Manipulation of Mitophagy by “All-in-One” nanosensitizer augments sonodynamic glioma therapy

High-glucose induces retinal pigment epithelium mitochondrial pathways of apoptosis and inhibits mitophagy by regulating ROS/PINK1/Parkin signal pathway

(2019) Yuanping Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Nanoenzyme-Augmented Cancer Sonodynamic Therapy by Catalytic Tumor Oxygenation

(2018) Piao Zhu et al.   ACS Nano

Dual-targeting immunoliposomes using angiopep-2 and CD133 antibody for glioblastoma stem cells

(2018) Jung Seok Kim et al.   JOURNAL OF CONTROLLED RELEASE

Monitoring the Opening and Recovery of the Blood–Brain Barrier with Noninvasive Molecular Imaging by Biodegradable Ultrasmall Cu2–xSe Nanoparticles

(2018) Hao Zhang et al.   NANO LETTERS

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence

(2018) Laura Vera-Ramirez et al.   Nature Communications

Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

(2018) Nir Lipsman et al.   Nature Communications

Listening in on the Microbubble Crowd: Advanced Acoustic Monitoring for Improved Control of Blood-Brain Barrier Opening with Focused Ultrasound

(2018) Catherine M. Gorick et al.   Theranostics

PINK1/Parkin-Mediated Mitophagy Promotes Resistance to Sonodynamic Therapy

(2018) Lin Song et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Enhanced drug delivery using sonoactivatable liposomes with membrane-embedded porphyrins

(2018) Xiaobing Wang et al.   JOURNAL OF CONTROLLED RELEASE

Primary brain tumours in adults

(2018) Sarah Lapointe et al.   LANCET

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

(2018) Konstantinos Palikaras et al.   NATURE CELL BIOLOGY

Inhibition of autophagy promoted high glucose/ROS-mediated apoptosis in ADSCs

(2018) Qiang Li et al.   Stem Cell Research & Therapy

Reactive oxygen species trigger Parkin/PINK1 pathway–dependent mitophagy by inducing mitochondrial recruitment of Parkin

(2017) Bin Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glioma targeted delivery strategy of doxorubicin-loaded liposomes by dual-ligand modification

(2017) Wei Han et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Ultrasound-triggered release of sinoporphyrin sodium from liposome-microbubble complexes and its enhanced sonodynamic toxicity in breast cancer

(2017) Yixiang Li et al.   Nano Research

Ultrasound for the brain

(2017)   NATURE

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

(2017) Jingwei Xue et al.   Nature Nanotechnology

Combination of sonodynamic with temozolomide inhibits C6 glioma migration and promotes mitochondrial pathway apoptosis via suppressing NHE-1 expression

(2017) Lei Chen et al.   ULTRASONICS SONOCHEMISTRY

Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria

(2017) Bin Xiao et al.   Cell Death & Disease

Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

(2017) Farhan Basit et al.   Cell Death & Disease

Blood-brain barrier disruption induced by diagnostic ultrasound combined with microbubbles in mice

(2017) Bingxia Zhao et al.   Oncotarget

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

(2016) Tingting Lin et al.   ACS Nano

Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin

(2016) Yang Wang et al.   Autophagy

Preparation of Angiopep-2 Peptide-Modified Bubble Liposomes for Delivery to the Brain

(2016) Yoko Endo-Takahashi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells

(2016) Sonam Dolma et al.   CANCER CELL

Inhibition of autophagy with chloroquine potentiates carfilzomib-induced apoptosis in myeloma cells in vitro and in vivo

(2016) Vidal Jarauta et al.   CANCER LETTERS

Focused ultrasound-mediated sonochemical internalization: an alternative to light-based therapies

(2016) Jonathan Gonzales et al.   JOURNAL OF BIOMEDICAL OPTICS

Sinoporphyrin sodium triggered sono-photodynamic effects on breast cancer both in vitro and in vivo

(2016) Yichen Liu et al.   ULTRASONICS SONOCHEMISTRY

Non-invasive Measurement of Thermal Diffusivity Using High-Intensity Focused Ultrasound and Through-Transmission Ultrasonic Imaging

(2016) Lilach Yeshurun et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Hypoxia Activation of Mitophagy and Its Role in Disease Pathogenesis

(2015) Hao Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission

(2015) Jing Zhou et al.   Autophagy

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

(2015) Lulu Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Targeted inhibition of p38MAPK-enhanced autophagy in SW620 cells resistant to photodynamic therapy-induced apoptosis

(2015) Qin Xue et al.   LASERS IN MEDICAL SCIENCE

Cell type-dependent ROS and mitophagy response leads to apoptosis or necroptosis in neuroblastoma

(2015) F Radogna et al.   ONCOGENE

Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer

(2014) K. L. Cook et al.   CLINICAL CANCER RESEARCH

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

(2014) Andrea Viale et al.   NATURE

In vitro stimulation of calcium overload and apoptosis by sonodynamic therapy combined with hematoporphyrin monomethyl ether in C6 glioma cells

(2014) SHAOCHUN DAI et al.   Oncology Letters

A smart and versatile theranostic nanomedicine platform based on nanoporphyrin

(2014) Yuanpei Li et al.   Nature Communications

Porphyrin–phospholipid liposomes permeabilized by near-infrared light

(2014) Kevin A. Carter et al.   Nature Communications

Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain Tumors

(2014) J. M. M. Levy et al.   Cancer Discovery

Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma

(2013) J Shen et al.   BRITISH JOURNAL OF CANCER

Influence of Nanoparticle Shape, Size, and Surface Functionalization on Cellular Uptake

(2013) Ningning Ma et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy

(2012) Yuqing Wang et al.   Autophagy

Cage the firefly luciferin! – a strategy for developing bioluminescent probes

(2012) Jing Li et al.   CHEMICAL SOCIETY REVIEWS

Initiation of autophagy and apoptosis by sonodynamic therapy in murine leukemia L1210 cells

(2012) Xiaobing Wang et al.   TOXICOLOGY IN VITRO

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

Autophagosome Precursor Maturation Requires Homotypic Fusion

(2011) Kevin Moreau et al.   CELL

Mitophagy Selectively Degrades Individual Damaged Mitochondria After Photoirradiation

(2010) Insil Kim et al.   ANTIOXIDANTS & REDOX SIGNALING

ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy

(2010) Michael Dewaele et al.   Autophagy

Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain

(2010) Inge van Rooy et al.   JOURNAL OF CONTROLLED RELEASE

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

Sonodynamically induced anti-tumor effect with protoporphyrin IX on hepatoma-22 solid tumor

(2010) Xiaobing Wang et al.   ULTRASONICS

Role of Autophagy in Sonodynamic Therapy-Induced Cytotoxicity in S180 Cells

(2010) Xiaobing Wang et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Blocked Autophagy Sensitizes Resistant Carcinoma Cells to Radiation Therapy

(2008) A. Apel et al.   CANCER RESEARCH