Fibroblasts probe substrate rigidity with filopodia extensions before occupying an area

Protrusion Fluctuations Direct Cell Motion

(2014) David Caballero et al.   BIOPHYSICAL JOURNAL

Substrates with Engineered Step Changes in Rigidity Induce Traction Force Polarity and Durotaxis

(2013) Mark T. Breckenridge et al.   Cellular and Molecular Bioengineering

The Formin Daam1 and Fascin Directly Collaborate to Promote Filopodia Formation

(2013) Richa Jaiswal et al.   CURRENT BIOLOGY

Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

(2013) A. Steffen et al.   JOURNAL OF CELL SCIENCE

The role of filopodia in the recognition of nanotopographies

(2013) Jörg Albuschies et al.   Scientific Reports

The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices

(2012) Yu Suk Choi et al.   BIOMATERIALS

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

Arp2/3 Is Critical for Lamellipodia and Response to Extracellular Matrix Cues but Is Dispensable for Chemotaxis

(2012) Congying Wu et al.   CELL

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain

(2012) Matthew Raab et al.   JOURNAL OF CELL BIOLOGY

The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration

(2012) Praveen Suraneni et al.   JOURNAL OF CELL BIOLOGY

Fabrication of Hydrogels with Steep Stiffness Gradients for Studying Cell Mechanical Response

(2012) Raimon Sunyer et al.   PLoS One

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

(2012) L. Trichet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elasticity boundary conditions required for cell mechanotaxis on microelastically-patterned gels

(2011) Takahito Kawano et al.   BIOMATERIALS

Assessing the spatial resolution of cellular rigidity sensing using a micropatterned hydrogel–photoresist composite

(2011) Ian T. Hoffecker et al.   LAB ON A CHIP

The regulation of traction force in relation to cell shape and focal adhesions

(2010) Andrew D. Rape et al.   BIOMATERIALS

RANKL inhibition decreases the incidence of mammary adenocarcinomas in wild type (WT) and MMTV-RANK transgenic mice.

(2010) D Branstetter et al.   CANCER RESEARCH

Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype

(2010) Robert W. Tilghman et al.   PLoS One

The role of formins in filopodia formation

(2009) Harry Mellor   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

PEGDA hydrogels with patterned elasticity: Novel tools for the study of cell response to substrate rigidity

(2009) Stephanie Nemir et al.   BIOTECHNOLOGY AND BIOENGINEERING

Characterization of two classes of small molecule inhibitors of Arp2/3 complex

(2009) B. J. Nolen et al.   NATURE

A photo-modulatable material for probing cellular responses to substrate rigidity

(2009) Margo T. Frey et al.   Soft Matter

Traction Dynamics of Filopodia on Compliant Substrates

(2008) C. E. Chan et al.   SCIENCE

Effect of Scaffold Stiffness on Myoblast Differentiation

(2008) Meital Levy-Mishali et al.   TISSUE ENGINEERING PART A