Peptide-decorated nanocarriers penetrating the blood-brain barrier for imaging and therapy of brain diseases

Screening on-chip fabricated nanoparticles for penetrating the blood–brain barrier

(2022) Qinghong Hou et al.   Nanoscale

Glymphatic System and Subsidiary Pathways Drive Nanoparticles Away from the Brain

(2022) Rui Liu et al.   Research

Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies

(2021) Liang Han et al.   Acta Pharmaceutica Sinica B

Strategies for delivering therapeutics across the blood–brain barrier

(2021) Georg C. Terstappen et al.   NATURE REVIEWS DRUG DISCOVERY

Blood-brain barrier opening with focused ultrasound in Parkinson’s disease dementia

(2021) Carmen Gasca-Salas et al.   Nature Communications

Unmasking CSF protein corona: Effect on targeting capacity of nanoparticles

(2021) Yazhen Wang et al.   JOURNAL OF CONTROLLED RELEASE

Ferritin: A Multifunctional Nanoplatform for Biological Detection, Imaging Diagnosis, and Drug Delivery

(2021) Ningning Song et al.   ACCOUNTS OF CHEMICAL RESEARCH

Multifunctional Selenium Quantum Dots for the Treatment of Alzheimer’s Disease by Reducing Aβ-Neurotoxicity and Oxidative Stress and Alleviate Neuroinflammation

(2021) Xian Guo et al.   ACS Applied Materials & Interfaces

Regulation of in vivo delivery of nanomedicines by herbal medicines

(2021) Juan Guan et al.   ADVANCED DRUG DELIVERY REVIEWS

Interrogating preclinical study of liposomes: The effect of mouse strain reexamined

(2021) Juan Guan et al.   JOURNAL OF CONTROLLED RELEASE

Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors

(2021) Roger L. Papke et al.   PHARMACOLOGICAL REVIEWS

Nicotinic acetylcholine receptor redux: Discovery of accessories opens therapeutic vistas

(2021) Jose A. Matta et al.   SCIENCE

Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction

(2021) Fuyuko Takata et al.   Frontiers in Cellular Neuroscience

RVG-functionalized reduction sensitive micelles for the effective accumulation of doxorubicin in brain

(2021) Jiangkang Xu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Development of Novel Therapeutics Targeting the Blood–Brain Barrier: From Barrier to Carrier

(2021) Jia Li et al.   Advanced Science

Benefit of a Short Chain Peptide as a Targeting Ligand of Nanocarriers for a Brain-Driven Purpose

(2021) Yu-Chen Lo et al.   Pharmaceutics

Color-convertible fluorescent nanoprobe for Parkinson’s disease diagnosis

(2021) Jiapei Yang et al.   CHEMICAL ENGINEERING JOURNAL

Modular design of multifunctional core-shell tecto dendrimers complexed with copper(II) for MR imaging-guided chemodynamic therapy of orthotopic glioma

(2021) Cong Song et al.   Nano Today

Structural, Molecular, and Functional Alterations of the Blood-Brain Barrier during Epileptogenesis and Epilepsy: A Cause, Consequence, or Both?

(2020) Wolfgang Löscher et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

(2020) Xiangqi Meng et al.   Nature Communications

Endo/Lysosome‐Escapable Delivery Depot for Improving BBB Transcytosis and Neuron Targeted Therapy of Alzheimer's Disease

(2020) Lulu Cai et al.   ADVANCED FUNCTIONAL MATERIALS

Single siRNA Nanocapsules for Effective siRNA Brain Delivery and Glioblastoma Treatment

(2020) Yan Zou et al.   ADVANCED MATERIALS

Brain control of humoral immune responses amenable to behavioural modulation

(2020) Xu Zhang et al.   NATURE

Matrix metalloprotein-triggered, cell penetrating peptide-modified star-shaped nanoparticles for tumor targeting and cancer therapy

(2020) Fangyuan Guo et al.   JOURNAL OF NANOBIOTECHNOLOGY

Engineered Cell‐Membrane‐Coated Nanoparticles Directly Present Tumor Antigens to Promote Anticancer Immunity

(2020) Yao Jiang et al.   ADVANCED MATERIALS

Clearance of two organic nanoparticles from the brain via the paravascular pathway

(2020) Xiao Gu et al.   JOURNAL OF CONTROLLED RELEASE

Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human

(2020) Wandong Zhang et al.   Fluids and Barriers of the CNS

Designing peptide nanoparticles for efficient brain delivery

(2020) Aroa Duro-Castano et al.   ADVANCED DRUG DELIVERY REVIEWS

Pre-treatment with high molecular weight free PEG effectively suppresses anti-PEG antibody induction by PEG-liposomes in mice

(2020) Morgan D. McSweeney et al.   JOURNAL OF CONTROLLED RELEASE

Consistent opening of the blood brain barrier using focused ultrasound with constant intravenous infusion of microbubble agent

(2020) Norman A. Lapin et al.   Scientific Reports

Remodeling tumor immune microenvironment (TIME) for glioma therapy using multi-targeting liposomal codelivery

(2020) Zening Zheng et al.   Journal for ImmunoTherapy of Cancer

An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy

(2020) Cong Wang et al.   Nature Biomedical Engineering

Enhanced Cancer-targeted Drug Delivery Using Precoated Nanoparticles

(2020) Lu Yu et al.   NANO LETTERS

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

Targeted exosome coating gene-chem nanocomplex as “nanoscavenger” for clearing α-synuclein and immune activation of Parkinson’s disease

(2020) Linying Liu et al.   Science Advances

Anti-PEG scFv corona ameliorates accelerated blood clearance phenomenon of PEGylated nanomedicines

(2020) Zui Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Seizure-induced microvascular injury is associated with impaired neurovascular coupling and blood-brain barrier dysfunction

(2019) Ofer Prager et al.   EPILEPSIA

Holo-Lactoferrin Modified Liposome for Relieving Tumor Hypoxia and Enhancing Radiochemotherapy of Cancer

(2019) Zheng Zhang et al.   Small

Aggregation-Induced Absorption Enhancement for Deep Near-Infrared II Photoacoustic Imaging of Brain Gliomas In Vivo

(2019) Yajing Liu et al.   Advanced Science

Brain metastases

(2019) Achal Singh Achrol et al.   Nature Reviews Disease Primers

Embryonic Stem Cells‐Derived Exosomes Endowed with Targeting Properties as Chemotherapeutics Delivery Vehicles for Glioblastoma Therapy

(2019) Qingwei Zhu et al.   Advanced Science

Chlorotoxin peptide-functionalized polyethylenimine-entrapped gold nanoparticles for glioma SPECT/CT imaging and radionuclide therapy

(2019) Lingzhou Zhao et al.   JOURNAL OF NANOBIOTECHNOLOGY

Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance

(2019) Jonathan Cooper et al.   CANCER CELL

A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System

(2019) Di Wu et al.   ADVANCED MATERIALS

Ligand-Modified Cell Membrane Enables the Targeted Delivery of Drug Nanocrystals to Glioma

(2019) Zhilan Chai et al.   ACS Nano

Peptide-mediated drug delivery across the blood-brain barrier for targeting brain tumors

(2019) Behzad Jafari et al.   Expert Opinion on Drug Delivery

Sequentially Site-Specific Delivery of Thrombolytics and Neuroprotectant for Enhanced Treatment of Ischemic Stroke

(2019) Jianpei Xu et al.   ACS Nano

Amyloid Beta 25–35 induces blood-brain barrier disruption in vitro

(2019) Elvis Cuevas et al.   METABOLIC BRAIN DISEASE

Targeting the transferrin receptor for brain drug delivery

(2019) Kasper Bendix Johnsen et al.   PROGRESS IN NEUROBIOLOGY

High availability of the α7 nicotinic acetylcholine receptor in brains of individuals with mild cognitive impairment: A pilot study using 18F-ASEM PET

(2019) Jennifer M. Coughlin et al.   JOURNAL OF NUCLEAR MEDICINE

The blood-brain barrier: Physiology and strategies for drug delivery

(2019) Rucha Pandit et al.   ADVANCED DRUG DELIVERY REVIEWS

Cancer Cell Membrane‐Coated Nanoparticles for Personalized Therapy in Patient‐Derived Xenograft Models

(2019) Lang Rao et al.   ADVANCED FUNCTIONAL MATERIALS

Manipulation of Mitophagy by “All-in-One” nanosensitizer augments sonodynamic glioma therapy

(2019) Fei Qu et al.   Autophagy

Overcoming anti-PEG antibody mediated accelerated blood clearance of PEGylated liposomes by pre-infusion with high molecular weight free PEG

(2019) Morgan D. McSweeney et al.   JOURNAL OF CONTROLLED RELEASE

Brain-targeted drug delivery by manipulating protein corona functions

(2019) Zui Zhang et al.   Nature Communications

Lipoprotein receptor signalling in atherosclerosis

(2019) Chieko Mineo   CARDIOVASCULAR RESEARCH

Evaluation of sodium valproate loaded nanoparticles in acute and chronic pentylenetetrazole induced seizure models

(2019) Meenakshi Meenu et al.   EPILEPSY RESEARCH

Target delivery selective CSF-1R inhibitor to tumor-associated macrophages via erythrocyte-cancer cell hybrid membrane camouflaged pH-responsive copolymer micelle for cancer immunotherapy

(2019) Yuchi Wang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Systemic delivery of microRNA-21 antisense oligonucleotides to the brain using T7-peptide decorated exosomes

(2019) Gyeungyun Kim et al.   JOURNAL OF CONTROLLED RELEASE

Targeted Brain Delivery of Rabies Virus Glycoprotein 29-Modified Deferoxamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Mice

(2018) Linhao You et al.   ACS Nano

Nanoenzyme-Augmented Cancer Sonodynamic Therapy by Catalytic Tumor Oxygenation

(2018) Piao Zhu et al.   ACS Nano

Ferritin Nanocarrier Traverses the Blood Brain Barrier and Kills Glioma

(2018) Kelong Fan et al.   ACS Nano

Evolution of Nanoparticle Protein Corona across the Blood–Brain Barrier

(2018) Alysia Cox et al.   ACS Nano

Traceable Nanoparticles with Dual Targeting and ROS Response for RNAi-Based Immunochemotherapy of Intracranial Glioblastoma Treatment

(2018) Chenmeng Qiao et al.   ADVANCED MATERIALS

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

(2018) Tian Tian et al.   BIOMATERIALS

Peptide Mediated Brain Delivery of Nano- and Submicroparticles: A Synergistic Approach

(2018) Mark McCully et al.   CURRENT PHARMACEUTICAL DESIGN

Bridging barriers: a comparative look at the blood–brain barrier across organisms

(2018) Natasha M. O'Brown et al.   GENES & DEVELOPMENT

A minimal physiologically based pharmacokinetic model that predicts anti-PEG IgG-mediated clearance of PEGylated drugs in human and mouse

(2018) M.D. McSweeney et al.   JOURNAL OF CONTROLLED RELEASE

Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

(2018) Yu Zhang et al.   NANO LETTERS

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

A review of potential applications of MR-guided focused ultrasound for targeting brain tumor therapy

(2018) Layton Lamsam et al.   Neurosurgical Focus

Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

(2018) Nir Lipsman et al.   Nature Communications

Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins

(2018) Xihui Gao et al.   Theranostics

Listening in on the Microbubble Crowd: Advanced Acoustic Monitoring for Improved Control of Blood-Brain Barrier Opening with Focused Ultrasound

(2018) Catherine M. Gorick et al.   Theranostics

Integrin Clustering Matters: A Review of Biomaterials Functionalized with Multivalent Integrin-Binding Ligands to Improve Cell Adhesion, Migration, Differentiation, Angiogenesis, and Biomedical Device Integration

(2018) Fatemeh Karimi et al.   Advanced Healthcare Materials

Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma

(2018) Wing Yin Tong et al.   JOURNAL OF NANOBIOTECHNOLOGY

Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types

(2018) Longfa Kou et al.   Frontiers in Pharmacology

Focused Ultrasound-Augmented Delivery of Biodegradable Multifunctional Nanoplatforms for Imaging-Guided Brain Tumor Treatment

(2018) Meiying Wu et al.   Advanced Science

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

(2018) Denzil Furtado et al.   ADVANCED MATERIALS

Evidence for peri-ictal blood–brain barrier dysfunction in patients with epilepsy

(2018) Theodor Rüber et al.   BRAIN

Dopamine-loaded blood exosomes targeted to brain for better treatment of Parkinson's disease

(2018) Mengke Qu et al.   JOURNAL OF CONTROLLED RELEASE

Leutusome: A Biomimetic Nanoplatform Integrating Plasma Membrane Components of Leukocytes and Tumor Cells for Remarkably Enhanced Solid Tumor Homing

(2018) Hongliang He et al.   NANO LETTERS

Enhanced immunocompatibility of ligand-targeted liposomes by attenuating natural IgM absorption

(2018) Juan Guan et al.   Nature Communications

D-T7 Peptide-Modified PEGylated Bilirubin Nanoparticles Loaded with Cediranib and Paclitaxel for Antiangiogenesis and Chemotherapy of Glioma

(2018) Meinan Yu et al.   ACS Applied Materials & Interfaces

Recent progress of drug nanoformulations targeting to brain

(2018) Abdur Rauf Khan et al.   JOURNAL OF CONTROLLED RELEASE

Peptide-decorated polymeric nanomedicines for precision cancer therapy

(2018) Huanli Sun et al.   JOURNAL OF CONTROLLED RELEASE

Basement membrane and blood–brain barrier

(2018) Lingling Xu et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Dual-targeting and microenvironment-responsive micelles as a gene delivery system to improve the sensitivity of glioma to radiotherapy

(2018) Xiuxiu Jiao et al.   Acta Pharmaceutica Sinica B

Effect of high intensity focused ultrasound (HIFU) in conjunction with a nanomedicines-microbubble complex for enhanced drug delivery

(2017) Hyounkoo Han et al.   JOURNAL OF CONTROLLED RELEASE

Perfluoroarene–Based Peptide Macrocycles to Enhance Penetration Across the Blood–Brain Barrier

(2017) Colin M. Fadzen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evolution of the nanoparticle corona

(2017) Marilena Hadjidemetriou et al.   Nature Nanotechnology

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

(2017) Jingwei Xue et al.   Nature Nanotechnology

Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

(2017) Benjamin J. Andreone et al.   NEURON

Cell-Penetrating Peptides: From Basic Research to Clinics

(2017) Giulia Guidotti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease

(2017) Aman P. Mann et al.   Nature Communications

Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery

(2017) Yingzhi Chen et al.   Theranostics

472PPHASE 1/2A STUDY OF GLUTATHIONE PEGYLATED LIPOSOMAL DOXORUBICIN (2B3-101) IN PATIENTS WITH BRAIN METASTASES (BM) FROM SOLID TUMORS OR RECURRENT HIGH GRADE GLIOMAS (HGG)

(2017) D. Brandsma et al.   ANNALS OF ONCOLOGY

Penetratin Peptide-Functionalized Gold Nanostars: Enhanced BBB Permeability and NIR Photothermal Treatment of Alzheimer’s Disease Using Ultralow Irradiance

(2016) Tiantian Yin et al.   ACS Applied Materials & Interfaces

Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries

(2016) Ester J. Kwon et al.   ACS Nano

Exploring Cellular Interactions of Liposomes Using Protein Corona Fingerprints and Physicochemical Properties

(2016) Arafeh Bigdeli et al.   ACS Nano

Adding Functions to Biomaterial Surfaces through Protein Incorporation

(2016) Małgorzata A. Wronska et al.   ADVANCED MATERIALS

Controlling the Stealth Effect of Nanocarriers through Understanding the Protein Corona

(2016) Susanne Schöttler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modeling Development and Disease with Organoids

(2016) Hans Clevers   CELL

Blood–brain barrier shuttle peptides: an emerging paradigm for brain delivery

(2016) Benjamí Oller-Salvia et al.   CHEMICAL SOCIETY REVIEWS

Design and Fabrication of Plasmonic Nanomaterials Based on Gold Nanorod Supercrystals

(2016) Leonardo Scarabelli et al.   CHEMISTRY OF MATERIALS

A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer

(2016) C. E. S. Hoogstins et al.   CLINICAL CANCER RESEARCH

Small endogenous molecules as moiety to improve targeting of CNS drugs

(2016) Flavia Maria Sutera et al.   Expert Opinion on Drug Delivery

Brain tumor-targeted therapy by systemic delivery of siRNA with Transferrin receptor-mediated core-shell nanoparticles

(2016) Lin Wei et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke

(2016) Shanyan Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glutamate-Mediated Blood-Brain Barrier Opening: Implications for Neuroprotection and Drug Delivery

(2016) U. Vazana et al.   JOURNAL OF NEUROSCIENCE

Glutamate Induces Blood–Brain Barrier Permeability through Activation of N -Methyl-D-Aspartate Receptors

(2016) Kristiana Xhima et al.   JOURNAL OF NEUROSCIENCE

Recent advances in mass spectrometric analysis of protein deamidation

(2016) Piliang Hao et al.   MASS SPECTROMETRY REVIEWS

The effect of nanoparticle size on in vivo pharmacokinetics and cellular interaction

(2016) Nazanin Hoshyar et al.   Nanomedicine

High-performance iron oxide nanoparticles for magnetic particle imaging – guided hyperthermia (hMPI)

(2016) Lisa M. Bauer et al.   Nanoscale

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

(2016) William A. Banks   NATURE REVIEWS DRUG DISCOVERY

Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Efficient Intratumoral Diffusion and Synthesized Anti-Glioma Therapy

(2016) Yayuan Liu et al.   Theranostics

AD-Peptide Ligand of Nicotine Acetylcholine Receptors for Brain-Targeted Drug Delivery

(2015) Xiaoli Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Applying the Retro-Enantio Approach To Obtain a Peptide Capable of Overcoming the Blood-Brain Barrier

(2015) Roger Prades et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single-component self-assembled RNAi nanoparticles functionalized with tumor-targeting iNGR delivering abundant siRNA for efficient glioma therapy

(2015) Sai An et al.   BIOMATERIALS

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Peptide stapling techniques based on different macrocyclisation chemistries

(2015) Yu Heng Lau et al.   CHEMICAL SOCIETY REVIEWS

A new mechanism of thermal sensitivity for rapid drug release and low systemic toxicity in hyperthermia and thermal ablation temperature ranges

(2015) Ali Dabbagh et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications

(2015) Vera A. Khokhlova et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Shape and size-dependent immune response to antigen-carrying nanoparticles

(2015) Sunny Kumar et al.   JOURNAL OF CONTROLLED RELEASE

Transcriptional Regulators of Claudins in Epithelial Tight Junctions

(2015) Niamat Khan et al.   MEDIATORS OF INFLAMMATION

Nanoparticle biointerfacing by platelet membrane cloaking

(2015) Che-Ming J. Hu et al.   NATURE

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

(2015) Zhen Zhao et al.   NATURE NEUROSCIENCE

SLC transporters as therapeutic targets: emerging opportunities

(2015) Lawrence Lin et al.   NATURE REVIEWS DRUG DISCOVERY

Current status and future directions of anti-angiogenic therapy for gliomas

(2015) Wolfgang Wick et al.   NEURO-ONCOLOGY

Cell-penetrating peptides transport therapeutics into cells

(2015) Joshua D. Ramsey et al.   PHARMACOLOGY & THERAPEUTICS

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

Advances and Challenges of Liposome Assisted Drug Delivery

(2015) Lisa Sercombe et al.   Frontiers in Pharmacology

Abstract CT216: Phase I dose escalating study of 2B3-101, glutathione PEGylated liposomal doxorubicin, in patients with solid tumors and brain metastases or recurrent malignant glioma

(2015) Pieter J. Gaillard et al.   CANCER RESEARCH

Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting

(2014) Yayuan Liu et al.   BIOMATERIALS

iNGR-modified PEG-PLGA nanoparticles that recognize tumor vasculature and penetrate gliomas

(2014) Ting Kang et al.   BIOMATERIALS

Effect of HIFU treatment on tumor targeting efficacy of docetaxel-loaded Pluronic nanoparticles

(2014) Keun Sang Oh et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Cell-Based in Vitro Blood–Brain Barrier Model Can Rapidly Evaluate Nanoparticles’ Brain Permeability in Association with Particle Size and Surface Modification

(2014) Sanshiro Hanada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comparison of active, passive and magnetic targeting to tumors of multifunctional paclitaxel/SPIO-loaded nanoparticles for tumor imaging and therapy

(2014) Nathalie Schleich et al.   JOURNAL OF CONTROLLED RELEASE

Synergistic Dual-Ligand Doxorubicin Liposomes Improve Targeting and Therapeutic Efficacy of Brain Glioma in Animals

(2014) Taili Zong et al.   MOLECULAR PHARMACEUTICS

Increased Brain Penetration and Potency of a Therapeutic Antibody Using a Monovalent Molecular Shuttle

(2014) Jens Niewoehner et al.   NEURON

Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101)

(2014) Pieter J. Gaillard et al.   PLoS One

Current challenges in peptide-based drug discovery

(2014) Laszlo Otvos et al.   Frontiers in Chemistry

LDLR-mediated peptide-22-conjugated nanoparticles for dual-targeting therapy of brain glioma

(2013) Bo Zhang et al.   BIOMATERIALS

Phase I Study of GRN1005 in Recurrent Malignant Glioma

(2013) J. Drappatz et al.   CLINICAL CANCER RESEARCH

Profiling Solute Carrier Transporters in the Human Blood–Brain Barrier

(2013) E G Geier et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Advances in brain drug targeting and delivery: limitations and challenges of solid lipid nanoparticles

(2013) Medha Patel et al.   Expert Opinion on Drug Delivery

Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood–brain barrier divide

(2013) Ann-Marie Chacko et al.   Expert Opinion on Drug Delivery

Cell penetrating peptide tethered bi-ligand liposomes for delivery to brain in vivo: Biodistribution and transfection

(2013) Gitanjali Sharma et al.   JOURNAL OF CONTROLLED RELEASE

The role of claudin-5 in blood-brain barrier (BBB) and brain metastases (Review)

(2013) WANG JIA et al.   Molecular Medicine Reports

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Power failure: why small sample size undermines the reliability of neuroscience

(2013) Katherine S. Button et al.   NATURE REVIEWS NEUROSCIENCE

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

(2013) P. Kolhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoprobes Visualizing Gliomas by Crossing the Blood Brain Tumor Barrier

(2013) Xihui Gao et al.   Small

Assessing the barriers to image-guided drug delivery

(2013) Gregory M. Lanza et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases

(2013) Konstantinos K. Tsilidis et al.   PLOS BIOLOGY

Metabolism of Nanomaterials in Vivo: Blood Circulation and Organ Clearance

(2012) Bing Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

The blood-brain barrier in health and disease

(2012) Richard Daneman   ANNALS OF NEUROLOGY

Gene and doxorubicin co-delivery system for targeting therapy of glioma

(2012) Shuhuan Liu et al.   BIOMATERIALS

Therapeutic Benefits from Nanoparticles: The Potential Significance of Nanoscience in Diseases with Compromise to the Blood Brain Barrier

(2012) Silke Krol et al.   CHEMICAL REVIEWS

Drug Transport across the Blood–Brain Barrier

(2012) William M Pardridge   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Designing the nanoparticle–biomolecule interface for “targeting and therapeutic delivery”

(2012) Eugene Mahon et al.   JOURNAL OF CONTROLLED RELEASE

Magnetoferritin nanoparticles for targeting and visualizing tumour tissues

(2012) Kelong Fan et al.   Nature Nanotechnology

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

How Shape Influences Uptake: Interactions of Anisotropic Polymer Nanoparticles and Human Mesenchymal Stem Cells

(2012) Laura Florez et al.   Small

Why Integrin as a Primary Target for Imaging and Therapy

(2012) Gang Niu et al.   Theranostics

Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents

(2011) Laura Biddlestone-Thorpe et al.   ADVANCED DRUG DELIVERY REVIEWS

Drug delivery to the brain in Alzheimer's disease: Consideration of the blood–brain barrier

(2011) William A. Banks   ADVANCED DRUG DELIVERY REVIEWS

Micelle-Based Brain-Targeted Drug Delivery Enabled by a Nicotine Acetylcholine Receptor Ligand

(2011) Changyou Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A brain-targeted rabies virus glycoprotein-disulfide linked PEI nanocarrier for delivery of neurogenic microRNA

(2011) Do Won Hwang et al.   BIOMATERIALS

Liposome formulated with TAT-modified cholesterol for enhancing the brain delivery

(2011) Yao Qin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Novel 64Cu- and 68Ga-Labeled RGD Conjugates Show Improved PET Imaging of    3 Integrin Expression and Facile Radiosynthesis

(2011) R. A. Dumont et al.   JOURNAL OF NUCLEAR MEDICINE

Cancer theranostics: the rise of targeted magnetic nanoparticles

(2011) Adam J. Cole et al.   TRENDS IN BIOTECHNOLOGY

Toxicity and interaction of titanium dioxide nanoparticles with microtubule protein

(2010) Z. N. Gheshlaghi et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Endocytosis of nanomedicines

(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid-  in a Mouse Model of Alzheimer's Disease

(2010) A. M. S. Hartz et al.   MOLECULAR PHARMACOLOGY

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular insights and therapeutic targets for blood–brain barrier disruption in ischemic stroke: Critical role of matrix metalloproteinases and tissue-type plasminogen activator

(2010) Rong Jin et al.   NEUROBIOLOGY OF DISEASE

Brain-targeting gene delivery and cellular internalization mechanisms for modified rabies virus glycoprotein RVG29 nanoparticles

(2009) Yang Liu et al.   BIOMATERIALS

What does the cell see?

(2009) Iseult Lynch et al.   Nature Nanotechnology

Size Effect on Cell Uptake in Well-Suspended, Uniform Mesoporous Silica Nanoparticles

(2009) Fang Lu et al.   Small

Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease

(2008) Barnabas Wilson et al.   BRAIN RESEARCH

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Nanoparticle-mediated cellular response is size-dependent

(2008) Wen Jiang et al.   Nature Nanotechnology

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bio-distribution and metabolic paths of silica coated CdSeS quantum dots

(2008) Zhen Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY