Cell plasticity modulation by flavonoids in resistant breast carcinoma targeting the nuclear factor kappa B signaling

Potential Phytochemicals for Prevention of Familial Breast Cancer with BRCA Mutations

(2023) Aliasgar Fakruddin Shahiwala et al.   CURRENT DRUG TARGETS

Flavonoids attenuate cancer metabolism by modulating Lipid metabolism, amino acids, ketone bodies and redox state mediated by Nrf2

(2023) Marek Samec et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Resveratrol Modulates Chemosensitisation to 5-FU via β1-Integrin/HIF-1α Axis in CRC Tumor Microenvironment

(2023) Aranka Brockmueller et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells via lipid metabolism regulation at least partly by suppressing the Akt/mTOR/SREBP1 pathway

(2023) Lu‐Chang Liang et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

TIPE2 sensitizes breast cancer cells to paclitaxel by suppressing drug-induced autophagy and cancer stem cell properties

(2023) Wei Hu et al.   Human Cell

Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: A comprehensive review

(2023) Md Sohel et al.   Cancer Medicine

Therapy-resistant breast cancer in focus: Clinically relevant mitigation by flavonoids targeting cancer stem cells

(2023) Alena Mazurakova et al.   Frontiers in Pharmacology

Significance of flavonoids targeting PI3K/Akt/HIF-1α signaling pathway in therapy-resistant cancer cells – A potential contribution to the predictive, preventive, and personalized medicine

(2023) Alena Mazurakova et al.   Journal of Advanced Research

Functionalized Lipid Nanocarriers for Simultaneous Delivery of Docetaxel and Tariquidar to Chemoresistant Cancer Cells

(2023) Chang Hyun Kim et al.   Pharmaceuticals

Natural products as drug candidates for breast cancer (Review)

(2023) Nitin Telang   Oncology Letters

Targeting NF-κB Signaling in Cancer Stem Cells: A Narrative Review

(2022) Barbara Kaltschmidt et al.   Biomedicines

NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition

(2022) Sepideh Mirzaei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Clinical study on Yanghe decoction in improving neo-adjuvant chemotherapy efficacy and immune function of breast cancer patients

(2022) Xinyue Zhang et al.   MEDICINE

ROR activation by Nobiletin enhances antitumor efficacy via suppression of IκB/NF-κB signaling in triple-negative breast cancer

(2022) Eunju Kim et al.   Cell Death & Disease

JAK/STAT Signaling: Molecular Targets, Therapeutic Opportunities, and Limitations of Targeted Inhibitions in Solid Malignancies

(2022) Bilal Rah et al.   Frontiers in Pharmacology

Targeting Protein Kinase C for Cancer Therapy

(2022) Sijia He et al.   Cancers

Interleukin-1 and Nuclear Factor Kappa B Signaling Promote Breast Cancer Progression and Treatment Resistance

(2022) Sydney Diep et al.   Cells

Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care

(2022) Alena Mazurakova et al.   EPMA Journal

Genistin modulates high-mobility group box protein 1 (HMGB1) and nuclear factor kappa-B (NF-κB) in Ehrlich-ascites-carcinoma-bearing mice

(2022) Mohamed A. Saleh et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Flavonoids Targeting the mTOR Signaling Cascades in Cancer: A Potential Crosstalk in Anti-Breast Cancer Therapy

(2022) Yaseen Hussain et al.   Oxidative Medicine and Cellular Longevity

Dietary phytochemicals/nutrients as promising protector of breast cancer development: a comprehensive analysis

(2022) Suman Kumar Samanta et al.   Pharmacological Reports

Breast Cancer Stem Cells: Signaling Pathways, Cellular Interactions, and Therapeutic Implications

(2022) Lei Wang et al.   Cancers

PI3K/AKT/mTOR-Targeted Therapy for Breast Cancer

(2022) Kunrui Zhu et al.   Cells

EMT mechanism in breast cancer metastasis and drug resistance: Revisiting molecular interactions and biological functions

(2022) Mehrdad Hashemi et al.   BIOMEDICINE & PHARMACOTHERAPY

Kaempferol attenuates viability of ex-vivo cultured post-NACT breast tumor explants through downregulation of p53 induced stemness, inflammation and apoptosis evasion pathways

(2022) Sourav Kumar Nandi et al.   PATHOLOGY RESEARCH AND PRACTICE

NF-κB inhibitors gifted by nature: The anticancer promise of polyphenol compounds

(2022) Chengcheng Guan et al.   BIOMEDICINE & PHARMACOTHERAPY

Transition of amyloid/mutant p53 from tumor suppressor to an oncogene and therapeutic approaches to ameliorate metastasis and cancer stemness

(2022) Shinjinee Sengupta et al.   Cancer Cell International

Cancer plasticity: Investigating the causes for this agility

(2022) Shubhraneel Saha et al.   SEMINARS IN CANCER BIOLOGY

Flavonoids Targeting HIF-1: Implications on Cancer Metabolism

(2021) Marek Samec et al.   Cancers

Inflammation-Driven Breast Tumor Cell Plasticity: Stemness/EMT, Therapy Resistance and Dormancy

(2021) Tamir Baram et al.   Frontiers in Oncology

Nuclear factor-κB signaling inhibitors revert multidrug-resistance in breast cancer cells

(2021) Shifaa M. Abdin et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Novel molecular regulators of breast cancer stem cell plasticity and heterogeneity

(2021) Rui Zhang et al.   SEMINARS IN CANCER BIOLOGY

Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer

(2021) Chao Dong et al.   Frontiers in Pharmacology

Attribution of NF-κB Activity to CHUK/IKKα-Involved Carcinogenesis

(2021) Xin Li et al.   Cancers

Flavonoids as an effective sensitizer for anti-cancer therapy: insights into multi-faceted mechanisms and applicability towards individualized patient profiles

(2021) Alena Liskova et al.   EPMA Journal

Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?

(2021) Sepideh Mirzaei et al.   CANCER LETTERS

Protective Effects of Flavonoids Against Mitochondriopathies and Associated Pathologies: Focus on the Predictive Approach and Personalized Prevention

(2021) Lenka Koklesova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

EGFR in Cancer: Signaling Mechanisms, Drugs, and Acquired Resistance

(2021) Mary Luz Uribe et al.   Cancers

Enzymatic Metabolism of Flavonoids by Gut Microbiota and Its Impact on Gastrointestinal Cancer

(2021) Raghad Khalid AL-Ishaq et al.   Cancers

Phytochemicals targeting NF-κB signaling: Potential anti-cancer interventions

(2021) Akansha Chauhan et al.   Journal of Pharmaceutical Analysis

Ampelopsin Suppresses Stem Cell Properties Accompanied by Attenuation of Oxidative Phosphorylation in Chemo- and Radio-Resistant MDA-MB-231 Breast Cancer Cells

(2021) Vi Nguyen-Phuong Truong et al.   Pharmaceuticals

Overexpression of NF-kB as a predictor of neoadjuvant chemotherapy response in breast cancer

(2021) Elridho Sampepajung et al.   Breast Disease

p53 signaling in cancer progression and therapy

(2021) Hany E. Marei et al.   Cancer Cell International

Traditional Chinese medicine reverses cancer multidrug resistance and its mechanism

(2021) J. Wei et al.   Clinical & Translational Oncology

Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics

(2021) Ari Meerson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Paclitaxel resistance is mediated by NF‑κB on mesenchymal primary breast cancer cells

(2021) José Esparza‑lópez et al.   Oncology Letters

Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid Cancers

(2021) Martha Dillon et al.   Cancers

Flavonoids against non-physiologic inflammation attributed to cancer initiation, development, and progression—3PM pathways

(2021) Peter Kubatka et al.   EPMA Journal

Flavonoids Synergistically Enhance the Anti-Glioblastoma Effects of Chemotherapeutic Drugs

(2021) Kevin Zhai et al.   Biomolecules

P-Glycoprotein (ABCB1/MDR1) and BCRP (ABCG2) Limit Brain Accumulation and Cytochrome P450-3A (CYP3A) Restricts Oral Exposure of the RET Inhibitor Selpercatinib (RETEVMO)

(2021) Yaogeng Wang et al.   Pharmaceuticals

Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity

(2020) Shannon Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibitory Effect of Hesperidin on the Expression of Programmed Death Ligand (PD-L1) in Breast Cancer

(2020) Prachya Kongtawelert et al.   MOLECULES

ERK/MAPK signalling pathway and tumorigenesis (Review)

(2020) Yan‑Jun Guo et al.   Experimental and Therapeutic Medicine

Anti-Angiogenic Effects of Phytochemicals on miRNA Regulating Breast Cancer Progression

(2020) Elizabeth Varghese et al.   Biomolecules

Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses

(2020) Peter Kubatka et al.   MOLECULES

Life, death, and autophagy in cancer: NF-κB turns up everywhere

(2020) Daniela Verzella et al.   Cell Death & Disease

Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression

(2020) Dawei Yang et al.   ARCHIVES OF TOXICOLOGY

Association of the Epithelial–Mesenchymal Transition (EMT) with Cisplatin Resistance

(2020) Milad Ashrafizadeh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alpinetin inhibits breast cancer growth by ROS/NF‐κB/HIF‐1α axis

(2020) Tao Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy

(2020) Hui Hua et al.   Journal of Hematology & Oncology

Flavonoids in Cancer Metastasis

(2020) Alena Liskova et al.   Cancers

JAK-STAT Signalling Pathway in Cancer

(2020) Andrew J. Brooks et al.   Cancers

Flavonoids against the Warburg phenotype—concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism

(2020) Marek Samec et al.   EPMA Journal

Targeting NF-κB Signaling by Calebin A, a Compound of Turmeric, in Multicellular Tumor Microenvironment: Potential Role of Apoptosis Induction in CRC Cells

(2020) Constanze Buhrmann et al.   Biomedicines

Icariin‐induced inhibition of SIRT6/NF‐κB triggers redox mediated apoptosis and enhances anti‐tumor immunity in triple‐negative breast cancer

(2020) Linjiang Song et al.   CANCER SCIENCE

Implications of flavonoids as potential modulators of cancer neovascularity

(2020) Alena Liskova et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Administration with hyperoside sensitizes breast cancer cells to paclitaxel by blocking the TLR4 signaling

(2020) Ting Sun et al.   MOLECULAR AND CELLULAR PROBES

PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers

(2020) Rui Liu et al.   Cell Death & Disease

Hold on or Cut? Integrin- and MMP-Mediated Cell–Matrix Interactions in the Tumor Microenvironment

(2020) Stephan Niland et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma

(2020) Peter Kubatka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Tumor Microenvironment as a Driving Force of Breast Cancer Stem Cell Plasticity

(2020) Flavia Fico et al.   Cancers

Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3

(2019) Amer Ali Abd El-Hafeez et al.   Pharmacological Reports

Baicalein Suppresses Stem Cell-Like Characteristics in Radio- and Chemoresistant MDA-MB-231 Human Breast Cancer Cells through Up-Regulation of IFIT2

(2019) So Koh et al.   Nutrients

Viewing the Emphasis on State-of-the-Art Magnetic Nanoparticles: Synthesis, Physical Properties, and Applications in Cancer Theranostics

(2019) Satyavani Kaliamurthi et al.   CURRENT PHARMACEUTICAL DESIGN

Oroxylin A Suppresses the Cell Proliferation, Migration, and EMT via NF-κB Signaling Pathway in Human Breast Cancer Cells

(2019) XiaoHu Sun et al.   Biomed Research International

Reversal of Multidrug Resistance in Cancer by Multi-Functional Flavonoids

(2019) Qingmei Ye et al.   Frontiers in Oncology

The multi-factorial nature of clinical multidrug resistance in cancer

(2019) Yehuda G. Assaraf et al.   DRUG RESISTANCE UPDATES

FoxO3a as a Positive Prognostic Marker and a Therapeutic Target in Tamoxifen-Resistant Breast Cancer

(2019) Michele Pellegrino et al.   Cancers

Total Dietary Fats, Fatty Acids, and Omega-3/Omega-6 Ratio as Risk Factors of Breast Cancer in the Polish Population – a Case-Control Study

(2019) DOROTA DYDJOW-BENDEK et al.   IN VIVO

Hyperoside Induces Breast Cancer Cells Apoptosis via ROS-Mediated NF-κB Signaling Pathway

(2019) Jinxia Qiu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IΚΚε cooperates with either MEK or non-canonical NF-kB driving growth of triple-negative breast cancer cells in different contexts

(2018) Carrie D. House et al.   BMC CANCER

CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness

(2018) Shicheng Su et al.   CELL

Quercetin reversed MDR in breast cancer cells through down-regulating P-gp expression and eliminating cancer stem cells mediated by YB-1 nuclear translocation

(2018) Shizheng Li et al.   PHYTOTHERAPY RESEARCH

Role of the NFκB-signaling pathway in cancer

(2018) Longzheng Xia et al.   OncoTargets and Therapy

An NFκB-dependent mechanism of tumor cell plasticity and lateral transmission of aggressive features

(2018) Nancy Adriana Espinoza-Sánchez et al.   Oncotarget

Green Tea Catechins: Their Use in Treating and Preventing Infectious Diseases

(2018) Wanda C. Reygaert   Biomed Research International

Curcumin and paclitaxel induce cell death in breast cancer cell lines

(2018) Gloria Calaf et al.   ONCOLOGY REPORTS

Orientin inhibits invasion by suppressing MMP-9 and IL-8 expression via the PKCα/ ERK/AP-1/STAT3-mediated signaling pathways in TPA-treated MCF-7 breast cancer cells

(2018) Soo-Jin Kim et al.   PHYTOMEDICINE

Synthesis and antiproliferative activities of doxorubicin thiol conjugates and doxorubicin-SS-cyclic peptide

(2018) Shaban Darwish et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K/AKT pathway in vivo and vitro

(2018) Wanjun Yan et al.   Drug Design Development and Therapy

Sensitization of Drug Resistant Cancer Cells: A Matter of Combination Therapy

(2018) Meghan Leary et al.   Cancers

Flavonoids in Cancer and Apoptosis

(2018) Mariam Abotaleb et al.   Cancers

Exploring the pharmacological mechanism of Yanghe Decoction on HER2-positive breast cancer by a network pharmacology approach

(2017) Liuting Zeng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

NF-κB as the main node of resistance to receptor tyrosine kinase inhibitors in triple-negative breast cancer

(2017) Behrad Darvishi et al.   TUMOR BIOLOGY

Aberrant control of NF-κB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode

(2017) A. Vlahopoulos Spiros   Cancer Biology & Medicine

Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells

(2017) Kevin M. Perrott et al.   GeroScience

NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells

(2017) Bruno R. B. Pires et al.   PLoS One

Growth inhibitory effect of paratocarpin E, a prenylated chalcone isolated from Euphorbia humifusa Wild., by induction of autophagy and apoptosis in human breast cancer cells

(2016) Suyu Gao et al.   BIOORGANIC CHEMISTRY

Tumor microenvironment-mediated chemoresistance in breast cancer

(2016) Kobra velaei et al.   BREAST

Young Barley Indicates Antitumor Effects in Experimental Breast Cancer In Vivo and In Vitro

(2016) Peter Kubatka et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Targeting transcription factor STAT3 for cancer prevention and therapy

(2016) Edna Zhi Pei Chai et al.   PHARMACOLOGY & THERAPEUTICS

Sinapine reverses multi-drug resistance in MCF-7/dox cancer cells by downregulating FGFR4/FRS2α-ERK1/2 pathway-mediated NF-κB activation

(2016) Ying Guo et al.   PHYTOMEDICINE

Overview of Oroxylin A: A Promising Flavonoid Compound

(2016) Lu Lu et al.   PHYTOTHERAPY RESEARCH

NFκBP65 transcription factor modulates resistance to doxorubicin through ABC transporters in breast cancer

(2016) Kobra Velaei et al.   Breast Cancer

Effect of Tea Polyphenol Compounds on Anticancer Drugs in Terms of Anti-Tumor Activity, Toxicology, and Pharmacokinetics

(2016) Jianhua Cao et al.   Nutrients

NF-kappaΒ-inducing kinase regulates stem cell phenotype in breast cancer

(2016) Karla Vazquez-Santillan et al.   Scientific Reports

Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches

(2016) Mi Park et al.   Cells

The NF-κB Pathway and Cancer Stem Cells

(2016) Amanda Rinkenbaugh et al.   Cells

Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction pathways

(2016) Tayyaba Afsar et al.   Scientific Reports

In Vivo Anti-Tumor Effects of Flavokawain A in 4T1 Breast Cancer Cell-Challenged Mice

(2015) Nadiah Abu et al.   Anti-Cancer Agents in Medicinal Chemistry

Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer

(2015) Mohamed Salah I Abaza et al.   Cancer Cell International

Fruit peel polyphenols demonstrate substantial anti-tumour effects in the model of breast cancer

(2015) Peter Kubatka et al.   EUROPEAN JOURNAL OF NUTRITION

Fisetin regulates TPA-induced breast cell invasion by suppressing matrix metalloproteinase-9 activation via the PKC/ROS/MAPK pathways

(2015) Eun-Mi Noh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ganoderma lucidum derived ganoderenic acid B reverses ABCB1-mediated multidrug resistance in HepG2/ADM cells

(2015) DAO-LU LIU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells

(2015) Jin Mo Ku et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Sequential release of epigallocatechin gallate and paclitaxel from PLGA-casein core/shell nanoparticles sensitizes drug-resistant breast cancer cells

(2015) Sreeja Narayanan et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo

(2015) Deyong Jia et al.   Oncotarget

Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer

(2015) Alba Dalmases et al.   Oncotarget

Curcumin and its Analogues (PGV-0 and PGV-1) Enhance Sensitivity of Resistant MCF-7 Cells to Doxorubicin through Inhibition of HER2 and NF-kB Activation

(2014) Edy Meiyanto et al.   Asian Pacific Journal of Cancer Prevention

Expression of glutathione, glutathione peroxidase and glutathione S-transferase pi in canine mammary tumors

(2014) Camila Leonel et al.   BMC Veterinary Research

Targeting the NFκB Signaling Pathways for Breast Cancer Prevention and Therapy

(2014) Wei Wang et al.   CURRENT MEDICINAL CHEMISTRY

Delphinidin Suppresses PMA-Induced MMP-9 Expression by Blocking the NF-κB Activation Through MAPK Signaling Pathways in MCF-7 Human Breast Carcinoma Cells

(2014) Nam-Kyung Im et al.   JOURNAL OF MEDICINAL FOOD

LFG-500 Inhibits the Invasion of Cancer Cells via Down-Regulation of PI3K/AKT/NF-κB Signaling Pathway

(2014) Chenglin Li et al.   PLoS One

NF-κB Affects Proliferation and Invasiveness of Breast Cancer Cells by Regulating CD44 Expression

(2014) Shannon M. Smith et al.   PLoS One

Peptides genetically selected for NF- B activation cooperate with oncogene Ras and model carcinogenic role of inflammation

(2014) V. Natarajan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Luteolin 8-C-β-fucopyranoside inhibits invasion and suppresses TPA-induced MMP-9 and IL-8 via ERK/AP-1 and ERK/NF-κB signaling in MCF-7 breast cancer cells

(2013) Su-Ho Park et al.   BIOCHIMIE

Flavonoids, derived from traditional chinese medicines, show roles in the differentiation of neurons: Possible targets in developing health food products

(2013) Sherry L. Xu et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Epithelial Growth Factor Receptor–Activated Nuclear Factor κB Signaling and Its Role in Epithelial Growth Factor Receptor–Associated Tumors

(2013) Deng Pan et al.   CANCER JOURNAL

Survivin up-regulates the expression of breast cancer resistance protein (BCRP) through attenuating the suppression of p53 on NF-κB expression in MCF-7/5-FU cells

(2013) Qing-ping Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-κB-mediated antiapoptotic pathway

(2013) C-K Huang et al.   ONCOGENE

Imatinib Reverses Doxorubicin Resistance by Affecting Activation of STAT3-Dependent NF-κB and HSP27/p38/AKT Pathways and by Inhibiting ABCB1

(2013) Jonathan T. Sims et al.   PLoS One

SNAI1-Mediated Epithelial-Mesenchymal Transition Confers Chemoresistance and Cellular Plasticity by Regulating Genes Involved in Cell Death and Stem Cell Maintenance

(2013) Soyoung Lim et al.   PLoS One

Targeting Nuclear Factor-Kappa B to Overcome Resistance to Chemotherapy

(2013) P. Godwin et al.   Frontiers in Oncology

Neuropilin-1 is expressed by breast cancer stem-like cells and is linked to NF-κB activation and tumor sphere formation

(2012) Yelena Glinka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-Cancer Activities of Tea Epigallocatechin-3-Gallate in Breast Cancer Patients under Radiotherapy

(2012) G. Zhang et al.   CURRENT MOLECULAR MEDICINE

NF-κB regulation: lessons from structures

(2012) Gourisankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

Up-regulation of breast cancer resistance protein plays a role in HER2-mediated chemoresistance through PI3K/Akt and nuclear factor-kappa B signaling pathways in MCF7 breast cancer cells

(2011) W. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Autophagy and cancer therapy

(2011) Paola Maycotte et al.   CANCER BIOLOGY & THERAPY

Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients

(2011) E. Arvaniti et al.   HAEMATOLOGICA

Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: Involvement of cell line-specific apoptotic mechanisms

(2011) Prema S. Rao et al.   INTERNATIONAL JOURNAL OF CANCER

Curcumin Enhances the Efficacy of Chemotherapy by Tailoring p65NFκB-p300 Cross-talk in Favor of p53-p300 in Breast Cancer

(2011) Gouri Sankar Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NFκB/p53 crosstalk—a promising new therapeutic target

(2010) Günter Schneider et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

(2010) Subash C. Gupta et al.   CANCER AND METASTASIS REVIEWS

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

A single NFκB system for both canonical and non-canonical signaling

(2010) Vincent Feng-Sheng Shih et al.   CELL RESEARCH

Molecular mechanism of suppression of MDR1 by puerarin from Pueraria lobata via NF-κB pathway and cAMP-responsive element transcriptional activity-dependent up-regulation of AMP-activated protein kinase in breast cancer MCF-7/adr cells

(2010) Tran Thi Hien et al.   MOLECULAR NUTRITION & FOOD RESEARCH

In vitro mechanism of action for the cytotoxicity elicited by the combination of epigallocatechin gallate and raloxifene in MDA-MB-231 cells

(2010) Rosengren   ONCOLOGY REPORTS

Targeting Inflammatory Pathways by Flavonoids for Prevention and Treatment of Cancer

(2010) Sahdeo Prasad et al.   PLANTA MEDICA

Targeting Inflammatory Pathways by Triterpenoids for Prevention and Treatment of Cancer

(2010) Vivek R. Yadav et al.   Toxins

The Role of Bcl-x(L) Protein in Nucleotide Excision Repair–Facilitated Cell Protection Against Cisplatin-Induced Apoptosis

(2009) Stephanie L. Lomonaco et al.   DNA AND CELL BIOLOGY

Her2 activates NF-κB and induces invasion through the canonical pathway involving IKKα

(2009) E C Merkhofer et al.   ONCOGENE

Induction of a pro-apoptotic ATM–NF-κB pathway and its repression by ATR in response to replication stress

(2008) Zhao-Hui Wu et al.   EMBO JOURNAL

Xanthohumol inhibits inflammatory factor production and angiogenesis in breast cancer xenografts

(2008) Rosário Monteiro et al.   JOURNAL OF CELLULAR BIOCHEMISTRY