Pirh2 modulates amyloid‐β aggregation through the regulation of glucose‐regulated protein 78 and chaperone‐mediated signaling

Guanabenz mitigates the neuropathological alterations and cell death in Alzheimer’s disease

(2022) Abhishek Singh et al.   CELL AND TISSUE RESEARCH

ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments

(2022) Amir Ajoolabady et al.   Cell Death & Disease

UBA52 Is Crucial in HSP90 Ubiquitylation and Neurodegenerative Signaling during Early Phase of Parkinson’s Disease

(2022) Shubhangini Tiwari et al.   Cells

Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities

(2021) Marlene F. Schmidt et al.   CELL DEATH AND DIFFERENTIATION

Rivastigmine attenuates the Alzheimer's disease related protein degradation and apoptotic neuronal death signaling

(2021) Parul Gupta et al.   BIOCHEMICAL JOURNAL

The Roles of the Ubiquitin–Proteasome System in the Endoplasmic Reticulum Stress Pathway

(2021) Junyan Qu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Calcium transfer between endoplasmic reticulum and mitochondria in liver diseases

(2021) Chaonan Jin et al.   FEBS LETTERS

Mechanism for antiParkinsonian effect of resveratrol: Involvement of transporters, synaptic proteins, dendrite arborization, biochemical alterations, ER stress and apoptosis

(2021) Ashish Singh et al.   FOOD AND CHEMICAL TOXICOLOGY

The potential role of Keap1-Nrf2 pathway in the pathogenesis of Alzheimer’s disease, type 2 diabetes, and type 2 diabetes-related Alzheimer’s disease

(2021) Ling He et al.   METABOLIC BRAIN DISEASE

The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase

(2021) Alexandra Daks et al.   Cell Death & Disease

Roles and Mechanisms of the Protein Quality Control System in Alzheimer’s Disease

(2021) Yaping Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploration of Aberrant E3 Ligases Implicated in Alzheimer’s Disease and Development of Chemical Tools to Modulate Their Function

(2021) Frances M. Potjewyd et al.   Frontiers in Cellular Neuroscience

Regulation of aberrant proteasome activity re‐establishes plasticity and long‐term memory in an animal model of Alzheimer's disease

(2020) Kumar Krishna‐K et al.   FASEB JOURNAL

Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases

(2020) Rose Ghemrawi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reductive stress promotes protein aggregation and impairs neurogenesis

(2020) Kishore Kumar S Narasimhan et al.   Redox Biology

Ubiquitin, Autophagy and Neurodegenerative Diseases

(2020) Yoshihisa Watanabe et al.   Cells

Novel target for treating Alzheimer’s Diseases: Crosstalk between the Nrf2 pathway and autophagy

(2020) Weiwei Zhang et al.   AGEING RESEARCH REVIEWS

Disrupted ubiquitin proteasome system underlying tau accumulation in Alzheimer’s disease

(2020) Fang-lin Weng et al.   NEUROBIOLOGY OF AGING

The Hsp70 chaperone network

(2019) Rina Rosenzweig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death

(2018) Saverio Marchi et al.   CELL CALCIUM

Involvement of glucose related energy crisis and endoplasmic reticulum stress: Insinuation of streptozotocin induced Alzheimer's like pathology

(2018) Joyshree Biswas et al.   CELLULAR SIGNALLING

Endoplasmic Reticulum Stress signalling - from basic mechanisms to clinical applications

(2018) Aitor Almanza et al.   FEBS Journal

Nrf2-p62 autophagy pathway and its response to oxidative stress in hepatocellular carcinoma

(2018) Desirée Bartolini et al.   Translational Research

The endoplasmic reticulum (ER) chaperone BiP is a master regulator of ER functions: Getting by with a little help from ERdj friends

(2018) Kristine Faye R. Pobre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hsp70 - a master regulator in protein degradation

(2017) María Rosario Fernández-Fernández et al.   FEBS LETTERS

Ubiquitin signaling and autophagy

(2017) Paolo Grumati et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Streptozotocin alters glucose transport, connexin expression and endoplasmic reticulum functions in neurons and astrocytes

(2017) Joyshree Biswas et al.   NEUROSCIENCE

The role of ubiquitin proteasomal system and autophagy-lysosome pathway in Alzheimer’s disease

(2017) Yuan Zhang et al.   REVIEWS IN THE NEUROSCIENCES

The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

(2017) Rachel E. Lackie et al.   Frontiers in Neuroscience

Alzheimer's Disease and Molecular Chaperones: Current Knowledge and the Future of Chaperonotherapy

(2016) Antonella Marino Gammazza et al.   CURRENT PHARMACEUTICAL DESIGN

The ubiquitin proteasomal system: a potential target for the management of Alzheimer's disease

(2016) Kundlik Gadhave et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Oxidative stress response and Nrf2 signaling in aging

(2015) Hongqiao Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Streptozotocin Induced Neurotoxicity Involves Alzheimer’s Related Pathological Markers: a Study on N2A Cells

(2015) Joyshree Biswas et al.   MOLECULAR NEUROBIOLOGY

The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer’s Disease

(2015) Yanuar Alan Sulistio et al.   MOLECULAR NEUROBIOLOGY

Screening strategies to identify HSP70 modulators to treat Alzheimer’s disease

(2015) Jayanthi Repalli et al.   Drug Design Development and Therapy

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

Targeting Hsp90 and its co-chaperones to treat Alzheimer’s disease

(2014) Laura J Blair et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Regulation of protein turnover by heat shock proteins

(2014) Perinur Bozaykut et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress in Alzheimer’s disease

(2014) Zhichun Chen et al.   Neuroscience Bulletin

Heat Shock Protein 90 in Alzheimer’s Disease

(2014) Jiang-Rong Ou et al.   Biomed Research International

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Pirh2

(2013) Marie-jo Halaby et al.   CELL CYCLE

Chaperone machines for protein folding, unfolding and disaggregation

(2013) Helen Saibil   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Small heat shock proteins, protein degradation and protein aggregation diseases

(2010) Michel J. Vos et al.   Autophagy

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Heat shock proteins in neurodegenerative diseases: Pathogenic roles and therapeutic implications

(2009) Hiroaki Adachi et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA