标题
Chemical Evolution of Natural Product Structure
作者
关键词
-
出版物
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume -, Issue -, Pages -
出版商
American Chemical Society (ACS)
发表日期
2022-02-22
DOI
10.1021/jacs.1c11270
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Natural Product Synthesis through the Lens of Informatics
- (2021) Stone Woo et al. ACCOUNTS OF CHEMICAL RESEARCH
- Pseudo Natural Products ‐ Chemical Evolution of Natural Product Structure
- (2021) Herbert Waldmann et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Decade of FDA-Approved Drugs (2010–2019): Trends and Future Directions
- (2021) Dean G. Brown et al. JOURNAL OF MEDICINAL CHEMISTRY
- Natural products in drug discovery: advances and opportunities
- (2021) Atanas G. Atanasov et al. NATURE REVIEWS DRUG DISCOVERY
- Trends in Hit-to-Lead Optimization Following DNA-Encoded Library Screens
- (2021) Christopher A. Reiher et al. ACS Medicinal Chemistry Letters
- Recent Advances on the Selection Methods of DNA‐Encoded Libraries
- (2021) Yiran Huang et al. CHEMBIOCHEM
- Natural product fragment combination to performance-diverse pseudo-natural products
- (2021) Michael Grigalunas et al. Nature Communications
- Combination of Pseudo‐Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo‐Sesquiterpenoid Alkaloids
- (2021) Jie Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Identification of isoform/domain-selective fragments from the selection of DNA-encoded dynamic library
- (2021) Yu Zhou et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Magic Rings: Navigation in the Ring Chemical Space Guided by the Bioactive Rings
- (2021) Peter Ertl Journal of Chemical Information and Modeling
- Synthesis of Indofulvin Pseudo‐Natural Products Yields a New Autophagy Inhibitor Chemotype
- (2021) Annina Burhop et al. Advanced Science
- Identification of Inhibitors of Cholesterol Transport Proteins Through the Synthesis of a Diverse, Sterol‐Inspired Compound Collection
- (2021) Thomas Whitmarsh‐Everiss et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Privileged Biorenewable Secologanin‐Based Diversity‐Oriented Synthesis for Pseudo‐Natural Alkaloids: Uncovering Novel Neuroprotective and Antimalarial Frameworks
- (2021) Huajian Zhu et al. ChemSusChem
- Pseudonatural Products Occur Frequently in Biologically Relevant Compounds
- (2021) José-Manuel Gally et al. Journal of Chemical Information and Modeling
- Principle and design of pseudo-natural products
- (2020) George Karageorgis et al. Nature Chemistry
- Pseudo-natural products and natural product-inspired methods in chemical biology and drug discovery
- (2020) Michael Grigalunas et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
- (2020) David J. Newman et al. JOURNAL OF NATURAL PRODUCTS
- Chemoreactive-Inspired Discovery of Influenza A Virus Dual Inhibitor to Block Hemagglutinin-Mediated Adsorption and Membrane Fusion
- (2020) Guangwei Wu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cheminformatics in Natural Product‐Based Drug Discovery
- (2020) Ya Chen et al. Molecular Informatics
- Synthetic, Mechanistic, and Biological Interrogation of Ginkgo biloba Chemical Space En Route to (−)-Bilobalide
- (2020) Robert M. Demoret et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products
- (2020) Jie Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Natural Products in the “Marketplace”: Interfacing Synthesis and Biology
- (2019) Benjamin J. Huffman et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- DNA Barcoding a Complete Matrix of Stereoisomeric Small Molecules
- (2019) Christopher J. Gerry et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The symbiotic relationship between drug discovery and organic chemistry
- (2019) Oleksandr O Grygorenko et al. CHEMISTRY-A EUROPEAN JOURNAL
- Synthesis of Indomorphan Pseudo-Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3
- (2019) Javier Ceballos et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Genome Mining of Alkaloidal Terpenoids from a Hybrid Terpene and Nonribosomal Peptide Biosynthetic Pathway
- (2019) Danielle A. Yee et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent achievements and current trajectories of diversity-oriented synthesis
- (2019) Christopher J Gerry et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead
- (2018) Emanuela Martino et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Characterization of the Chemical Space of Known and Readily Obtainable Natural Products
- (2018) Ya Chen et al. Journal of Chemical Information and Modeling
- Three previously unrecognised classes of biosynthetic enzymes revealed during the production of xenovulene A
- (2018) Raissa Schor et al. Nature Communications
- Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry
- (2018) Hoan Vu et al. ACS Infectious Diseases
- Protein–protein interactions in polyketide synthase–nonribosomal peptide synthetase hybrid assembly lines
- (2018) Akimasa Miyanaga et al. NATURAL PRODUCT REPORTS
- Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3
- (2018) George Karageorgis et al. Nature Chemistry
- Nature Inspired Small Molecules for Chemical Biology
- (2018) Kamal Kumar et al. ISRAEL JOURNAL OF CHEMISTRY
- Chemical Space and Diversity of the NuBBE Database: A Chemoinformatic Characterization
- (2018) Fernanda I. Saldívar-González et al. Journal of Chemical Information and Modeling
- DNA-Encoded Dynamic Chemical Library and Its Applications in Ligand Discovery
- (2018) Yu Zhou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Guided by Evolution: Biology-Oriented Synthesis of Bioactive Compound Classes
- (2018) Herbert Waldmann et al. SYNTHESIS-STUTTGART
- Retrospective analysis of natural products provides insights for future discovery trends
- (2017) Cameron R. Pye et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis
- (2016) Erika A. Crane et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hybrid molecules: The privileged scaffolds for various pharmaceuticals
- (2016) Shaveta et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- An Additive Definition of Molecular Complexity
- (2016) Thomas Böttcher Journal of Chemical Information and Modeling
- Chemical Space of DNA-Encoded Libraries
- (2016) Raphael M. Franzini et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes
- (2016) Mark-Anthony Bray et al. Nature Protocols
- Enzymatic Basis of “Hybridity” in Thiomarinol Biosynthesis
- (2015) Zachary D. Dunn et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Theoretical insight into the structural mechanism for the binding of vinblastine with tubulin
- (2015) Shaoming Chi et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Capturing Nature's Diversity
- (2015) Mauro Pascolutti et al. PLoS One
- Kinetically controlled phenomena in dynamic combinatorial libraries
- (2014) Qing Ji et al. CHEMICAL SOCIETY REVIEWS
- Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids
- (2014) Kunal Nepali et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Rings in Drugs
- (2014) Richard D. Taylor et al. JOURNAL OF MEDICINAL CHEMISTRY
- Biology-Oriented Synthesis: Harnessing the Power of Evolution
- (2014) Hilde van Hattum et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis
- (2014) Joshua K Salabei et al. Nature Protocols
- Yeast Synthetic Biology Platform Generates Novel Chemical Structures as Scaffolds for Drug Discovery
- (2014) Jens Klein et al. ACS Synthetic Biology
- Synthesis of Complex and Diverse Compounds through Ring Distortion of Abietic Acid
- (2013) Ryan J. Rafferty et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Natural products as starting points for the synthesis of complex and diverse compounds
- (2013) Karen C. Morrison et al. NATURAL PRODUCT REPORTS
- A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products
- (2013) Robert W. Huigens III et al. Nature Chemistry
- Structure of the δ-opioid receptor bound to naltrindole
- (2012) Sébastien Granier et al. NATURE
- Natural-product-derived fragments for fragment-based ligand discovery
- (2012) Björn Over et al. Nature Chemistry
- Escape from Flatland 2: complexity and promiscuity
- (2012) Frank Lovering MedChemComm
- Biology-Oriented Synthesis
- (2011) Stefan Wetzel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hybrid Molecules Incorporating Natural Products: Applications in Cancer Therapy, Neurodegenerative Disorders and Beyond
- (2011) M. Decker CURRENT MEDICINAL CHEMISTRY
- A Small Nonrule of 3 Compatible Fragment Library Provides High Hit Rate of Endothiapepsin Crystal Structures with Various Fragment Chemotypes
- (2011) Helene Köster et al. JOURNAL OF MEDICINAL CHEMISTRY
- Natural product–inspired cascade synthesis yields modulators of centrosome integrity
- (2011) Heiko Dückert et al. Nature Chemical Biology
- Bioactivity-Guided Navigation of Chemical Space
- (2010) Robin S. Bon et al. ACCOUNTS OF CHEMICAL RESEARCH
- Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
- (2009) Frank Lovering et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular diversity by design
- (2009) Stuart L. Schreiber NATURE
- Function-Oriented Synthesis, Step Economy, and Drug Design
- (2007) Paul A. Wender et al. ACCOUNTS OF CHEMICAL RESEARCH
- Natural Product-likeness Score and Its Application for Prioritization of Compound Libraries
- (2007) Peter Ertl et al. Journal of Chemical Information and Modeling
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