Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy
出版年份 2022 全文链接
标题
Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy
作者
关键词
-
出版物
Journal of Hematology & Oncology
Volume 15, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-03-25
DOI
10.1186/s13045-022-01252-0
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting hypoxic tumor microenvironment in pancreatic cancer
- (2021) Jinxin Tao et al. Journal of Hematology & Oncology
- Mechanical Stiffness Controls Dendritic Cell Metabolism and Function
- (2021) Mainak Chakraborty et al. Cell Reports
- Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity
- (2021) Anantha K. Kanugula et al. ANGIOGENESIS
- Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
- (2021) Tengfei Huang et al. Autophagy
- Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours
- (2021) Yordanos F.I. Setargew et al. Cancers
- LOXL2 Inhibitors and Breast Cancer Progression
- (2021) Sandra Ferreira et al. Antioxidants
- SEPHS1 promotes SMAD2/3/4 expression and hepatocellular carcinoma cells invasion
- (2021) Shu Yang et al. Experimental Hematology & Oncology
- MiRNA-mediated EMT and CSCs in cancer chemoresistance
- (2021) Bing Dong et al. Experimental Hematology & Oncology
- TRPV4 antagonists: a patent review (2015–2020)
- (2021) Brian G. Lawhorn et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer
- (2021) Allison P. Drain et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Role of IGF/IGF-IR-Signaling and Extracellular Matrix Effectors in Bone Sarcoma Pathogenesis
- (2021) George N. Tzanakakis et al. Cancers
- FK506 binding protein 10: a key actor of collagen crosslinking in clear cell renal cell carcinoma
- (2021) Yubai Zhang et al. Aging-US
- Targeting Na + /K + ‐ATPase by berbamine and ouabain synergizes with sorafenib to inhibit hepatocellular carcinoma
- (2021) Songpeng Yang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Mechanosensitive turnover of phosphoribosyl pyrophosphate synthetases regulates nucleotide metabolism
- (2021) Jingyi Li et al. CELL DEATH AND DIFFERENTIATION
- The relationship between expression of PD-L1 and HIF-1α in glioma cells under hypoxia
- (2021) Xing-chen Ding et al. Journal of Hematology & Oncology
- Targeting the tumor microenvironment in B-cell lymphoma: challenges and opportunities
- (2021) Yingyue Liu et al. Journal of Hematology & Oncology
- Targeting Akt in cancer for precision therapy
- (2021) Hui Hua et al. Journal of Hematology & Oncology
- Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein–Protein Interaction with α-Parvin
- (2021) Javier Garcia-Marin et al. ACS Medicinal Chemistry Letters
- Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance
- (2021) Elina A. Pietilä et al. Nature Communications
- Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing
- (2021) Hamza Atcha et al. Nature Communications
- Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment
- (2021) Alba Nicolas-Boluda et al. eLife
- YAP and TAZ are transcriptional co-activators of AP-1 proteins and STAT3 during breast cellular transformation
- (2021) Lizhi He et al. eLife
- Crosstalk Between CD11b and Piezo1 Mediates Macrophage Responses to Mechanical Cues
- (2021) Hamza Atcha et al. Frontiers in Immunology
- Piezo1 channels restrain regulatory T cells but are dispensable for effector CD4+ T cell responses
- (2021) Amit Jairaman et al. Science Advances
- Pancreatic Ductal Adenocarcinoma: Relating Biomechanics and Prognosis
- (2021) Benjamin M. MacCurtain et al. Journal of Clinical Medicine
- The Biological and Biomechanical Role of Transglutaminase-2 in the Tumour Microenvironment
- (2021) Robert Tempest et al. Cancers
- The Extracellular Matrix in Pancreatic Cancer: Description of a Complex Network and Promising Therapeutic Options
- (2021) Benedetta Ferrara et al. Cancers
- TRPV Protein Family—From Mechanosensing to Cancer Invasion
- (2021) Tytti Kärki et al. Biomolecules
- Endothelial TRPV4– eNOS coupling as a vital therapy target for treatment of hypertension
- (2021) Aiqin Mao et al. BRITISH JOURNAL OF PHARMACOLOGY
- Molecular Mechanisms and Cellular Contribution from Lung Fibrosis to Lung Cancer Development
- (2021) Anna Valeria Samarelli et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Integrins regulate stemness in solid tumor: an emerging therapeutic target
- (2021) Jiangling Xiong et al. Journal of Hematology & Oncology
- Matrix stiffness drives stromal autophagy and promotes formation of a protumorigenic niche
- (2021) Anna Hupfer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Piezo1 ion channels inherently function as independent mechanotransducers
- (2021) Amanda H Lewis et al. eLife
- Mechanical Aspects of Angiogenesis
- (2021) Maibritt Kretschmer et al. Cancers
- Channeling the Force: Piezo1 Mechanotransduction in Cancer Metastasis
- (2021) Jenna A. Dombroski et al. Cells
- Dendritic Cell Migration Is Tuned by Mechanical Stiffness of the Confining Space
- (2021) Yongjun Choi et al. Cells
- Senescent mesenchymal stem cells remodel extracellular matrix driving breast cancer cells to a more-invasive phenotype
- (2020) Deepraj Ghosh et al. JOURNAL OF CELL SCIENCE
- Stiffer Matrix Accelerates Migration of Hepatocellular Carcinoma Cells through Enhanced Aerobic Glycolysis Via the MAPK-YAP Signaling
- (2020) Qiu-Ping Liu et al. Cancers
- Fibrosis and cancer: A strained relationship
- (2020) Bram Piersma et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Collagen biology making inroads into prognosis and treatment of cancer progression and metastasis
- (2020) Ana C. Martins Cavaco et al. CANCER AND METASTASIS REVIEWS
- Next-generation immuno-oncology agents: current momentum shifts in cancer immunotherapy
- (2020) Chongxian Pan et al. Journal of Hematology & Oncology
- Emerging therapeutic agents for advanced non-small cell lung cancer
- (2020) Ruqin Chen et al. Journal of Hematology & Oncology
- Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy
- (2020) Xin Li et al. Journal of Hematology & Oncology
- Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling
- (2020) Yoshito Yamashiro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small molecule inhibitor of HSP47 prevents pro-fibrotic mechanisms of fibroblasts in vitro
- (2020) Takuto Miyamura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
- (2020) Ying Shen et al. CANCER CELL
- Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex
- (2020) Laurent Fattet et al. DEVELOPMENTAL CELL
- Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma
- (2020) Xiangxiang Zhou et al. Journal of Hematology & Oncology
- Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy
- (2020) Hui Hua et al. Journal of Hematology & Oncology
- Matrix stiffness-sensitive long noncoding RNA NEAT1 seeded paraspeckles in cancer cells
- (2020) Vanja Todorovski et al. MOLECULAR BIOLOGY OF THE CELL
- Mechanosensitive Piezo Channels in Cancer: Focus on altered Calcium Signaling in Cancer Cells and in Tumor Progression
- (2020) Dario De Felice et al. Cancers
- Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity
- (2020) Pablo Doñate‐Macian et al. BRITISH JOURNAL OF PHARMACOLOGY
- Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
- (2020) Jason J. Northey et al. JOURNAL OF CLINICAL INVESTIGATION
- Dendritic cell biology and its role in tumor immunotherapy
- (2020) Yingying Wang et al. Journal of Hematology & Oncology
- Collagen Density Modulates the Immunosuppressive Functions of Macrophages
- (2020) Anne Mette H. Larsen et al. JOURNAL OF IMMUNOLOGY
- YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation
- (2020) Kana Hasegawa et al. JOURNAL OF PATHOLOGY
- Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion
- (2020) David H. Peng et al. Nature Communications
- Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents
- (2020) Min Deng et al. Science Advances
- Matrix Stiffness-Upregulated MicroRNA-17-5p Attenuates the Intervention Effects of Metformin on HCC Invasion and Metastasis by Targeting the PTEN/PI3K/Akt Pathway
- (2020) Xiangyu Gao et al. Frontiers in Oncology
- Abnormally activated OPN/integrin αVβ3/FAK signalling is responsible for EGFR-TKI resistance in EGFR mutant non-small-cell lung cancer
- (2020) Yulong Fu et al. Journal of Hematology & Oncology
- Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression
- (2020) Ori Maller et al. NATURE MATERIALS
- Tumor Microenvironment Uses a Reversible Reprogramming of Mesenchymal Stromal Cells to Mediate Pro-tumorigenic Effects
- (2020) Armel H. Nwabo Kamdje et al. Frontiers in Cell and Developmental Biology
- Clinical Pharmacokinetics, Safety, and Tolerability of a Novel, First-in-Class TRPV4 Ion Channel Inhibitor, GSK2798745, in Healthy and Heart Failure Subjects
- (2019) Navin Goyal et al. American Journal of Cardiovascular Drugs
- Collagen density regulates the activity of tumor-infiltrating T cells
- (2019) Dorota E. Kuczek et al. Journal for ImmunoTherapy of Cancer
- UBTD1 is a mechano‐regulator controlling cancer aggressiveness
- (2019) Stéphanie Torrino et al. EMBO REPORTS
- Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation
- (2019) Jason E. Long et al. CELL DEATH AND DIFFERENTIATION
- The extracellular matrix in tumor progression and metastasis
- (2019) Johannes A. Eble et al. CLINICAL & EXPERIMENTAL METASTASIS
- RASSF1A controls tissue stiffness and cancer stem‐like cells in lung adenocarcinoma
- (2019) Daniela Pankova et al. EMBO JOURNAL
- Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure–Activity Relationships
- (2019) Leo Leung et al. JOURNAL OF MEDICINAL CHEMISTRY
- Revisiting the hallmarks of cancer: The role of hyaluronan
- (2019) Ilaria Caon et al. SEMINARS IN CANCER BIOLOGY
- Lysyl oxidases: from enzyme activity to extracellular matrix cross-links
- (2019) Sylvain D. Vallet et al. Essays in Biochemistry
- Fibronectin in malignancy: Cancer-specific alterations, protumoral effects, and therapeutic implications
- (2019) Jonathan W Rick et al. SEMINARS IN ONCOLOGY
- Matrix stiffness modulates ILK-mediated YAP activation to control the drug resistance of breast cancer cells
- (2019) Xiang Qin et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A hierarchical network of hypoxia-inducible factor and SMAD proteins governs procollagen lysyl hydroxylase 2 induction by hypoxia and transforming growth factor β1
- (2019) Tamara Rosell-García et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Higher matrix stiffness as an independent initiator triggers epithelial-mesenchymal transition and facilitates HCC metastasis
- (2019) Yinying Dong et al. Journal of Hematology & Oncology
- Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3
- (2019) Alison D. Findlay et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mechanotransduction in Liver Diseases
- (2019) Ningling Kang SEMINARS IN LIVER DISEASE
- Controlling Immunity and Inflammation through Integrin-Dependent Regulation of TGF-β
- (2019) Martijn Nolte et al. TRENDS IN CELL BIOLOGY
- The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1
- (2018) Helena J. Janse van Rensburg et al. CANCER RESEARCH
- Tumor elastography and its association with collagen and the tumor microenvironment.
- (2018) Johannes Riegler et al. CLINICAL CANCER RESEARCH
- Novel non-canonical regulation of soluble VEGF/VEGFR2 signaling by mechanosensitive ion channel TRPV4
- (2018) Anantha K. Kanugula et al. FASEB JOURNAL
- Simtuzumab Is Ineffective for Patients with Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis
- (2018) Stephen A. Harrison et al. GASTROENTEROLOGY
- P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts
- (2018) Changwei Dou et al. GASTROENTEROLOGY
- Periostin promotes liver fibrogenesis by activating lysyl oxidase in hepatic stellate cells
- (2018) Pradeep Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The endoplasmic reticulum-resident collagen chaperone Hsp47 interacts with and promotes the secretion of decorin, fibromodulin and lumican
- (2018) Yoshihiro Ishikawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Digesting a Path Forward: The Utility of Collagenase Tumor Treatment for Improved Drug Delivery
- (2018) Aaron Dolor et al. MOLECULAR PHARMACEUTICS
- Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes
- (2018) Aida Olivan-Viguera et al. PLoS One
- An overview of mammographic density and its association with breast cancer
- (2018) Shayan Shaghayeq Nazari et al. Breast Cancer
- YAP-Induced PD-L1 Expression Drives Immune Evasion in BRAFi-Resistant Melanoma
- (2018) Min Hwan Kim et al. Cancer Immunology Research
- Cancer cells’ ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential
- (2018) Lena Wullkopf et al. MOLECULAR BIOLOGY OF THE CELL
- Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem
- (2018) Xuexiang Han et al. Nature Communications
- Lysyl hydroxylases are transcription targets for GATA3 driving lung cancer cell metastasis
- (2018) Wei Liu et al. Scientific Reports
- Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin
- (2018) M. Hunter Joyce et al. Frontiers in Oncology
- Rho–ROCK signaling regulates tumor-microenvironment interactions
- (2018) Mohammad Zahied Johan et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- TRPV4 regulates matrix stiffness and TGFβ1-induced epithelial-mesenchymal transition
- (2018) Shweta Sharma et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis
- (2018) Heidi Schilter et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression
- (2018) Xin Chen et al. NEURON
- A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis
- (2017) Shinya Ito et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin
- (2017) Begum Erdogan et al. JOURNAL OF CELL BIOLOGY
- Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1
- (2017) Sunbin Ling et al. Journal of Hematology & Oncology
- Mammary epithelium-specific inactivation of V-ATPase reduces stiffness of extracellular matrix and enhances metastasis of breast cancer
- (2017) Gajendra K. Katara et al. Molecular Oncology
- Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells
- (2017) A A Peters et al. ONCOGENE
- A Phase II, Randomized, Double‐Blind, Placebo‐Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second‐Line Treatment of MetastaticKRASMutant Colorectal Adenocarcinoma
- (2017) J. Randolph Hecht et al. ONCOLOGIST
- A Phase II Randomized, Double‐Blind, Placebo‐Controlled Study of Simtuzumab or Placebo in Combination with Gemcitabine for the First‐Line Treatment of Pancreatic Adenocarcinoma
- (2017) Al B. Benson et al. ONCOLOGIST
- Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
- (2017) Claire Vennin et al. Science Translational Medicine
- Laminins and cancer stem cells: Partners in crime?
- (2017) Yan Qin et al. SEMINARS IN CANCER BIOLOGY
- Extracellular matrix stiffness and cell contractility control RNA localization to promote cell migration
- (2017) Tianhong Wang et al. Nature Communications
- Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer
- (2017) Joan Chang et al. Oncotarget
- DDR2 controls the epithelial-mesenchymal-transition-related gene expression via c-Myb acetylation upon matrix stiffening
- (2017) Daehwan Kim et al. Scientific Reports
- Tumor Stiffening, a Key Determinant of Tumor Progression, is Reversed by Nanomaterial-Induced Photothermal Therapy
- (2017) Iris Marangon et al. Theranostics
- Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells
- (2017) A J Rice et al. Oncogenesis
- TRPV4 plays a role in breast cancer cell migration via Ca2+-dependent activation of AKT and downregulation of E-cadherin cell cortex protein
- (2017) W H Lee et al. Oncogenesis
- Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth
- (2017) Anisha M. Hammer et al. NEOPLASIA
- Substrate stiffness influences phenotype and function of human antigen-presenting dendritic cells
- (2017) Svenja F. B. Mennens et al. Scientific Reports
- The SPARC protein: an overview of its role in lung cancer and pulmonary fibrosis and its potential role in chronic airways disease
- (2016) Sharon L I Wong et al. BRITISH JOURNAL OF PHARMACOLOGY
- Hypoxic stellate cells of pancreatic cancer stroma regulate extracellular matrix fiber organization and cancer cell motility
- (2016) Masafumi Sada et al. CANCER LETTERS
- Antagonizing Integrin 3 Increases Immunosuppression in Cancer
- (2016) X. Su et al. CANCER RESEARCH
- ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth
- (2016) Nicola Rath et al. EMBO Molecular Medicine
- Lysyl Hydroxylase 2 Is Secreted by Tumor Cells and Can Modify Collagen in the Extracellular Space
- (2016) Yulong Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TGF-β: the master regulator of fibrosis
- (2016) Xiao-ming Meng et al. Nature Reviews Nephrology
- ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis
- (2016) D H Peng et al. ONCOGENE
- ROCK2/ras Ha co-operation induces malignant conversion via p53 loss, elevated NF-κB and tenascin C-associated rigidity, but p21 inhibits ROCK2/NF-κB-mediated progression
- (2016) S F Masre et al. ONCOGENE
- Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI)
- (2016) I García-Palmero et al. ONCOGENE
- Disentangling mechanisms involved in collagen pyridinoline cross-linking: The immunophilin FKBP65 is critical for dimerization of lysyl hydroxylase 2
- (2016) Rutger A. F. Gjaltema et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- De novo design based pharmacophore query generation and virtual screening for the discovery of Hsp-47 inhibitors
- (2015) Atul Katarkar et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis
- (2015) Ayumi Iwasaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
- (2015) Yulong Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors
- (2015) Chun-Han Lin et al. MOLECULAR BIOLOGY OF THE CELL
- Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma
- (2015) D. Pankova et al. MOLECULAR CANCER RESEARCH
- Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway
- (2015) Spencer C. Wei et al. NATURE CELL BIOLOGY
- Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumors
- (2015) Francois Bordeleau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression
- (2015) A Nukuda et al. Oncogenesis
- Dense Collagen-I Matrices Enhance Pro-Tumorigenic Estrogen-Prolactin Crosstalk in MCF-7 and T47D Breast Cancer Cells
- (2015) Craig E. Barcus et al. PLoS One
- Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening
- (2014) Thuy V. Nguyen et al. BIOMATERIALS
- Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer
- (2014) M T Huggett et al. BRITISH JOURNAL OF CANCER
- Force Engages Vinculin and Promotes Tumor Progression by Enhancing PI3K Activation of Phosphatidylinositol (3,4,5)-Triphosphate
- (2014) Matthew G. Rubashkin et al. CANCER RESEARCH
- Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial
- (2014) Roger Stupp et al. LANCET ONCOLOGY
- Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium
- (2014) Ovijit Chaudhuri et al. NATURE MATERIALS
- Remodelling the extracellular matrix in development and disease
- (2014) Caroline Bonnans et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanotransduction Pathways Promoting Tumor Progression Are Activated in Invasive Human Squamous Cell Carcinoma
- (2013) S. Jan Ibbetson et al. AMERICAN JOURNAL OF PATHOLOGY
- Stiff Collagen Matrices Increase Tumorigenic Prolactin Signaling in Breast Cancer Cells
- (2013) Craig E. Barcus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hedgehog-Gli Activators Direct Osteo-chondrogenic Function of Bone Morphogenetic Protein toward Osteogenesis in the Perichondrium
- (2013) Hironori Hojo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by InducingP4HA1, P4HA2,andPLOD2Expression in Fibroblasts
- (2013) Daniele M. Gilkes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
- (2013) Yong Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- Soft matrix is a natural stimulator for cellular invasiveness
- (2013) Zhizhan Gu et al. MOLECULAR BIOLOGY OF THE CELL
- Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway
- (2012) Li-Ching Chen et al. BREAST CANCER RESEARCH AND TREATMENT
- Treatment of pancreatic fibrosis with siRNA against a collagen-specific chaperone in vitamin A-coupled liposomes
- (2012) Hirotoshi Ishiwatari et al. GUT
- Randomized phase II study of three doses of the integrin inhibitor cilengitide versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer
- (2012) Christian Manegold et al. INVESTIGATIONAL NEW DRUGS
- Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
- (2012) A-M Baker et al. ONCOGENE
- Pirfenidone inhibits TGF-β1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells
- (2012) Keiko Hisatomi et al. BMC Pulmonary Medicine
- The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4
- (2011) Chilman Bae et al. BIOCHEMISTRY
- Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth
- (2011) Michael S. Samuel et al. CANCER CELL
- Anti-cancer role of SPARC, an inhibitor of adipogenesis
- (2011) Ganji Purna Chandra Nagaraju et al. CANCER TREATMENT REVIEWS
- Matrix metalloproteinases in tumorigenesis: an evolving paradigm
- (2011) Hui Hua et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor
- (2011) Su-Lin Lee et al. JOURNAL OF MEDICINAL CHEMISTRY
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration
- (2011) J. Huynh et al. Science Translational Medicine
- Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells
- (2010) Jörg Schrader et al. HEPATOLOGY
- Increased extracellular pressure provides a novel adjuvant stimulus for enhancement of conventional dendritic cell maturation strategies
- (2009) David H. Craig et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
- (2009) Kandice R. Levental et al. CELL
- Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage
- (2009) P P Provenzano et al. ONCOGENE
- Resolution of liver cirrhosis using vitamin A–coupled liposomes to deliver siRNA against a collagen-specific chaperone
- (2008) Yasushi Sato et al. NATURE BIOTECHNOLOGY
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