标题
Advances in pathogenesis and therapeutic strategies for osteoporosis
作者
关键词
-
出版物
PHARMACOLOGY & THERAPEUTICS
Volume 237, Issue -, Pages 108168
出版商
Elsevier BV
发表日期
2022-03-11
DOI
10.1016/j.pharmthera.2022.108168
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Bortezomib Rescues Ovariectomy-Induced Bone Loss via SMURF-Mediated Ubiquitination Pathway
- (2022) Yuepeng Fang et al. Oxidative Medicine and Cellular Longevity
- Capability of core-sheath polyvinyl alcohol- Polycaprolactone emulsion electrospun nanofibrous scaffolds in releasing strontium ranelate for bone regeneration
- (2021) Seyyed Behnam Abdollahi Boraei et al. Biomedical Materials
- Vitamin D and bone health status in beta thalassemia patients—systematic review
- (2021) P.P. Manolopoulos et al. OSTEOPOROSIS INTERNATIONAL
- Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice
- (2021) Leena Sapra et al. Scientific Reports
- Intraperitoneal injection of Desferal® alleviated the age-related bone loss and senescence of bone marrow stromal cells in rats
- (2021) Lingxian Yi et al. Stem Cell Research & Therapy
- Effects of Hydrogen sulfide on the microbiome: From toxicity to therapy
- (2021) Andre G Buret et al. ANTIOXIDANTS & REDOX SIGNALING
- Sulfate transport mutants affect hydrogen sulfide and sulfite production during alcoholic fermentation
- (2021) Michelle E. Walker et al. YEAST
- Hepcidin-induced reduction in iron content and PGC-1β expression negatively regulates osteoclast differentiation to play a protective role in postmenopausal osteoporosis
- (2021) Hui Zhang et al. Aging-US
- Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density
- (2021) Ching-Ti Liu et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Therapeutic potential of iron chelators on osteoporosis and their cellular mechanisms
- (2021) Jian Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Targeting Iron Deficiency in Heart Failure: Existing Evidence and Future Expectations
- (2021) Piotr Ponikowski et al. Circulation-Heart Failure
- Effects of gut microbiota on atherosclerosis through hydrogen sulfide
- (2021) Dan-Dan Gui et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- PAX8-AS1 knockdown facilitates cell growth and inactivates autophagy in osteoblasts via the miR-1252-5p/GNB1 axis in osteoporosis
- (2021) Caiqiang Huang et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- A randomized, controlled trial of once-weekly teriparatide injection versus alendronate in patients at high risk of osteoporotic fracture: primary results of the Japanese Osteoporosis Intervention Trial-05
- (2021) H. Hagino et al. OSTEOPOROSIS INTERNATIONAL
- Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis
- (2021) Yuanyuan Guo et al. Redox Biology
- Hyper-activated platelet lysates prevent glucocorticoid-associated femoral head necrosis by regulating autophagy
- (2021) Zhipeng Huang et al. BIOMEDICINE & PHARMACOTHERAPY
- The Effect of Teriparatide Treatment on the Risk of Fragility Fractures in Postmenopausal Women with Osteoporosis: Results from the Asian and Latin America Fracture Observational Study (ALAFOS)
- (2021) Chung-Hwan Chen et al. CALCIFIED TISSUE INTERNATIONAL
- Iron Deficiency is Associated With More Severe Pulmonary Vascular Disease in Pulmonary Hypertension Caused by Chronic Lung Disease
- (2021) Jasmine Tatah et al. CHEST
- Switching to Denosumab or Bisphosphonates After Completion of Teriparatide Treatment in Women With Severe Postmenopausal Osteoporosis
- (2021) Tomaz Kocjan et al. Endocrine Practice
- Probiotics as a New Regulator for Bone Health: A Systematic Review and Meta-Analysis
- (2021) Hanieh Malmir et al. Evidence-based Complementary and Alternative Medicine
- Iron deficiency exacerbates cisplatin- or rhabdomyolysis-induced acute kidney injury through promoting iron-catalyzed oxidative damage
- (2021) Shifeng Zhao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Exogenous Hydrogen Sulfide Plays an Important Role by Regulating Autophagy in Diabetic-Related Diseases
- (2021) Shuangyu Lv et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Efficacy of romosozumab in patients with osteoporosis on maintenance hemodialysis in Japan; an observational study
- (2021) Motohiko Sato et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Rictor Is a Novel Regulator of TRAF6 / TRAF3 in Osteoclasts
- (2021) Song Xu et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Romosozumab improves lumbar spine bone mass and bone strength parameters relative to alendronate in postmenopausal women: results from the Active‐Controlled Fracture Study in Postmenopausal Women With Osteoporosis at High Risk ( ARCH) trial
- (2021) Jacques P. Brown et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Nuclear scaffold protein p54nrb/NONO facilitates the hypoxia-enhanced progression of hepatocellular carcinoma
- (2021) Mengqin Shen et al. ONCOGENE
- Vitamin A in health care: Suppression of growth and induction of differentiation in cancer cells by vitamin A and its derivatives and their mechanisms of action
- (2021) Noriko Takahashi et al. PHARMACOLOGY & THERAPEUTICS
- Denosumab versus romosozumab for postmenopausal osteoporosis treatment
- (2021) Tomonori Kobayakawa et al. Scientific Reports
- 7,8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis
- (2021) Fan Xue et al. eLife
- Central Administration of Hydrogen Sulfide Donor NaHS Reduces Iba1-Positive Cells in the PVN and Attenuates Rodent Angiotensin II Hypertension
- (2021) Basak Donertas Ayaz et al. Frontiers in Neuroscience
- Tanshinol Alleviates Microcirculation Disturbance and Impaired Bone Formation by Attenuating TXNIP Signaling in GIO Rats
- (2021) Wenxiu Lai et al. Frontiers in Pharmacology
- LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss
- (2021) Fei Liu et al. Redox Biology
- Bone Autophagy: A Potential Way of Exercise-Mediated Meg3/P62/Runx2 Pathway to Regulate Bone Formation in T2DM Mice
- (2021) Xianghe Chen et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Combined Effects of Exercise and Denosumab Treatment on Local Failure in Post-menopausal Osteoporosis–Insights from Bone Remodelling Simulations Accounting for Mineralisation and Damage
- (2021) Javier Martínez-Reina et al. Frontiers in Bioengineering and Biotechnology
- A ROS-responsive, self-immolative and self-reporting hydrogen sulfide donor with multiple biological activities for the treatment of myocardial infarction
- (2021) Mengyun Yao et al. Bioactive Materials
- Present and future scope of recombinant parathyroid hormone therapy in orthopaedics
- (2021) Arnab Sain et al. Journal of Clinical Orthopaedics and Trauma
- Hydrogen sulfide suppresses the proliferation of intestinal epithelial cells through cell cycle arrest
- (2021) Wenxi Xu et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Hydrogen sulfide in ageing, longevity and disease
- (2021) Stephen E. Wilkie et al. BIOCHEMICAL JOURNAL
- Hydrogen sulfide prevents arterial medial calcification in rats with diabetic nephropathy
- (2021) Fang-Zheng Wang et al. BMC Cardiovascular Disorders
- Bone matrix quality in paired iliac bone biopsies from postmenopausal women treated for 12 months with strontium ranelate or alendronate
- (2021) Guillaume Falgayrac et al. BONE
- Calcitonin increases hepatic hepcidin expression through the BMP6 of kidney in mice
- (2021) Yuhua Lei et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Hydrogen sulfide plays a potential alternative for the treatment of metabolic disorders of diabetic cardiomyopathy
- (2021) Nian-Hua Deng et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Urolithin A suppresses RANKL-induced osteoclastogenesis and postmenopausal osteoporosis by, suppresses inflammation and downstream NF-κB activated pyroptosis pathways
- (2021) Huaqiang Tao et al. PHARMACOLOGICAL RESEARCH
- Osteoporosis therapies and their mechanisms of action (Review)
- (2021) Beomchang Kim et al. Experimental and Therapeutic Medicine
- Rhizoma drynariae total flavonoids combined with calcium carbonate ameliorates bone loss in experimentally induced Osteoporosis in rats via the regulation of Wnt3a/β-catenin pathway
- (2021) Yimei Hu et al. Journal of Orthopaedic Surgery and Research
- Zinc oxide nanosphere for hydrogen sulfide scavenging and ferroptosis of colorectal cancer
- (2021) Xiang Pan et al. JOURNAL OF NANOBIOTECHNOLOGY
- Effect of Intermittent Fasting on Glucose Homeostasis and Bone Remodeling in Glucocorticoid-Induced Osteoporosis Rat Model
- (2021) Majed G. Alrowaili et al. Journal of Bone Metabolism
- The Osteocyte: New Insights
- (2020) Alexander G. Robling et al. Annual Review of Physiology
- Hydrogen Sulfide Positively Regulates Abscisic Acid Signaling through Persulfidation of SnRK2.6 in Guard Cells
- (2020) Sisi Chen et al. Molecular Plant
- PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells
- (2020) Mingcan Yu et al. Nature Communications
- Effects of Synbiotic Supplement on Human Gut Microbiota, Body Composition and Weight Loss in Obesity
- (2020) Igor N. Sergeev et al. Nutrients
- The shared KEGG pathways between icariin-targeted genes and osteoporosis
- (2020) Tao Yu et al. Aging-US
- Gut microbiota and metabolite alterations associated with reduced bone mineral density or bone metabolic indexes in postmenopausal osteoporosis
- (2020) Jianquan He et al. Aging-US
- Parathyroid hormone–dependent bone formation requires butyrate production by intestinal microbiota
- (2020) Jau-Yi Li et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of cellular senescence in ageing and endocrine disease
- (2020) Sundeep Khosla et al. Nature Reviews Endocrinology
- Role of nitroxyl (HNO) in cardiovascular system: From biochemistry to pharmacology
- (2020) Hai-Jian Sun et al. PHARMACOLOGICAL RESEARCH
- Effects of an orally supplemented probiotic on the autophagy protein LC3 and Beclin1 in placentas undergoing spontaneous delivery during normal pregnancy
- (2020) Ping Yang et al. BMC Pregnancy and Childbirth
- The Senolytic Drug Navitoclax (ABT-263) Causes Trabecular Bone Loss and Impaired Osteoprogenitor Function in Aged Mice
- (2020) Anuj K. Sharma et al. Frontiers in Cell and Developmental Biology
- Association of gut microbiota composition and function with an aged rat model of senile osteoporosis using 16S rRNA and metagenomic sequencing analysis
- (2020) Sicong Ma et al. Aging-US
- History of alendronate
- (2020) Steven R. Cummings et al. BONE
- Gut Microbiota and Cardiovascular Disease
- (2020) Marco Witkowski et al. CIRCULATION RESEARCH
- Senolytic drugs: from discovery to translation
- (2020) J. L. Kirkland et al. JOURNAL OF INTERNAL MEDICINE
- Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization
- (2020) Katalin Éva Sikura et al. Journal of Advanced Research
- Eucommia ulmoides leaf extract alters gut microbiota composition, enhances short‐chain fatty acids production, and ameliorates osteoporosis in the senescence‐accelerated mouse P6 (SAMP6) model
- (2020) Xin Zhao et al. Food Science & Nutrition
- Lactobacillus Fermentum ZS40 prevents secondary osteoporosis in Wistar Rat
- (2020) Xinhong Liu et al. Food Science & Nutrition
- Targeting autophagy in osteoporosis: From pathophysiology to potential therapy
- (2020) Xu Li et al. AGEING RESEARCH REVIEWS
- Lactobacillus Plantarum HFY15 Helps Prevent Retinoic Acid-Induced Secondary Osteoporosis in Wistar Rats
- (2020) Xinhong Liu et al. Evidence-based Complementary and Alternative Medicine
- Gut microbiota in human metabolic health and disease
- (2020) Yong Fan et al. NATURE REVIEWS MICROBIOLOGY
- Osteoblast-Osteoclast Communication and Bone Homeostasis
- (2020) Jung-Min Kim et al. Cells
- Metabolism and Metabolic Disorders and the Microbiome: The Intestinal Microbiota Associated With Obesity, Lipid Metabolism, and Metabolic Health—Pathophysiology and Therapeutic Strategies
- (2020) Judith Aron-Wisnewsky et al. GASTROENTEROLOGY
- Development of a novel polysaccharide-based iron oxide nanoparticle to prevent iron accumulation-related osteoporosis by scavenging reactive oxygen species
- (2020) Pengjun Yu et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Management of Iron Overload in Beta-Thalassemia Patients: Clinical Practice Update Based on Case Series
- (2020) Valeria Maria Pinto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of Gut Microbiota in the Skeletal Response to PTH
- (2020) Roberto Pacifici JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Iron deficiency
- (2020) Sant-Rayn Pasricha et al. LANCET
- Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis
- (2020) Hongdong Ma et al. Oxidative Medicine and Cellular Longevity
- The Intestinal Microbiota and Colorectal Cancer
- (2020) Yiwen Cheng et al. Frontiers in Immunology
- Glutamine metabolite α-ketoglutarate acts as an epigenetic co-factor to interfere with osteoclast differentiation
- (2020) Sangyong Lee et al. BONE
- Dietary Fructooligosaccharide and Glucomannan Alter Gut Microbiota and Improve Bone Metabolism in Senescence-Accelerated Mouse
- (2019) Kenichi Tanabe et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Osteoporosis
- (2019) Juliet E Compston et al. LANCET
- Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans
- (2019) JoshuaN Farr et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The Effect of Multispecies Probiotic Supplementation on Iron Status in Rats
- (2019) Katarzyna Skrypnik et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
- (2019) Allyson K. Palmer et al. AGING CELL
- Sirtuins and FoxOs in osteoporosis and osteoarthritis
- (2019) Maria Almeida et al. BONE
- The Case for an Estrogen-iron Axis in Health and Disease
- (2019) Mawieh Hamad et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- Beclin1 modulates bone homeostasis by regulating osteoclast and chondrocyte differentiation
- (2019) Atsushi Arai et al. JOURNAL OF BONE AND MINERAL RESEARCH
- α-Ketoglutarate inhibits autophagy
- (2019) Elisa Elena Baracco et al. Aging-US
- How many bones? Every bone in my body
- (2019) Paul E. Neumann et al. CLINICAL ANATOMY
- Grapefruit juice exerts anti-osteoporotic activities in a prednisolone-induced osteoporosis rat femoral fracture model, possibly via the RANKL/OPG axis
- (2019) Eslam Muhammad Bastawy et al. CYTOTECHNOLOGY
- Gut microbiota and obesity-associated osteoarthritis
- (2019) Y. Liu et al. OSTEOARTHRITIS AND CARTILAGE
- Alpha ketoglutarate exerts a pro-osteogenic effect in osteoblast cell lines through activation of JNK and mTOR/S6K1/S6 signaling pathways
- (2019) Aleksandra Żurek et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Cellular senescence: at the nexus between ageing and diabetes
- (2019) Allyson K. Palmer et al. DIABETOLOGIA
- Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis
- (2019) Xudong Wang et al. MOLECULAR MEDICINE
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
- (2019) LaTonya J. Hickson et al. EBioMedicine
- Hydrogen Sulfide in Bone Tissue Regeneration and Repair: State of the Art and New Perspectives
- (2019) Laura Gambari et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The gut microbiome in neurological disorders
- (2019) John F Cryan et al. LANCET NEUROLOGY
- Involvement of the Gut Microbiota and Barrier Function in Glucocorticoid‐Induced Osteoporosis
- (2019) Jonathan D Schepper et al. JOURNAL OF BONE AND MINERAL RESEARCH
- eIF2α signaling regulates autophagy of osteoblasts and the development of osteoclasts in OVX mice
- (2019) Jie Li et al. Cell Death & Disease
- A Systematic Review and Meta-Analysis on the Effects of Probiotic Species on Iron Absorption and Iron Status
- (2019) Susan C. Vonderheid et al. Nutrients
- Autophagy as a target for glucocorticoid-induced osteoporosis therapy
- (2018) Gengyang Shen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Phosphorylation of extracellular bone matrix proteins and its contribution to bone fragility
- (2018) Grażyna E. Sroga et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Effect of dietary α -ketoglutarate and allicin supplementation on the composition and diversity of the cecal microbial community in growing pigs
- (2018) Shaojuan Liu et al. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
- Osteoprotegrin interacts with biomarkers and cytokines that have roles in osteoporosis, skin fibrosis, and vasculopathy in systemic sclerosis: a potential multifaceted relationship between OPG/RANKL/TRAIL and Wnt inhibitors
- (2018) Ali Taylan et al. Modern Rheumatology
- Senolytics improve physical function and increase lifespan in old age
- (2018) Ming Xu et al. NATURE MEDICINE
- Mechanism and medical implications of mammalian autophagy
- (2018) Ivan Dikic et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Regulation of Bone Remodeling by Parathyroid Hormone
- (2018) Marc N. Wein et al. Cold Spring Harbor Perspectives in Medicine
- Mechanically induced autophagy is associated with ATP metabolism and cellular viability in osteocytes in vitro
- (2018) Bingbing Zhang et al. Redox Biology
- The bone remodelling cycle
- (2018) JS Kenkre et al. ANNALS OF CLINICAL BIOCHEMISTRY
- Experimental research into the potential therapeutic effect of GYY4137 on Ovariectomy-induced osteoporosis
- (2018) Zhong-Shi Xu et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Identification of the key excreted molecule by Lactobacillus fermentum related to host iron absorption
- (2017) Ana González et al. FOOD CHEMISTRY
- Association Between Gut Microbiota and Bone Health: Potential Mechanisms and Prospective
- (2017) Yuan-Cheng Chen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Role of autophagy in tumor necrosis factor-α-induced apoptosis of osteoblast cells
- (2017) Liwen Zheng et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Effects of a Multispecies Probiotic Supplement on Bone Health in Osteopenic Postmenopausal Women: A Randomized, Double-blind, Controlled Trial
- (2017) Sadegh Jafarnejad et al. JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
- Gut microbiota and malnutrition
- (2017) Matthieu Million et al. MICROBIAL PATHOGENESIS
- Targeting cellular senescence prevents age-related bone loss in mice
- (2017) Joshua N Farr et al. NATURE MEDICINE
- Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
- (2017) Kenneth G. Saag et al. NEW ENGLAND JOURNAL OF MEDICINE
- The effect of icariin on bone metabolism and its potential clinical application
- (2017) Z. Wang et al. OSTEOPOROSIS INTERNATIONAL
- Iron Deficiency Anemia as a Risk Factor for Osteoporosis in Taiwan: A Nationwide Population-Based Study
- (2017) Mei-Lien Pan et al. Nutrients
- Alpha-ketoglutarate (AKG) lowers body weight and affects intestinal innate immunity through influencing intestinal microbiota
- (2017) Shuai Chen et al. Oncotarget
- Intestinal microbiota: a potential target for the treatment of postmenopausal osteoporosis
- (2017) Xin Xu et al. Bone Research
- Cellular Senescence: A Translational Perspective
- (2017) James L. Kirkland et al. EBioMedicine
- Alpha-Ketoglutarate as a Molecule with Pleiotropic Activity: Well-Known and Novel Possibilities of Therapeutic Use
- (2016) Barbara Zdzisińska et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- BA321, a novel carborane analog that binds to androgen and estrogen receptors, acts as a new selective androgen receptor modulator of bone in male mice
- (2016) Kenta Watanabe et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Aging and adipose tissue: potential interventions for diabetes and regenerative medicine
- (2016) Allyson K. Palmer et al. EXPERIMENTAL GERONTOLOGY
- Results of geriatric distal radius fractures treated by intramedullary fixation
- (2016) Steffi S.I. Falk et al. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
- Iron Homeostasis in Health and Disease
- (2016) Raffaella Gozzelino et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Characterization of a Relatively Malignant Form of Osteopetrosis Caused by a Novel Mutation in thePLEKHM1Gene
- (2016) Tao Bo et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Links Between the Microbiome and Bone
- (2016) Christopher J Hernandez et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Osteoblast Malfunction Caused by Cell Stress Response to Procollagen Misfolding in α2(I)-G610C Mouse Model of Osteogenesis Imperfecta
- (2016) Lynn S Mirigian et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Identification of Senescent Cells in the Bone Microenvironment
- (2016) Joshua N Farr et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics
- (2016) Jau-Yi Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Romosozumab Treatment in Postmenopausal Women with Osteoporosis
- (2016) Felicia Cosman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Osteonecrosis of the jaw (ONJ) and atypical femoral fracture (AFF) in an osteoporotic patient chronically treated with bisphosphonates
- (2016) A. Sánchez et al. OSTEOPOROSIS INTERNATIONAL
- Teriparatide for osteoporosis: importance of the full course
- (2016) R. Lindsay et al. OSTEOPOROSIS INTERNATIONAL
- Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
- (2016) Reut Yosef et al. Nature Communications
- The Value of Osteopontin in the Assessment of Bone Mineral Density Status in Postmenopausal Women
- (2016) Daniela Fodor et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Gut Microbiota Conversion of Dietary Ellagic Acid into Bioactive Phytoceutical Urolithin A Inhibits Heme Peroxidases
- (2016) Piu Saha et al. PLoS One
- Lactobacillus reuteri 6475 Increases Bone Density in Intact Females Only under an Inflammatory Setting
- (2016) Fraser L. Collins et al. PLoS One
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss
- (2015) Neng-Yu Lin et al. ANNALS OF THE RHEUMATIC DISEASES
- An overview of molecular basis of iron metabolism regulation and the associated pathologies
- (2015) Bruno Silva et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Idiopathic Juvenile Osteoporosis: Clinical Experience from a Single Centre and Screening of LRP5 and LRP6 Genes
- (2015) Roberto Franceschi et al. CALCIFIED TISSUE INTERNATIONAL
- Long Noncoding RNAs in Cardiovascular Diseases
- (2015) S. Uchida et al. CIRCULATION RESEARCH
- The role of the gut microbiome in the healthy adult status
- (2015) Valeria D’Argenio et al. CLINICA CHIMICA ACTA
- Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity
- (2015) Allyson K. Palmer et al. DIABETES
- Clinical strategies and animal models for developing senolytic agents
- (2015) James L. Kirkland et al. EXPERIMENTAL GERONTOLOGY
- Diosgenin prevents bone loss on retinoic acid-induced osteoporosis in rats
- (2015) S. Zhao et al. IRISH JOURNAL OF MEDICAL SCIENCE
- The Effect of 6 versus 9 Years of Zoledronic Acid Treatment in Osteoporosis: A Randomized Second Extension to the HORIZON-Pivotal Fracture Trial (PFT)
- (2015) Dennis M. Black et al. JOURNAL OF BONE AND MINERAL RESEARCH
- A Randomized, Double-Blind Phase 2 Clinical Trial of Blosozumab, a Sclerostin Antibody, in Postmenopausal Women with Low Bone Mineral Density
- (2015) Robert R. Recker et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Effects of the gut microbiota on bone mass
- (2015) Claes Ohlsson et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Molecular aspects of intestinal calcium absorption
- (2015) Gabriela Diaz de Barboza et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Microbial Degradation of Whole-Grain Complex Carbohydrates and Impact on Short-Chain Fatty Acids and Health
- (2015) Knud Erik Bach Knudsen Advances in Nutrition
- Probiotics (Bifidobacterium longum) Increase Bone Mass Density and UpregulateSparcandBmp-2Genes in Rats with Bone Loss Resulting from Ovariectomy
- (2015) Kolsoom Parvaneh et al. Biomed Research International
- Dimethyl α-ketoglutarate inhibits maladaptive autophagy in pressure overload-induced cardiomyopathy
- (2014) Guillermo Mariño et al. Autophagy
- Anti-osteopontin monoclonal antibody prevents ovariectomy-induced osteoporosis in mice by promotion of osteoclast apoptosis
- (2014) Bo Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hydrogen sulphide protects against NSAID-enteropathy through modulation of bile and the microbiota
- (2014) Rory W Blackler et al. BRITISH JOURNAL OF PHARMACOLOGY
- Alterations in Collagen and Mineral Nanostructure Observed in Osteoporosis and Pharmaceutical Treatments Using Simultaneous Small- and Wide-Angle X-ray Scattering
- (2014) Alvin S. Acerbo et al. CALCIFIED TISSUE INTERNATIONAL
- Geroscience: Linking Aging to Chronic Disease
- (2014) Brian K. Kennedy et al. CELL
- Specialized Metabolites from the Microbiome in Health and Disease
- (2014) Gil Sharon et al. Cell Metabolism
- Hydrogen Sulfide Maintains Mesenchymal Stem Cell Function and Bone Homeostasis via Regulation of Ca2+ Channel Sulfhydration
- (2014) Yi Liu et al. Cell Stem Cell
- Combined effects of collagen type I alpha1 (COL1A1) Sp1 polymorphism and osteoporosis risk factors on bone mineral density in Turkish postmenopausal women
- (2014) Ozlem Kurt-Sirin et al. GENE
- Autophagy—a key player in cellular and body metabolism
- (2014) Kook Hwan Kim et al. Nature Reviews Endocrinology
- Romosozumab in Postmenopausal Women with Low Bone Mineral Density
- (2014) Michael R. McClung et al. NEW ENGLAND JOURNAL OF MEDICINE
- FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation
- (2014) Shoshana M. Bartell et al. Nature Communications
- Common Polymorphism in theLRP5Gene May Increase the Risk of Bone Fracture and Osteoporosis
- (2014) Guang-Yue Xu et al. Biomed Research International
- The osteocyte as a therapeutic target in the treatment of osteoporosis
- (2014) Gaël Y. Rochefort Therapeutic Advances in Musculoskeletal Disease
- Boning up on autophagy
- (2013) Irving M Shapiro et al. Autophagy
- Involvement of WNT/β-catenin Signaling in the Treatment of Osteoporosis
- (2013) Maurizio Rossini et al. CALCIFIED TISSUE INTERNATIONAL
- Osteoclast-Derived Coupling Factors in Bone Remodeling
- (2013) Kim Henriksen et al. CALCIFIED TISSUE INTERNATIONAL
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Historical landmarks of autophagy research
- (2013) Yoshinori Ohsumi CELL RESEARCH
- Chaperone-mediated autophagy: roles in disease and aging
- (2013) Ana Maria Cuervo et al. CELL RESEARCH
- New Insights Into the Role of Sequestosome 1/p62 Mutant Proteins in the Pathogenesis of Paget's Disease of Bone
- (2013) Sarah L. Rea et al. ENDOCRINE REVIEWS
- Cytochromes P450: Roles in Diseases
- (2013) Irina A. Pikuleva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation
- (2013) Fei Liu et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Probiotic use decreases intestinal inflammation and increases bone density in healthy male but not female mice
- (2013) Laura R. McCabe et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Oral Supplementation With ProbioticL. reuteriNCIMB 30242 Increases Mean Circulating 25-Hydroxyvitamin D: A Post Hoc Analysis of a Randomized Controlled Trial
- (2013) Mitchell L. Jones et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation
- (2013) Yan Xiu et al. JOURNAL OF CLINICAL INVESTIGATION
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- (2013) Tamara Tchkonia et al. JOURNAL OF CLINICAL INVESTIGATION
- Genotyping and Genomic Profiling of Non–Small-Cell Lung Cancer: Implications for Current and Future Therapies
- (2013) Tianhong Li et al. JOURNAL OF CLINICAL ONCOLOGY
- Prevention and treatment of postmenopausal osteoporosis
- (2013) Sri Harsha Tella et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Effect of the cathepsin K inhibitor odanacatib administered once weekly on bone mineral density in Japanese patients with osteoporosis—a double-blind, randomized, dose-finding study
- (2013) T. Nakamura et al. OSTEOPOROSIS INTERNATIONAL
- An evaluation of the Fracture Risk Assessment Tool (FRAX®) as an indicator of treatment efficacy: the effects of bazedoxifene and raloxifene on vertebral, nonvertebral, and all clinical fractures as a function of baseline fracture risk assessed by FRAX®
- (2013) J.-M. Kaufman et al. OSTEOPOROSIS INTERNATIONAL
- Probiotic Mechanisms of Action
- (2012) Miriam Bermudez-Brito et al. ANNALS OF NUTRITION AND METABOLISM
- Autophagy regulates TNFα-mediated joint destruction in experimental arthritis
- (2012) Neng-Yu Lin et al. ANNALS OF THE RHEUMATIC DISEASES
- A Comparison of the Biological Activities of Human Osteoblast hFOB1.19 Between Iron Excess and Iron Deficiency
- (2012) Guo-yang Zhao et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- A comparison of survival outcomes and side effects of toremifene or tamoxifen therapy in premenopausal estrogen and progesterone receptor positive breast cancer patients: a retrospective cohort study
- (2012) Ran Gu et al. BMC CANCER
- Anti-osteopenic effect of alpha-ketoglutarate sodium salt in ovariectomized rats
- (2012) Radoslaw Piotr Radzki et al. JOURNAL OF BONE AND MINERAL METABOLISM
- The gut microbiota regulates bone mass in mice
- (2012) Klara Sjögren et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Iron homeostasis in osteoporosis and its clinical implications
- (2012) G. F. Li et al. OSTEOPOROSIS INTERNATIONAL
- Bone Cell Autophagy Is Regulated by Environmental Factors
- (2011) Adam M. Zahm et al. CELLS TISSUES ORGANS
- Essential but toxic: Controlling the flux of iron in the body
- (2011) Gregory J Anderson et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Building strong bones: molecular regulation of the osteoblast lineage
- (2011) Fanxin Long NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Glucocorticoid-Induced Bone Disease
- (2011) Robert S. Weinstein NEW ENGLAND JOURNAL OF MEDICINE
- Bone loss caused by iron overload in a murine model: importance of oxidative stress
- (2010) J. Tsay et al. BLOOD
- Osteoblast physiology in normal and pathological conditions
- (2010) Anna Neve et al. CELL AND TISSUE RESEARCH
- Increased serum osteopontin is a risk factor for osteoporosis in menopausal women
- (2010) I.-C. Chang et al. OSTEOPOROSIS INTERNATIONAL
- Disruption of PTH Receptor 1 in T Cells Protects against PTH-Induced Bone Loss
- (2010) Hesham Tawfeek et al. PLoS One
- Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity
- (2010) C. A. Whitehouse et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Collagen Structure and Stability
- (2009) Matthew D. Shoulders et al. Annual Review of Biochemistry
- The molecular mechanism behind bone remodelling: a review
- (2009) Peter Proff et al. Clinical Oral Investigations
- Autophagy mediates the mitotic senescence transition
- (2009) A. R.J. Young et al. GENES & DEVELOPMENT
- Synthesis, characterization of strontium-bile acid salts and their bioactivity vs. the anti-osteoporosis drug strontium ranelate
- (2009) Paola Bergamini et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- A crucial role for adipose tissue p53 in the regulation of insulin resistance
- (2009) Tohru Minamino et al. NATURE MEDICINE
- Functions and Regulatory Mechanisms of Gq-Signaling Pathways
- (2009) Norikazu Mizuno et al. NEUROSIGNALS
- Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
- (2009) Steven R. Cummings et al. NEW ENGLAND JOURNAL OF MEDICINE
- Benefit–risk assessment of vitamin D supplementation
- (2009) H. A. Bischoff-Ferrari et al. OSTEOPOROSIS INTERNATIONAL
- Depression as a risk factor for osteoporosis
- (2009) Giovanni Cizza et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- T Cells Potentiate PTH-Induced Cortical Bone Loss through CD40L Signaling
- (2008) Yuhao Gao et al. Cell Metabolism
- Probiotic Lactobacillus reuteri suppress proinflammatory cytokines via c-Jun
- (2008) Yea Ping Lin et al. INFLAMMATORY BOWEL DISEASES
- Bone Disease in Thalassemia: A Frequent and Still Unresolved Problem
- (2008) Maria G Vogiatzi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study
- (2008) JB Richards et al. LANCET
- Multiple Genetic Loci for Bone Mineral Density and Fractures
- (2008) Unnur Styrkarsdottir et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intestinal bile acid physiology and pathophysiology
- (2008) Olga Martínez-Augustin et al. WORLD JOURNAL OF GASTROENTEROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation