Regulation of major bacterial survival strategies by transcripts sequestration in a membraneless organelle

Bacterial division ring stabilizing ZapA versus destabilizing SlmA modulate FtsZ switching between biomolecular condensates and polymers

(2023) Begoña Monterroso et al.   Open Biology

σ28-dependent small RNA regulation of flagella biosynthesis

(2023) Sahar Melamed et al.   eLife

ATP-responsive biomolecular condensates tune bacterial kinase signaling

(2022) Saumya Saurabh et al.   Science Advances

Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins

(2022) Amy J. Tibbo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A conceptual framework for understanding phase separation and addressing open questions and challenges

(2022) Tanja Mittag et al.   MOLECULAR CELL

The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems

(2022) Keren Lasker et al.   Nature Communications

Heterotypic phase separation of Hfq is linked to its roles as an RNA chaperone

(2022) Omer Goldberger et al.   Cell Reports

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

(2021) Simon Alberti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Liquid–liquid phase separation of tau: From molecular biophysics to physiology and disease

(2021) Sandeep K. Rai et al.   PROTEIN SCIENCE

It’s not just a phase: function and characteristics of RNA-binding proteins in phase separation

(2021) Hannah J. Wiedner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Prion-Like Proteins in Phase Separation and Their Link to Disease

(2021) Macy L. Sprunger et al.   Biomolecules

Liquid-liquid phase separation as a common organizing principle of intracellular space and biomembranes providing dynamic adaptive responses

(2021) Semen V. Nesterov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phase separation provides a mechanism to reduce noise in cells

(2020) A. Klosin et al.   SCIENCE

Protein Activity Sensing in Bacteria in Regulating Metabolism and Motility

(2020) Alejandra Alvarado et al.   Frontiers in Microbiology

Selective sequestration of signalling proteins in a membraneless organelle reinforces the spatial regulation of asymmetry in Caulobacter crescentus

(2020) Keren Lasker et al.   Nature Microbiology

ATP-Driven Separation of Liquid Phase Condensates in Bacteria

(2020) Baptiste Guilhas et al.   MOLECULAR CELL

RNA Granules: A View from the RNA Perspective

(2020) Siran Tian et al.   MOLECULES

Clusters of bacterial RNA polymerase are biomolecular condensates that assemble through liquid–liquid phase separation

(2020) Anne-Marie Ladouceur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecules involved in motility regulation in Escherichia coli cells: a review

(2020) Fazlurrahman Khan et al.   BIOFOULING

The emergence of phase separation as an organizing principle in bacteria

(2020) Christopher A. Azaldegui et al.   BIOPHYSICAL JOURNAL

RNA localization in prokaryotes: Where, when, how, and why

(2020) Mikel Irastortza‐Olaziregi et al.   Wiley Interdisciplinary Reviews-RNA

Phase Separation as a Missing Mechanism for Interpretation of Disease Mutations

(2020) Brian Tsang et al.   CELL

Tyrosine phosphorylation-dependent localization of TmaR that controls activity of a major bacterial sugar regulator by polar sequestration

(2020) Tamar Szoke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Phase separation and clustering of an ABC transporter in Mycobacterium tuberculosis

(2019) Florian Heinkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liquid–Liquid Phase Separation in Disease

(2019) Simon Alberti et al.   Annual Review of Genetics

Spatiotemporal Organization of the E. coli Transcriptome: Translation Independence and Engagement in Regulation

(2019) Shanmugapriya Kannaiah et al.   MOLECULAR CELL

Biomolecular condensates in neurodegeneration and cancer

(2019) Stephanie Spannl et al.   TRAFFIC

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

Biofilm Formation Plays a Role in the Formation of Multidrug-Resistant Escherichia coli Toward Nutrients in Microcosm Experiments

(2018) Xiu P. Chen et al.   Frontiers in Microbiology

Phenotypic Heterogeneity in Sugar Utilization by E. coli Is Generated by Stochastic Dispersal of the General PTS Protein EI from Polar Clusters

(2018) Sutharsan Govindarajan et al.   Frontiers in Microbiology

A New Lens for RNA Localization: Liquid-Liquid Phase Separation

(2018) Erin M. Langdon et al.   Annual Review of Microbiology

α-Proteobacterial RNA Degradosomes Assemble Liquid-Liquid Phase-Separated RNP Bodies

(2018) Nadra Al-Husini et al.   MOLECULAR CELL

Bacterial FtsZ protein forms phase‐separated condensates with its nucleoid‐associated inhibitor SlmA

(2018) Begoña Monterroso et al.   EMBO REPORTS

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Where are things inside a bacterial cell?

(2016) Sutharsan Govindarajan et al.   CURRENT OPINION IN MICROBIOLOGY

BindUP: a web server for non-homology-based prediction of DNA and RNA binding proteins

(2016) Inbal Paz et al.   NUCLEIC ACIDS RESEARCH

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Simultaneous generation of many RNA-seq libraries in a single reaction

(2015) Alexander A Shishkin et al.   NATURE METHODS

Membrane Recognition and Dynamics of the RNA Degradosome

(2015) Henrik Strahl et al.   PLoS Genetics

Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance

(2014) Jakob Domert et al.   NEUROBIOLOGY OF DISEASE

A novel single-cell screening platform reveals proteome plasticity during yeast stress responses

(2013) Michal Breker et al.   JOURNAL OF CELL BIOLOGY

High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states

(2013) Ronnie Blecher-Gonen et al.   Nature Protocols

Positive and negative selection using the tetA-sacB cassette: recombineering and P1 transduction in Escherichia coli

(2013) Xin-tian Li et al.   NUCLEIC ACIDS RESEARCH

Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells

(2012) Somenath Bakshi et al.   MOLECULAR MICROBIOLOGY

Chemotactic signaling via carbohydrate phosphotransferase systems inEscherichia coli

(2012) Silke Neumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Fail-Safe Mechanism in the Septal Ring Assembly Pathway Generated by the Sequential Recruitment of Cell Separation Amidases and Their Activators

(2011) N. T. Peters et al.   JOURNAL OF BACTERIOLOGY

Translation-Independent Localization of mRNA in E. coli

(2011) K. Nevo-Dinur et al.   SCIENCE

Conversion of a yeast prion protein to an infectious form in bacteria

(2010) S. J. Garrity et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

(2010) Y. Taniguchi et al.   SCIENCE

Protein Subcellular Localization in Bacteria

(2010) D. Z. Rudner et al.   Cold Spring Harbor Perspectives in Biology

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Global Analysis of Extracytoplasmic Stress Signaling in Escherichia coli

(2009) Stéphanie Bury-Moné et al.   PLoS Genetics