Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome

Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models

(2019) Michelle W. Antoine et al.   NEURON

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome

(2018) Jonathan W. Lovelace et al.   NEUROBIOLOGY OF DISEASE

Chronic minocycline treatment improves hippocampal neuronal structure, NMDA receptor function, and memory processing in Fmr1 knockout mice

(2018) S.Y. Yau et al.   NEUROBIOLOGY OF DISEASE

Sensory Processing Phenotypes in Fragile X Syndrome

(2018) Maham Rais et al.   ASN Neuro

Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible

(2018) Anubhuti Goel et al.   NATURE NEUROSCIENCE

The Perineuronal ‘Safety’ Net? Perineuronal Net Abnormalities in Neurological Disorders

(2018) Teresa H. Wen et al.   Frontiers in Molecular Neuroscience

A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome

(2017) Jun Wang et al.   Journal of Neurodevelopmental Disorders

Modeling fast and slow gamma oscillations with interneurons of different subtype

(2017) Stephen Keeley et al.   JOURNAL OF NEUROPHYSIOLOGY

Enhanced Excitatory Connectivity and Disturbed Sound Processing in the Auditory Brainstem of Fragile X Mice

(2017) Elisabet Garcia-Pino et al.   JOURNAL OF NEUROSCIENCE

Cortical gamma band synchronization through somatostatin interneurons

(2017) Julia Veit et al.   NATURE NEUROSCIENCE

Sensory processing in autism spectrum disorders and Fragile X syndrome—From the clinic to animal models

(2017) D. Sinclair et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome

(2017) Lauren E. Ethridge et al.   Molecular Autism

mTOR, a Potential Target to Treat Autism Spectrum Disorder

(2016) Atsushi Sato   CNS & Neurological Disorders-Drug Targets

Cellular distribution of the fragile X mental retardation protein in the mouse brain

(2016) Diego A.R. Zorio et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Removal of Perineuronal Nets Unlocks Juvenile Plasticity Through Network Mechanisms of Decreased Inhibition and Increased Gamma Activity

(2016) Kristian Kinden Lensjø et al.   JOURNAL OF NEUROSCIENCE

Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome

(2016) Jonathan W. Lovelace et al.   NEUROBIOLOGY OF DISEASE

Impaired cognitive discrimination and discoordination of coupled theta–gamma oscillations in Fmr1 knockout mice

(2016) Basma Radwan et al.   NEUROBIOLOGY OF DISEASE

Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism

(2016) Federica Filice et al.   Molecular Brain

Chondroitin 6-Sulfation Regulates Perineuronal Net Formation by Controlling the Stability of Aggrecan

(2016) Shinji Miyata et al.   NEURAL PLASTICITY

Reduced habituation of auditory evoked potentials indicate cortical hyper-excitability in Fragile X Syndrome

(2016) L E Ethridge et al.   Translational Psychiatry

Matrix Metalloproteinase-9 Regulates Neuronal Circuit Development and Excitability

(2015) Sachiko Murase et al.   MOLECULAR NEUROBIOLOGY

Altered Neuronal and Circuit Excitability in Fragile X Syndrome

(2015) Anis Contractor et al.   NEURON

The GABAA Receptor as a Therapeutic Target for Neurodevelopmental Disorders

(2015) Sien Braat et al.   NEURON

Independent role for presynaptic FMRP revealed by anFMR1missense mutation associated with intellectual disability and seizures

(2015) Leila K. Myrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A cortical disinhibitory circuit for enhancing adult plasticity

(2015) Yu Fu et al.   eLife

Deletion of Fmr1 Alters Function and Synaptic Inputs in the Auditory Brainstem

(2015) Sarah E. Rotschafer et al.   PLoS One

Genetic Removal of Matrix Metalloproteinase 9 Rescues the Symptoms of Fragile X Syndrome in a Mouse Model

(2014) H. Sidhu et al.   JOURNAL OF NEUROSCIENCE

Toward a proper estimation of phase–amplitude coupling in neural oscillations

(2014) Dino Dvorak et al.   JOURNAL OF NEUROSCIENCE METHODS

Distribution of fragile X mental retardation protein in the human auditory brainstem

(2014) K. Beebe et al.   NEUROSCIENCE

Rescue of fragile X syndrome phenotypes in Fmr1KO mice by a BKCa channel opener molecule

(2014) Betty Hébert et al.   Orphanet Journal of Rare Diseases

Auditory Processing in Fragile X Syndrome

(2014) Sarah E. Rotschafer et al.   Frontiers in Cellular Neuroscience

Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

(2014) Laurent Ferron et al.   Nature Communications

Pharmacogenetic Inhibition of eIF4E-Dependent Mmp9 mRNA Translation Reverses Fragile X Syndrome-like Phenotypes

(2014) Christos G. Gkogkas et al.   Cell Reports

High MMP-9 activity levels in fragile X syndrome are lowered by minocycline

(2013) Magdalena Dziembowska et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Altered auditory processing in a mouse model of fragile X syndrome

(2013) Sarah Rotschafer et al.   BRAIN RESEARCH

Intense and specialized dendritic localization of the fragile X mental retardation protein in binaural brainstem neurons: A comparative study in the alligator, chicken, gerbil, and human

(2013) Yuan Wang et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Integrin  3 Is Required for Late Postnatal Stability of Dendrite Arbors, Dendritic Spines and Synapses, and Mouse Behavior

(2013) M. E. Kerrisk et al.   JOURNAL OF NEUROSCIENCE

The Fragile X Mental Retardation Protein Regulates Matrix Metalloproteinase 9 mRNA at Synapses

(2013) A. Janusz et al.   JOURNAL OF NEUROSCIENCE

Impaired Critical Period Plasticity in Primary Auditory Cortex of Fragile X Model Mice

(2013) H. Kim et al.   JOURNAL OF NEUROSCIENCE

Parvalbumin-Expressing Inhibitory Interneurons in Auditory Cortex Are Well-Tuned for Frequency

(2013) A. K. Moore et al.   JOURNAL OF NEUROSCIENCE

Electrocortical changes associated with minocycline treatment in fragile X syndrome

(2013) Andrea Schneider et al.   JOURNAL OF PSYCHOPHARMACOLOGY

FMRP Regulates Neurotransmitter Release and Synaptic Information Transmission by Modulating Action Potential Duration via BK Channels

(2013) Pan-Yue Deng et al.   NEURON

Erbb4 Deletion from Fast-Spiking Interneurons Causes Schizophrenia-like Phenotypes

(2013) Isabel del Pino et al.   NEURON

Long-lasting effects of minocycline on behavior in young but not adult Fragile X mice

(2013) L.E. Dansie et al.   NEUROSCIENCE

Perineuronal nets protect fast-spiking interneurons against oxidative stress

(2013) J.-H. Cabungcal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X Syndrome

(2012) Sarah E. Rotschafer et al.   BRAIN RESEARCH

Development and Characterization of NEX-Pten,a Novel Forebrain Excitatory Neuron-Specific Knockout Mouse

(2012) Tatiana M. Kazdoba et al.   DEVELOPMENTAL NEUROSCIENCE

Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome

(2012) C. A. Hoeffer et al.   GENES BRAIN AND BEHAVIOR

Parvalbumin immunoreactivity in the auditory cortex of a mouse model of presbycusis

(2012) H.N. Martin del Campo et al.   HEARING RESEARCH

Aggrecan: Beyond cartilage and into the brain

(2012) M. Morawski et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MMP9: A novel function in synaptic plasticity

(2012) Magdalena Dziembowska et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of Neuronal Excitability by Interaction of Fragile X Mental Retardation Protein with Slack Potassium Channels

(2012) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

The Psychiatric Presentation of Fragile X: Evolution of the Diagnosis and Treatment of the Psychiatric Comorbidities of Fragile X Syndrome

(2011) Michael R. Tranfaglia   DEVELOPMENTAL NEUROSCIENCE

Fragile X Mental Retardation Protein Regulates Protein Expression and mRNA Translation of the Potassium Channel Kv4.2

(2011) C. Gross et al.   JOURNAL OF NEUROSCIENCE

Dense, Unspecific Connectivity of Neocortical Parvalbumin-Positive Interneurons: A Canonical Microcircuit for Inhibition?

(2011) A. M. Packer et al.   JOURNAL OF NEUROSCIENCE

Downregulation of Parvalbumin at Cortical GABA Synapses Reduces Network Gamma Oscillatory Activity

(2011) V. Volman et al.   JOURNAL OF NEUROSCIENCE

Altered Neocortical Rhythmic Activity States in Fmr1 KO Mice Are Due to Enhanced mGluR5 Signaling and Involve Changes in Excitatory Circuitry

(2011) S. A. Hays et al.   JOURNAL OF NEUROSCIENCE

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior

(2011) M Carlén et al.   MOLECULAR PSYCHIATRY

Different Origins of Gamma Rhythm and High-Gamma Activity in Macaque Visual Cortex

(2011) Supratim Ray et al.   PLOS BIOLOGY

mGluR5 in Cortical Excitatory Neurons Exerts Both Cell-Autonomous and -Nonautonomous Influences on Cortical Somatosensory Circuit Formation

(2010) C. J. Ballester-Rosado et al.   JOURNAL OF NEUROSCIENCE

Dysregulation of mTOR Signaling in Fragile X Syndrome

(2010) A. Sharma et al.   JOURNAL OF NEUROSCIENCE

Parvalbumin Deficiency and GABAergic Dysfunction in Mice Lacking PGC-1 

(2010) E. K. Lucas et al.   JOURNAL OF NEUROSCIENCE

Fragile X Mental Retardation Protein Is Required for Rapid Experience-Dependent Regulation of the Potassium Channel Kv3.1b

(2010) J. G. Strumbos et al.   JOURNAL OF NEUROSCIENCE

Physiological Activation of Synaptic Rac>PAK (p-21 Activated Kinase) Signaling Is Defective in a Mouse Model of Fragile X Syndrome

(2010) L. Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack

(2010) Maile R Brown et al.   NATURE NEUROSCIENCE

Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons

(2010) Michael C Chang et al.   NATURE NEUROSCIENCE

Aggrecan expression, a component of the inhibitory interneuron perineuronal net, is altered following an early-life seizure

(2010) Paulette A. McRae et al.   NEUROBIOLOGY OF DISEASE

Modulation of Visual Responses by Behavioral State in Mouse Visual Cortex

(2010) Cristopher M. Niell et al.   NEURON

Genetic and cell biological analysis of integrin outside-in signaling

(2009) K. R. Legate et al.   GENES & DEVELOPMENT

Pro-BDNF–induced synaptic depression and retraction at developing neuromuscular synapses

(2009) Feng Yang et al.   JOURNAL OF CELL BIOLOGY

The FXG: A Presynaptic Fragile X Granule Expressed in a Subset of Developing Brain Circuits

(2009) S. B. Christie et al.   JOURNAL OF NEUROSCIENCE

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

(2009) Jessica A. Cardin et al.   NATURE

Inhibitory Stabilization of the Cortical Network Underlies Visual Surround Suppression

(2009) Hirofumi Ozeki et al.   NEURON

Mouse auditory cortex differs from visual and somatosensory cortices in the laminar distribution of cytochrome oxidase and acetylcholinesterase

(2008) L.A. Anderson et al.   BRAIN RESEARCH

Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome

(2008) Jay R. Gibson et al.   JOURNAL OF NEUROPHYSIOLOGY

Spectrotemporal Processing Differences between Auditory Cortical Fast-Spiking and Regular-Spiking Neurons

(2008) C. A. Atencio et al.   JOURNAL OF NEUROSCIENCE

Homer Interactions Are Necessary for Metabotropic Glutamate Receptor-Induced Long-Term Depression and Translational Activation

(2008) J. A. Ronesi et al.   JOURNAL OF NEUROSCIENCE

GABA Neurons and the Mechanisms of Network Oscillations: Implications for Understanding Cortical Dysfunction in Schizophrenia

(2008) G. Gonzalez-Burgos et al.   SCHIZOPHRENIA BULLETIN

Chirp-evoked potentials in the awake and anesthetized rat. A procedure to assess changes in cortical oscillatory activity

(2007) M. Pérez-Alcázar et al.   EXPERIMENTAL NEUROLOGY