Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways
出版年份 2020 全文链接
标题
Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways
作者
关键词
-
出版物
Nature Communications
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-01-30
DOI
10.1038/s41467-019-14036-x
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma
- (2019) Xiangqi Meng et al. EBioMedicine
- Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy
- (2019) Lei Han et al. ADVANCED MATERIALS
- Lnc-TALC promotes O6-methylguanine-DNA methyltransferase expression via regulating the c-Met pathway by competitively binding with miR-20b-3p
- (2019) Pengfei Wu et al. Nature Communications
- Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma
- (2018) Bo Han et al. CANCER LETTERS
- Peptide-Functionalized Nanoinhibitor Restrains Brain Tumor Growth by Abrogating Mesenchymal-Epithelial Transition Factor (MET) Signaling
- (2018) Yingwei Wu et al. NANO LETTERS
- Immunotherapy offers a promising bet against brain cancer
- (2018) Michael Eisenstein NATURE
- Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor
- (2018) Huimin Hu et al. CELL
- Nanocomposites Inhibit the Formation, Mitigate the Neurotoxicity, and Facilitate the Removal of β-Amyloid Aggregates in Alzheimer’s Disease Mice
- (2018) Yu Zhao et al. NANO LETTERS
- Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures
- (2017) Faiz M. Khan et al. Nature Communications
- Mustard-inspired delivery shuttle for enhanced blood–brain barrier penetration and effective drug delivery in glioma therapy
- (2017) Nan Wang et al. Biomaterials Science
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- CGCG clinical practice guidelines for the management of adult diffuse gliomas
- (2016) Tao Jiang et al. CANCER LETTERS
- Recent progress in protein-protein interaction study for EGFR-targeted therapeutics
- (2016) Rebecca Christine Feiner et al. Expert Review of Proteomics
- A novel antagonist anti-cMet antibody with antitumor activities targeting both ligand-dependent and ligand-independent c-Met receptors
- (2016) Alexandra Gonzalez et al. INTERNATIONAL JOURNAL OF CANCER
- c-Met–mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma
- (2016) Menggui Huang et al. JOURNAL OF CLINICAL INVESTIGATION
- Classification based on mutations ofTERTpromoter andIDHcharacterizes subtypes in grade II/III gliomas
- (2016) Pei Yang et al. NEURO-ONCOLOGY
- Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers
- (2016) Erik S. Linklater et al. Oncotarget
- Low c-Met expression levels are prognostic for and predict the benefits of temozolomide chemotherapy in malignant gliomas
- (2016) Ming-Yang Li et al. Scientific Reports
- Hallmarks of cancer and AU-rich elements
- (2016) Khalid S. A. Khabar Wiley Interdisciplinary Reviews-RNA
- Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma
- (2015) Lu Dai et al. BLOOD
- Spatiotemporal Evolution of the Primary Glioblastoma Genome
- (2015) Jinkuk Kim et al. CANCER CELL
- E2F1 and E2F2 induction in response to DNA damage preserves genomic stability in neuronal cells
- (2015) Daniela S Castillo et al. CELL CYCLE
- Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response
- (2015) Hong-Jen Lee et al. CELL RESEARCH
- Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met
- (2015) Jacobus Burggraaf et al. NATURE MEDICINE
- Nuclear factor-κB in glioblastoma: insights into regulators and targeted therapy
- (2015) Kirk E. Cahill et al. NEURO-ONCOLOGY
- Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas
- (2015) NEW ENGLAND JOURNAL OF MEDICINE
- Opportunities and challenges provided by crosstalk between signalling pathways in cancer
- (2015) A Prahallad et al. ONCOGENE
- The Blood–Brain Barrier
- (2015) Richard Daneman et al. Cold Spring Harbor Perspectives in Biology
- Targeting RTK Signaling Pathways in Cancer
- (2015) Tarik Regad Cancers
- RRAD Promotes EGFR-Mediated STAT3 Activation and Induces Temozolomide Resistance of Malignant Glioblastoma
- (2014) S.-Y. Yeom et al. MOLECULAR CANCER THERAPEUTICS
- Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43
- (2014) J L Munoz et al. Cell Death & Disease
- Distinguishing Score 0 From Score 1+ in HER2 Immunohistochemistry-Negative Breast Cancer
- (2013) Kathleen Lambein et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action
- (2013) Seth A. Brooks et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- EGFR and EGFRvIII in Glioblastoma: Partners in Crime
- (2013) Gelareh Zadeh et al. CANCER CELL
- p38 MAPK/PP2Acα/TTP pathway on the connection of TNF-α and caspases activation on hydroquinone-induced apoptosis
- (2013) Wen-Hsin Liu et al. CARCINOGENESIS
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- A Peptide Antagonist of ErbB Receptors, Inherbin3, Induces Neurite Outgrowth from Rat Cerebellar Granule Neurons Through ErbB1 Inhibition
- (2013) Ruodan Xu et al. NEUROCHEMICAL RESEARCH
- Development of an Epidermal Growth Factor Derivative with EGFR Blocking Activity
- (2013) Clara Panosa et al. PLoS One
- Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent
- (2013) M. Merchant et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell-Autonomous and Non-Cell-Autonomous Mechanisms of HGF/MET-Driven Resistance to Targeted Therapies: From Basic Research to a Clinical Perspective
- (2013) S. Corso et al. Cancer Discovery
- Peptides as Targeting Elements and Tissue Penetration Devices for Nanoparticles
- (2012) Erkki Ruoslahti ADVANCED MATERIALS
- STAT3 Inhibition Overcomes Temozolomide Resistance in Glioblastoma by Downregulating MGMT Expression
- (2012) Shinji Kohsaka et al. MOLECULAR CANCER THERAPEUTICS
- Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress
- (2012) Andrea R Tentner et al. Molecular Systems Biology
- Overcoming Temozolomide Resistance in Glioblastoma via Dual Inhibition of NAD+ Biosynthesis and Base Excision Repair
- (2011) E. M. Goellner et al. CANCER RESEARCH
- Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells
- (2011) Y.-C. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- Receptor Tyrosine Kinase Coactivation Networks in Cancer
- (2010) A. M. Xu et al. CANCER RESEARCH
- HGF Rescues Colorectal Cancer Cells from EGFR Inhibition via MET Activation
- (2010) D. Liska et al. CLINICAL CANCER RESEARCH
- The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
- (2010) Ankur Sharma et al. JOURNAL OF CLINICAL INVESTIGATION
- Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034
- (2009) Martin J. van den Bent et al. JOURNAL OF CLINICAL ONCOLOGY
- Characterization, biodistribution and small-animal SPECT of I-125-labeled c-Met binding peptide in mice bearing c-Met receptor tyrosine kinase-positive tumor xenografts
- (2009) Eun-Mi Kim et al. NUCLEAR MEDICINE AND BIOLOGY
- Constitutively Activated STAT3 Frequently Coexpresses with Epidermal Growth Factor Receptor in High-Grade Gliomas and Targeting STAT3 Sensitizes Them to Iressa and Alkylators
- (2008) H.-W. Lo et al. CLINICAL CANCER RESEARCH
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK
- (2008) K. A. Boehme et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started