (2013) R Kaddurah-Daouk et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Sphingosine 1-phosphate receptor agonists: a patent review (2010 – 2012)
- (2013) Edward Roberts et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Current immunotherapy in rheumatoid arthritis
- (2013) Florian MP Meier et al. Immunotherapy
- Lactate Engages Receptor Tyrosine Kinases Axl, Tie2, and Vascular Endothelial Growth Factor Receptor 2 to Activate Phosphoinositide 3-Kinase/Akt and Promote Angiogenesis
- (2013) Guo-Xiang Ruan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Liquid chromatography–mass spectrometry in metabolomics research: Mass analyzers in ultra high pressure liquid chromatography coupling
- (2013) Sara Forcisi et al. JOURNAL OF CHROMATOGRAPHY A
- Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells
- (2013) Zhen Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Serum Metabolic Signatures of Four Types of Human Arthritis
- (2013) Miao Jiang et al. JOURNAL OF PROTEOME RESEARCH
- Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
- (2013) Nicholas Arpaia et al. NATURE
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Magnetic resonance imaging of tumor glycolysis using hyperpolarized 13C-labeled glucose
- (2013) Tiago B Rodrigues et al. NATURE MEDICINE
- Metabolic targets for cancer therapy
- (2013) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- The Human Urine Metabolome
- (2013) Souhaila Bouatra et al. PLoS One
- Metabolomics of the Tumor Microenvironment in Pediatric Acute Lymphoblastic Leukemia
- (2013) Stefano Tiziani et al. PLoS One
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- Metabolism in physiological cell proliferation and differentiation
- (2013) Michalis Agathocleous et al. TRENDS IN CELL BIOLOGY
- Succinate: a metabolic signal in inflammation
- (2013) Evanna Mills et al. TRENDS IN CELL BIOLOGY
- Targeting cellular metabolism to improve cancer therapeutics
- (2013) Y Zhao et al. Cell Death & Disease
- Stable Isotope-Assisted Metabolomics for Network-Wide Metabolic Pathway Elucidation
- (2012) Darren J. Creek et al. ANALYTICAL CHEMISTRY
- Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS
- (2012) Martin Giera et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas
- (2012) F Seguin et al. BRITISH JOURNAL OF CANCER
- Gut Microbiota Composition and Activity in Relation to Host Metabolic Phenotype and Disease Risk
- (2012) Elaine Holmes et al. Cell Metabolism
- Breathless cancer cells get fat on glutamine
- (2012) Dimitrios Anastasiou et al. CELL RESEARCH
- Stable isotope-assisted metabolomics to detect metabolic flux changes in mammalian cell cultures
- (2012) Daniel Mueller et al. CURRENT OPINION IN BIOTECHNOLOGY
- Metabolomics platforms for genome wide association studies—linking the genome to the metabolome
- (2012) Jerzy Adamski et al. CURRENT OPINION IN BIOTECHNOLOGY
- The gut microbiota elicits a profound metabolic reorientation in the mouse jejunal mucosa during conventionalisation
- (2012) Sahar El Aidy et al. GUT
- Metabolic reprogramming and metabolic dependency in T cells
- (2012) Ruoning Wang et al. IMMUNOLOGICAL REVIEWS
- 3-bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective “small molecule” anti-cancer agent taken from labside to bedside: introduction to a special issue
- (2012) Peter L. Pedersen JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug
- (2012) Simone Cardaci et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Recent developments in liquid chromatography–mass spectrometry and related techniques
- (2012) Michal Holčapek et al. JOURNAL OF CHROMATOGRAPHY A
- Liquid chromatography–nuclear magnetic resonance coupling as alternative to liquid chromatography–mass spectrometry hyphenations: Curious option or powerful and complementary routine tool?
- (2012) Sonja Sturm et al. JOURNAL OF CHROMATOGRAPHY A
- Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis
- (2012) Ioanna Nikitopoulou et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism
- (2012) Sonja C. Schriever et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo
- (2012) Y. Liu et al. MOLECULAR CANCER THERAPEUTICS
- How cancer metabolism is tuned for proliferation and vulnerable to disruption
- (2012) Almut Schulze et al. NATURE
- Metabolomics: the apogee of the omics trilogy
- (2012) Gary J. Patti et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Pathogenic role of autotaxin and LPA
- (2012) Emma Leah Nature Reviews Rheumatology
- Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors
- (2012) Nunzio Bottini et al. Nature Reviews Rheumatology
- HMDB 3.0—The Human Metabolome Database in 2013
- (2012) David S. Wishart et al. NUCLEIC ACIDS RESEARCH
- Metabolic Disturbances Associated with Systemic Lupus Erythematosus
- (2012) Tianfu Wu et al. PLoS One
- Characterization of Rheumatoid Arthritis Subtypes Using Symptom Profiles, Clinical Chemistry and Metabolomics Measurements
- (2012) Herman A. van Wietmarschen et al. PLoS One
- Impact of sphingosine kinase 2 deficiency on the development of TNF-alpha-induced inflammatory arthritis
- (2012) DeAnna A. Baker et al. RHEUMATOLOGY INTERNATIONAL
- Host-Gut Microbiota Metabolic Interactions
- (2012) J. K. Nicholson et al. SCIENCE
- Genome-wide association studies with metabolomics
- (2012) Jerzy Adamski Genome Medicine
- Highly Sensitive GC/MS/MS Method for Quantitation of Amino and Nonamino Organic Acids
- (2011) Hans F. N. Kvitvang et al. ANALYTICAL CHEMISTRY
- High sensitivity quantitative lipidomics analysis of fatty acids in biological samples by gas chromatography–mass spectrometry
- (2011) Oswald Quehenberger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Elucidation of Cellular Metabolism Via Metabolomics and Stable-Isotope Assisted Metabolomics
- (2011) Karsten Hiller et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- A high-resolution NMR probe in which the coil and preamplifier are cooled with liquid helium
- (2011) P. Styles et al. JOURNAL OF MAGNETIC RESONANCE
- Therapeutic targeting of cancer cell metabolism
- (2011) Chi V. Dang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- 1H NMR-based metabolomic study of metabolic profiling for systemic lupus erythematosus
- (2011) X Ouyang et al. LUPUS
- Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses
- (2011) Xianlin Han et al. MASS SPECTROMETRY REVIEWS
- Discovery of Candidate Serum Proteomic and Metabolomic Biomarkers in Ankylosing Spondylitis
- (2011) Roman Fischer et al. MOLECULAR & CELLULAR PROTEOMICS
- Targeting cancer metabolism: a therapeutic window opens
- (2011) Matthew G. Vander Heiden NATURE REVIEWS DRUG DISCOVERY
- The Human Plasma Lipidome
- (2011) Oswald Quehenberger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Global metabolic profiling of human osteoarthritic synovium
- (2011) S.B. Adams et al. OSTEOARTHRITIS AND CARTILAGE
- Mitochondrial Metabolism Inhibitors for Cancer Therapy
- (2011) Emma E. Ramsay et al. PHARMACEUTICAL RESEARCH
- The Human Serum Metabolome
- (2011) Nikolaos Psychogios et al. PLoS One
- Diagnostic properties of metabolic perturbations in rheumatoid arthritis
- (2011) Rasmus K Madsen et al. ARTHRITIS RESEARCH & THERAPY
- Identification of urinary metabolites that distinguish membranous lupus nephritis from proliferative lupus nephritis and focal segmental glomerulosclerosis
- (2011) Lindsey E Romick-Rosendale et al. ARTHRITIS RESEARCH & THERAPY
- Metabolomic high-content nuclear magnetic resonance-based drug screening of a kinase inhibitor library
- (2011) Stefano Tiziani et al. Nature Communications
- Advances in NMR-based biofluid analysis and metabolite profiling
- (2010) Shucha Zhang et al. ANALYST
- Targeted Metabolomics for Biomarker Discovery
- (2010) William J. Griffiths et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis
- (2010) G. Zhai et al. ANNALS OF THE RHEUMATIC DISEASES
- Simvastatin induces derepression of PTEN expression via NFκB to inhibit breast cancer cell growth
- (2010) Nayana Ghosh-Choudhury et al. CELLULAR SIGNALLING
- De NovoLipogenesis Maintains Vascular Homeostasis through Endothelial Nitric-oxide Synthase (eNOS) Palmitoylation
- (2010) Xiaochao Wei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MassBank: a public repository for sharing mass spectral data for life sciences
- (2010) Hisayuki Horai et al. JOURNAL OF MASS SPECTROMETRY
- Combination therapy targeting cancer metabolism
- (2010) Justin B. Wenger et al. MEDICAL HYPOTHESES
- Sphingosine-1-phosphate: a potential therapeutic target for rheumatoid arthritis
- (2010) Peng-fei Hu et al. MOLECULAR BIOLOGY REPORTS
- NMR of natural products at the ‘nanomole-scale’
- (2010) Tadeusz F. Molinski NATURAL PRODUCT REPORTS
- Chemistry: Breaking the billion-hertz barrier
- (2010) Ananyo Bhattacharya NATURE
- Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
- (2010) A. Le et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis
- (2009) Daniel K. Nomura et al. CELL
- CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models
- (2009) W Schneiderhan et al. GUT
- Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotope-resolved metabolomics (SIRM)
- (2009) Teresa WM Fan et al. Molecular Cancer
- Extracellular redox modulation by regulatory T cells
- (2009) Zhonghua Yan et al. Nature Chemical Biology
- Integrated GC–MS and LC–MS plasma metabonomics analysis of ankylosing spondylitis
- (2008) Peng Gao et al. ANALYST
- Highly sensitive feature detection for high resolution LC/MS
- (2008) Ralf Tautenhahn et al. BMC BIOINFORMATICS
- Cancer Cell Metabolism: Warburg and Beyond
- (2008) Peggy P. Hsu et al. CELL
- International NMR-Based Environmental Metabolomics Intercomparison Exercise
- (2008) Mark R. Viant et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: Implications in cancer therapy
- (2008) Ana Ramírez de Molina et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Stable isotope-assisted metabolomics in cancer research
- (2008) Andrew N. Lane et al. IUBMB LIFE
- Specific and overlapping sphingosine-1-phosphate receptor functions in human synoviocytes: impact of TNF-α
- (2008) Chenqi Zhao et al. JOURNAL OF LIPID RESEARCH
- Update of the LIPID MAPS comprehensive classification system for lipids
- (2008) Eoin Fahy et al. JOURNAL OF LIPID RESEARCH
- Metabolic Profiling of Human Colorectal Cancer Using High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS NMR) Spectroscopy and Gas Chromatography Mass Spectrometry (GC/MS)
- (2008) Eric Chun Yong Chan et al. JOURNAL OF PROTEOME RESEARCH
- Metabolite identification via the Madison Metabolomics Consortium Database
- (2008) Qiu Cui et al. NATURE BIOTECHNOLOGY
- Lipid signalling in disease
- (2008) Matthias P. Wymann et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Quantitative metabolomics using NMR
- (2008) David S. Wishart TRAC-TRENDS IN ANALYTICAL CHEMISTRY
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