Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts

(2015) Hyun Lim et al.   BIOCHEMICAL PHARMACOLOGY

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

(2015) Remi-Martin Laberge et al.   NATURE CELL BIOLOGY

Senescence-associated inflammatory responses: aging and cancer perspectives

(2015) Audrey Lasry et al.   TRENDS IN IMMUNOLOGY

Geroscience: Linking Aging to Chronic Disease

(2014) Brian K. Kennedy et al.   CELL

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Apigenin Protects Endothelial Cells from Lipopolysaccharide (LPS)-Induced Inflammation by Decreasing Caspase-3 Activation and Modulating Mitochondrial Function

(2013) Silvia Duarte et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glucocorticoids suppress selected components of the senescence-associated secretory phenotype

(2012) Remi-Martin Laberge et al.   AGING CELL

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Apigenin decreases cell viability and telomerase activity in human leukemia cell lines

(2012) R.G.P.T. Jayasooriya et al.   FOOD AND CHEMICAL TOXICOLOGY

NF-κB, Inflammation, and Metabolic Disease

(2011) Rebecca G. Baker et al.   Cell Metabolism

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

(2011) Adam Freund et al.   EMBO JOURNAL

Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin

(2011) Megumi Funakoshi-Tago et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Apigenin inhibits release of inflammatory mediators by blocking the NF-κB activation pathways in the HMC-1 cells

(2010) Ok-Hwa Kang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Apigenin inhibits allergen-induced airway inflammation and switches immune response in a murine model of asthma

(2010) Ruo-Ran Li et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Apigenin: A Promising Molecule for Cancer Prevention

(2010) Sanjeev Shukla et al.   PHARMACEUTICAL RESEARCH

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

(2010) Jean-Philippe Coppé et al.   PLoS One

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Ser276 Phosphorylation of NF-kB p65 by MSK1 Controls SCF Expression in Inflammation

(2009) Laurent Reber et al.   PLoS One

Cell surface-bound IL-1  is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

(2009) A. V. Orjalo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY