Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation

The autophagy geneATG5plays an essential role in B lymphocyte development

(2014) Brian C. Miller et al.   Autophagy

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

FIP200 is required for maintenance and differentiation of postnatal neural stem cells

(2013) Chenran Wang et al.   NATURE NEUROSCIENCE

Autophagy: A new player in skeletal maintenance?

(2012) Lynne J Hocking et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Selective autophagy in the maintenance of cellular homeostasis in aging organisms

(2011) Vanessa M. Hubbard et al.   BIOGERONTOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Autophagy in mineralizing tissues: Microenvironmental perspectives

(2011) Vickram Srinivas et al.   CELL CYCLE

Bone Cell Autophagy Is Regulated by Environmental Factors

(2011) Adam M. Zahm et al.   CELLS TISSUES ORGANS

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

Glucocorticoid dose determines osteocyte cell fate

(2011) Junjing Jia et al.   FASEB JOURNAL

Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

(2011) H. Wei et al.   GENES & DEVELOPMENT

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

(2011) Monika Mortensen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Suppression of Autophagy by FIP200 Deletion Impairs DNA Damage Repair and Increases Cell Death upon Treatments with Anticancer Agents

(2011) H. Bae et al.   MOLECULAR CANCER RESEARCH

Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment

(2011) J. B. Stokes et al.   MOLECULAR CANCER THERAPEUTICS

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

(2011) M. Narita et al.   SCIENCE

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

(2010) F. Liu et al.   BLOOD

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

The direct examination of three-dimensional bone architecture in vitro by computed tomography

(2010) Lee A. Feldkamp et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD

(2010) Lishu Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Glucocorticoid-induced autophagy in osteocytes

(2010) Xuechun Xia et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The regulation-of-autophagy pathway may influence Chinese stature variation: evidence from elder adults

(2010) Feng Pan et al.   JOURNAL OF HUMAN GENETICS

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

(2010) Patricia Spilman et al.   PLoS One

Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity

(2010) C. A. Whitehouse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

What old means to bone

(2010) Stavros C. Manolagas et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Identification ofAtg5-dependent transcriptional changes and increases in mitochondrial mass inAtg5-deficient T lymphocytes

(2009) Linda M. Stephenson et al.   Autophagy

Targeted deletion ofautophagy-related 5(atg5) impairs adipogenesis in a cellular model and in mice

(2009) Rebecca Baerga et al.   Autophagy

Role of ULK-FIP200 complex in mammalian autophagy: FIP200, a counterpart of yeast Atg17?

(2009) Taichi Hara et al.   Autophagy

Beam hardening artifacts in micro-computed tomography scanning can be reduced by X-ray beam filtration and the resulting images can be used to accurately measure BMD

(2009) Jeffrey A. Meganck et al.   BONE

Neural-specific Deletion of FIP200 Leads to Cerebellar Degeneration Caused by Increased Neuronal Death and Axon Degeneration

(2009) Chun-Chi Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Is Essential for Mitochondrial Clearance in Mature T Lymphocytes

(2009) H. H. Pua et al.   JOURNAL OF IMMUNOLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

(2009) M. Mortensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis

(2009) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteopenia in transgenic mice with osteoblast-targeted expression of the inducible cAMP early repressor

(2008) Taranpreet K. Chandhoke et al.   BONE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death

(2008) Francesco Cecconi et al.   DEVELOPMENTAL CELL

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

Essential role for Nix in autophagic maturation of erythroid cells

(2008) Hector Sandoval et al.   NATURE

Autophagy Is Essential for Preimplantation Development of Mouse Embryos

(2008) S. Tsukamoto et al.   SCIENCE

FIP200, a key signaling node to coordinately regulate various cellular processes

(2007) Boyi Gan et al.   CELLULAR SIGNALLING