标题
RIP1 post-translational modifications
作者
关键词
-
出版物
BIOCHEMICAL JOURNAL
Volume 479, Issue 9, Pages 929-951
出版商
Portland Press Ltd.
发表日期
2022-05-06
DOI
10.1042/bcj20210725
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The regulation of necroptosis by post-translational modifications
- (2021) Yanxiang Meng et al. CELL DEATH AND DIFFERENTIATION
- Cell death pathways: intricate connections and disease implications
- (2021) Matthias Kist et al. EMBO JOURNAL
- ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1
- (2021) Hayley I. Muendlein et al. Nature Communications
- MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL
- (2021) Osamu Nakabayashi et al. Communications Biology
- Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
- (2021) Justin Taft et al. CELL
- Linear Ubiquitination of RIPK1 on Lys612 Regulates Systemic Inflammation via Preventing Cell Death
- (2021) Hailin Tu et al. JOURNAL OF IMMUNOLOGY
- RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling
- (2021) Kaiwen W. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice
- (2021) Hannah Schünke et al. Nature Communications
- RIPK1 dephosphorylation and kinase activation by PPP1R3G/PP1γ promote apoptosis and necroptosis
- (2021) Jingchun Du et al. Nature Communications
- Caspases in Cell Death, Inflammation, and Gasdermin-Induced Pyroptosis
- (2020) Sannula Kesavardhana et al. Annual Review of Immunology
- OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis
- (2020) Lien Verboom et al. Cell Reports
- OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer
- (2020) Rune Busk Damgaard et al. CELL DEATH AND DIFFERENTIATION
- Toll-like receptor 4: A promising crossroads in the diagnosis and treatment of several pathologies
- (2020) Miguel M. Garcia et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Non-catalytic ubiquitin binding by A20 prevents psoriatic arthritis–like disease and inflammation
- (2020) Bahram Razani et al. NATURE IMMUNOLOGY
- Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation
- (2020) Lucie Laurien et al. Nature Communications
- The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
- (2020) Wenxian Wu et al. Cell Reports
- The Balance of TNF Mediated Pathways Regulates Inflammatory Cell Death Signaling in Healthy and Diseased Tissues
- (2020) Joshua D. Webster et al. Frontiers in Cell and Developmental Biology
- Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target
- (2020) Lauren Mifflin et al. NATURE REVIEWS DRUG DISCOVERY
- Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death
- (2020) Matthias Kist et al. CELL DEATH AND DIFFERENTIATION
- 25 years of research put RIPK1 in the clinic
- (2020) Lin Liu et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- RIPK1 ubiquitination: Evidence, correlations and the undefined
- (2020) Daniel S. Simpson et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners
- (2020) Xingyan Li et al. Nature Communications
- RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development
- (2019) Xuhua Zhang et al. Cell Death & Disease
- OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell death
- (2019) Rune Busk Damgaard et al. EMBO Molecular Medicine
- RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases
- (2019) Snahel Patel et al. CELL DEATH AND DIFFERENTIATION
- Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
- (2019) Yves Dondelinger et al. Nature Communications
- Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation
- (2019) Jieqiong Zhang et al. Cell Reports
- Caspases in Cell Death, Inflammation, and Disease
- (2019) Nina Van Opdenbosch et al. IMMUNITY
- The E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD
- (2019) Atsushi Uematsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Primary immunodeficiency with chronic enteropathy and developmental delay in a boy arising from a novel homozygous RIPK1 variant
- (2019) Yuri Uchiyama et al. JOURNAL OF HUMAN GENETICS
- The AMPK–Parkin axis negatively regulates necroptosis and tumorigenesis by inhibiting the necrosome
- (2019) Seung Baek Lee et al. NATURE CELL BIOLOGY
- Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis
- (2019) Kim Newton et al. NATURE
- Multitasking Kinase RIPK1 Regulates Cell Death and Inflammation
- (2019) Kim Newton Cold Spring Harbor Perspectives in Biology
- A20 at the Crossroads of Cell Death, Inflammation, and Autoimmunity
- (2019) Arne Martens et al. Cold Spring Harbor Perspectives in Biology
- Nucleic Acid Sensors and Programmed Cell Death
- (2019) Jonathan Maelfait et al. JOURNAL OF MOLECULAR BIOLOGY
- Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis
- (2019) Xixi Zhang et al. Nature Communications
- K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation
- (2019) Yong Tang et al. Nature Communications
- Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
- (2019) Najoua Lalaoui et al. NATURE
- A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1
- (2019) Panfeng Tao et al. NATURE
- The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex
- (2018) Miguel Mompeán et al. CELL
- A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival
- (2018) Michael G. Kattah et al. JOURNAL OF EXPERIMENTAL MEDICINE
- PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation
- (2018) Seung-Won Choi et al. MOLECULAR CELL
- Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2
- (2018) Alessandro Annibaldi et al. MOLECULAR CELL
- UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
- (2018) Vyacheslav Akimov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis
- (2018) Huyan Meng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis
- (2018) Palak Amin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BiallelicRIPK1mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation
- (2018) Delphine Cuchet-Lourenço et al. SCIENCE
- CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing
- (2018) Marinella G. Callow et al. Cell Death & Disease
- Parkin regulates NF-κB by mediating site-specific ubiquitination of RIPK1
- (2018) Yu Wang et al. Cell Death & Disease
- UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
- (2018) Vyacheslav Akimov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1’s Cytotoxic Potential
- (2018) Rebecca Feltham et al. Cell Reports
- TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
- (2018) Daichao Xu et al. CELL
- OTULIN limits cell death and inflammation by deubiquitinating LUBAC
- (2018) Klaus Heger et al. NATURE
- LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
- (2018) Nieves Peltzer et al. NATURE
- TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation
- (2018) Elodie Lafont et al. NATURE CELL BIOLOGY
- Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
- (2018) Joseph Sarhan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases
- (2018) Yue Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
- (2018) Pontus Orning et al. SCIENCE
- RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense
- (2017) Lance W. Peterson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Embryonic Lethality and Host Immunity of RelA-Deficient Mice Are Mediated by Both Apoptosis and Necroptosis
- (2017) Chengxian Xu et al. JOURNAL OF IMMUNOLOGY
- MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death
- (2017) Isabel Jaco et al. MOLECULAR CELL
- p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection
- (2017) Manoj B. Menon et al. NATURE CELL BIOLOGY
- MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death
- (2017) Yves Dondelinger et al. NATURE CELL BIOLOGY
- ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC
- (2017) Slawomir A. Dziedzic et al. NATURE CELL BIOLOGY
- PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP
- (2017) Huibing Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis
- (2017) Jiefei Geng et al. Nature Communications
- RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
- (2017) Yingying Zhang et al. Nature Communications
- EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation
- (2017) Jaclyn S. Pearson et al. Nature Microbiology
- Necroptosis and Inflammation
- (2016) Kim Newton et al. Annual Review of Biochemistry
- Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling
- (2016) Christoph H. Emmerich et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- TLR and TNF-R1 activation of the MKK3/MKK6-p38 axis in macrophages is mediated by TPL-2 kinase
- (2016) M. J. Pattison et al. BIOCHEMICAL JOURNAL
- The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
- (2016) Rune Busk Damgaard et al. CELL
- K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo
- (2016) B Shutinoski et al. CELL DEATH AND DIFFERENTIATION
- Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death
- (2016) M Cristina de Almagro et al. CELL DEATH AND DIFFERENTIATION
- SPATA2 links CYLD to the TNF‐α receptor signaling complex and modulates the receptor signaling outcomes
- (2016) Sebastian A Wagner et al. EMBO JOURNAL
- SPATA2 promotes CYLD activity and regulates TNF‐induced NF‐κB signaling and cell death
- (2016) Lisa Schlicher et al. EMBO REPORTS
- IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1
- (2016) Christiane Koppe et al. HEPATOLOGY
- NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions
- (2016) Katerina Vlantis et al. IMMUNITY
- LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
- (2016) Julia Zinngrebe et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
- (2016) Paul R. Elliott et al. MOLECULAR CELL
- RIPK1 inhibits ZBP1-driven necroptosis during development
- (2016) Kim Newton et al. NATURE
- RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation
- (2016) Juan Lin et al. NATURE
- Proteogenomics connects somatic mutations to signalling in breast cancer
- (2016) Philipp Mertins et al. NATURE
- CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3
- (2016) Jinho Seo et al. NATURE CELL BIOLOGY
- Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
- (2016) Qing Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion
- (2016) Francesca Sacco et al. Nature Communications
- SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes
- (2016) Sebastian Kupka et al. Cell Reports
- Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis
- (2015) D A Rodriguez et al. CELL DEATH AND DIFFERENTIATION
- RIP1 Cleavage in the Kinase Domain Regulates TRAIL-Induced NF-κB Activation and Lymphoma Survival
- (2015) Laiqun Zhang et al. MOLECULAR AND CELLULAR BIOLOGY
- NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling
- (2015) Yves Dondelinger et al. MOLECULAR CELL
- Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
- (2015) Ingrid E. Wertz et al. NATURE
- Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease
- (2015) Qing Zhou et al. NATURE GENETICS
- Quantitative phosphoproteomic analysis of IL-33-mediated signaling
- (2015) Sneha M. Pinto et al. PROTEOMICS
- Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
- (2015) S. Liu et al. SCIENCE
- Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination
- (2015) M C de Almagro et al. Cell Death & Disease
- Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate
- (2015) Ramesh K. Krishnan et al. Nature Communications
- LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes
- (2015) Peter Draber et al. Cell Reports
- The deubiquitinase activity of A20 is dispensable for NF- B signaling
- (2014) A. De et al. EMBO REPORTS
- Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN
- (2014) Tsuyoshi Takiuchi et al. GENES TO CELLS
- Receptor-Interacting Protein Homotypic Interaction Motif-Dependent Control of NF- B Activation via the DNA-Dependent Activator of IFN Regulatory Factors
- (2014) W. J. Kaiser et al. JOURNAL OF IMMUNOLOGY
- Cathepsins Limit Macrophage Necroptosis through Cleavage of Rip1 Kinase
- (2014) S. McComb et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo
- (2014) Apostolos Polykratis et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice
- (2014) S. B. Berger et al. JOURNAL OF IMMUNOLOGY
- Binding of OTULIN to the PUB Domain of HOIP Controls NF-κB Signaling
- (2014) Veronique Schaeffer et al. MOLECULAR CELL
- Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
- (2014) Huayi Wang et al. MOLECULAR CELL
- Is SIRT2 required for necroptosis?
- (2014) Kim Newton et al. NATURE
- Necroptosis
- (2014) Andreas Linkermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF- B and MAPK signaling
- (2014) N. H. Philip et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
- (2014) Joanne M. Hildebrand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
- (2014) D. Weng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis
- (2014) K. Newton et al. SCIENCE
- TNF and MAP kinase signalling pathways
- (2014) Guadalupe Sabio et al. SEMINARS IN IMMUNOLOGY
- A Plug Release Mechanism for Membrane Permeation by MLKL
- (2014) Lijing Su et al. STRUCTURE
- HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death
- (2014) Nieves Peltzer et al. Cell Reports
- MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
- (2014) Yves Dondelinger et al. Cell Reports
- TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
- (2014) James A Rickard et al. eLife
- Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
- (2014) Snehlata Kumari et al. eLife
- Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis
- (2013) Thomas McQuade et al. BIOCHEMICAL JOURNAL
- OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin
- (2013) Kirstin Keusekotten et al. CELL
- RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
- (2013) Y Dondelinger et al. CELL DEATH AND DIFFERENTIATION
- TLR3 immunity to infection in mice and humans
- (2013) Shen-Ying Zhang et al. CURRENT OPINION IN IMMUNOLOGY
- Dimerization and Ubiquitin Mediated Recruitment of A20, a Complex Deubiquitinating Enzyme
- (2013) Timothy T. Lu et al. IMMUNITY
- The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
- (2013) James M. Murphy et al. IMMUNITY
- Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL
- (2013) William J. Kaiser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
- (2013) Elena Rivkin et al. NATURE
- Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains
- (2013) Shan Li et al. NATURE
- Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
- (2013) Benjamin Stieglitz et al. NATURE
- Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
- (2013) Zhenyu Cai et al. NATURE CELL BIOLOGY
- Integrated proteomic analysis of post-translational modifications by serial enrichment
- (2013) Philipp Mertins et al. NATURE METHODS
- CYLD Deubiquitinates RIP1 in the TNFα-Induced Necrosome to Facilitate Kinase Activation and Programmed Necrosis
- (2013) David M. Moquin et al. PLoS One
- Structural Insights into RIP3-Mediated Necroptotic Signaling
- (2013) Tian Xie et al. Cell Reports
- Inactivation of the Deubiquitinase CYLD in Hepatocytes Causes Apoptosis, Inflammation, Fibrosis, and Cancer
- (2012) Kostas Nikolaou et al. CANCER CELL
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- Intrinsic cleavage of receptor-interacting protein kinase-1 by caspase-6
- (2012) B J van Raam et al. CELL DEATH AND DIFFERENTIATION
- A Quantitative Map of the Liver Mitochondrial Phosphoproteome Reveals Posttranslational Control of Ketogenesis
- (2012) Paul A. Grimsrud et al. Cell Metabolism
- A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7
- (2012) Kelly Verhelst et al. EMBO JOURNAL
- Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation
- (2012) Fuminori Tokunaga et al. EMBO JOURNAL
- The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
- (2012) Judith J Smit et al. EMBO JOURNAL
- IAPs limit activation of RIP kinases by TNF receptor 1 during development
- (2012) Maryline Moulin et al. EMBO JOURNAL
- LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
- (2012) Benjamin Stieglitz et al. EMBO REPORTS
- Proteomic Analyses Reveal Divergent Ubiquitylation Site Patterns in Murine Tissues
- (2012) Sebastian A. Wagner et al. MOLECULAR & CELLULAR PROTEOMICS
- Refined Preparation and Use of Anti-diglycine Remnant (K-ε-GG) Antibody Enables Routine Quantification of 10,000s of Ubiquitination Sites in Single Proteomics Experiments
- (2012) Namrata D. Udeshi et al. MOLECULAR & CELLULAR PROTEOMICS
- TAK1 Is Essential for Osteoclast Differentiation and Is an Important Modulator of Cell Death by Apoptosis and Necroptosis
- (2012) Betty Lamothe et al. MOLECULAR AND CELLULAR BIOLOGY
- The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
- (2012) Nisha Narayan et al. NATURE
- Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
- (2012) J. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RIG-I RNA Helicase Activation of IRF3 Transcription Factor Is Negatively Regulated by Caspase-8-Mediated Cleavage of the RIP1 Protein
- (2011) Akhil Rajput et al. IMMUNITY
- Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome
- (2011) Woong Kim et al. MOLECULAR CELL
- SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
- (2011) Fuminori Tokunaga et al. NATURE
- SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
- (2011) Fumiyo Ikeda et al. NATURE
- Linear ubiquitination prevents inflammation and regulates immune signalling
- (2011) Björn Gerlach et al. NATURE
- c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling
- (2010) Jasmin N Dynek et al. EMBO JOURNAL
- Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling
- (2010) Ivan Bosanac et al. MOLECULAR CELL
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
- (2009) Sudan He et al. CELL
- Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation
- (2009) Simin Rahighi et al. CELL
- RIPK1 is not essential for TNFR1-induced activation of NF-κB
- (2009) W W-L Wong et al. CELL DEATH AND DIFFERENTIATION
- DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-κB
- (2009) Manuele Rebsamen et al. EMBO REPORTS
- Structural Basis for Recognition of Diubiquitins by NEMO
- (2009) Yu-Chih Lo et al. MOLECULAR CELL
- Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
- (2009) Tobias L. Haas et al. MOLECULAR CELL
- Involvement of linear polyubiquitylation of NEMO in NF-κB activation
- (2009) Fuminori Tokunaga et al. NATURE CELL BIOLOGY
- TNF-α Induces Two Distinct Caspase-8 Activation Pathways
- (2008) Lai Wang et al. CELL
- Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
- (2008) Junichi Hitomi et al. CELL
- Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series
- (2008) Fumiyo Ikeda et al. EMBO REPORTS
- TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway
- (2008) Marie-Cécile Michallet et al. IMMUNITY
- c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factor α (TNFα)-induced NF-κB Activation
- (2008) Eugene Varfolomeev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination
- (2008) Mathieu J.M. Bertrand et al. MOLECULAR CELL
- Identification of RIP1 kinase as a specific cellular target of necrostatins
- (2008) Alexei Degterev et al. Nature Chemical Biology
- The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
- (2008) Yelena L Pobezinskaya et al. NATURE IMMUNOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started