Altered brain serotonin 5-HT1A receptor expression and function in juvenile Fmr1 knockout mice

Antisense oligonucleotide rescue of CGG expansion–dependent FMR1 mis-splicing in fragile X syndrome restores FMRP

(2023) Sneha Shah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seizures in Fragile X Syndrome: Associations and Longitudinal Analysis of a Large Clinic-Based Cohort

(2022) Elizabeth Berry-Kravis et al.   Frontiers in Pediatrics

Targeting 5‐HT1A Receptors to Correct Neuronal Hyperexcitability in Fmr1 Knockout Mice

(2022) Tanishka S. Saraf et al.   FASEB JOURNAL

The Role of 5-HT1A Receptors and Neuronal Nitric Oxide Synthase in a Seizur Induced Kindling Model in Rats

(2022) Zinat Heydarnia Kalati et al.   NEUROCHEMICAL RESEARCH

FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT1A, 5-HT1B, and 5-HT1D Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Fmr1 Knockout Mice

(2022) Tanishka S. Saraf et al.   ACS Chemical Neuroscience

Hemispheric Utilization of Alpha Oscillatory Dynamics as a Unique Biomarker of Neural Compensation in Females with Fragile X Syndrome

(2022) Jordan E. Norris et al.   ACS Chemical Neuroscience

Acute and Repeated Administration of NLX-101, a Selective Serotonin-1A Receptor Biased Agonist, Reduces Audiogenic Seizures in Developing Fmr1 Knockout Mice

(2022) X. Tao et al.   NEUROSCIENCE

Increasing the statistical power of animal experiments with historical control data

(2021) V. Bonapersona et al.   NATURE NEUROSCIENCE

The molecular biology of FMRP: new insights into fragile X syndrome

(2021) Joel D. Richter et al.   NATURE REVIEWS NEUROSCIENCE

Inhibition of phosphodiesterase-4D in adults with fragile X syndrome: a randomized, placebo-controlled, phase 2 clinical trial

(2021) Elizabeth M. Berry-Kravis et al.   NATURE MEDICINE

Channelopathies in fragile X syndrome

(2021) Pan-Yue Deng et al.   NATURE REVIEWS NEUROSCIENCE

Evaluation of lorcaserin as an anticonvulsant in juvenile Fmr1 knockout mice

(2021) Tanishka S. Saraf et al.   EPILEPSY RESEARCH

A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies

(2021) Yunhee Kang et al.   NATURE NEUROSCIENCE

Translating biased agonists from molecules to medications: Serotonin 5-HT1A receptor functional selectivity for CNS disorders

(2021) Adrian Newman-Tancredi et al.   PHARMACOLOGY & THERAPEUTICS

Neural Correlates of Auditory Hypersensitivity in Fragile X Syndrome

(2021) Khaleel A. Razak et al.   Frontiers in Psychiatry

Auditory cortex shapes sound responses in the inferior colliculus

(2020) Jennifer M Blackwell et al.   eLife

International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

(2020) Nicholas M. Barnes et al.   PHARMACOLOGICAL REVIEWS

Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome

(2019) Jonathan W Lovelace et al.   CEREBRAL CORTEX

Audiogenic Seizures in the Fmr1 Knock-Out Mouse Are Induced by Fmr1 Deletion in Subcortical, VGlut2-Expressing Excitatory Neurons and Require Deletion in the Inferior Colliculus

(2019) Darya Gonzalez et al.   JOURNAL OF NEUROSCIENCE

OUP accepted manuscript

(2018)   CEREBRAL CORTEX

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome

(2018) Jonathan W. Lovelace et al.   NEUROBIOLOGY OF DISEASE

Abnormal Sleep Architecture and Hippocampal Circuit Dysfunction in a Mouse Model of Fragile X Syndrome

(2018) Christine E. Boone et al.   NEUROSCIENCE

Decreased surface expression of the δ subunit of the GABA A receptor contributes to reduced tonic inhibition in dentate granule cells in a mouse model of fragile X syndrome

(2017) Nianhui Zhang et al.   EXPERIMENTAL NEUROLOGY

Impaired GABAergic inhibition in the hippocampus of Fmr1 knockout mice

(2017) Victor Sabanov et al.   NEUROPHARMACOLOGY

Autism Spectrum Disorder in Fragile X Syndrome: Cooccurring Conditions and Current Treatment

(2017) Walter E. Kaufmann et al.   PEDIATRICS

Excitability is increased in hippocampal CA1 pyramidal cells of Fmr1 knockout mice

(2017) M. Angeles Luque et al.   PLoS One

Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice

(2017) Elisabetta Aloisi et al.   Nature Communications

Multiple Behavior Phenotypes of the Fragile-X Syndrome Mouse Model Respond to Chronic Inhibition of Phosphodiesterase-4D (PDE4D)

(2017) Mark E. Gurney et al.   Scientific Reports

Altered intrinsic properties and bursting activities of neurons in layer IV of somatosensory cortex from Fmr-1 knockout mice

(2016) Linming Zhang et al.   EXPERIMENTAL NEUROLOGY

Hippocampal dysfunction and cognitive impairment in Fragile-X Syndrome

(2016) Crystal Bostrom et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Increased Persistent Sodium Current Causes Neuronal Hyperexcitability in the Entorhinal Cortex of Fmr1 Knockout Mice

(2016) Pan-Yue Deng et al.   Cell Reports

Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models

(2016) Catherine H. Choi et al.   Frontiers in Behavioral Neuroscience

An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models

(2015) Clinton E. Canal et al.   ACS Chemical Neuroscience

GABABreceptor-mediated feed-forward circuit dysfunction in the mouse model of fragile X syndrome

(2015) Sarah Wahlstrom-Helgren et al.   JOURNAL OF PHYSIOLOGY-LONDON

Altered Neuronal and Circuit Excitability in Fragile X Syndrome

(2015) Anis Contractor et al.   NEURON

Sensitive and critical periods during neurotypical and aberrant neurodevelopment: A framework for neurodevelopmental disorders

(2015) R.M. Meredith   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1 −/y mice

(2014) Yu Zhang et al.   NATURE NEUROSCIENCE

Role of 5-HT1A- and 5-HT2A receptors for the murine model of the serotonin syndrome

(2014) Robert Haberzettl et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Animal models of the serotonin syndrome: A systematic review

(2013) Robert Haberzettl et al.   BEHAVIOURAL BRAIN RESEARCH

The translation of translational control by FMRP: therapeutic targets for FXS

(2013) Jennifer C Darnell et al.   NATURE NEUROSCIENCE

Neural Basis for the Ability of Atypical Antipsychotic Drugs to Improve Cognition in Schizophrenia

(2013) Tomiki Sumiyoshi et al.   Frontiers in Behavioral Neuroscience

Rethinking 5-HT1A Receptors: Emerging Modes of Inhibitory Feedback of Relevance to Emotion-Related Behavior

(2012) Stefanie C. Altieri et al.   ACS Chemical Neuroscience

Learning and Memory Deficits Consequent to Reduction of the Fragile X Mental Retardation Protein Result from Metabotropic Glutamate Receptor-Mediated Inhibition of cAMP Signaling in Drosophila

(2012) A. K. Kanellopoulos et al.   JOURNAL OF NEUROSCIENCE

Sensitive time-windows for susceptibility in neurodevelopmental disorders

(2012) Rhiannon M. Meredith et al.   TRENDS IN NEUROSCIENCES

5-HT1A Receptor Agonists Enhance Pyramidal Cell Firing in Prefrontal Cortex Through a Preferential Action on GABA Interneurons

(2011) L. Llado-Pelfort et al.   CEREBRAL CORTEX

Serotonergic regulation of neuronal excitability in the prefrontal cortex

(2011) Rodrigo Andrade   NEUROPHARMACOLOGY

A prospective open-label study of aripiprazole in fragile X syndrome

(2011) Craig A. Erickson et al.   PSYCHOPHARMACOLOGY

Aging in fragile X syndrome

(2010) Agustini Utari et al.   Journal of Neurodevelopmental Disorders

Critical Period Plasticity Is Disrupted in the Barrel Cortex of Fmr1 Knockout Mice

(2010) Emily G. Harlow et al.   NEURON

Early developmental alterations in GABAergic protein expression in fragile X knockout mice

(2010) Daniel C. Adusei et al.   NEUROPHARMACOLOGY

Aripiprazole in autism spectrum disorders and fragile X syndrome

(2010) Craig A. Erickson et al.   Neurotherapeutics

The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen

(2010) Clinton E. Canal et al.   PSYCHOPHARMACOLOGY

Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain

(2008) Laura Saenz del Burgo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome

(2008) Jay R. Gibson et al.   JOURNAL OF NEUROPHYSIOLOGY