Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins

Cyclic nucleotide signaling and pacemaker activity

(2021) Delphine Mika et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

PET imaging of phosphodiesterase-4 identifies affected dysplastic bone in McCune-Albright syndrome, a genetic mosaic disorder

(2020) Lora Deuitch Weidner et al.   JOURNAL OF NUCLEAR MEDICINE

POPDC2 a novel susceptibility gene for conduction disorders

(2020) Susanne Rinné et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Two Japanese LGMDR25 patients with a biallelic recurrent nonsense variant of BVES

(2020) Luh Ari Indrawati et al.   NEUROMUSCULAR DISORDERS

An interaction of heart disease-associated proteins POPDC1/2 with XIRP1 in transverse tubules and intercalated discs

(2020) Ian Holt et al.   BMC Molecular and Cell Biology

Therapeutic targeting of 3′,5′-cyclic nucleotide phosphodiesterases: inhibition and beyond

(2019) George S. Baillie et al.   NATURE REVIEWS DRUG DISCOVERY

POPDC3 Gene Variants Associate with a New Form of Limb Girdle Muscular Dystrophy

(2019) John Vissing et al.   ANNALS OF NEUROLOGY

Basal Spontaneous Firing of Rabbit Sinoatrial Node Cells Is Regulated by Dual Activation of PDEs (Phosphodiesterases) 3 and 4

(2018) Tatiana M. Vinogradova et al.   Circulation-Arrhythmia and Electrophysiology

Mapping the in vitro interactome of cardiac sodium (Na+ )-calcium (Ca2+ ) exchanger 1 (NCX1)

(2017) Tandekile Lubelwana Hafver et al.   PROTEOMICS

Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners

(2016) Kirsty F. Houslay et al.   BIOCHEMICAL JOURNAL

Location, location, location: PDE4D5 function is directed by its unique N-terminal region

(2016) Lauren Wills et al.   CELLULAR SIGNALLING

Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures

(2016) Xinchen Wang et al.   eLife

Two‐Pore K+Channel TREK‐1 Regulates Sinoatrial Node Membrane Excitability

(2016) Sathya D. Unudurthi et al.   Journal of the American Heart Association

Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy

(2015) Yuan Sin et al.   Cell Communication and Signaling

Phosphodiesterase4D (PDE4D) — A risk factor for atrial fibrillation and stroke?

(2015) Carina Jørgensen et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Burst pacemaker activity of the sinoatrial node in sodium–calcium exchanger knockout mice

(2015) Angelo G. Torrente et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterozygous mutations in cyclic AMP phosphodiesterase-4D (PDE4D) and protein kinase A (PKA) provide new insights into the molecular pathology of acrodysostosis

(2014) Tadashi Kaname et al.   CELLULAR SIGNALLING

Advances in targeting cyclic nucleotide phosphodiesterases

(2014) Donald H. Maurice et al.   NATURE REVIEWS DRUG DISCOVERY

The potassium current carried by TREK-1 channels in rat cardiac ventricular muscle

(2014) Mandy Bodnár et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Differential regulation of cardiac excitation–contraction coupling by cAMP phosphodiesterase subtypes

(2013) Delphine Mika et al.   CARDIOVASCULAR RESEARCH

Weighted Gene Coexpression Network Analysis of Human Left Atrial Tissue Identifies Gene Modules Associated With Atrial Fibrillation

(2013) Nicholas Tan et al.   Circulation-Cardiovascular Genetics

Bves and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition

(2013) Emily C. Benesh et al.   MOLECULAR BIOLOGY OF THE CELL

Popeye Domain Containing 1 (Popdc1/Bves) Is a Caveolae-Associated Protein Involved in Ischemia Tolerance

(2013) Yifat Alcalay et al.   PLoS One

Phosphodiesterase-8A binds to and regulates Raf-1 kinase

(2013) K. M. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

(2012) Patricia Neco et al.   CIRCULATION

The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development

(2012) Bettina C. Kirchmaier et al.   DEVELOPMENTAL BIOLOGY

Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice

(2012) Alexander Froese et al.   JOURNAL OF CLINICAL INVESTIGATION

Profiling of cAMP and cGMP phosphodiesterases in isolated ventricular cardiomyocytes from human hearts: Comparison with rat and guinea pig

(2012) W.B. Johnson et al.   LIFE SCIENCES

Distinct Patterns of Constitutive Phosphodiesterase Activity in Mouse Sinoatrial Node and Atrial Myocardium

(2012) Rui Hua et al.   PLoS One

The nuclear envelope proteome differs notably between tissues

(2012) Nadia Korfali et al.   Nucleus

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)–HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes

(2011) Y.Y. Sin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Conserved expression and functions of PDE4 in rodent and human heart

(2010) Wito Richter et al.   BASIC RESEARCH IN CARDIOLOGY

A Complex between FAK, RACK1, and PDE4D5 Controls Spreading Initiation and Cancer Cell Polarity

(2010) Bryan Serrels et al.   CURRENT BIOLOGY

Identification of a novel Bves function: regulation of vesicular transport

(2010) Hillary A Hager et al.   EMBO JOURNAL

Several Novel Nuclear Envelope Transmembrane Proteins Identified in Skeletal Muscle Have Cytoskeletal Associations

(2010) Gavin S. Wilkie et al.   MOLECULAR & CELLULAR PROTEOMICS

Genesis and Regulation of the Heart Automaticity

(2008) Matteo E. Mangoni et al.   PHYSIOLOGICAL REVIEWS

Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity

(2008) T. K. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA