Matrix metalloproteinases in tumorigenesis: an evolving paradigm

Matrix Metalloproteinase-9 and Cell Division in Neuroblastoma Cells and Bone Marrow Macrophages

(2010) M. Gloria Sans-Fons et al.   AMERICAN JOURNAL OF PATHOLOGY

Stromelysin-1 (MMP-3) is a target and a regulator of Wnt1-induced epithelial-mesenchymal transition (EMT)

(2010) Laurence Blavier et al.   CANCER BIOLOGY & THERAPY

Matrix Metalloproteinase (MMP)-13 Regulates Mammary Tumor–Induced Osteolysis by Activating MMP9 and Transforming Growth Factor-β Signaling at the Tumor-Bone Interface

(2010) Kalyan C. Nannuru et al.   CANCER RESEARCH

Shedding of RANKL by Tumor-Associated MT1-MMP Activates Src-Dependent Prostate Cancer Cell Migration

(2010) A. L. Sabbota et al.   CANCER RESEARCH

Matrix Metalloproteinase-14 (MT1-MMP)-Mediated Endoglin Shedding Inhibits Tumor Angiogenesis

(2010) L. J. A. C. Hawinkels et al.   CANCER RESEARCH

Membrane Type 1-Matrix Metalloproteinase Cleaves Off the NH2-Terminal Portion of Heparin-Binding Epidermal Growth Factor and Converts It into a Heparin-Independent Growth Factor

(2010) N. Koshikawa et al.   CANCER RESEARCH

Matrix Metalloproteinase-9 Regulates Tumor Cell Invasion through Cleavage of Protease Nexin-1

(2010) D. Xu et al.   CANCER RESEARCH

TIMP-1 interaction with αvβ3 integrin confers resistance to human osteosarcoma cell line MG-63 against TNF-α-induced apoptosis

(2010) Ioanna Tsagaraki et al.   CELL AND TISSUE RESEARCH

Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress

(2010) Eun-Mee Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Wnt/Planar Cell Polarity Protein-tyrosine Kinase-7 (PTK7) Is a Highly Efficient Proteolytic Target of Membrane Type-1 Matrix Metalloproteinase

(2010) Vladislav S. Golubkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src

(2010) Patricia A. Eisenach et al.   JOURNAL OF CELL SCIENCE

TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells

(2010) Seo-Jin Lee et al.   LABORATORY INVESTIGATION

Matrix Metalloproteinase 1: Role in Sarcoma Biology

(2010) Muhammad Umar Jawad et al.   PLoS One

Matrix Metalloproteinase 2 Inhibition: Combined Quantum Mechanics and Molecular Mechanics Studies of the Inhibition Mechanism of (4-Phenoxyphenylsulfonyl)methylthiirane and Its Oxirane Analogue

(2009) Peng Tao et al.   BIOCHEMISTRY

The Serine Protease Inhibitor Protease Nexin-1 Controls Mammary Cancer Metastasis through LRP-1-Mediated MMP-9 Expression

(2009) B. Fayard et al.   CANCER RESEARCH

Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

(2009) Laetitia Devy et al.   CANCER RESEARCH

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia

(2009) R. Poincloux et al.   JOURNAL OF CELL SCIENCE

Tissue inhibitor of metalloproteinases-1-induced scattered liver metastasis is mediated by host-derived urokinase-type plasminogen activator

(2009) Florian Schrötzlmair et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Role of MMP7 and Its Cross-Talk with the FAS/FASL System during the Acquisition of Chemoresistance to Oxaliplatin

(2009) Vanessa Almendro et al.   PLoS One

Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1

(2009) I. Ota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Degradation of soluble VEGF receptor-1 by MMP-7 allows VEGF access to endothelial cells

(2008) T.-K. Ito et al.   BLOOD

TIMP-1 overexpression promotes tumorigenesis of MDA-MB-231 breast cancer cells and alters expression of a subset of cancer promoting genes in vivo distinct from those observed in vitro

(2008) Rebecca L. H. Bigelow et al.   BREAST CANCER RESEARCH AND TREATMENT

MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer

(2008) Anjum Sohail et al.   CANCER AND METASTASIS REVIEWS

Tube Travel: The Role of Proteases in Individual and Collective Cancer Cell Invasion

(2008) P. Friedl et al.   CANCER RESEARCH

Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion

(2008) A. Gutierrez-Fernandez et al.   CANCER RESEARCH

Effect of Ablation or Inhibition of Stromal Matrix Metalloproteinase-9 on Lung Metastasis in a Breast Cancer Model Is Dependent on Genetic Background

(2008) M. D. Martin et al.   CANCER RESEARCH

Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression

(2008) C. Blazquez et al.   CANCER RESEARCH

Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomas

(2008) Sandrine Rorive et al.   GLIA

Selective Modulation of Matrix Metalloproteinase 9 (MMP-9) Functions via Exosite Inhibition

(2008) Janelle L. Lauer-Fields et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carbamoylphosphonate Matrix Metalloproteinase Inhibitors 6:cis-2-Aminocyclohexylcarbamoylphosphonic Acid, A Novel Orally Active Antimetastatic Matrix Metalloproteinase-2 Selective InhibitorSynthesis and Pharmacodynamic and Pharmacokinetic Analysis

(2008) Amnon Hoffman et al.   JOURNAL OF MEDICINAL CHEMISTRY

TIMP-2 disrupts FGF-2-induced downstream signaling pathways

(2008) Dong-Wan Seo et al.   MICROVASCULAR RESEARCH

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY