标题
Immune-suppressive properties of the tumor microenvironment
作者
关键词
A disintegrin and metalloproteinase (ADAM), Indoleamine-2,3-dioxygenase (IDO), Arginase, Hypoxia, Adenosine, Natural killer group 2 member D (NKG2D) ligands
出版物
CANCER IMMUNOLOGY IMMUNOTHERAPY
Volume 62, Issue 7, Pages 1137-1148
出版商
Springer Nature
发表日期
2013-05-10
DOI
10.1007/s00262-013-1434-6
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Effect of NKG2D ligand expression on host immune responses
- (2015) Marine Champsaur et al. IMMUNOLOGICAL REVIEWS
- Cutting Edge: The Metalloproteinase ADAM17/TNF- -Converting Enzyme Regulates Proteolytic Shedding of the MHC Class I-Related Chain B Protein
- (2014) P. Boutet et al. JOURNAL OF IMMUNOLOGY
- Tumor-Secreted Lactic Acid Promotes IL-23/IL-17 Proinflammatory Pathway
- (2014) H. Shime et al. JOURNAL OF IMMUNOLOGY
- Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes)
- (2013) Theresa L. Whiteside BIOCHEMICAL SOCIETY TRANSACTIONS
- Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial†
- (2012) M. Reck et al. ANNALS OF ONCOLOGY
- The expression, function, and clinical relevance of B7 family members in cancer
- (2012) Barbara Seliger et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The specific targeting of immune regulation: T-cell responses against Indoleamine 2,3-dioxygenase
- (2012) Mads Hald Andersen CANCER IMMUNOLOGY IMMUNOTHERAPY
- Assessment of association between BRAF-V600E mutation status in melanomas and clinical response to ipilimumab
- (2012) Vafa Shahabi et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion
- (2012) M. Platten et al. CANCER RESEARCH
- Cellular Constituents of Immune Escape within the Tumor Microenvironment
- (2012) S. P. Kerkar et al. CANCER RESEARCH
- A Landscape of Driver Mutations in Melanoma
- (2012) Eran Hodis et al. CELL
- Immunoregulatory molecules are master regulators of inflammation during the immune response
- (2012) Hortensia de la Fuente et al. FEBS LETTERS
- Tryptophan hydroxylase-1 regulates immune tolerance and inflammation
- (2012) Elizabeth C. Nowak et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tumor-Expressed Inducible Nitric Oxide Synthase Controls Induction of Functional Myeloid-Derived Suppressor Cells through Modulation of Vascular Endothelial Growth Factor Release
- (2012) P. Jayaraman et al. JOURNAL OF IMMUNOLOGY
- Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial
- (2012) Anna Maria Di Giacomo et al. LANCET ONCOLOGY
- Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma
- (2012) Michael A. Postow et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase
- (2012) L. Pilotte et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Raising the Bar: The Curative Potential of Human Cancer Immunotherapy
- (2012) S. A. Rosenberg Science Translational Medicine
- Recent advances on the role of tumor exosomes in immunosuppression and disease progression
- (2012) Paola Filipazzi et al. SEMINARS IN CANCER BIOLOGY
- CD73: a potent suppressor of antitumor immune responses
- (2012) Paul. A. Beavis et al. TRENDS IN IMMUNOLOGY
- Endogenous modulators of inflammatory cell recruitment
- (2012) George Hajishengallis et al. TRENDS IN IMMUNOLOGY
- IDO Is a Nodal Pathogenic Driver of Lung Cancer and Metastasis Development
- (2012) Courtney Smith et al. Cancer Discovery
- Hypoxia Promotes Tumor Growth in Linking Angiogenesis to Immune Escape
- (2012) Salem Chouaib et al. Frontiers in Immunology
- The role of the EP receptors for prostaglandin E2 in skin and skin cancer
- (2011) J. E. Rundhaug et al. CANCER AND METASTASIS REVIEWS
- Matrix Metalloproteinase-2 Conditions Human Dendritic Cells to Prime Inflammatory TH2 Cells via an IL-12- and OX40L-Dependent Pathway
- (2011) Emmanuelle Godefroy et al. CANCER CELL
- Suppression of T-cell responses by tumor metabolites
- (2011) Katrin Singer et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
- (2011) Adam T. Waickman et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity
- (2011) Sebastian F. M. Häusler et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- An immune-active tumor microenvironment favors clinical response to ipilimumab
- (2011) Rui-Ru Ji et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Human NK Cells Are Alerted to Induction of p53 in Cancer Cells by Upregulation of the NKG2D Ligands ULBP1 and ULBP2
- (2011) S. Textor et al. CANCER RESEARCH
- Hypoxia Induces Escape from Innate Immunity in Cancer Cells via Increased Expression of ADAM10: Role of Nitric Oxide
- (2011) I. B. Barsoum et al. CANCER RESEARCH
- Lactate: A Metabolic Key Player in Cancer
- (2011) F. Hirschhaeuser et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Indoleamine 2,3-Dioxygenase Expression in Human Cancers: Clinical and Immunologic Perspectives
- (2011) J. Godin-Ethier et al. CLINICAL CANCER RESEARCH
- Ipilimumab
- (2011) Fiona Cameron et al. DRUGS
- IL-17 + Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer
- (2011) Ilona Kryczek et al. JOURNAL OF IMMUNOLOGY
- Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells
- (2011) S. Ryzhov et al. JOURNAL OF IMMUNOLOGY
- Nitric oxide and redox mechanisms in the immune response
- (2011) David A. Wink et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Beyond Ipilimumab: New Approaches Target the Immunological Synapse
- (2011) K. Garber JNCI-Journal of the National Cancer Institute
- A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
- (2011) Omid Hamid et al. Journal of Translational Medicine
- Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma
- (2011) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Expression, signaling proficiency, and stimulatory function of the NKG2D lymphocyte receptor in human cancer cells
- (2011) A. C. Benitez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments
- (2011) Douglas D. Taylor et al. Seminars in Immunopathology
- ADAM17: a molecular switch to control inflammation and tissue regeneration
- (2011) Jürgen Scheller et al. TRENDS IN IMMUNOLOGY
- Receptor desensitization and blockade of the suppressive effects of prostaglandin E2 and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes
- (2010) Yunyun Su et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
- (2010) D. Jin et al. CANCER RESEARCH
- Tumors as Organs: Complex Tissues that Interface with the Entire Organism
- (2010) Mikala Egeblad et al. DEVELOPMENTAL CELL
- Hallmarks of cancer: Interactions with the tumor stroma
- (2010) Kristian Pietras et al. EXPERIMENTAL CELL RESEARCH
- Adenosine and Prostaglandin E2Cooperate in the Suppression of Immune Responses Mediated by Adaptive Regulatory T Cells
- (2010) Magis Mandapathil et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Extracellular adenosine triphosphate and adenosine in cancer
- (2010) J Stagg et al. ONCOGENE
- Anti–CTLA-4 Antibody Therapy: Immune Monitoring During Clinical Development of a Novel Immunotherapy
- (2010) Margaret K. Callahan et al. SEMINARS IN ONCOLOGY
- The Yin-Yang of Tumor-Associated Neutrophils
- (2009) Alberto Mantovani CANCER CELL
- Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
- (2009) F. Colotta et al. CARCINOGENESIS
- Differential Clinical Significance of Individual NKG2D Ligands in Melanoma: Soluble ULBP2 as an Indicator of Poor Prognosis Superior to S100B
- (2009) A. Paschen et al. CLINICAL CANCER RESEARCH
- Fine tuning the immune response through B7-H3 and B7-H4
- (2009) Kyung H. Yi et al. IMMUNOLOGICAL REVIEWS
- Hypoxia Increases Tumor Cell Shedding of MHC Class I Chain-Related Molecule: Role of Nitric Oxide
- (2008) D. R. Siemens et al. CANCER RESEARCH
- Tumor-Associated MICA Is Shed by ADAM Proteases
- (2008) I. Waldhauer et al. CANCER RESEARCH
- Induction of myeloid-derived suppressor cells by tumor exosomes
- (2008) Xiaoyu Xiang et al. INTERNATIONAL JOURNAL OF CANCER
- Suppressive Influences in the Immune Response to Cancer
- (2008) Vincenzo Bronte et al. JOURNAL OF IMMUNOTHERAPY
- More insights into the immunosuppressive potential of tumor exosomes
- (2008) Veronica Huber et al. Journal of Translational Medicine
- Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
- (2008) György Haskó et al. NATURE REVIEWS DRUG DISCOVERY
- CTLA-4 blockade increases IFN -producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients
- (2008) C. I. Liakou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer
- (2008) Jessica Pruessmeyer et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
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