Heterotypic phase separation of Hfq is linked to its roles as an RNA chaperone

FuzDrop on AlphaFold: visualizing the sequence-dependent propensity of liquid–liquid phase separation and aggregation of proteins

(2022) Andras Hatos et al.   NUCLEIC ACIDS RESEARCH

RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment

(2021) Pallabi Basu et al.   Nature Communications

The association between Hfq and RNase E in long‐term nitrogen‐starved Escherichia coli

(2021) Josh McQuail et al.   MOLECULAR MICROBIOLOGY

RNA promotes the formation of spatial compartments in the nucleus

(2021) Sofia A. Quinodoz et al.   CELL

RNA sequence and structure control assembly and function of RNA condensates

(2021) Raghav R. Poudyal et al.   RNA

Liquid-Liquid Phase Separation: Unraveling the Enigma of Biomolecular Condensates in Microbial Cells

(2021) Zixu Gao et al.   Frontiers in Microbiology

Polyphosphate drives bacterial heterochromatin formation

(2021) Francois Beaufay et al.   Science Advances

Wisdom of the crowds: A suggested polygenic plan for small-RNA-mediated regulation in bacteria

(2021) Omer Goldberger et al.   iScience

RNA Droplets

(2020) Kevin Rhine et al.   Annual Review of Biophysics

Selective sequestration of signalling proteins in a membraneless organelle reinforces the spatial regulation of asymmetry in Caulobacter crescentus

(2020) Keren Lasker et al.   Nature Microbiology

Making the Case for Disordered Proteins and Biomolecular Condensates in Bacteria

(2020) Megan C. Cohan et al.   TRENDS IN BIOCHEMICAL SCIENCES

The RNA-binding protein Hfq assembles into foci-like structures in nitrogen starved Escherichia coli

(2020) Josh McQuail et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA contributions to the form and function of biomolecular condensates

(2020) Christine Roden et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA-Binding Proteins Driving the Regulatory Activity of Small Non-coding RNAs in Bacteria

(2020) Ana P. Quendera et al.   Frontiers in Molecular Biosciences

Tyrosine phosphorylation-dependent localization of TmaR that controls activity of a major bacterial sugar regulator by polar sequestration

(2020) Tamar Szoke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obstacles to Scanning by RNase E Govern Bacterial mRNA Lifetimes by Hindering Access to Distal Cleavage Sites

(2019) Jamie Richards et al.   MOLECULAR CELL

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

New molecular interactions broaden the functions of the RNA chaperone Hfq

(2019) Ricardo F. dos Santos et al.   CURRENT GENETICS

Spatiotemporal Organization of the E. coli Transcriptome: Translation Independence and Engagement in Regulation

(2019) Shanmugapriya Kannaiah et al.   MOLECULAR CELL

Identification of protein-protein and ribonucleoprotein complexes containing Hfq

(2019) Joël Caillet et al.   Scientific Reports

Global Maps of ProQ Binding In Vivo Reveal Target Recognition via RNA Structure and Stability Control at mRNA 3′ Ends

(2018) Erik Holmqvist et al.   MOLECULAR CELL

Imaging dynamic and selective low-complexity domain interactions that control gene transcription

(2018) Shasha Chong et al.   SCIENCE

A New Lens for RNA Localization: Liquid-Liquid Phase Separation

(2018) Erin M. Langdon et al.   Annual Review of Microbiology

α-Proteobacterial RNA Degradosomes Assemble Liquid-Liquid Phase-Separated RNP Bodies

(2018) Nadra Al-Husini et al.   MOLECULAR CELL

Protein aggregates encode epigenetic memory of stressful encounters in individual Escherichia coli cells

(2018) Sander K. Govers et al.   PLOS BIOLOGY

Bacterial FtsZ protein forms phase‐separated condensates with its nucleoid‐associated inhibitor SlmA

(2018) Begoña Monterroso et al.   EMBO REPORTS

Tail-Anchored Inner Membrane Protein ElaB Increases Resistance to Stress While Reducing Persistence in Escherichia coli

(2017) Yunxue Guo et al.   JOURNAL OF BACTERIOLOGY

Analysis of the natively unstructured RNA/protein-recognition core in the Escherichia coli RNA degradosome and its interactions with regulatory RNA/Hfq complexes

(2017) Heather A Bruce et al.   NUCLEIC ACIDS RESEARCH

Structural and dynamic properties of the C-terminal region of the Escherichia coli RNA chaperone Hfq: integrative experimental and computational studies

(2017) Bin Wen et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq

(2017) Eike C. Schulz et al.   Scientific Reports

Global Mapping of Small RNA-Target Interactions in Bacteria

(2016) Sahar Melamed et al.   MOLECULAR CELL

New insight into the structure and function of Hfq C-terminus

(2015) Emilie Fortas et al.   BIOSCIENCE REPORTS

Alternative Hfq-sRNA interaction modes dictate alternative mRNA recognition

(2015) D. J. Schu et al.   EMBO JOURNAL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Membrane Recognition and Dynamics of the RNA Degradosome

(2015) Henrik Strahl et al.   PLoS Genetics

PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition

(2014) A. K. Lancaster et al.   BIOINFORMATICS

TheEscherichia coliRNA processing and degradation machinery is compartmentalized within an organized cellular network

(2013) Aziz Taghbalout et al.   BIOCHEMICAL JOURNAL

The Bacterial Cytoplasm Has Glass-like Properties and Is Fluidized by Metabolic Activity

(2013) Bradley R. Parry et al.   CELL

Physiological Consequences of Multiple-Target Regulation by the Small RNA SgrS in Escherichia coli

(2013) Y. Sun et al.   JOURNAL OF BACTERIOLOGY

Mutations in Interaction Surfaces Differentially Impact E. coli Hfq Association with Small RNAs and Their mRNA Targets

(2013) Aixia Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Global Dynamics of the Escherichia coli Proteome and Phosphoproteome During Growth in Minimal Medium

(2013) Nelson C. Soares et al.   JOURNAL OF PROTEOME RESEARCH

Positive and negative selection using the tetA-sacB cassette: recombineering and P1 transduction in Escherichia coli

(2013) Xin-tian Li et al.   NUCLEIC ACIDS RESEARCH

Isolation and identification of new inner membrane-associated proteins that localize to cell poles inEscherichia coli

(2012) Gang Li et al.   MOLECULAR MICROBIOLOGY

RelA protein stimulates the activity of RyhB small RNA by acting on RNA-binding protein Hfq

(2012) L. Argaman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition

(2012) E. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo design of synthetic prion domains

(2012) J. A. Toombs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hfq and Hfq-dependent small RNAs are major contributors to multicellular development inSalmonella entericaserovar Typhimurium

(2012) Claudia Monteiro et al.   RNA Biology

Regulation by Small RNAs in Bacteria: Expanding Frontiers

(2011) Gisela Storz et al.   MOLECULAR CELL

Hfq and its constellation of RNA

(2011) Jörg Vogel et al.   NATURE REVIEWS MICROBIOLOGY

Translation-Independent Localization of mRNA in E. coli

(2011) K. Nevo-Dinur et al.   SCIENCE

The Response Regulator SprE (RssB) Is Required for Maintaining Poly(A) Polymerase I-Degradosome Association during Stationary Phase

(2010) V. J. Carabetta et al.   JOURNAL OF BACTERIOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS