GABABreceptor-mediated feed-forward circuit dysfunction in the mouse model of fragile X syndrome

Independent role for presynaptic FMRP revealed by anFMR1missense mutation associated with intellectual disability and seizures

(2015) Leila K. Myrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activity-dependent regulation of release probability at excitatory hippocampal synapses: a crucial role of fragile X mental retardation protein in neurotransmission

(2014) Xiao-Sheng Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Deficient tonic GABAergic conductance and synaptic balance in the fragile X syndrome amygdala

(2014) Brandon S. Martin et al.   JOURNAL OF NEUROPHYSIOLOGY

Postsynaptic FMRP Promotes the Pruning of Cell-to-Cell Connections among Pyramidal Neurons in the L5A Neocortical Network

(2014) A. B. Patel et al.   JOURNAL OF NEUROSCIENCE

Fmr1 KO and Fenobam Treatment Differentially Impact Distinct Synapse Populations of Mouse Neocortex

(2014) Gordon X. Wang et al.   NEURON

Behavioral consequences of GABAergic neuronal diversity

(2013) Matthew Lovett-Barron et al.   CURRENT OPINION IN NEUROBIOLOGY

A Target Cell-Specific Role for Presynaptic Fmr1 in Regulating Glutamate Release onto Neocortical Fast-Spiking Inhibitory Neurons

(2013) A. B. Patel et al.   JOURNAL OF NEUROSCIENCE

Distal Dendritic Inputs Control Neuronal Activity by Heterosynaptic Potentiation of Proximal Inputs

(2013) E. B. Han et al.   JOURNAL OF NEUROSCIENCE

Circuit level defects in the developing neocortex of Fragile X mice

(2013) J Tiago Gonçalves et al.   NATURE NEUROSCIENCE

FMRP Regulates Neurotransmitter Release and Synaptic Information Transmission by Modulating Action Potential Duration via BK Channels

(2013) Pan-Yue Deng et al.   NEURON

A Cortico-Hippocampal Learning Rule Shapes Inhibitory Microcircuit Activity to Enhance Hippocampal Information Flow

(2013) Jayeeta Basu et al.   NEURON

Neurogliaform cells dynamically regulate somatosensory integration via synapse-specific modulation

(2012) Ramesh Chittajallu et al.   NATURE NEUROSCIENCE

Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABAB Receptors with Arbaclofen

(2012) C. Henderson et al.   Science Translational Medicine

Effects of STX209 (Arbaclofen) on Neurobehavioral Function in Children and Adults with Fragile X Syndrome: A Randomized, Controlled, Phase 2 Trial

(2012) E. M. Berry-Kravis et al.   Science Translational Medicine

GABAB receptor modulation of synaptic function

(2011) Jason R Chalifoux et al.   CURRENT OPINION IN NEUROBIOLOGY

Fragile X Syndrome: The GABAergic System and Circuit Dysfunction

(2011) Scott M. Paluszkiewicz et al.   DEVELOPMENTAL NEUROSCIENCE

Short-Term Plasticity Optimizes Synaptic Information Transmission

(2011) Z. Rotman et al.   JOURNAL OF NEUROSCIENCE

Abnormal Presynaptic Short-Term Plasticity and Information Processing in a Mouse Model of Fragile X Syndrome

(2011) P.-Y. Deng et al.   JOURNAL OF NEUROSCIENCE

Subchronic Administration and Combination Metabotropic Glutamate and GABAB Receptor Drug Therapy in Fragile X Syndrome

(2011) L. K. K. Pacey et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Defective GABAergic Neurotransmission and Pharmacological Rescue of Neuronal Hyperexcitability in the Amygdala in a Mouse Model of Fragile X Syndrome

(2010) J. L. Olmos-Serrano et al.   JOURNAL OF NEUROSCIENCE

Basal GABA Regulates GABABR Conformation and Release Probability at Single Hippocampal Synapses

(2010) Tal Laviv et al.   NEURON

The GABAB1a Isoform Mediates Heterosynaptic Depression at Hippocampal Mossy Fiber Synapses

(2009) N. Guetg et al.   JOURNAL OF NEUROSCIENCE

Feed-forward inhibition as a buffer of the neuronal input-output relation

(2009) M. Ferrante et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Downregulation of Tonic GABAergic Inhibition in a Mouse Model of Fragile X Syndrome

(2008) Giulia Curia et al.   CEREBRAL CORTEX

Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome

(2008) Jay R. Gibson et al.   JOURNAL OF NEUROPHYSIOLOGY

Direct Cortical Inputs Erase Long-Term Potentiation at Schaffer Collateral Synapses

(2008) Y. Izumi et al.   JOURNAL OF NEUROSCIENCE

GABAB Receptor Modulation of Feedforward Inhibition through Hippocampal Neurogliaform Cells

(2008) C. J. Price et al.   JOURNAL OF NEUROSCIENCE

Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function

(2008) Gary J. Bassell et al.   NEURON

Abnormal Striatal GABA Transmission in the Mouse Model for the Fragile X Syndrome

(2007) Diego Centonze et al.   BIOLOGICAL PSYCHIATRY