Integrin Clustering Matters: A Review of Biomaterials Functionalized with Multivalent Integrin-Binding Ligands to Improve Cell Adhesion, Migration, Differentiation, Angiogenesis, and Biomedical Device Integration

The development of polymeric biomaterials inspired by the extracellular matrix

(2017) Daniel E. Heath et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Corrigendum: Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second

(2017) Nico Strohmeyer et al.   NATURE MATERIALS

Decellularized extracellular matrices produced from immortal cell lines derived from different parts of the placenta support primary mesenchymal stem cell expansion

(2017) Gina D. Kusuma et al.   PLoS One

A novel bioreactor system for biaxial mechanical loading enhances the properties of tissue-engineered human cartilage

(2017) Christoph Meinert et al.   Scientific Reports

Nano-scale clustering of integrin-binding ligands regulates endothelial cell adhesion, migration, and endothelialization rate: novel materials for small diameter vascular graft applications

(2017) Fatemeh Karimi et al.   Journal of Materials Chemistry B

Use of protein-engineered fabrics to identify design rules for integrin ligand clustering in biomaterials

(2016) Patrick L. Benitez et al.   Integrative Biology

Engineering Immunomodulatory Biomaterials To Tune the Inflammatory Response

(2016) Ajaykumar Vishwakarma et al.   TRENDS IN BIOTECHNOLOGY

Selective binding and lateral clustering of α5β1 and αvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly

(2016) Viktoria Schaufler et al.   Cell Adhesion & Migration

Interplay of Matrix Stiffness and Cell–Cell Contact in Regulating Differentiation of Stem Cells

(2015) Kai Ye et al.   ACS Applied Materials & Interfaces

An overview of injectable polymeric hydrogels for tissue engineering

(2015) A. Sivashanmugam et al.   EUROPEAN POLYMER JOURNAL

Effects of Nanoscale Spatial Arrangement of Arginine–Glycine–Aspartate Peptides on Dedifferentiation of Chondrocytes

(2015) Shiyu Li et al.   NANO LETTERS

Fabrication of RGD Micro/Nanopattern and Corresponding Study of Stem Cell Differentiation

(2015) Xuan Wang et al.   NANO LETTERS

Matrix Stiffness and Nanoscale Spatial Organization of Cell-Adhesive Ligands Direct Stem Cell Fate

(2015) Kai Ye et al.   NANO LETTERS

Effects of RGD nanospacing on chondrogenic differentiation of mesenchymal stem cells

(2015) Zhenhua Li et al.   Journal of Materials Chemistry B

Nanoscale Integrin Ligand Patterns Determine Melanoma Cell Behavior

(2014) Katharina Amschler et al.   ACS Nano

Integrins regulate epithelial cell differentiation by modulating Notch activity

(2014) M. J. Gomez-Lamarca et al.   JOURNAL OF CELL SCIENCE

A Photoactivatable Nanopatterned Substrate for Analyzing Collective Cell Migration with Precisely Tuned Cell-Extracellular Matrix Ligand Interactions

(2014) Yoshihisa Shimizu et al.   PLoS One

Multivalent glycoconjugates as vaccines and potential drug candidates

(2014) Sumati Bhatia et al.   MedChemComm

Modulation of Stem Cell Adhesion and Morphology via Facile Control over Surface Presentation of Cell Adhesion Molecules

(2013) Haiqing Li et al.   BIOMACROMOLECULES

Effect of RGD nanospacing on differentiation of stem cells

(2013) Xuan Wang et al.   BIOMATERIALS

Surface engineering of cardiovascular stent with endothelial cell selectivity for in vivo re-endothelialisation

(2013) Yu Wei et al.   BIOMATERIALS

Signalling pathways linking integrins with cell cycle progression

(2013) Paulina Moreno-Layseca et al.   MATRIX BIOLOGY

Adhesion, proliferation, and differentiation of mesenchymal stem cells on RGD nanopatterns of varied nanospacings

(2013) Xuan Wang et al.   Organogenesis

Bioreactor-Induced Chondrocyte Maturation Is Dependent on Cell Passage and Onset of Loading

(2013) Ning Wang et al.   Cartilage

Design and characterization of sulfobetaine-containing terpolymer biomaterials

(2012) Daniel E. Heath et al.   Acta Biomaterialia

Functionalizing αvβ3- or α5β1-Selective Integrin Antagonists for Surface Coating: A Method To Discriminate Integrin Subtypes In Vitro

(2012) Florian Rechenmacher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The significance of integrin ligand nanopatterning on lipid raft clustering in hematopoietic stem cells

(2012) Eva Altrock et al.   BIOMATERIALS

Assembly and disassembly of cell matrix adhesions

(2012) Bernhard Wehrle-Haller   CURRENT OPINION IN CELL BIOLOGY

Endothelial cell adhesion and proliferation to PEGylated polymers with covalently linked RGD peptides

(2012) Xin Wang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Zwitterionic polycarboxybetaine coating functionalized with REDV peptide to improve selectivity for endothelial cells

(2012) Ying Ji et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Lateral spacing of adhesion peptides influences human mesenchymal stem cell behaviour

(2012) J. E. Frith et al.   JOURNAL OF CELL SCIENCE

In Vitro Endothelialization of Electrospun Terpolymer Scaffolds: Evaluation of Scaffold Type and Cell Source

(2012) Daniel E. Heath et al.   TISSUE ENGINEERING PART A

Thinking outside the cell: how cadherins drive adhesion

(2012) Julia Brasch et al.   TRENDS IN CELL BIOLOGY

Nanopatterning Biomolecules by Block Copolymer Self-Assembly

(2012) Kato L. Killops et al.   ACS Macro Letters

Engineered Bivalent Ligands to Bias ErbB Receptor-mediated Signaling and Phenotypes

(2011) Steven M. Jay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor

(2011) Soo-Hyun Kim et al.   JOURNAL OF ENDOCRINOLOGY

Integrin organization: Linking adhesion ligand nanopatterns with altered cell responses

(2011) W.A. Comisar et al.   JOURNAL OF THEORETICAL BIOLOGY

Nanolithographic Control of the Spatial Organization of Cellular Adhesion Receptors at the Single-Molecule Level

(2011) Mark Schvartzman et al.   NANO LETTERS

Biofunctionalization of materials for implants using engineered peptides

(2010) Dmitriy Khatayevich et al.   Acta Biomaterialia

Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

(2010) Margaret L. Gardel et al.   Annual Review of Cell and Developmental Biology

Effects of immobilizing sites of RGD peptides in amphiphilic block copolymers on efficacy of cell adhesion

(2010) Zheng Zhang et al.   BIOMATERIALS

Cell Adhesion Strength Is Controlled by Intermolecular Spacing of Adhesion Receptors

(2010) C. Selhuber-Unkel et al.   BIOPHYSICAL JOURNAL

Decellularized matrices for tissue engineering

(2010) Takashi Hoshiba et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Surface hydration: Principles and applications toward low-fouling/nonfouling biomaterials

(2010) Shenfu Chen et al.   POLYMER

Multivalent Integrin-Specific Ligands Enhance Tissue Healing and Biomaterial Integration

(2010) T. A. Petrie et al.   Science Translational Medicine

Nanostructured interfaces with RGD arrays to control cell–matrix interaction

(2010) Jinghuan Huang et al.   Soft Matter

Integrins and Extracellular Matrix in Mechanotransduction

(2010) M. A. Schwartz   Cold Spring Harbor Perspectives in Biology

Nanoscale presentation of cell adhesive molecules via block copolymer self-assembly

(2009) Peter A. George et al.   BIOMATERIALS

Self-assembling polystyrene-block-poly(ethylene oxide) copolymer surface coatings: Resistance to protein and cell adhesion

(2009) Peter A. George et al.   BIOMATERIALS

Genetic and cell biological analysis of integrin outside-in signaling

(2009) K. R. Legate et al.   GENES & DEVELOPMENT

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

Fabrication of nanoscale bioarrays for the study of cytoskeletal protein binding interactions using nanoimprint lithography

(2009) M. Schvartzman et al.   JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B

Impact of Order and Disorder in RGD Nanopatterns on Cell Adhesion

(2009) Jinghuan Huang et al.   NANO LETTERS

Assessment of the In Vivo Toxicity of Gold Nanoparticles

(2009) Yu-Shiun Chen et al.   Nanoscale Research Letters

Selective endothelial cell attachment to peptide-modified terpolymers

(2008) Anka N. Veleva et al.   BIOMATERIALS

Cooperativity in Adhesion Cluster Formation during Initial Cell Adhesion

(2008) Christine Selhuber-Unkel et al.   BIOPHYSICAL JOURNAL

Cell adhesion and polarisation on molecularly defined spacing gradient surfaces of cyclic RGDfK peptide patches

(2008) V HIRSCHFELDWARNEKEN et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Kinetically constrained block copolymer self-assembly a simple method to control domain size

(2008) Peter A. George et al.   EUROPEAN POLYMER JOURNAL

Quantifying the relation between bond number and myoblast proliferation

(2008) Tanyarut Boontheekul et al.   FARADAY DISCUSSIONS

Talin at a glance

(2008) D. R. Critchley et al.   JOURNAL OF CELL SCIENCE

Induction of Cell Polarization and Migration by a Gradient of Nanoscale Variations in Adhesive Ligand Spacing

(2008) Marco Arnold et al.   NANO LETTERS

Self-assembling multimeric integrin  5 1 ligands for cell attachment and spreading

(2008) M. Kreiner et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Cell interactions with hierarchically structured nano-patterned adhesive surfaces

(2008) Marco Arnold et al.   Soft Matter

Differentiation stage alters matrix control of stem cells

(2007) Susan X. Hsiong et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A