Citronellal as a Promising Candidate for Alzheimer’s Disease Treatment: A Comprehensive Study on In Silico and In Vivo Anti-Acetylcholine Esterase Activity

Chemodiversity and α‐Glucosidase Activity of Eucalyptus Species from Northwestern Himalaya, India

(2023) Antim K. Maurya et al.   CHEMISTRY & BIODIVERSITY

The potential of lemon balm (Melissa officinalis L.) essential oil as an anti-anxiety agent – is the citronellal the activity carrier?

(2023) Nikola M. Stojanović et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Potential Neuroprotective Effect of Thymoquinone on Scopolamine-Induced In Vivo Alzheimer’s Disease-like Condition: Mechanistic Insights

(2023) Hend E. Abo Mansour et al.   MOLECULES

Donepezil-Inspired Multitargeting Indanone Derivatives as Effective Anti-Alzheimer’s Agents

(2022) Jatinder Vir Singh et al.   ACS Chemical Neuroscience

The antifungal and antibiofilm activity of Cymbopogon nardus essential oil and citronellal on clinical strains of Candida albicans

(2022) Leonardo Antunes Trindade et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Evaluation of antibacterial, antioxidant, cytotoxic, and acetylcholinesterase inhibition activities of novel [1,4] benzoxazepines fused to heterocyclic systems with a molecular modeling study

(2022) Ahmed Al-Mustafa et al.   MEDICINAL CHEMISTRY RESEARCH

Multitarget Biological Profiling of New Naphthoquinone and Anthraquinone-Based Derivatives for the Treatment of Alzheimer’s Disease

(2021) Marta Campora et al.   ACS Chemical Neuroscience

Cymbopogon nardus essential oil: a comprehensive review on its chemistry and bioactivity

(2021) Harneet Kaur et al.   JOURNAL OF ESSENTIAL OIL RESEARCH

In-silico strategies of some selected phytoconstituents from Melissa officinalis as SARS CoV-2 main protease and spike protein (COVID-19) inhibitors

(2021) D. S. N. B. K. Prasanth et al.   MOLECULAR SIMULATION

Activity of Selected Group of Monoterpenes in Alzheimer’s Disease Symptoms in Experimental Model Studies—A Non-Systematic Review

(2021) Karolina Wojtunik-Kulesza et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A combinatorial approach to screen structurally diverse acetylcholinesterase inhibitory plant secondary metabolites targeting Alzheimer’s disease

(2021) Gourav Choudhir et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Potential Therapeutic Effect of Citronellal on Diabetic Cardiomyopathy in Experimental Rats

(2021) Jun-Xiu Lu et al.   Evidence-based Complementary and Alternative Medicine

The Role of Macrophage Migration Inhibitory Factor in Alzheimer′s Disease: Conventionally Pathogenetic or Unconventionally Protective?

(2020) Maria Cristina Petralia et al.   MOLECULES

Design and Molecular dynamic Investigations of 7,8-Dihydroxyflavone Derivatives as Potential Neuroprotective Agents Against Alpha-synuclein

(2020) Mohankumar Thangavel et al.   Scientific Reports

The cytokine network in the pathogenesis of major depressive disorder. Close to translation?

(2020) Maria Cristina Petralia et al.   AUTOIMMUNITY REVIEWS

Linarin improves the dyskinesia recovery in Alzheimer's disease zebrafish by inhibiting the acetylcholinesterase activity

(2019) Hongye Pan et al.   LIFE SCIENCES

Isolation, identification, and quantification of Pentylcurcumene from Geophila repens: A new class of cholinesterase inhibitor for Alzheimer’s disease

(2019) Umesh Chandra Dash et al.   BIOORGANIC CHEMISTRY

Structural insights of metallo-beta-lactamase revealed an effective way of inhibition of enzyme by natural inhibitors

(2019) Bhavya Somalapura Gangadharappa et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

New Isoindole‐1,3‐dione Substituted Sulfonamides as Potent Inhibitors of Carbonic Anhydrase and Acetylcholinesterase: Design, Synthesis, and Biological Evaluation

(2019) Saliha Gündoğdu et al.   ChemistrySelect

The role of conserved QXG and binding affinity of S23G & S26G receptors on avian H5, swine H1 and human H1 of influenza A virus hemagglutinin

(2018) Panita Kongsune et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Combined in Vitro and in Silico Studies for the Anticholinesterase Activity and Pharmacokinetics of Coumarinyl Thiazoles and Oxadiazoles

(2018) Aliya Ibrar et al.   Frontiers in Chemistry

admetSAR 2.0: web-service for prediction and optimization of chemical ADMET properties

(2018) Hongbin Yang et al.   BIOINFORMATICS

Exploration of synthetic multifunctional amides as new therapeutic agents for Alzheimer's disease through enzyme inhibition, chemoinformatic properties, molecular docking and dynamic simulation insights

(2018) Mubashir Hassan et al.   JOURNAL OF THEORETICAL BIOLOGY

Ginsenosides: the need to move forward from bench to clinical trials

(2018) Seung Eun Yu et al.   Journal of Ginseng Research

The exploration of novel Alzheimer’s therapeutic agents from the pool of FDA approved medicines using drug repositioning, enzyme inhibition and kinetic mechanism approaches

(2018) Mubashir Hassan et al.   BIOMEDICINE & PHARMACOTHERAPY

Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer’s disease

(2018) Sushant K. Shrivastava et al.   BIOORGANIC CHEMISTRY

Scopolamine-induced greater alterations in neurochemical profile and increased oxidative stress demonstrated a better model of dementia: A comparative study

(2016) Saida Haider et al.   BRAIN RESEARCH BULLETIN

BACE1 molecular docking and anti-Alzheimer's disease activities of ginsenosides

(2016) Ran Joo Choi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Plant alkaloids as drug leads for Alzheimer's disease

(2015) Yu Pong Ng et al.   NEUROCHEMISTRY INTERNATIONAL

Prolonged altered mental status and bradycardia following pediatric donepezil ingestion

(2014) F. M. Garlich et al.   CLINICAL TOXICOLOGY

Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer’s Disease

(2014) Angel Agis-Torres et al.   Current Neuropharmacology

Antioxidant and antidepressant-like activities of semi-synthetic α-phenylseleno citronellal

(2014) Francine Novack Victoria et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

g_mmpbsa—A GROMACS Tool for High-Throughput MM-PBSA Calculations

(2014) Rashmi Kumari et al.   Journal of Chemical Information and Modeling

Untangling Amyloid-β, Tau, and Metals in Alzheimer’s Disease

(2013) Masha G. Savelieff et al.   ACS Chemical Biology

Total isoflavones from soybean and tempeh reversed scopolamine-induced amnesia, improved cholinergic activities and reduced neuroinflammation in brain

(2013) Aliya Ahmad et al.   FOOD AND CHEMICAL TOXICOLOGY

Target- and Mechanism-Based Therapeutics for Neurodegenerative Diseases: Strength in Numbers

(2013) Paul C. Trippier et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anti-inflammatory and redox-protective activities of citronellal

(2012) Mônica S Melo et al.   BIOLOGICAL RESEARCH

Acetylcholinesterase inhibitors: a patent review (2008 – present)

(2012) Miroslav Pohanka   EXPERT OPINION ON THERAPEUTIC PATENTS

Cholinergic therapy in dementia

(2010) P. J. Whitehouse   ACTA NEUROLOGICA SCANDINAVICA

Antinociceptive effect of citronellal in mice

(2010) M.S. Melo et al.   PHARMACEUTICAL BIOLOGY

Comparison of ginsenosides Rg1 and Rb1 for their effects on improving scopolamine-induced learning and memory impairment in mice

(2010) Qiong Wang et al.   PHYTOTHERAPY RESEARCH

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Amyloid-cholinesterase interactions

(2008) Nibaldo C. Inestrosa et al.   FEBS Journal

Plant-derived compounds in clinical trials

(2007) A SAKLANI et al.   DRUG DISCOVERY TODAY