Targeting Gut Microbiota With Natural Polysaccharides: Effective Interventions Against High-Fat Diet-Induced Metabolic Diseases

SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection

(2022) Paul Feuerstadt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides

(2022) Lucelia Cabral et al.   Nature Communications

The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer’s disease: A narrative review

(2022) Emma Aaldijk et al.   AGEING RESEARCH REVIEWS

Study on fecal fermentation characteristics of aloe polysaccharides in vitro and their predictive modeling

(2021) Chang Liu et al.   CARBOHYDRATE POLYMERS

Suppression of obesity and inflammation by polysaccharide from sporoderm-broken spore of Ganoderma lucidum via gut microbiota regulation

(2021) Tingting Sang et al.   CARBOHYDRATE POLYMERS

High-fiber diet mitigates maternal obesity-induced cognitive and social dysfunction in the offspring via gut-brain axis

(2021) Xiaoning Liu et al.   Cell Metabolism

SIRT2 Prevents Liver Steatosis and Metabolic Disorders via Deacetylation of HNF4α

(2021) Huihui Ren et al.   HEPATOLOGY

Multiomics Approach to Explore the Amelioration Mechanisms of Glucomannans on the Metabolic Disorder of Type 2 Diabetic Rats

(2021) Haihong Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lycium barbarum polysaccharide combined with aerobic exercise ameliorated nonalcoholic fatty liver disease through restoring gut microbiota, intestinal barrier and inhibiting hepatic inflammation

(2021) Lu-Lu Gao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Sirtuins: To Be or Not To Be in Diabetic Cardiomyopathy

(2021) Xavier Palomer et al.   TRENDS IN MOLECULAR MEDICINE

Dietary Strategies for Management of Metabolic Syndrome: Role of Gut Microbiota Metabolites

(2021) Sonia Croci et al.   Nutrients

Natural-Derived Polysaccharides From Plants, Mushrooms, and Seaweeds for the Treatment of Inflammatory Bowel Disease

(2021) Cailan Li et al.   Frontiers in Pharmacology

Plant/algal polysaccharides extracted by microwave: A review on hypoglycemic, hypolipidemic, prebiotic, and immune-stimulatory effect

(2021) Monirsadat Mirzadeh et al.   CARBOHYDRATE POLYMERS

Gut-microbiota-targeted diets modulate human immune status

(2021) Hannah C. Wastyk et al.   CELL

Low-molecular alginate improved diet-induced obesity and metabolic syndrome through modulating the gut microbiota in BALB/c mice

(2021) Weiyun Zheng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Walnut green husk polysaccharides prevent obesity, chronic inflammatory responses, nonalcoholic fatty liver disease and colonic tissue damage in high-fat diet fed rats

(2021) Guoliang Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Microalgae polysaccharides ameliorates obesity in association with modulation of lipid metabolism and gut microbiota in high-fat-diet fed C57BL/6 mice

(2021) Wei Guo et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Recent Progress in Metabolic Syndrome Research and Therapeutics

(2021) Ting-Wei Kao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Composition-Activity Relationships of Polysaccharides from Saccharina japonica in Regulating Gut Microbiota in Short-Term High-Fat Diet-Fed Mice

(2021) Songze Ke et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

NAFLD-driven HCC: Safety and efficacy of current and emerging treatment options

(2021) Friedrich Foerster et al.   JOURNAL OF HEPATOLOGY

The prevalence and risk factors of urinary incontinence among women with type 2 diabetes in the north West Bank: a cross-sectional study

(2021) Zaher Nazzal et al.   LANCET

Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade

(2021) Miles C. Andrews et al.   NATURE MEDICINE

Engineering islets from stem cells for advanced therapies of diabetes

(2021) Johanna Siehler et al.   NATURE REVIEWS DRUG DISCOVERY

The genetics of obesity: from discovery to biology

(2021) Ruth J. F. Loos et al.   NATURE REVIEWS GENETICS

Dietary fiber‐derived short‐chain fatty acids: A potential therapeutic target to alleviate obesity‐related nonalcoholic fatty liver disease

(2021) Shumin Zhang et al.   Obesity Reviews

Effect of Lycium barbarum polysaccharide supplementation in non-alcoholic fatty liver disease patients: study protocol for a randomized controlled trial

(2021) Lu-Lu Gao et al.   Trials

Impact of Gut Microbiota and Microbiota-Related Metabolites on Hyperlipidemia

(2021) Xiaokang Jia et al.   Frontiers in Cellular and Infection Microbiology

Supplementation With Lycium barbarum Polysaccharides Reduce Obesity in High-Fat Diet-Fed Mice by Modulation of Gut Microbiota

(2021) Mei Yang et al.   Frontiers in Microbiology

Glycosaminoglycan from Ostrea rivularis attenuates hyperlipidemia and regulates gut microbiota in high‐cholesterol diet‐fed zebrafish

(2021) Yan Kong et al.   Food Science & Nutrition

Gut Microbiome and Metabolome Profiles Associated with High-Fat Diet in Mice

(2021) Jae-Kwon Jo et al.   Metabolites

Anti-Hyperlipidemia and Gut Microbiota Community Regulation Effects of Selenium-Rich Cordyceps militaris Polysaccharides on the High-Fat Diet-Fed Mice Model

(2021) Minglei Yu et al.   Foods

Polysaccharides Obtained from Cordyceps militaris Alleviate Hyperglycemia by Regulating Gut Microbiota in Mice Fed a High-Fat/Sucrose Diet

(2021) Bao-Hong Lee et al.   Foods

Coix seed polysaccharides alleviate type 2 diabetes mellitus via gut microbiota-derived short-chain fatty acids activation of IGF1/PI3K/AKT signaling

(2021) Ting Xia et al.   FOOD RESEARCH INTERNATIONAL

Obesity management as a primary treatment goal for type 2 diabetes: time to reframe the conversation

(2021) Ildiko Lingvay et al.   LANCET

Soluble Polysaccharide Derived from Laminaria japonica Attenuates Obesity-Related Nonalcoholic Fatty Liver Disease Associated with Gut Microbiota Regulation

(2021) Yiping Zhang et al.   Marine Drugs

Insights into the molecular targets and emerging pharmacotherapeutic interventions for nonalcoholic fatty liver disease

(2021) Chander K. Negi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The human microbiome encodes resistance to the antidiabetic drug acarbose

(2021) Jared Balaich et al.   NATURE

Multifaced role of protein deacetylase sirtuins in neurodegenerative disease

(2021) Rohan Gupta et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Lactobacillus acidophilus ameliorates obesity in mice through modulation of gut microbiota dysbiosis and intestinal permeability

(2021) Yongbo Kang et al.   PHARMACOLOGICAL RESEARCH

Mulberry leaf polysaccharides ameliorate obesity through activation of brown adipose tissue and modulation of the gut microbiota in high-fat diet fed mice

(2021) Ruilin Li et al.   Food & Function

Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota

(2021) Yingchun Zhao et al.   Scientific Reports

Dietary Polysaccharide from Enteromorpha clathrata Attenuates Obesity and Increases the Intestinal Abundance of Butyrate-Producing Bacterium, Eubacterium xylanophilum, in Mice Fed a High-Fat Diet

(2021) Jiali Wei et al.   Polymers

COVID-19 and metabolic disease: mechanisms and clinical management

(2021) Charlotte Steenblock et al.   Lancet Diabetes & Endocrinology

Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut

(2021) Martin F. Laursen et al.   Nature Microbiology

Sequential Extraction, Characterization, and Analysis of Pumpkin Polysaccharides for Their Hypoglycemic Activities and Effects on Gut Microbiota in Mice

(2021) Hui-qing Wu et al.   Frontiers in Nutrition

The Antiviral Activity of Bacterial, Fungal, and Algal Polysaccharides as Bioactive Ingredients: Potential Uses for Enhancing Immune Systems and Preventing Viruses

(2021) Worraprat Chaisuwan et al.   Frontiers in Nutrition

Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients

(2020) Julie Rodriguez et al.   GUT

Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

(2020) Ikuo Kimura et al.   SCIENCE

Considering gut microbiota in treatment of type 2 diabetes mellitus

(2020) Aneseh Adeshirlarijaney et al.   Gut Microbes

Profile of the gut microbiota of adults with obesity: a systematic review

(2020) Louise Crovesy et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Beneficial effects of flaxseed polysaccharides on metabolic syndrome via gut microbiota in high-fat diet fed mice

(2020) Chen Yang et al.   FOOD RESEARCH INTERNATIONAL

Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization

(2020) Tao Zuo et al.   GASTROENTEROLOGY

Potential Beneficial Actions of Fucoidan in Brain and Liver Injury, Disease, and Intoxication—Potential Implication of Sirtuins

(2020) Jasmina Dimitrova-Shumkovska et al.   Marine Drugs

Polysaccharide extracted from WuGuChong reduces high-fat diet-induced obesity in mice by regulating the composition of intestinal microbiota

(2020) Wendong Wang et al.   Nutrition & Metabolism

The Firmicutes/Bacteroidetes Ratio: A Relevant Marker of Gut Dysbiosis in Obese Patients?

(2020) Fabien Magne et al.   Nutrients

Effect of sulfate group on sulfated polysaccharides-induced improvement of metabolic syndrome and gut microbiota dysbiosis in high fat diet-fed mice

(2020) Shuang Wu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Polysaccharides isolated from Cordyceps Sinensis contribute to the progression of NASH by modifying the gut microbiota in mice fed a high-fat diet

(2020) Lei Chen et al.   PLoS One

Hypoglycemic mechanism of polysaccharide from Cyclocarya paliurus leaves in type 2 diabetic rats by gut microbiota and host metabolism alteration

(2020) Qiqiong Li et al.   Science China-Life Sciences

Gut Microbiota Profiles of Treated Metabolic Syndrome Patients and their Relationship with Metabolic Health

(2020) Montree Wutthi-in et al.   Scientific Reports

Polysaccharide fraction from greens of Raphanus sativus alleviates high fat diet-induced obesity

(2020) Moon Ho Do et al.   FOOD CHEMISTRY

Metabolic syndrome, metabolic comorbid conditions and risk of early-onset colorectal cancer

(2020) Hanyu Chen et al.   GUT

Effects of Nigella sativa seed polysaccharides on type 2 diabetic mice and gut microbiota

(2020) Jing Dong et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism

(2020) Jin He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypoglycemic and Hypolipidemic Mechanism of Tea Polysaccharides on Type 2 Diabetic Rats via Gut Microbiota and Metabolism Alteration

(2020) Haishan Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Intermittent Fasting Improves Cardiometabolic Risk Factors and Alters Gut Microbiota in Metabolic Syndrome Patients

(2020) Yi Guo et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Circadian rhythms and the gut microbiota: from the metabolic syndrome to cancer

(2020) Faraz Bishehsari et al.   Nature Reviews Endocrinology

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

Cyclocarya paliurus polysaccharides alleviate type 2 diabetic symptoms by modulating gut microbiota and short-chain fatty acids

(2020) Ye Yao et al.   PHYTOMEDICINE

Microbial Metabolites: Critical Regulators in NAFLD

(2020) Xin Dai et al.   Frontiers in Microbiology

Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy

(2020) Yu Gao et al.   Redox Biology

The Impact of Mushroom Polysaccharides on Gut Microbiota and Its Beneficial Effects to Host: A Review

(2020) Chaomin Yin et al.   CARBOHYDRATE POLYMERS

Sulfated polysaccharides from Undaria pinnatifida improved high fat diet-induced metabolic syndrome, gut microbiota dysbiosis and inflammation in BALB/c mice

(2020) Pingrui Jiang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The gut microbiota is associated with immune cell dynamics in humans

(2020) Jonas Schluter et al.   NATURE

COVID-19 alters thinking and management in metabolic diseases

(2020) Carel W. le Roux   Nature Reviews Endocrinology

Anti-Obesity Effect of Dictyophora indusiata Mushroom Polysaccharide (DIP) in High Fat Diet-Induced Obesity via Regulating Inflammatory Cascades and Intestinal Microbiome

(2020) Sadia Kanwal et al.   Frontiers in Endocrinology

Review of the relationships among polysaccharides, gut microbiota, and human health

(2020) Qianqian Song et al.   FOOD RESEARCH INTERNATIONAL

Gut microbial metabolites in obesity, NAFLD and T2DM

(2019) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

A new genomic blueprint of the human gut microbiota

(2019) Alexandre Almeida et al.   NATURE

Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial

(2019) Yi Wan et al.   GUT

The role of short-chain fatty acids in microbiota–gut–brain communication

(2019) Boushra Dalile et al.   Nature Reviews Gastroenterology & Hepatology

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

(2019) Gil Sharon et al.   CELL

Modified apple polysaccharide regulates microbial dysbiosis to suppress high-fat diet-induced obesity in C57BL/6J mice

(2019) Yuhua Li et al.   EUROPEAN JOURNAL OF NUTRITION

Mussel polysaccharide α-D-glucan (MP-A) protects against non-alcoholic fatty liver disease via maintaining the homeostasis of gut microbiota and regulating related gut-liver axis signaling pathways

(2019) Jixu Wu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer

(2019) Shinichi Yachida et al.   NATURE MEDICINE

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

(2019) Jordi Merino   BMJ-British Medical Journal

Statin use, hyperlipidemia, and risk of glioma

(2019) David J. Cote et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

MDG-1, an Ophiopogon polysaccharide, restrains process of non-alcoholic fatty liver disease via modulating the gut-liver axis

(2019) Xu Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Holothuria Leucospilota Polysaccharides Ameliorate Hyperlipidemia in High-Fat Diet-Induced Rats via Short-Chain Fatty Acids Production and Lipid Metabolism Regulation

(2019) Yiqiong Yuan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The gut microbiome and metabolic syndrome

(2019) Kruttika Dabke et al.   JOURNAL OF CLINICAL INVESTIGATION

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

(2019) Sunny H. Wong et al.   Nature Reviews Gastroenterology & Hepatology

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Alterations in Gut Microbiota by Statin Therapy and Possible Intermediate Effects on Hyperglycemia and Hyperlipidemia

(2019) Jiyeon Kim et al.   Frontiers in Microbiology

Changes of gut microbiota during silybin mediated treatment of high‐fat diet‐induced nonalcoholic fatty liver diseasein mouse

(2019) Xiuxia Li et al.   HEPATOLOGY RESEARCH

Artemisia sphaerocephala Krasch polysaccharide mediates lipid metabolism and metabolic endotoxaemia in associated with the modulation of gut microbiota in diet-induced obese mice

(2019) Junjun Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Intake of Ganoderma lucidum polysaccharides reverses the disturbed gut microbiota and metabolism in type 2 diabetic rats

(2019) Mingyi Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Hypoglycemic and hypolipidemic activities of Grifola frondosa polysaccharides and their relationships with the modulation of intestinal microflora in diabetic mice induced by high-fat diet and streptozotocin

(2019) Wei-Ling Guo et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program

(2019) David P. Labbé et al.   Nature Communications

Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids

(2019) Junki Miyamoto et al.   Nature Communications

Effect of mushroom polysaccharides from Pleurotus eryngii on obesity and gut microbiota in mice fed a high-fat diet

(2019) Daiki Nakahara et al.   EUROPEAN JOURNAL OF NUTRITION

High fat diet induces microbiota-dependent silencing of enteroendocrine cells

(2019) Lihua Ye et al.   eLife

Gut microbiota fermentation of marine polysaccharides and its effects on intestinal ecology: An overview

(2018) Qingsen Shang et al.   CARBOHYDRATE POLYMERS

Marine polysaccharides attenuate metabolic syndrome by fermentation products and altering gut microbiota: An overview

(2018) Xueliang Wang et al.   CARBOHYDRATE POLYMERS

Gut commensalParabacteroides goldsteiniiplays a predominant role in the anti-obesity effects of polysaccharides isolated fromHirsutella sinensis

(2018) Tsung-Ru Wu et al.   GUT

Pumpkin polysaccharide modifies the gut microbiota during alleviation of type 2 diabetes in rats

(2018) Guimei Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fuzhuan Brick Tea Polysaccharides Attenuate Metabolic Syndrome in High-Fat Diet Induced Mice in Association with Modulation in the Gut Microbiota

(2018) Guijie Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The gut–liver axis and the intersection with the microbiome

(2018) Anupriya Tripathi et al.   Nature Reviews Gastroenterology & Hepatology

Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague–Dawley rats

(2018) Victoria Svop Jensen et al.   Diabetology & Metabolic Syndrome

Polysaccharide from fermented Momordica charantia L. with Lactobacillus plantarum NCU116 ameliorates type 2 diabetes in rats

(2018) He Gao et al.   CARBOHYDRATE POLYMERS

Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease

(2018) Huikuan Chu et al.   GUT

Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain-gut axis alterations

(2018) Marcel van de Wouw et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sulfated Polysaccharide from Sea Cucumber and its Depolymerized Derivative Prevent Obesity in Association with Modification of Gut Microbiota in High-Fat Diet-Fed Mice

(2018) Zhenjun Zhu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A fucoidan from sea cucumber Pearsonothuria graeffei with well-repeated structure alleviates gut microbiota dysbiosis and metabolic syndromes in HFD-fed mice

(2018) Shan Li et al.   Food & Function

Polysaccharides from Laminaria japonica alleviated metabolic syndrome in BALB/c mice by normalizing the gut microbiota

(2018) Mengmeng Duan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Polygonatum odoratum Polysaccharides Modulate Gut Microbiota and Mitigate Experimentally Induced Obesity in Rats

(2018) Yan Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SIRT3 Deficiency Promotes High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Correlation with Impaired Intestinal Permeability through Gut Microbial Dysbiosis

(2018) Mengting Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The gut microbiota at the intersection of diet and human health

(2018) Christopher L. Gentile et al.   SCIENCE

Fucosylated chondroitin sulfate from Isostichopus badionotus alleviates metabolic syndromes and gut microbiota dysbiosis induced by high-fat and high-fructose diet

(2018) Shan Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Sirtuin 3 acts as a negative regulator of autophagy dictating hepatocyte susceptibility to lipotoxicity

(2017) Songtao Li et al.   HEPATOLOGY

Dietary Uncoupling of Gut Microbiota and Energy Harvesting from Obesity and Glucose Tolerance in Mice

(2017) Matthew J. Dalby et al.   Cell Reports

Balancing Herbal Medicine and Functional Food for Prevention and Treatment of Cardiometabolic Diseases through Modulating Gut Microbiota

(2017) Ming Lyu et al.   Frontiers in Microbiology

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Roles of the gut in the metabolic syndrome: an overview

(2016) L. Fändriks   JOURNAL OF INTERNAL MEDICINE

An obligatory role for neurotensin in high-fat-diet-induced obesity

(2016) Jing Li et al.   NATURE

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

(2016) Semir Beyaz et al.   NATURE

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

The role of the gut microbiota in NAFLD

(2016) Christopher Leung et al.   Nature Reviews Gastroenterology & Hepatology

High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine

(2016) Julie Tomas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirtuins and nonalcoholic fatty liver disease

(2016) Fatiha Nassir et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Altered Fecal Microbiota Correlates with Liver Biochemistry in Nonobese Patients with Non-alcoholic Fatty Liver Disease

(2016) Baohong Wang et al.   Scientific Reports

Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

(2015) Gijs den Besten et al.   DIABETES

Systematic review on intervention with prebiotics/probiotics in patients with obesity-related nonalcoholic fatty liver disease

(2015) Giovanni Tarantino et al.   Future Microbiology

The gut microbiota and host health: a new clinical frontier

(2015) Julian R Marchesi et al.   GUT

Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children

(2015) Chenhong Zhang et al.   EBioMedicine

Starving our Microbial Self: The Deleterious Consequences of a Diet Deficient in Microbiota-Accessible Carbohydrates

(2014) Erica D. Sonnenburg et al.   Cell Metabolism

Microbiota and diabetes: an evolving relationship

(2014) Herbert Tilg et al.   GUT

Weight-loss surgery: A gut-wrenching question

(2014) Virginia Hughes   NATURE

Circulating Levels of Sirtuin 4, a Potential Marker of Oxidative Metabolism, Related to Coronary Artery Disease in Obese Patients Suffering from NAFLD, with Normal or Slightly Increased Liver Enzymes

(2014) Giovanni Tarantino et al.   Oxidative Medicine and Cellular Longevity

SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation

(2013) Gaëlle Laurent et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

(2013) James Soh et al.   NATURE MEDICINE

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

(2012) Tiphaine Le Roy et al.   GUT

The interpersonal and intrapersonal diversity of human-associated microbiota in key body sites

(2012) Luke K. Ursell et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism

(2010) Sylvie Rabot et al.   FASEB JOURNAL

SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells

(2010) Nargis Nasrin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global burden of obesity in 2005 and projections to 2030

(2008) T Kelly et al.   INTERNATIONAL JOURNAL OF OBESITY