Glycosaminoglycan-based hydrogels capture inflammatory chemokines and rescue defective wound healing in mice

Glycosaminoglycan-Based Biohybrid Hydrogels: A Sweet and Smart Choice for Multifunctional Biomaterials

(2016) Uwe Freudenberg et al.   ADVANCED MATERIALS

TGFβ functionalized starPEG-heparin hydrogels modulate human dermal fibroblast growth and differentiation

(2015) Akira Watarai et al.   Acta Biomaterialia

Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions

(2015) P. R. B. Joseph et al.   BIOCHEMICAL JOURNAL

Multilayer hydrogel coatings to combine hemocompatibility and antimicrobial activity

(2015) Marion Fischer et al.   BIOMATERIALS

Porcine Models of Cutaneous Wound Healing

(2015) M. Seaton et al.   ILAR JOURNAL

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

(2015) Uwe Freudenberg et al.   JOURNAL OF CONTROLLED RELEASE

Controlling the Balance of Fibroblast Proliferation and Differentiation: Impact of Thy-1

(2015) Manuela Schmidt et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Heparan sulfate and heparin interactions with proteins

(2015) Maria C. Z. Meneghetti et al.   Journal of the Royal Society Interface

Tissue-engineered 3D tumor angiogenesis models: Potential technologies for anti-cancer drug discovery

(2014) Karolina Chwalek et al.   ADVANCED DRUG DELIVERY REVIEWS

Biohybrid Networks of Selectively Desulfated Glycosaminoglycans for Tunable Growth Factor Delivery

(2014) Andrea Zieris et al.   BIOMACROMOLECULES

Unconventional apoptosis of polymorphonuclear neutrophils (PMN): staurosporine delays exposure of phosphatidylserine and prevents phagocytosis by MΦ-2 macrophages of PMN

(2014) S. Franz et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Docking Server for the Identification of Heparin Binding Sites on Proteins

(2014) Scott E. Mottarella et al.   Journal of Chemical Information and Modeling

A Combinatorial Approach to Biophysically Characterise Chemokine-Glycan Binding Affinities for Drug Development

(2014) Tanja Gerlza et al.   MOLECULES

Growth Factors Engineered for Super-Affinity to the Extracellular Matrix Enhance Tissue Healing

(2014) M. M. Martino et al.   SCIENCE

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Atherosclerosis--Multiple Pathways to Lesional Macrophages

(2014) C. Schulz et al.   Science Translational Medicine

Clinical application of growth factors and cytokines in wound healing

(2014) Stephan Barrientos et al.   WOUND REPAIR AND REGENERATION

Defined Polymer-Peptide Conjugates to Form Cell-Instructive starPEG-Heparin Matrices In Situ

(2013) Mikhail V. Tsurkan et al.   ADVANCED MATERIALS

Investigation of lysine side chain interactions of interleukin-8 with heparin and other glycosaminoglycans studied by a methylation-NMR approach

(2013) K. Mobius et al.   GLYCOBIOLOGY

How good is automated protein docking?

(2013) Dima Kozakov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Chemokines and Their Receptors Are Key Players in the Orchestra That Regulates Wound Healing

(2013) Manuela Martins-Green et al.   Advances in Wound Care

Artificial extracellular matrices composed of collagen I and high-sulfated hyaluronan promote phenotypic and functional modulation of human pro-inflammatory M1 macrophages

(2012) Sandra Franz et al.   Acta Biomaterialia

Using Mean Field Theory to Guide Biofunctional Materials Design

(2012) Uwe Freudenberg et al.   ADVANCED FUNCTIONAL MATERIALS

The influence of glycosaminoglycans on IL-8-mediated functions of neutrophils

(2012) Denise Schlorke et al.   CARBOHYDRATE RESEARCH

Acute and Impaired Wound Healing

(2012) Tatiana N. Demidova-Rice et al.   Advances in Skin & Wound Care

Engineering the Regenerative Microenvironment with Biomaterials

(2012) Jeffrey J. Rice et al.   Advanced Healthcare Materials

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Engineering the Growth Factor Microenvironment with Fibronectin Domains to Promote Wound and Bone Tissue Healing

(2011) M. M. Martino et al.   Science Translational Medicine

The Mysterious Ways of the Chemokine CXCL5

(2010) Ekaterina K. Koltsova et al.   IMMUNITY

Differential Proteomic Analysis Distinguishes Tissue Repair Biomarker Signatures in Wound Exudates Obtained from Normal Healing and Chronic Wounds

(2010) Sabine A. Eming et al.   JOURNAL OF PROTEOME RESEARCH

A star-PEG–heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases

(2009) Uwe Freudenberg et al.   BIOMATERIALS

Locally available heparin modulates inflammatory cell recruitment in a manner independent of anticoagulant activity

(2009) Rebecca Lever et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Chemokine patterning by glycosaminoglycans and interceptors

(2009) Antal Rot   Frontiers in Bioscience-Landmark

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Update on heparin: what do we need to know?

(2009) Daniel S. Weitz et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Inflammatory cytokine levels in chronic venous insufficiency ulcer tissue before and after compression therapy

(2009) Stephanie K. Beidler et al.   JOURNAL OF VASCULAR SURGERY

Shaping Morphogen Gradients by Proteoglycans

(2009) D. Yan et al.   Cold Spring Harbor Perspectives in Biology

Biologic therapeutics and molecular profiling to optimize wound healing

(2008) Marie N. Menke et al.   GYNECOLOGIC ONCOLOGY

In vivo measurements of the elastic mechanical properties of human skin by indentation tests

(2007) C. Pailler-Mattei et al.   MEDICAL ENGINEERING & PHYSICS