The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation

Latent TGF-β Activation Is a Hallmark of the Tenascin Family

(2021) Alexandre Aubert et al.   Frontiers in Immunology

The Combined Influence of Viscoelastic and Adhesive Cues on Fibroblast Spreading and Focal Adhesion Organization

(2021) Erica Hui et al.   Cellular and Molecular Bioengineering

Integrated spatial multiomics reveals fibroblast fate during tissue repair

(2021) Deshka S. Foster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of thrombospondin-4 on pro-inflammatory phenotype differentiation and apoptosis in macrophages

(2020) Mohammed Tanjimur Rahman et al.   Cell Death & Disease

Spatial-omics: Novel Approaches to Probe Cell Heterogeneity and Extracellular Matrix Biology

(2020) Grace C. Bingham et al.   MATRIX BIOLOGY

Mapping the epigenetic modifications of DNA and RNA

(2020) Lin-Yong Zhao et al.   Protein & Cell

BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1

(2020) Cyril Anastasi et al.   Science Signaling

Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

(2020) Arun C. Habermann et al.   Science Advances

Single-cell multiomics: technologies and data analysis methods

(2020) Jeongwoo Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

The hallmarks of cancer are also the hallmarks of wound healing

(2020) Lucy MacCarthy-Morrogh et al.   Science Signaling

Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration

(2020) Karis Little et al.   Journal of Neuroinflammation

Inflammation and Immunity in IPF Pathogenesis and Treatment

(2019) P. Heukels et al.   RESPIRATORY MEDICINE

Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β

(2019) Monika Lodyga et al.   Science Signaling

Defining the Activated Fibroblast Population in Lung Fibrosis Using Single Cell Sequencing

(2019) Rebecca Peyser et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasion

(2019) Victoria L. Stefanelli et al.   MATRIX BIOLOGY

Distinct fibroblast subsets drive inflammation and damage in arthritis

(2019) Adam P. Croft et al.   NATURE

Dynamic fibroblast contractions attract remote macrophages in fibrillar collagen matrix

(2019) Pardis Pakshir et al.   Nature Communications

IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways

(2019) Martijn L. Manson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Integrins in wound healing, fibrosis and tumor stroma: High potential targets for therapeutics and drug delivery

(2018) Jonas Schnittert et al.   ADVANCED DRUG DELIVERY REVIEWS

Inhibiting Fibronectin Attenuates Fibrosis and Improves Cardiac Function in a Model of Heart Failure

(2018) Iñigo Valiente-Alandi et al.   CIRCULATION

Genetically-modified bone mesenchymal stem cells with TGF-β 3 improve wound healing and reduce scar tissue formation in a rabbit model

(2018) Mingyong Li et al.   EXPERIMENTAL CELL RESEARCH

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

(2018) Charles L. Evavold et al.   IMMUNITY

Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations

(2018) Christina Philippeos et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease

(2018) Joanne E. Murphy-Ullrich et al.   MATRIX BIOLOGY

More than a syllable in fib-ROS-is: The role of ROS on the fibrotic extracellular matrix and on cellular contacts

(2018) Julius Grosche et al.   MOLECULAR ASPECTS OF MEDICINE

Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice

(2018) Delphine Gomez et al.   NATURE MEDICINE

A microengineered vascularized bleeding model that integrates the principal components of hemostasis

(2018) Yumiko Sakurai et al.   Nature Communications

Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis

(2018) Ting Xie et al.   Cell Reports

TGF-β receptors: In and beyond TGF-β signaling

(2018) Alexandra Vander Ark et al.   CELLULAR SIGNALLING

LEM domain–containing protein 3 antagonizes TGFβ-SMAD2/3 signaling in a stiffness-dependent manner in both the nucleus and cytosol

(2018) Dwight M. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A positive feedback loop bi-stably activates fibroblasts

(2018) So-Young Yeo et al.   Nature Communications

FSP1-positive fibroblasts are adipogenic niche and regulate adipose homeostasis

(2018) Rui Zhang et al.   PLOS BIOLOGY

Pdgfra marks a cellular lineage with distinct contributions to myofibroblasts in lung maturation and injury response

(2018) Rongbo Li et al.   eLife

Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force

(2018) Kalpana Mandal et al.   ACS Nano

Tenascin-C accelerates adverse ventricular remodelling after myocardial infarction by modulating macrophage polarization

(2018) Taizo Kimura et al.   CARDIOVASCULAR RESEARCH

Unique behavior of dermal cells from regenerative mammal, the African Spiny Mouse, in response to substrate stiffness

(2018) Daniel C. Stewart et al.   JOURNAL OF BIOMECHANICS

The innate immune receptor TREM-1 promotes liver injury and fibrosis

(2018) Anh Thu Nguyen-Lefebvre et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-33 encourages scar formation in murine fetal skin wounds

(2018) Brian C. Wulff et al.   WOUND REPAIR AND REGENERATION

Interleukin-10–mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling

(2017) Swathi Balaji et al.   FASEB JOURNAL

Hepatocyte Growth Factor Mediates Enhanced Wound Healing Responses and Resistance to Transforming Growth Factor-β1-Driven Myofibroblast Differentiation in Oral Mucosal Fibroblasts

(2017) Jordanna Dally et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipopolysaccharide/TLR4 Stimulates IL-13 Production through a MyD88-BLT2–Linked Cascade in Mast Cells, Potentially Contributing to the Allergic Response

(2017) A-Jin Lee et al.   JOURNAL OF IMMUNOLOGY

Macrophage-Mediated Inflammation in Normal and Diabetic Wound Healing

(2017) Anna E. Boniakowski et al.   JOURNAL OF IMMUNOLOGY

TGF-β1 Suppresses IL-33–Induced Mast Cell Function

(2017) Victor S. Ndaw et al.   JOURNAL OF IMMUNOLOGY

Personalized plasma-based medicine to treat age-related diseases

(2017) Eduardo Anitua et al.   Materials Science & Engineering C-Materials for Biological Applications

The provisional matrix: setting the stage for tissue repair outcomes

(2017) Thomas H. Barker et al.   MATRIX BIOLOGY

Fibrin mechanical properties and their structural origins

(2017) Rustem I. Litvinov et al.   MATRIX BIOLOGY

Heparin, Heparan Sulphate and the TGF-β Cytokine Superfamily

(2017) et al.   MOLECULES

Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2

(2017) Naomi McGovern et al.   NATURE

TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives

(2017) Alessandra Tammaro et al.   PHARMACOLOGY & THERAPEUTICS

A hypoxia response element in the Vegfa promoter is required for basal Vegfa expression in skin and for optimal granulation tissue formation during wound healing in mice

(2017) Domenic Ciarlillo et al.   PLoS One

Inflammation and metabolism in tissue repair and regeneration

(2017) Sabine A. Eming et al.   SCIENCE

Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice

(2017) Nadine Lohmann et al.   Science Translational Medicine

The Scaffold Immune Microenvironment: Biomaterial-Mediated Immune Polarization in Traumatic and Nontraumatic Applications

(2017) Kaitlyn Sadtler et al.   TISSUE ENGINEERING PART A

αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin

(2017) Mitasha Bharadwaj et al.   Nature Communications

Matrix-regulated integrin αvβ5 maintains α5β1-dependent desmoplastic traits prognostic of neoplastic recurrence

(2017) Janusz Franco-Barraza et al.   eLife

Fibroblasts: Diverse Cells Critical to Biomaterials Integration

(2017) Riley T. Hannan et al.   ACS Biomaterials-Science & Engineering

The role of α9β1 integrin and its ligands in the development of autoimmune diseases

(2017) Shigeyuki Kon et al.   Journal of Cell Communication and Signaling

Fibroblasts: Diverse Cells Critical to Biomaterials Integration

(2017) Riley T. Hannan et al.   ACS Biomaterials Science & Engineering

α-Smooth muscle actin is an inconsistent marker of fibroblasts responsible for force-dependent TGFβ activation or collagen production across multiple models of organ fibrosis

(2016) Kai-Hui Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Fibrin Network Changes in Neonates after Cardiopulmonary Bypass

(2016) Ashley C. Brown et al.   ANESTHESIOLOGY

A Reservoir of Mature Cavity Macrophages that Can Rapidly Invade Visceral Organs to Affect Tissue Repair

(2016) Jing Wang et al.   CELL

Editorial: Wound healing and fibrosis—two sides of the same coin

(2016) Donald Gullberg et al.   CELL AND TISSUE RESEARCH

Scarless wound healing: finding the right cells and signals

(2016) Tripp Leavitt et al.   CELL AND TISSUE RESEARCH

IL-17A promotes neutrophilic inflammation and disturbs acute wound healing in skin

(2016) Naoyuki Takagi et al.   EXPERIMENTAL DERMATOLOGY

Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation

(2016) Janine Woytschak et al.   IMMUNITY

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

The integrin–collagen connection – a glue for tissue repair?

(2016) Cédric Zeltz et al.   JOURNAL OF CELL SCIENCE

Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation

(2016) Christian C. Yost et al.   JOURNAL OF CLINICAL INVESTIGATION

Gαi2 and Gαi3 Differentially Regulate Arrest from Flow and Chemotaxis in Mouse Neutrophils

(2016) Yoshihiro Kuwano et al.   JOURNAL OF IMMUNOLOGY

IL-10–Induced miR-155 Targets SOCS1 To Enhance IgE-Mediated Mast Cell Function

(2016) Amina Abdul Qayum et al.   JOURNAL OF IMMUNOLOGY

Lactic Acid Suppresses IL-33–Mediated Mast Cell Inflammatory Responses via Hypoxia-Inducible Factor-1α–Dependent miR-155 Suppression

(2016) Daniel Abebayehu et al.   JOURNAL OF IMMUNOLOGY

Tenascin-C Is a Major Component of the Fibrogenic Niche in Kidney Fibrosis

(2016) Haiyan Fu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis

(2016) Kevin M. Vannella et al.   Science Translational Medicine

Dendritic cells modulate burn wound healing by enhancing early proliferation

(2016) Monika Vinish et al.   WOUND REPAIR AND REGENERATION

Transforming growth factor beta (TGF-β) isoforms in wound healing and fibrosis

(2016) Michael K. Lichtman et al.   WOUND REPAIR AND REGENERATION

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

(2016) Xiao-Ming Meng et al.   Cell Death & Disease

Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis

(2016) Huaping Chen et al.   Nature Communications

Tenascin-C drives persistence of organ fibrosis

(2016) Swati Bhattacharyya et al.   Nature Communications

Molecular interference of fibrin's divalent polymerization mechanism enables modulation of multiscale material properties

(2015) Ashley C. Brown et al.   BIOMATERIALS

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds

(2015) Kara L. Spiller et al.   BIOMATERIALS

Platelet geometry sensing spatially regulates  -granule secretion to enable matrix self-deposition

(2015) Y. Sakurai et al.   BLOOD

Comparative Analysis of the Expression of Surface Markers on Fibroblasts and Fibroblast-Like Cells Isolated from Different Human Tissues

(2015) A. Yu. Lupatov et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Inhibition of Wnt/β-catenin pathway promotes regenerative repair of cutaneous and cartilage injury

(2015) Dikshya Bastakoty et al.   FASEB JOURNAL

The Ectoenzyme E-NPP3 Negatively Regulates ATP-Dependent Chronic Allergic Responses by Basophils and Mast Cells

(2015) Shih Han Tsai et al.   IMMUNITY

Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction

(2015) Vincent F. Fiore et al.   JOURNAL OF CELL BIOLOGY

Transforming growth factor-β (TGF-β) signaling in healthy human fetal skin: A descriptive study

(2015) M. Walraven et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

(2015) Soung-Hoon Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reduced Granulation Tissue and Wound Strength in the Absence of α11β1 Integrin

(2015) Jan-Niklas Schulz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Interferon-Gamma Enhances TLR3 Expression and Anti-Viral Activity in Keratinocytes

(2015) A.i. Kajita et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The α4β1 integrin and the EDA domain of fibronectin regulate a profibrotic phenotype in dermal fibroblasts

(2015) Arti V. Shinde et al.   MATRIX BIOLOGY

The Inflammatory Actions of Coagulant and Fibrinolytic Proteases in Disease

(2015) Michael Schuliga   MEDIATORS OF INFLAMMATION

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

(2015) Siu Ling Wong et al.   NATURE MEDICINE

The α v β 1 integrin plays a critical in vivo role in tissue fibrosis

(2015) Nilgun I. Reed et al.   Science Translational Medicine

BMP signalling: agony and antagony in the family

(2015) Derek P. Brazil et al.   TRENDS IN CELL BIOLOGY

The influence of platelet-derived products on angiogenesis and tissue repair: a concise update

(2015) Constanza E. Martínez et al.   Frontiers in Physiology

Utilizing Fibronectin Integrin-Binding Specificity to Control Cellular Responses

(2015) Haylee Bachman et al.   Advances in Wound Care

The use of antibody modified liposomes loaded with AMO-1 to deliver oligonucleotides to ischemic myocardium for arrhythmia therapy

(2014) Meifang Liu et al.   BIOMATERIALS

S-Glutathionylation of Cryptic Cysteines Enhances Titin Elasticity by Blocking Protein Folding

(2014) Jorge Alegre-Cebollada et al.   CELL

Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice

(2014) Y. Y. Sanders et al.   EUROPEAN RESPIRATORY JOURNAL

Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-β

(2014) Lindsay B. Alcaraz et al.   JOURNAL OF CELL BIOLOGY

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation

(2014) Franco Klingberg et al.   JOURNAL OF CELL BIOLOGY

Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway

(2014) Tao Du et al.   Molecular Cancer

Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation

(2014) Yongzhi Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblasts probe substrate rigidity with filopodia extensions before occupying an area

(2014) Stephanie Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transplantation of Fetal Instead of Adult Fibroblasts Reduces the Probability of Ectopic Ossification During Tendon Repair

(2014) Zhi Fang et al.   TISSUE ENGINEERING PART A

Tenascin-C: Form versus function

(2014) Sean P Giblin et al.   Cell Adhesion & Migration

Incomplete Deletion of IL-4Rα by LysMCre Reveals Distinct Subsets of M2 Macrophages Controlling Inflammation and Fibrosis in Chronic Schistosomiasis

(2014) Kevin M. Vannella et al.   PLoS Pathogens

Towards Scarless Wound Healing: A Comparison of Protein Expression between Human, Adult and Foetal Fibroblasts

(2014) Sonia Ho et al.   Biomed Research International

Gremlin Activates the Smad Pathway Linked to Epithelial Mesenchymal Transdifferentiation in Cultured Tubular Epithelial Cells

(2014) Raquel Rodrigues-Diez et al.   Biomed Research International

TGF-β Activation and Function in Immunity

(2013) Mark A. Travis et al.   Annual Review of Immunology

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

Effect of the GPI anchor of human Thy-1 on antibody recognition and function

(2013) John E Bradley et al.   LABORATORY INVESTIGATION

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

(2013) Neil C Henderson et al.   NATURE MEDICINE

Interleukin Expression after Injury and the Effects of Interleukin-1 Receptor Antagonist

(2013) Connie S. Chamberlain et al.   PLoS One

The alarmin HMGB-1 influences healing outcomes in fetal skin wounds

(2013) Adrienne D. Dardenne et al.   WOUND REPAIR AND REGENERATION

Biomechanics of Scar Tissue and Uninjured Skin

(2013) David T. Corr et al.   Advances in Wound Care

Dynamics of Transforming Growth Factor Beta Signaling in Wound Healing and Scarring

(2013) Kenneth W. Finnson et al.   Advances in Wound Care

The Importance of Mast Cells in Dermal Scarring

(2013) Traci A. Wilgus et al.   Advances in Wound Care

Low α2β1 Integrin Function Enhances the Proliferation of Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis by Activation of the β-Catenin Pathway

(2012) Hong Xia et al.   AMERICAN JOURNAL OF PATHOLOGY

Matrix Stiffness–Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction

(2012) Xiangwei Huang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Regulatory Role of Dendritic Cells in Postinfarction Healing and Left Ventricular Remodeling

(2012) Atsushi Anzai et al.   CIRCULATION

Wound Repair and Regeneration

(2012) J.M. Reinke et al.   EUROPEAN SURGICAL RESEARCH

Extra-domain B in Oncofetal Fibronectin Structurally Promotes Fibrillar Head-to-tail Dimerization of Extracellular Matrix Protein

(2012) André Schiefner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III

(2012) Samir W. Hamaia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Integrin  2 1 Ameliorates Glomerular Injury

(2012) C. M. Borza et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms

(2012) Mariya T. Sweetwyne et al.   MATRIX BIOLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Transforming Growth Factor Beta 3 Is Required for Excisional Wound Repair In Vivo

(2012) Mark Le et al.   PLoS One

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials

(2011) Bryan N. Brown et al.   Acta Biomaterialia

β-catenin signaling

(2011) Anna P. Lam et al.   CURRENT OPINION IN RHEUMATOLOGY

Fibronectin splice variants: Understanding their multiple roles in health and disease using engineered mouse models

(2011) Eric S. White et al.   IUBMB LIFE

Mast Cells Contribute to Scar Formation during Fetal Wound Healing

(2011) Brian C. Wulff et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Unknown

(2011) Carla Jennewein et al.   MOLECULAR MEDICINE

Latent TGF-β structure and activation

(2011) Minlong Shi et al.   NATURE

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY

The Thrombospondins

(2011) J. C. Adams et al.   Cold Spring Harbor Perspectives in Biology

Epigenetic Regulation of Thy-1 by Histone Deacetylase Inhibitor in Rat Lung Fibroblasts

(2010) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Assembly of Fibronectin Extracellular Matrix

(2010) Purva Singh et al.   Annual Review of Cell and Developmental Biology

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IgE, mast cells, basophils, and eosinophils

(2010) Kelly D. Stone et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Thy-1-Integrin αvβ5Interactions Inhibit Lung Fibroblast Contraction-induced Latent Transforming Growth Factor-β1 Activation and Myofibroblast Differentiation

(2010) Yong Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SPARC Suppresses Apoptosis of Idiopathic Pulmonary Fibrosis Fibroblasts through Constitutive Activation of β-Catenin

(2010) Wenteh Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biomaterial topography alters healing in vivo and monocyte/macrophage activation in vitro

(2010) Paige C. S. Bota et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

(2010) Mark S. Wilson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells

(2010) L. Lu et al.   JOURNAL OF IMMUNOLOGY

Blockade of interaction of α9 integrin with its ligands hinders the formation of granulation in cutaneous wound healing

(2010) Yosuke Nakayama et al.   LABORATORY INVESTIGATION

Scarless Fetal Wound Healing: A Basic Science Review

(2010) Barrett J. Larson et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Guiding Epithelial Cell Phenotypes with Engineered Integrin-Specific Recombinant Fibronectin Fragments

(2010) Ashley C. Brown et al.   TISSUE ENGINEERING PART A

Continuing Education Course #2: Current Understanding of Hemostasis

(2010) Andrew J. Gale   TOXICOLOGIC PATHOLOGY

Gene Expression Profiling of Pulmonary Fibrosis Identifies Twist1 as an Antiapoptotic Molecular “Rectifier” of Growth Factor Signaling

(2009) Robert S. Bridges et al.   AMERICAN JOURNAL OF PATHOLOGY

TREM and TREM-like receptors in inflammation and disease

(2009) Jill W Ford et al.   CURRENT OPINION IN IMMUNOLOGY

Differential apoptosis markers in human keloids and hypertrophic scars fibroblasts

(2009) Bruna De Felice et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Interaction of Wingless Protein (Wnt), Transforming Growth Factor-β1, and Hyaluronan Production in Fetal and Postnatal Fibroblasts

(2009) Antoine L. Carre et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Clustering of  5 1 integrins determines adhesion strength whereas  v 3 and talin enable mechanotransduction

(2009) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prostaglandin E2 differentially regulates contraction and structural reorganization of anchored collagen gels by human adult and fetal dermal fibroblasts

(2009) Aron Parekh et al.   WOUND REPAIR AND REGENERATION

S-nitrosylation of caspase-3 is the mechanism by which adhesion fibroblasts manifest lower apoptosis

(2009) Zhong L. Jiang et al.   WOUND REPAIR AND REGENERATION

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

(2009) John T. Pesce et al.   PLoS Pathogens

The role of SPARC in extracellular matrix assembly

(2009) Amy D. Bradshaw   Journal of Cell Communication and Signaling

The role of tenascin-C in tissue injury and tumorigenesis

(2009) Kim S. Midwood et al.   Journal of Cell Communication and Signaling

Thy-1 Promoter Hypermethylation

(2008) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring

(2008) Ryoichi Mori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

An Essential Role for Fibronectin Extra Type III Domain A in Pulmonary Fibrosis

(2007) Andrés F. Muro et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Prothrombotic Effects of Fibronectin Isoforms Containing the EDA Domain

(2007) Anil K. Chauhan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY