OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice
出版年份 2021 全文链接
标题
OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice
作者
关键词
-
出版物
Nature Communications
Volume 12, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-10-09
DOI
10.1038/s41467-021-25945-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity
- (2021) Esther Hoste et al. Nature Communications
- OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis
- (2020) Lien Verboom et al. Cell Reports
- OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer
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- Keratinocyte-specific deletion of SHARPIN induces atopic dermatitis-like inflammation in mice
- (2020) John P. Sundberg et al. PLoS One
- OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell death
- (2019) Rune Busk Damgaard et al. EMBO Molecular Medicine
- OTULIN limits cell death and inflammation by deubiquitinating LUBAC
- (2018) Klaus Heger et al. NATURE
- LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
- (2018) Nieves Peltzer et al. NATURE
- LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
- (2018) Lucia Taraborrelli et al. Nature Communications
- Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation
- (2017) Sjoerd J. L. van Wijk et al. Nature Microbiology
- The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
- (2016) Rune Busk Damgaard et al. CELL
- Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
- (2016) Qing Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice
- (2015) Katerina Vlantis et al. GUT
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- Binding of OTULIN to the PUB Domain of HOIP Controls NF-κB Signaling
- (2014) Veronique Schaeffer et al. MOLECULAR CELL
- Molecular Basis and Regulation of OTULIN-LUBAC Interaction
- (2014) Paul R. Elliott et al. MOLECULAR CELL
- RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
- (2014) Marius Dannappel et al. NATURE
- Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis
- (2014) K. Newton et al. SCIENCE
- HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death
- (2014) Nieves Peltzer et al. Cell Reports
- TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
- (2014) James A Rickard et al. eLife
- Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
- (2014) Snehlata Kumari et al. eLife
- OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin
- (2013) Kirstin Keusekotten et al. CELL
- Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium
- (2013) Filip Van Hauwermeiren et al. JOURNAL OF CLINICAL INVESTIGATION
- The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
- (2013) Elena Rivkin et al. NATURE
- Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
- (2013) C. H. Emmerich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation
- (2011) Marion C. Bonnet et al. IMMUNITY
- SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
- (2011) Fuminori Tokunaga et al. NATURE
- FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
- (2011) Patrick-Simon Welz et al. NATURE
- SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
- (2011) Fumiyo Ikeda et al. NATURE
- Linear ubiquitination prevents inflammation and regulates immune signalling
- (2011) Björn Gerlach et al. NATURE
- Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
- (2009) Tobias L. Haas et al. MOLECULAR CELL
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