Drug Transport across the Blood–Brain Barrier

Imaging Amyloid Plaque in Alzheimer’s Disease Brain with a Biotinylated Aβ Peptide Radiopharmaceutical Conjugated to an IgG-Avidin Fusion Protein

(2012) Rachita K. Sumbria et al.   BIOCONJUGATE CHEMISTRY

Delivery of a Peptide Radiopharmaceutical to Brain with an IgG-Avidin Fusion Protein

(2011) Qing-Hui Zhou et al.   BIOCONJUGATE CHEMISTRY

Novel18F-Labeled Benzofuran Derivatives with Improved Properties for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques in Alzheimer’s Brains

(2011) Masahiro Ono et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Developmental Aspects of the Intracerebral Microvasculature and Perivascular Spaces: Insights into Brain Response to Late-Life Diseases

(2011) Miguel Marín-Padilla et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Quantitative Targeted Absolute Proteomics-Based Adme Research as A New Path to Drug Discovery and Development: Methodology, Advantages, Strategy, and Prospects

(2011) Sumio Ohtsuki et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Proton-driven sucrose symport and antiport are provided by the vacuolar transporters SUC4 and TMT1/2

(2011) Alexander Schulz et al.   PLANT JOURNAL

Monoclonal Antibody-Glial-Derived Neurotrophic Factor Fusion Protein Penetrates the Blood-Brain Barrier in the Mouse

(2010) Q.-H. Zhou et al.   DRUG METABOLISM AND DISPOSITION

Pattern of P450 expression at the human blood-brain barrier: Roles of epileptic condition and laminar flow

(2010) Chaitali Ghosh et al.   EPILEPSIA

Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein

(2010) Ruben J. Boado et al.   JOURNAL OF BIOTECHNOLOGY

Biopharmaceutical drug targeting to the brain

(2010) William M. Pardridge   JOURNAL OF DRUG TARGETING

New Angiopep-Modified Doxorubicin (ANG1007) and Etoposide (ANG1009) Chemotherapeutics With Increased Brain Penetration

(2010) Christian Ché et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rapid, Reversible Modulation of Blood-Brain BarrierP-Glycoprotein Transport Activity by Vascular Endothelial Growth Factor

(2010) B. T. Hawkins et al.   JOURNAL OF NEUROSCIENCE

Drug Targeting of Erythropoietin Across the Primate Blood-Brain Barrier with an IgG Molecular Trojan Horse

(2010) R. J. Boado et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Blood-Brain Barrier: Geriatric Relevance of a Critical Brain-Body Interface

(2010) Neer Zeevi et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

The Pharmacokinetics of Cell-Penetrating Peptides

(2010) Dikran Sarko et al.   MOLECULAR PHARMACEUTICS

Comparison of Blood-Brain Barrier Transport of Glial-Derived Neurotrophic Factor (GDNF) and an IgG-GDNF Fusion Protein in the Rhesus Monkey

(2009) R. J. Boado et al.   DRUG METABOLISM AND DISPOSITION

Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells

(2008) Sandrine Dauchy et al.   BIOCHEMICAL PHARMACOLOGY

Genetic Engineering, Expression, and Activity of a Chimeric Monoclonal Antibody−Avidin Fusion Protein for Receptor-Mediated Delivery of Biotinylated Drugs in Humans

(2008) Ruben J. Boado et al.   BIOCONJUGATE CHEMISTRY

Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse

(2008) Ruben J. Boado et al.   BIOTECHNOLOGY AND BIOENGINEERING

LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model

(2008) Babak Nazer et al.   NEUROBIOLOGY OF DISEASE

The distribution of D2/D3 receptor binding in the adolescent rhesus monkey using small animal PET imaging

(2008) B CHRISTIAN et al.   NEUROIMAGE

A Unique Carrier for Delivery of Therapeutic Compounds beyond the Blood-Brain Barrier

(2008) Delara Karkan et al.   PLoS One