NF-κB regulation: lessons from structures

MicroRNAs, new effectors and regulators of NF-κB

(2012) Mark P. Boldin et al.   IMMUNOLOGICAL REVIEWS

Crystal structure of inhibitor of κB kinase β

(2011) Guozhou Xu et al.   NATURE

Detection of a ternary complex of NF- B and I B  with DNA provides insights into how I B  removes NF- B from transcription sites

(2011) S.-C. Sue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Specificity of Innate Immune Responses Is Enforced by Repression of Interferon Response Elements by NF- B p50

(2011) C. S. Cheng et al.   Science Signaling

IκBβ is an essential co-activator for LPS-induced IL-1β transcription in vivo

(2010) Melanie Scheibel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IκBβ acts to inhibit and activate gene expression during the inflammatory response

(2010) Ping Rao et al.   NATURE

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

(2009) Simin Rahighi et al.   CELL

NF- B1 p105 Regulates T Cell Homeostasis and Prevents Chronic Inflammation

(2009) M. Chang et al.   JOURNAL OF IMMUNOLOGY

Structural Basis for Recognition of Diubiquitins by NEMO

(2009) Yu-Chih Lo et al.   MOLECULAR CELL

The Nfkb1 and Nfkb2 Proteins p105 and p100 Function as the Core of High-Molecular-Weight Heterogeneous Complexes

(2009) Olga V. Savinova et al.   MOLECULAR CELL

Direct activation of protein kinases by unanchored polyubiquitin chains

(2009) Zong-Ping Xia et al.   NATURE

Ser276 Phosphorylation of NF-kB p65 by MSK1 Controls SCF Expression in Inflammation

(2009) Laurent Reber et al.   PLoS One

Kinetic control of negative feedback regulators of NF- B/RelA determines their pathogen- and cytokine-receptor signaling specificity

(2009) V. F.-S. Shih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of NF-κB activity through lysine monomethylation of p65

(2009) Chee-Kwee Ea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic enhancement of NF- B{middle dot}DNA dissociation by I B 

(2009) S. Bergqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

NF-κB dictates the degradation pathway of IκBα

(2008) Erika Mathes et al.   EMBO JOURNAL

NF-κB p52:RelB heterodimer recognizes two classes of κB sites with two distinct modes

(2008) Amanda J Fusco et al.   EMBO REPORTS

Repression of gene expression by unphosphorylated NF- B p65 through epigenetic mechanisms

(2008) J. Dong et al.   GENES & DEVELOPMENT

Bcl-3, a multifaceted modulator of NF-κB-mediated gene transcription

(2008) Scott Palmer et al.   IMMUNOLOGIC RESEARCH

Integrating Computational and Biochemical Studies to Explore Mechanisms in NF-κB Signaling

(2008) Jeffrey D. Kearns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Zinc Finger of NEMO Is a Functional Ubiquitin-binding Domain

(2008) Florence Cordier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution Structure of NEMO Zinc Finger and Impact of an Anhidrotic Ectodermal Dysplasia with Immunodeficiency-related Point Mutation

(2008) Florence Cordier et al.   JOURNAL OF MOLECULAR BIOLOGY

Pre-folding IκBα Alters Control of NF-κB Signaling

(2008) Stephanie M.E. Truhlar et al.   JOURNAL OF MOLECULAR BIOLOGY

Generation and Activation of Multiple Dimeric Transcription Factors within the NF- B Signaling System

(2008) S. Basak et al.   MOLECULAR AND CELLULAR BIOLOGY

A primer on ankyrin repeat function in TRP channels and beyond

(2008) Rachelle Gaudet   Molecular BioSystems

Crystal Structure of a vFlip-IKKγ Complex: Insights into Viral Activation of the IKK Signalosome

(2008) Claire Bagnéris et al.   MOLECULAR CELL

Proteolysis of NF-κB1 p105 is essential for T cell antigen receptor–induced proliferation

(2008) Srividya Sriskantharajah et al.   NATURE IMMUNOLOGY

Molecular dynamics of a κB DNA element: base flipping via cross-strand intercalative stacking in a microsecond-scale simulation

(2008) Cameron Mura et al.   NUCLEIC ACIDS RESEARCH

Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site

(2008) Mia Rushe et al.   STRUCTURE