Evaluation of lorcaserin as an anticonvulsant in juvenile Fmr1 knockout mice

New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome

(2020) Ettore Tiraboschi et al.   EPILEPSIA

Automated quantification of head-twitch response in mice via ear tag reporter coupled with biphasic detection

(2020) Mario de la Fuente Revenga et al.   JOURNAL OF NEUROSCIENCE METHODS

Psychedelic Psychiatry’s Brave New World

(2020) David Nutt et al.   CELL

A 5‐HT 1D ‐Receptor Agonist Protects Dravet Syndrome Mice from Seizure and Early Death

(2020) Paul G. Hatini et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species

(2020) Adam L. Halberstadt et al.   NEUROPHARMACOLOGY

Serotonin research: Crossing scales and boundaries

(2020) Giuseppe Di Giovanni et al.   NEUROPHARMACOLOGY

International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

(2020) Nicholas M. Barnes et al.   PHARMACOLOGICAL REVIEWS

The Synthetic Cathinone Psychostimulant α-PPP Antagonizes Serotonin 5-HT2A Receptors: In Vitro and In Vivo Evidence

(2019) Yiming Chen et al.   Drug Testing and Analysis

Evaluation of Selective 5-HT2C Agonists in Acute Seizure Models

(2019) Leonardo B. Silenieks et al.   ACS Chemical Neuroscience

M100907 and BD 1047 attenuate the acute toxic effects of methamphetamine

(2019) Azizi Ray et al.   NEUROTOXICOLOGY

A single early-life seizure results in long-term behavioral changes in the adult Fmr1 knockout mouse

(2019) Samantha L. Hodges et al.   EPILEPSY RESEARCH

Audiogenic Seizures in the Fmr1 Knock-Out Mouse Are Induced by Fmr1 Deletion in Subcortical, VGlut2-Expressing Excitatory Neurons and Require Deletion in the Inferior Colliculus

(2019) Darya Gonzalez et al.   JOURNAL OF NEUROSCIENCE

5-HT2 receptor activation alleviates airway inflammation and structural remodeling in a chronic mouse asthma model

(2019) Thomas W. Flanagan et al.   LIFE SCIENCES

Lorcaserin: A review of its preclinical and clinical pharmacology and therapeutic potential

(2019) Guy A. Higgins et al.   PHARMACOLOGY & THERAPEUTICS

The new definition and classification of seizures and epilepsy

(2018) Jessica J. Falco-Walter et al.   EPILEPSY RESEARCH

Nucleus of the Solitary Tract Serotonin 5-HT2C Receptors Modulate Food Intake

(2018) Giuseppe D'Agostino et al.   Cell Metabolism

Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible

(2018) Anubhuti Goel et al.   NATURE NEUROSCIENCE

Lorcaserin therapy for severe epilepsy of childhood onset

(2018) Patricia Tolete et al.   NEUROLOGY

Nighttime Sleep and Daytime Sleepiness Improved With Pimavanserin During Treatment of Parkinson’s Disease Psychosis

(2018) Neepa Patel et al.   CLINICAL NEUROPHARMACOLOGY

Developmental Changes in EEG Phenotypes in a Mouse Model of Fragile X Syndrome

(2018) Teresa H. Wen et al.   NEUROSCIENCE

Impaired GABAergic inhibition in the hippocampus of Fmr1 knockout mice

(2017) Victor Sabanov et al.   NEUROPHARMACOLOGY

Autism Spectrum Disorder in Fragile X Syndrome: Cooccurring Conditions and Current Treatment

(2017) Walter E. Kaufmann et al.   PEDIATRICS

A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment

(2017) Jose M. Palacios et al.   PSYCHOPHARMACOLOGY

Fragile X syndrome

(2017) Randi J. Hagerman et al.   Nature Reviews Disease Primers

Mutagenesis Analysis Reveals Distinct Amino Acids of the Human Serotonin 5-HT2C Receptor Underlying the Pharmacology of Distinct Ligands

(2016) Yue Liu et al.   ACS Chemical Neuroscience

Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model

(2016) Jo Sourbron et al.   ACS Chemical Neuroscience

Psychedelics as Medicines: An Emerging New Paradigm

(2016) DE Nichols et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Characterization of the discriminative stimulus effects of lorcaserin in rats

(2016) Katherine M. Serafine et al.   JOURNAL OF THE EXPERIMENTAL ANALYSIS OF BEHAVIOR

Role for serotonin2A (5-HT2A) and 2C (5-HT2C) receptors in experimental absence seizures

(2016) Marcello Venzi et al.   NEUROPHARMACOLOGY

An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models

(2015) Clinton E. Canal et al.   ACS Chemical Neuroscience

Serotonergic System and Its Role in Epilepsy and Neuropathic Pain Treatment: A Review Based on Receptor Ligands

(2015) Katarzyna Panczyk et al.   CURRENT PHARMACEUTICAL DESIGN

Mice Lacking the Serotonin Htr 2B Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype

(2015) Pothitos M Pitychoutis et al.   NEUROPSYCHOPHARMACOLOGY

Social Behavioral Deficits Coincide with the Onset of Seizure Susceptibility in Mice Lacking Serotonin Receptor 2c

(2015) Julien Séjourné et al.   PLoS One

Role(s) of the 5-HT2C Receptor in the Development of Maximal Dentate Activation in the Hippocampus of Anesthetized Rats

(2014) Gergely Orban et al.   CNS Neuroscience & Therapeutics

EEG abnormalities and seizures in genetically diagnosed Fragile X syndrome

(2014) Takijah T. Heard et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model

(2013) Clinton E. Canal et al.   NEUROPHARMACOLOGY

Characterization of the head-twitch response induced by hallucinogens in mice

(2013) Adam L. Halberstadt et al.   PSYCHOPHARMACOLOGY

Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model

(2012) Clint E. Canal et al.   Drug Testing and Analysis

Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease

(2012) Sylvia Navailles et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Evaluation of the Abuse Potential of Lorcaserin, a Serotonin 2C (5-HT2C) Receptor Agonist, in Recreational Polydrug Users

(2011) M J Shram et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Status epilepticus in fragile X syndrome

(2010) Magali Gauthey et al.   EPILEPSIA

Interaction of 5-HT2A and 5-HT2C Receptors in R(-)-2,5-Dimethoxy-4-iodoamphetamine-Elicited Head Twitch Behavior in Mice

(2010) W. E. Fantegrossi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Stimulation of serotonin2C receptors elicits abnormal oral movements by acting on pathways other than the sensorimotor one in the rat basal ganglia

(2010) A. Beyeler et al.   NEUROSCIENCE

The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen

(2010) Clinton E. Canal et al.   PSYCHOPHARMACOLOGY

5-HT2A and 5-HT2C Receptors Exert Opposing Effects on Locomotor Activity in Mice

(2009) Adam L Halberstadt et al.   NEUROPSYCHOPHARMACOLOGY

Origins of Epilepsy in Fragile X Syndrome

(2009) Paul J. Hagerman et al.   Epilepsy Currents

Co-occurring conditions associated withFMR1gene variations: Findings from a national parent survey

(2008) Donald B. Bailey et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Lorcaserin, a Novel Selective Human 5-Hydroxytryptamine2C Agonist: in Vitro and in Vivo Pharmacological Characterization

(2008) W. J. Thomsen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS