Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis

Matricellular Protein Periostin Contributes to Hepatic Inflammation and Fibrosis

(2015) Yangmei Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of fibronectin deposition improves experimental liver fibrosis

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Nanoscale characterization of the biomechanical properties of collagen fibrils in the sclera

(2014) M. Papi et al.   APPLIED PHYSICS LETTERS

Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening

(2014) Ruogang Zhao et al.   BIOMATERIALS

Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury

(2013) Maryna Perepelyuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Evolving therapies for liver fibrosis

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Underlying potential: cellular and molecular determinants of adult liver repair

(2013) Anna Mae Diehl et al.   JOURNAL OF CLINICAL INVESTIGATION

Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics

(2013) Akiko Mammoto et al.   Nature Communications

Fibronectin is essential for survival but is dispensable for proliferation of hepatocytes in acute liver injury in mice

(2012) Kei Moriya et al.   HEPATOLOGY

Biological Significance of Local TGF-β Activation in Liver Diseases

(2012) Hiromitsu Hayashi et al.   Frontiers in Physiology

Liver fibrogenic cells

(2011) Stuart J. Forbes et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Conversion of Mechanical Force into TGF-β-Mediated Biochemical Signals

(2011) Toru Maeda et al.   CURRENT BIOLOGY

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling

(2011) Tetyana G. Voloshenyuk et al.   CYTOKINE

A Fibronectin-Independent Mechanism of Collagen Fibrillogenesis in Adult Liver Remodeling

(2011) Kei Moriya et al.   GASTROENTEROLOGY

Fibronectin Extra Domain-A Promotes Hepatic Stellate Cell Motility but Not Differentiation Into Myofibroblasts

(2011) Abby L. Olsen et al.   GASTROENTEROLOGY

Fibronectin Protects from Excessive Liver Fibrosis by Modulating the Availability of and Responsiveness of Stellate Cells to Active TGF-β

(2011) Nina Kawelke et al.   PLoS One

Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing

(2010) Coert Margadant et al.   EMBO REPORTS

Interaction between Periostin and BMP-1 Promotes Proteolytic Activation of Lysyl Oxidase

(2010) Takumi Maruhashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation

(2010) Harikiran Nistala et al.   JOURNAL OF CELL BIOLOGY

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

(2010) Vivian Barry-Hamilton et al.   NATURE MEDICINE

Evolving challenges in hepatic fibrosis

(2010) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology

Mutations in Fibrillin-1 Cause Congenital Scleroderma: Stiff Skin Syndrome

(2010) B. L. Loeys et al.   Science Translational Medicine

Integrin-Mediated Transforming Growth Factor-β Activation, a Potential Therapeutic Target in Fibrogenic Disorders

(2009) Stephen L. Nishimura   AMERICAN JOURNAL OF PATHOLOGY

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Extracellular microfibrils: contextual platforms for TGFβ and BMP signaling

(2009) Francesco Ramirez et al.   CURRENT OPINION IN CELL BIOLOGY

The regulation of TGF  signal transduction

(2009) A. Moustakas et al.   DEVELOPMENT

Fibronectin Binds and Enhances the Activity of Bone Morphogenetic Protein 1

(2009) Guorui Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transforming growth factor β as a therapeutic target in systemic sclerosis

(2009) John Varga et al.   Nature Reviews Rheumatology

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Liver fibrosis

(2008) Karen Wallace et al.   BIOCHEMICAL JOURNAL

Fibrin architecture in clots: A quantitative polarized light microscopy analysis☆

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Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET

Perturbation of transforming growth factor (TGF)-ss1 association with latent TGF-  binding protein yields inflammation and tumors

(2008) K. Yoshinaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in FN1 cause glomerulopathy with fibronectin deposits

(2008) F. Castelletti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of the latent transforming growth factor-β binding protein-1 gene causes alteration in facial structure and influences TGF-β bioavailability

(2007) Falko Drews et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH