The potential of the gut microbiome for identifying Alzheimer’s disease diagnostic biomarkers and future therapies

The gut microbiome modulates the transformation of microglial subtypes

(2023) Yu Huang et al.   MOLECULAR PSYCHIATRY

Gut microbiota in patients with Alzheimer’s disease spectrum: a systematic review and meta-analysis

(2022) Chun-Che Hung et al.   Aging-US

A Comprehensive Review on the Role of the Gut Microbiome in Human Neurological Disorders

(2022) Shokufeh Ghasemian Sorboni et al.   CLINICAL MICROBIOLOGY REVIEWS

Structural and functional neuroimaging of the effects of the gut microbiome

(2022) Rodrigo A. Montoro et al.   EUROPEAN RADIOLOGY

The Potential Role of Gut Microbiota in Alzheimer’s Disease: From Diagnosis to Treatment

(2022) Angelica Varesi et al.   Nutrients

Combination of gut microbiota and plasma amyloid-β as a potential index for identifying preclinical Alzheimer’s disease: a cross-sectional analysis from the SILCODE study

(2022) Can Sheng et al.   Alzheimers Research & Therapy

Gut Microbiota Composition Is Related to AD Pathology

(2022) Barbara J. H. Verhaar et al.   Frontiers in Immunology

The Impact of Systemic Inflammation on Alzheimer’s Disease Pathology

(2022) Junhua Xie et al.   Frontiers in Immunology

Microbiota‐microglia connections in age‐related cognition decline

(2022) Rui Zhou et al.   AGING CELL

Gut bacterial isoamylamine promotes age-related cognitive dysfunction by promoting microglial cell death

(2022) Yun Teng et al.   Cell Host & Microbe

The Oral and Fecal Microbiota in a Canadian Cohort of Alzheimer’s Disease

(2022) Mihai S. Cirstea et al.   JOURNAL OF ALZHEIMERS DISEASE

Targeted Metabolomic Analysis in Alzheimer’s Disease Plasma and Brain Tissue in Non-Hispanic Whites

(2022) Karel Kalecký et al.   JOURNAL OF ALZHEIMERS DISEASE

Peripheral Immune Cells and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease Pathology in Cognitively Intact Older Adults: The CABLE Study

(2022) Peng-Fei Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Bacterial Amyloid Curli Associated Gut Epithelial Neuroendocrine Activation Predominantly Observed in Alzheimer’s Disease Mice with Central Amyloid-β Pathology

(2022) Tushar K. Das et al.   JOURNAL OF ALZHEIMERS DISEASE

Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer’s disease

(2022) Diane Bairamian et al.   Molecular Neurodegeneration

Periodontal microorganisms and Alzheimer disease – A causative relationship?

(2022) Gert Jungbauer et al.   PERIODONTOLOGY 2000

Gastrodin From Gastrodia elata Enhances Cognitive Function and Neuroprotection of AD Mice via the Regulation of Gut Microbiota Composition and Inhibition of Neuron Inflammation

(2022) Opeyemi B. Fasina et al.   Frontiers in Pharmacology

Blood-Based Biomarkers for Alzheimer’s Disease Diagnosis and Progression: An Overview

(2022) Angelica Varesi et al.   Cells

Multifunctional Selenium Nanoparticles with Different Surface Modifications Ameliorate Neuroinflammation through the Gut Microbiota-NLRP3 Inflammasome-Brain Axis in APP/PS1 Mice

(2022) Licong Yang et al.   ACS Applied Materials & Interfaces

Effects of chronic vagal nerve stimulation in the treatment of β-AMYLOID induced neuropsychiatric symptoms

(2022) Metin Yesiltepe et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of Probiotic Fungi against Cognitive Impairment in Mice via Regulation of the Fungal Microbiota–Gut–Brain Axis

(2022) Tao Ye et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Scutellarin Modulates the Microbiota-Gut-Brain Axis and Improves Cognitive Impairment in APP/PS1 Mice

(2022) Shujuan Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroinflammation: A Distal Consequence of Periodontitis

(2022) X. Li et al.   JOURNAL OF DENTAL RESEARCH

Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia

(2022) Emily Connell et al.   Molecular Neurodegeneration

Delta/Notch signaling in glia maintains motor nerve barrier function and synaptic transmission by controlling matrix metalloproteinase expression

(2022) Mario R. Calderon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebrospinal Fluid Cortisol and Dehydroepiandrosterone Sulfate, Alzheimer’s Disease Pathology, and Cognitive Decline

(2022) Sami Ouanes et al.   Frontiers in Aging Neuroscience

Gut microbiota may be involved in Alzheimer’s disease pathology by dysregulating pyrimidine metabolism in APP/PS1 mice

(2022) Min Feng et al.   Frontiers in Aging Neuroscience

MetaProClust-MS1: an MS1 Profiling Approach for Large-Scale Microbiome Screening

(2022) Caitlin M. A. Simopoulos et al.   mSystems

Gut dysbiosis impairs hippocampal plasticity and behaviors by remodeling serum metabolome

(2022) Guoqiang Liu et al.   Gut Microbes

Targeting gut microbiota to alleviate neuroinflammation in Alzheimer’s disease

(2022) Vu Thu Thuy Nguyen et al.   ADVANCED DRUG DELIVERY REVIEWS

Effects of Donepezil Treatment on Brain Metabolites, Gut Microbiota, and Gut Metabolites in an Amyloid Beta-Induced Cognitive Impairment Mouse Pilot Model

(2022) Jae-Kwon Jo et al.   MOLECULES

Microglia states and nomenclature: A field at its crossroads

(2022) Rosa C. Paolicelli et al.   NEURON

Gut Microbiome and Mycobiome Alterations in an In Vivo Model of Alzheimer’s Disease

(2022) Valeria D’Argenio et al.   Genes

Gut microbiome alterations in preclinical Alzheimer’s disease

(2022) Joon Hyung Jung et al.   PLoS One

Persisting neuropsychiatric symptoms, Alzheimer’s disease, and cerebrospinal fluid cortisol and dehydroepiandrosterone sulfate

(2022) Sami Ouanes et al.   Alzheimers Research & Therapy

The Association of Blood-Based Inflammatory Factors IL-1β, TGF-β and CRP with Cognitive Function in Alzheimer’s Disease and Mild Cognitive Impairment

(2021) Jun Kyung Park et al.   Psychiatry Investigation

Altered Gut Microbial Metabolites in Amnestic Mild Cognitive Impairment and Alzheimer’s Disease: Signals in Host–Microbe Interplay

(2021) Li Wu et al.   Nutrients

Age-related cognitive decline is associated with microbiota-gut-brain axis disorders and neuroinflammation in mice

(2021) Mei-Ling Wu et al.   BEHAVIOURAL BRAIN RESEARCH

Gut Microbiome Features of Chinese Patients Newly Diagnosed with Alzheimer’s Disease or Mild Cognitive Impairment

(2021) Mingyan Guo et al.   JOURNAL OF ALZHEIMERS DISEASE

Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer’s disease

(2021) Robin M. Voigt et al.   PLoS One

The Role of Gut Bacterial Metabolites in Brain Development, Aging and Disease

(2021) Shirley Mei-Sin Tran et al.   Nutrients

Huanglian Jiedu decoction remodels the periphery microenvironment to inhibit Alzheimer’s disease progression based on the “brain-gut” axis through multiple integrated omics

(2021) Xinru Gu et al.   Alzheimers Research & Therapy

Structural and Functional Dysbiosis of Fecal Microbiota in Chinese Patients With Alzheimer's Disease

(2021) Zongxin Ling et al.   Frontiers in Cell and Developmental Biology

Diet quality, gut microbiota, and microRNAs associated with mild cognitive impairment in middle-aged and elderly Chinese population

(2021) Xiaona Zhang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Biomarkers for assessment of intestinal permeability in clinical practice

(2021) Benjamin Seethaler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mannan oligosaccharide attenuates cognitive and behavioral disorders in the 5xFAD Alzheimer's disease mouse model via regulating the gut microbiota-brain axis

(2021) Qing Liu et al.   BRAIN BEHAVIOR AND IMMUNITY

Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice

(2021) Yu Jiang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Improvement of Total Flavonoids from Dracocephalum moldavica L. in Rats with Chronic Mountain Sickness through 1H-NMR Metabonomics

(2021) Atiguli Maimaiti et al.   Evidence-based Complementary and Alternative Medicine

Gut Microbiota and Bipolar Disorder: An Overview on a Novel Biomarker for Diagnosis and Treatment

(2021) Lorenza Lucidi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut Microbiota Composition and Epigenetic Molecular Changes Connected to the Pathogenesis of Alzheimer’s Disease

(2021) Priyanka Nagu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Alzheimer’s disease and gut microbiota: does trimethylamine N-oxide (TMAO) play a role?

(2021) Pablo Arrona Cardoza et al.   NUTRITION REVIEWS

A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia

(2021) Shifu Xiao et al.   Alzheimers Research & Therapy

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

(2021) Alessio Vittorio Colombo et al.   eLife

Spatial Memory and Gut Microbiota Alterations Are Already Present in Early Adulthood in a Pre-clinical Transgenic Model of Alzheimer’s Disease

(2021) Paola C. Bello-Medina et al.   Frontiers in Neuroscience

Nano-Honokiol ameliorates the cognitive deficits in TgCRND8 mice of Alzheimer’s disease via inhibiting neuropathology and modulating gut microbiota

(2021) Chang Qu et al.   Journal of Advanced Research

Gut inflammation triggers C/EBPβ/δ‐secretase‐dependent gut‐to‐brain propagation of Aβ and Tau fibrils in Alzheimer’s disease

(2021) Chun Chen et al.   EMBO JOURNAL

Serum Corticosterone and Insulin Resistance as Early Biomarkers in the hAPP23 Overexpressing Mouse Model of Alzheimer’s Disease

(2021) Jhana O. Hendrickx et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Altered Gut Microbiota in Adults with Subjective Cognitive Decline: The SILCODE Study

(2021) Can Sheng et al.   JOURNAL OF ALZHEIMERS DISEASE

Microbiota regulate social behaviour via stress response neurons in the brain

(2021) Wei-Li Wu et al.   NATURE

Multiple roles of short-chain fatty acids in Alzheimer's disease

(2021) Hui Chen et al.   NUTRITION

Gut dysbiosis, defective autophagy and altered immune responses in neurodegenerative diseases: Tales of a vicious cycle

(2021) Saravana Babu Chidambaram et al.   PHARMACOLOGY & THERAPEUTICS

The Relationship Between the Gut Microbiome and Neurodegenerative Diseases

(2021) Xueling Zhu et al.   Neuroscience Bulletin

Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells

(2021) Louise Dupraz et al.   Cell Reports

Oral Administration of Resveratrol-Selenium-Peptide Nanocomposites Alleviates Alzheimer’s Disease-like Pathogenesis by Inhibiting Aβ Aggregation and Regulating Gut Microbiota

(2021) Changjiang Li et al.   ACS Applied Materials & Interfaces

Biomarkers used in Alzheimer’s disease diagnosis, treatment, and prevention

(2021) Yacoubou Abdoul Razak Mahaman et al.   AGEING RESEARCH REVIEWS

Microbes, metabolites and (synaptic) malleability, oh my! T he effect of the microbiome on synaptic plasticity

(2021) Ayala Glinert et al.   BIOLOGICAL REVIEWS

Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer’s Disease in a Multiethnic Population

(2021) Mia Nishikawa et al.   Current Alzheimer Research

GuanXinNing Tablet Attenuates Alzheimer’s Disease via Improving Gut Microbiota, Host Metabolites, and Neuronal Apoptosis in Rabbits

(2021) Feng Zhang et al.   Evidence-based Complementary and Alternative Medicine

Qisheng Wan formula ameliorates cognitive impairment of Alzheimer's disease rat via inflammation inhibition and intestinal microbiota regulation

(2021) Wei Xiong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Gut–microbiota–microglia–brain interactions in Alzheimer’s disease: knowledge-based, multi-dimensional characterization

(2021) QuanQiu Wang et al.   Alzheimers Research & Therapy

Inhibition of Rho Kinase by Fasudil Ameliorates Cognition Impairment in APP/PS1 Transgenic Mice via Modulation of Gut Microbiota and Metabolites

(2021) Yuqing Yan et al.   Frontiers in Aging Neuroscience

Sodium Oligomannate: First Approval

(2020) Yahiya Y. Syed   DRUGS

Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries

(2020) Tarini Shankar Ghosh et al.   GUT

Mixed evidence for the relationship between periodontitis and Alzheimer’s disease: A bidirectional Mendelian randomization study

(2020) Yi-Qian Sun et al.   PLoS One

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

(2020) Ygor Parladore Silva et al.   Frontiers in Endocrinology

Gut Microbiome Alterations Precede Cerebral Amyloidosis and Microglial Pathology in a Mouse Model of Alzheimer’s Disease

(2020) Yijing Chen et al.   Biomed Research International

Alzheimer’s disease beyond amyloid: Can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery?

(2020) Kevin Mullane et al.   BIOCHEMICAL PHARMACOLOGY

Intra‐gastrointestinal amyloid‐β1–42 oligomers perturb enteric function and induce Alzheimer's disease pathology

(2020) Yayi Sun et al.   JOURNAL OF PHYSIOLOGY-LONDON

Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells

(2020) Tyler J. Wenzel et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

New mechanism of neuroinflammation in Alzheimer's disease: The activation of NLRP3 inflammasome mediated by gut microbiota

(2020) Heping Shen et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Dysbiosis, gut barrier dysfunction and inflammation in dementia: a pilot study

(2020) Vanessa Stadlbauer et al.   BMC Geriatrics

Human-derived Bifidobacterium dentium modulates the mammalian serotonergic system and gut-brain axis

(2020) Melinda A. Engevik et al.   Cellular and Molecular Gastroenterology and Hepatology

Gut metagenomics-derived genes as potential biomarkers of Parkinson’s disease

(2020) Yiwei Qian et al.   BRAIN

Gut microbiome mediated epigenetic regulation of brain disorder and application of machine learning for multi-omics data analysis

(2020) Harpreet Kaur et al.   GENOME

Gut Microbiota and Intestinal Trans-Epithelial Permeability

(2020) Bénédicte Allam-Ndoul et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer’s Disease

(2020) Moira Marizzoni et al.   JOURNAL OF ALZHEIMERS DISEASE

Gut Microbiota and Dysbiosis in Alzheimer’s Disease: Implications for Pathogenesis and Treatment

(2020) Shan Liu et al.   MOLECULAR NEUROBIOLOGY

Relationship between Wine Consumption, Diet and Microbiome Modulation in Alzheimer’s Disease

(2020) M. Victoria Moreno-Arribas et al.   Nutrients

A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia

(2020) Tao Wang et al.   Alzheimers Research & Therapy

Gut mycobiome and its interaction with diet, gut bacteria and alzheimer's disease markers in subjects with mild cognitive impairment: A pilot study

(2020) Ravinder Nagpal et al.   EBioMedicine

The Intestinal Barrier and Current Techniques for the Assessment of Gut Permeability

(2020) Ida Schoultz et al.   Cells

Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?

(2020) Fangda Leng et al.   Nature Reviews Neurology

The Microbiota–Gut–Brain Axis and Alzheimer’s Disease: Neuroinflammation Is to Blame?

(2020) Ashwinipriyadarshini Megur et al.   Nutrients

Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease

(2020) Md. Habibur Rahman et al.   Frontiers in Pharmacology

Inflammatory markers in Alzheimer’s disease and mild cognitive impairment: a meta-analysis and systematic review of 170 studies

(2019) Xue-Ning Shen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cholecystokinin and Alzheimer’s Disease: A Biomarker of Metabolic Function, Neural Integrity, and Cognitive Performance

(2019) Alexandra Plagman et al.   NEUROBIOLOGY OF AGING

Brain-Gut-Microbiota Axis in Alzheimer’s Disease

(2019) Karol Kowalski et al.   Journal of Neurogastroenterology and Motility

Peripheral inflammatory biomarkers in Alzheimer's disease and mild cognitive impairment: a systematic review and meta-analysis

(2019) Cen Su et al.   Psychogeriatrics

Gut Microbe to Brain Signaling: What Happens in Vagus…

(2019) Christine Fülling et al.   NEURON

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

Gut microbiota in neurodegenerative disorders

(2019) Suparna Roy Sarkar et al.   JOURNAL OF NEUROIMMUNOLOGY

Systemic and CNS inflammation crosstalk: implications for Alzheimer’s Disease

(2019) Evi Paouri et al.   Current Alzheimer Research

Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort

(2019) Ping Liu et al.   BRAIN BEHAVIOR AND IMMUNITY

Sex-specific effects of microbiome perturbations on cerebral Aβ amyloidosis and microglia phenotypes

(2019) Hemraj B. Dodiya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gut Microbiota Disorder, Gut Epithelial and Blood–Brain Barrier Dysfunctions in Etiopathogenesis of Dementia: Molecular Mechanisms and Signaling Pathways

(2019) Menizibeya O. Welcome   NEUROMOLECULAR MEDICINE

High-fat diet causes psychiatric disorders in mice by increasing Proteobacteria population

(2019) Mi-Young Jeong et al.   NEUROSCIENCE LETTERS

Epigenetic Modifications in Alzheimer’s Neuropathology and Therapeutics

(2019) Michelle Esposito et al.   Frontiers in Neuroscience

CA-30, an oligosaccharide fraction derived from Liuwei Dihuang decoction, ameliorates cognitive deterioration via the intestinal microbiome in the senescence-accelerated mouse prone 8 strain

(2019) Jianhui Wang et al.   Aging-US

Herbal Formula Fo Shou San Attenuates Alzheimer’s Disease-Related Pathologies via the Gut-Liver-Brain Axis in APP/PS1 Mouse Model of Alzheimer’s Disease

(2019) Jia Lu et al.   Evidence-based Complementary and Alternative Medicine

Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota

(2019) Binyin Li et al.   Alzheimers & Dementia

The microbiome: A target for Alzheimer disease?

(2019) Dong-oh Seo et al.   CELL RESEARCH

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Fecal microbiota transplantation alleviated Alzheimer’s disease-like pathogenesis in APP/PS1 transgenic mice

(2019) Jing Sun et al.   Translational Psychiatry

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild cognitive impairment

(2019) Ravinder Nagpal et al.   EBioMedicine

C‐type lectin‐like receptor 2 and zonulin are associated with mild cognitive impairment and Alzheimer's disease

(2019) Xin Wang et al.   ACTA NEUROLOGICA SCANDINAVICA

Ghrelin in Alzheimer’s disease: Pathologic roles and therapeutic implications

(2019) Seong Gak Jeon et al.   AGEING RESEARCH REVIEWS

Modified Huang-Lian-Jie-Du Decoction Ameliorates Aβ Synaptotoxicity in a Murine Model of Alzheimer’s Disease

(2019) Yan Liu et al.   Oxidative Medicine and Cellular Longevity

Microbiota and the social brain

(2019) Eoin Sherwin et al.   SCIENCE

The Interplay of Diet Quality and Alzheimer’s Disease Genetic Risk Score in Relation to Cognitive Performance Among Urban African Americans

(2019) Sharmin Hossain et al.   Nutrients

A cerebrospinal fluid biosignature for the diagnosis of Alzheimer’s disease

(2019) Tatiana Barichello et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Lactobacilli and bifidobacteria ameliorate memory and learning deficits and oxidative stress in β-amyloid (1–42) injected rats

(2018) Somayeh Athari Nik Azm et al.   Applied Physiology Nutrition and Metabolism

Platelets: Peripheral Biomarkers of Dementia?

(2018) Oluwatomi E.S. Akingbade et al.   JOURNAL OF ALZHEIMERS DISEASE

Gut Microbiota is Altered in Patients with Alzheimer’s Disease

(2018) Zhen-Qian Zhuang et al.   JOURNAL OF ALZHEIMERS DISEASE

Bacteroidetes Neurotoxins and Inflammatory Neurodegeneration

(2018) Yuhai Zhao et al.   MOLECULAR NEUROBIOLOGY

SLAB51 Probiotic Formulation Activates SIRT1 Pathway Promoting Antioxidant and Neuroprotective Effects in an AD Mouse Model

(2018) Laura Bonfili et al.   MOLECULAR NEUROBIOLOGY

A Review on Central Nervous System Effects of Gastrodin

(2018) Yuan Liu et al.   Frontiers in Pharmacology

Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier

(2018) Lesley Hoyles et al.   Microbiome

Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders

(2018) Sigrid Breit et al.   Frontiers in Psychiatry

Can a Bacterial Endotoxin be a Key Factor in the Kinetics of Amyloid Fibril Formation?

(2018) Annalia Asti et al.   JOURNAL OF ALZHEIMERS DISEASE

Periodontal Pathogens and Associated Intrathecal Antibodies in Early Stages of Alzheimer’s Disease

(2018) Oliver Laugisch et al.   JOURNAL OF ALZHEIMERS DISEASE

You are what you eat: diet, health and the gut microbiota

(2018) Niv Zmora et al.   Nature Reviews Gastroenterology & Hepatology

Unhealthy gut, unhealthy brain: The role of the intestinal microbiota in neurodegenerative diseases

(2018) Lindsay Joy Spielman et al.   NEUROCHEMISTRY INTERNATIONAL

A gut-brain neural circuit for nutrient sensory transduction

(2018) Melanie Maya Kaelberer et al.   SCIENCE

The Gut-Brain Axis in Alzheimer’s Disease and Omega-3. A Critical Overview of Clinical Trials

(2018) Francesca La Rosa et al.   Nutrients

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

(2018) Kwangsik Nho et al.   Alzheimers & Dementia

Microbiome–microglia connections via the gut–brain axis

(2018) Reem Abdel-Haq et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder

(2018) Martina Sgritta et al.   NEURON

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

(2018) Nicholas M. Vogt et al.   Alzheimers Research & Therapy

Peripheral inflammatory markers in Alzheimer’s disease: a systematic review and meta-analysis of 175 studies

(2017) Ka Sing P Lai et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Epigenetic Metabolite Acetate Inhibits Class I/II Histone Deacetylases, Promotes Histone Acetylation, and Increases HIV-1 Integration in CD4 + T Cells

(2017) Jean-François Bolduc et al.   JOURNAL OF VIROLOGY

The impact of cellular metabolism on chromatin dynamics and epigenetics

(2017) Michael A. Reid et al.   NATURE CELL BIOLOGY

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

(2017) Annamaria Cattaneo et al.   NEUROBIOLOGY OF AGING

Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration

(2017) Duraisamy Kempuraj et al.   Frontiers in Cellular Neuroscience

Aging Microglia—Phenotypes, Functions and Implications for Age-Related Neurodegenerative Diseases

(2017) Björn Spittau   Frontiers in Aging Neuroscience

The role of microbial amyloid in neurodegeneration

(2017) Robert P. Friedland et al.   PLoS Pathogens

Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

(2017) Yuhai Zhao et al.   Frontiers in Cellular and Infection Microbiology

Expression of the Ghrelin and Neurotensin Systems is Altered in the Temporal Lobe of Alzheimer's Disease Patients

(2017) Manuel D. Gahete et al.   JOURNAL OF ALZHEIMERS DISEASE

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Towards understanding brain-gut-microbiome connections in Alzheimer’s disease

(2016) Rong Xu et al.   BMC Systems Biology

Targeting Tumor Necrosis Factor Alpha for Alzheimer’s Disease

(2016) Boris Decourt et al.   Current Alzheimer Research

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance

(2016) Xianyuan Xiang et al.   EMBO Molecular Medicine

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine

(2016) Xinhua Zhou et al.   Evidence-based Complementary and Alternative Medicine

Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behavior

(2016) Pauline Luczynski et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Synaptopathies: synaptic dysfunction in neurological disorders - A review from students to students

(2016) Katarzyna Lepeta et al.   JOURNAL OF NEUROCHEMISTRY

The complex task of measuring intestinal permeability in basic and clinical science

(2016) H. J. Galipeau et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Gram-negative bacterial molecules associate with Alzheimer disease pathology

(2016) Xinhua Zhan et al.   NEUROLOGY

Gut microbiota induce IGF-1 and promote bone formation and growth

(2016) Jing Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leptin attenuates the detrimental effects of β-amyloid on spatial memory and hippocampal later-phase long term potentiation in rats

(2015) Jia-qing Tong et al.   HORMONES AND BEHAVIOR

DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response

(2015) Li Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gut Microbiota Interacts With Brain Microstructure and Function

(2015) José-Manuel Fernandez-Real et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Leptin and the brain: Influences on brain development, cognitive functioning and psychiatric disorders

(2015) Olivia M. Farr et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Gut microbiota and aging

(2015) P. W. OToole et al.   SCIENCE

Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease

(2015) Marilia S. Albuquerque et al.   Frontiers in Aging Neuroscience

Microbial-generated amyloids and Alzheimer's disease (AD)

(2015) James M. Hill et al.   Frontiers in Aging Neuroscience

Fecal microbiota transplantation: in perspective

(2015) Shaan Gupta et al.   Therapeutic Advances in Gastroenterology

Stress disrupts intestinal mucus barrier in rats via mucin O-glycosylation shift: prevention by a probiotic treatment

(2014) Stéphanie Da Silva et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Changes in Intestinal Glucocorticoid Sensitivity in Early Life Shape the Risk of Epithelial Barrier Defect in Maternal-Deprived Rats

(2014) Nabila Moussaoui et al.   PLoS One

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

The role of pro-inflammatory S100A9 in Alzheimer’s disease amyloid-neuroinflammatory cascade

(2013) Chao Wang et al.   ACTA NEUROPATHOLOGICA

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Ghrelin directly stimulates adult hippocampal neurogenesis: implications for learning and memory

(2013) Endan Li et al.   ENDOCRINE JOURNAL

Endocrine Aspects of Post-traumatic Stress Disorder and Implications for Diagnosis and Treatment

(2013) Nikolaos P. Daskalakis et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Diet rapidly and reproducibly alters the human gut microbiome

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