Acute and Repeated Administration of NLX-101, a Selective Serotonin-1A Receptor Biased Agonist, Reduces Audiogenic Seizures in Developing Fmr1 Knockout Mice

Translating biased agonists from molecules to medications: Serotonin 5-HT1A receptor functional selectivity for CNS disorders

(2021) Adrian Newman-Tancredi et al.   PHARMACOLOGY & THERAPEUTICS

Neural Correlates of Auditory Hypersensitivity in Fragile X Syndrome

(2021) Khaleel A. Razak et al.   Frontiers in Psychiatry

Abnormal development of auditory responses in the inferior colliculus of a mouse model of Fragile X Syndrome

(2020) Anna O. Nguyen et al.   JOURNAL OF NEUROPHYSIOLOGY

Amygdala lesions reduce seizure-induced respiratory arrest in DBA/1 mice

(2019) Anthony Marincovich et al.   EPILEPSY & BEHAVIOR

Audiogenic Seizures in the Fmr1 Knock-Out Mouse Are Induced by Fmr1 Deletion in Subcortical, VGlut2-Expressing Excitatory Neurons and Require Deletion in the Inferior Colliculus

(2019) Darya Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome

(2018) Jonathan W. Lovelace et al.   NEUROBIOLOGY OF DISEASE

Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model

(2018) Honghai Zhang et al.   NEUROBIOLOGY OF DISEASE

A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome

(2017) Jun Wang et al.   Journal of Neurodevelopmental Disorders

The effect of sertraline and 8-OH-DPAT on the PTZ_induced seizure threshold: Role of the nitrergic system

(2017) Azhdar Heydari et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

5-Hydroxytryptophan, a precursor for serotonin synthesis, reduces seizure-induced respiratory arrest

(2016) Honghai Zhang et al.   EPILEPSIA

A Randomized, Double-Blind, Placebo-Controlled Trial of Low-Dose Sertraline in Young Children With Fragile X Syndrome

(2016) Laura Greiss Hess et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Reduced habituation of auditory evoked potentials indicate cortical hyper-excitability in Fragile X Syndrome

(2016) L E Ethridge et al.   Translational Psychiatry

An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models

(2015) Clinton E. Canal et al.   ACS Chemical Neuroscience

Behavioral changes following a single episode of early-life seizures support the latent development of an autistic phenotype

(2015) Paul B. Bernard et al.   EPILEPSY & BEHAVIOR

Early life seizures: Evidence for chronic deficits linked to autism and intellectual disability across species and models

(2015) Paul B. Bernard et al.   EXPERIMENTAL NEUROLOGY

Serotonin neurones have anti-convulsant effects and reduce seizure-induced mortality

(2014) Gordon F. Buchanan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Altered auditory processing in a mouse model of fragile X syndrome

(2013) Sarah Rotschafer et al.   BRAIN RESEARCH

Long-lasting effects of minocycline on behavior in young but not adult Fragile X mice

(2013) L.E. Dansie et al.   NEUROSCIENCE

Biased agonism at serotonin 5-HT1A receptors: preferential postsynaptic activity for improved therapy of CNS disorders

(2012) Adrian Newman-Tancredi   Neuropsychiatry

5-HT1A Receptor Agonists Enhance Pyramidal Cell Firing in Prefrontal Cortex Through a Preferential Action on GABA Interneurons

(2011) L. Llado-Pelfort et al.   CEREBRAL CORTEX

Preferential in vivo action of F15599, a novel 5-HT1A receptor agonist, at postsynaptic 5-HT1A receptors

(2010) L Lladó-Pelfort et al.   BRITISH JOURNAL OF PHARMACOLOGY

Serotonin in the inferior colliculus fluctuates with behavioral state and environmental stimuli

(2010) I. C. Hall et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1Areceptor agonist

(2009) A Newman-Tancredi et al.   BRITISH JOURNAL OF PHARMACOLOGY