The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems
出版年份 2022 全文链接
标题
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems
作者
关键词
-
出版物
Nature Communications
Volume 13, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-09-26
DOI
10.1038/s41467-022-33221-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Designer Condensates: A Toolkit for the Biomolecular Architect
- (2021) Renee L. Hastings et al. JOURNAL OF MOLECULAR BIOLOGY
- Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
- (2021) Simon Alberti et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phase Separation in Genome Organization across Evolution
- (2021) Marina Feric et al. TRENDS IN CELL BIOLOGY
- A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation
- (2021) Yanniv Dorone et al. CELL
- Clustering of Aromatic Residues in Prion-like Domains Can Tune the Formation, State, and Organization of Biomolecular Condensates
- (2021) Alex S. Holehouse et al. BIOCHEMISTRY
- Synthetic biomolecular condensates to engineer eukaryotic cells
- (2021) Christopher D. Reinkemeier et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Selective sequestration of signalling proteins in a membraneless organelle reinforces the spatial regulation of asymmetry in Caulobacter crescentus
- (2020) Keren Lasker et al. Nature Microbiology
- Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography
- (2020) Felix R. Wagner et al. Nature Protocols
- Making the Case for Disordered Proteins and Biomolecular Condensates in Bacteria
- (2020) Megan C. Cohan et al. TRENDS IN BIOCHEMICAL SCIENCES
- The In Situ Structure of Parkinson’s Disease-Linked LRRK2
- (2020) Reika Watanabe et al. CELL
- Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis
- (2020) Wei Li et al. NATURE CELL BIOLOGY
- Cryogenic single-molecule fluorescence annotations for electron tomography reveal in situ organization of key proteins in Caulobacter
- (2020) Peter D. Dahlberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intrinsically disordered bacterial polar organizing protein Z, PopZ, interacts with protein binding partners through an N-terminal Molecular Recognition Feature
- (2020) Christopher T. Nordyke et al. JOURNAL OF MOLECULAR BIOLOGY
- Beyond aggregation: Pathological phase transitions in neurodegenerative disease
- (2020) Cécile Mathieu et al. SCIENCE
- Protein Phase Separation as a Stress Survival Strategy
- (2019) Titus M. Franzmann et al. Cold Spring Harbor Perspectives in Biology
- NetSurfP-2.0: Improved prediction of protein structural features by integrated deep learning
- (2019) Michael Schantz Klausen et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
- (2019) Jacob R. Mann et al. NEURON
- Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly
- (2019) Sreejith J. Nair et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cellular sensing by phase separation: Using the process, not just the products
- (2019) Haneul Yoo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Software tools for automated transmission electron microscopy
- (2019) Martin Schorb et al. NATURE METHODS
- Why do eukaryotic proteins contain more intrinsically disordered regions?
- (2019) Walter Basile et al. PLoS Computational Biology
- Liquid–Liquid Phase Separation in Disease
- (2019) Simon Alberti et al. Annual Review of Genetics
- Controlling the material properties and rRNA processing function of the nucleolus using light
- (2019) Lian Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics
- (2019) Charlotte S. Sørensen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Probing and engineering liquid-phase organelles
- (2019) Dan Bracha et al. NATURE BIOTECHNOLOGY
- Phosphorylation Leads the Way for Protein Aggregate Disassembly
- (2018) Steven Boeynaems et al. DEVELOPMENTAL CELL
- Prions, prionoids and protein misfolding disorders
- (2018) Claudia Scheckel et al. NATURE REVIEWS GENETICS
- RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration
- (2018) Baskar Bakthavachalu et al. NEURON
- Phase separation of a yeast prion protein promotes cellular fitness
- (2018) Titus M. Franzmann et al. SCIENCE
- Protein Phase Separation: A New Phase in Cell Biology
- (2018) Steven Boeynaems et al. TRENDS IN CELL BIOLOGY
- Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
- (2018) Leeanne McGurk et al. MOLECULAR CELL
- Automated tilt series alignment and tomographic reconstruction in IMOD
- (2017) David N. Mastronarde et al. JOURNAL OF STRUCTURAL BIOLOGY
- Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging
- (2017) Wim J.H. Hagen et al. JOURNAL OF STRUCTURAL BIOLOGY
- Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
- (2017) Steven Boeynaems et al. MOLECULAR CELL
- Reversible protein aggregation is a protective mechanism to ensure cell cycle restart after stress
- (2017) Shady Saad et al. NATURE CELL BIOLOGY
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Liquid phase condensation in cell physiology and disease
- (2017) Yongdae Shin et al. SCIENCE
- An intracellular compass spatially coordinates cell cycle modules in Caulobacter crescentus
- (2016) Keren Lasker et al. CURRENT OPINION IN MICROBIOLOGY
- Sequence Determinants of the Conformational Properties of an Intrinsically Disordered Protein Prior to and upon Multisite Phosphorylation
- (2016) Erik W. Martin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- CaulobacterPopZ forms an intrinsically disordered hub in organizing bacterial cell poles
- (2016) Joshua A. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicrobeJ, a tool for high throughput bacterial cell detection and quantitative analysis
- (2016) Adrien Ducret et al. Nature Microbiology
- MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories
- (2015) Robert T. McGibbon et al. BIOPHYSICAL JOURNAL
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- JPred4: a protein secondary structure prediction server
- (2015) Alexey Drozdetskiy et al. NUCLEIC ACIDS RESEARCH
- Liquid-Liquid Phase Separation in Biology
- (2014) Anthony A. Hyman et al. Annual Review of Cell and Developmental Biology
- Classification of Intrinsically Disordered Regions and Proteins
- (2014) Robin van der Lee et al. CHEMICAL REVIEWS
- Robust membrane detection based on tensor voting for electron tomography
- (2014) Antonio Martinez-Sanchez et al. JOURNAL OF STRUCTURAL BIOLOGY
- ACaulobacter MreB mutant with irregular cell shape exhibits compensatory widening to maintain a preferred surface area to volume ratio
- (2014) Leigh K. Harris et al. MOLECULAR MICROBIOLOGY
- Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders
- (2013) Mani Ramaswami et al. CELL
- Oligomerization and higher-order assembly contribute to sub-cellular localization of a bacterial scaffold
- (2013) Grant R. Bowman et al. MOLECULAR MICROBIOLOGY
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues
- (2013) R. K. Das et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Branched Signal Wiring of an Essential Bacterial Cell-Cycle Phosphotransfer Protein
- (2013) Jimmy A. Blair et al. STRUCTURE
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- Crystal lattice properties fully determine short-range interaction parameters for alkali and halide ions
- (2012) Albert H. Mao et al. JOURNAL OF CHEMICAL PHYSICS
- Dynamo: A flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments
- (2012) Daniel Castaño-Díez et al. JOURNAL OF STRUCTURAL BIOLOGY
- Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy
- (2012) H. Hofmann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in the nucleotide binding pocket of MreB can alter cell curvature and polar morphology in Caulobacter
- (2011) Natalie A. Dye et al. MOLECULAR MICROBIOLOGY
- TDP-43 and FUS: a nuclear affair
- (2011) Dorothee Dormann et al. TRENDS IN NEUROSCIENCES
- A Cell-Type-Specific Protein-Protein Interaction Modulates Transcriptional Activity of a Master Regulator in Caulobacter crescentus
- (2010) Kasia G. Gora et al. MOLECULAR CELL
- CaulobacterPopZ forms a polar subdomain dictating sequential changes in pole composition and function
- (2010) Grant R. Bowman et al. MOLECULAR MICROBIOLOGY
- Cell mechanics and the cytoskeleton
- (2010) Daniel A. Fletcher et al. NATURE
- Net charge per residue modulates conformational ensembles of intrinsically disordered proteins
- (2010) A. H. Mao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation
- (2010) M. H. Tan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Charge interactions can dominate the dimensions of intrinsically disordered proteins
- (2010) S. Muller-Spath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enzymatic assembly of DNA molecules up to several hundred kilobases
- (2009) Daniel G Gibson et al. NATURE METHODS
- A Polymeric Protein Anchors the Chromosomal Origin/ParB Complex at a Bacterial Cell Pole
- (2008) Grant R. Bowman et al. CELL
- A Self-Associating Protein Critical for Chromosome Attachment, Division, and Polar Organization in Caulobacter
- (2008) Gitte Ebersbach et al. CELL
- ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions
- (2008) Andreas Vitalis et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started