αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin

Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation

(2016) Zhiqi Sun et al.   NATURE CELL BIOLOGY

Relating conformation to function in integrin α5β1

(2016) Yang Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

(2016) Marina Theodosiou et al.   eLife

Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin

(2016) Dimitris Missirlis et al.   Scientific Reports

Regulation of integrin-mediated adhesions

(2015) Daniel V Iwamoto et al.   CURRENT OPINION IN CELL BIOLOGY

Nascent Integrin Adhesions Form on All Matrix Rigidities after Integrin Activation

(2015) Rishita Changede et al.   DEVELOPMENTAL CELL

The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions

(2015) H. E. Balcioglu et al.   JOURNAL OF CELL SCIENCE

The α v β 1 integrin plays a critical in vivo role in tissue fibrosis

(2015) Nilgun I. Reed et al.   Science Translational Medicine

Increasing throughput of AFM-based single cell adhesion measurements through multisubstrate surfaces

(2015) Miao Yu et al.   Beilstein Journal of Nanotechnology

In PC3 prostate cancer cells ephrin receptors crosstalk to β1-integrins to strengthen adhesion to collagen type I

(2015) Miao Yu et al.   Scientific Reports

Assay for characterizing the recovery of vertebrate cells for adhesion measurements by single-cell force spectroscopy

(2014) Rajib Schubert et al.   FEBS LETTERS

Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing

(2014) Perrine Pinon et al.   JOURNAL OF CELL BIOLOGY

Rigidity sensing and adaptation through regulation of integrin types

(2014) Alberto Elosegui-Artola et al.   NATURE MATERIALS

The integrin adhesome: from genes and proteins to human disease

(2014) Sabina E. Winograd-Katz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FHOD1 Is Needed for Directed Forces and Adhesion Maturation during Cell Spreading and Migration

(2013) Thomas Iskratsch et al.   DEVELOPMENTAL CELL

Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation

(2013) Weizhi Liu et al.   MOLECULAR CELL

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

(2013) Herbert B. Schiller et al.   NATURE CELL BIOLOGY

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct Roles of Talin and Kindlin in Regulating Integrin α5β1 Function and Trafficking

(2012) Coert Margadant et al.   CURRENT BIOLOGY

Integrin-linked kinase at a glance

(2012) M. Widmaier et al.   JOURNAL OF CELL SCIENCE

Osteoblast mineralization requires β1 integrin/ICAP-1–dependent fibronectin deposition

(2011) Molly Brunner et al.   JOURNAL OF CELL BIOLOGY

Integrin Structure, Activation, and Interactions

(2011) I. D. Campbell et al.   Cold Spring Harbor Perspectives in Biology

Quantifying cellular adhesion to extracellular matrix components by single-cell force spectroscopy

(2010) Jens Friedrichs et al.   Nature Protocols

Integrins as therapeutic targets: lessons and opportunities

(2010) Dermot Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Stimulated single-cell force spectroscopy to quantify cell adhesion receptor crosstalk

(2010) Jens Friedrichs et al.   PROTEOMICS

How ILK and kindlins cooperate to orchestrate integrin signaling

(2009) Ralph T Böttcher et al.   CURRENT OPINION IN CELL BIOLOGY

Giving off mixed signals-Distinct functions of α5β1and αvβ3integrins in regulating cell behaviour

(2009) Mark R. Morgan et al.   IUBMB LIFE

Kindlin-1 and -2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects

(2009) David S. Harburger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

Force probing surfaces of living cells to molecular resolution

(2009) Daniel J Müller et al.   Nature Chemical Biology

Clustering of  5 1 integrins determines adhesion strength whereas  v 3 and talin enable mechanotransduction

(2009) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell adaptive response to extracellular matrix density is controlled by ICAP-1–dependent β1-integrin affinity

(2008) Angélique Millon-Frémillon et al.   JOURNAL OF CELL BIOLOGY

Single-cell force spectroscopy

(2008) J. Helenius et al.   JOURNAL OF CELL SCIENCE

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY