标题
The calcium–iron connection in ferroptosis-mediated neuronal death
作者
关键词
Calcium, Iron, Ferroptosis, Reactive oxygen species, Oxidative stress, Calcium release channels, Neurodegeneration, Ferroptosis inhibitors
出版物
FREE RADICAL BIOLOGY AND MEDICINE
Volume 175, Issue -, Pages 28-41
出版商
Elsevier BV
发表日期
2021-08-27
DOI
10.1016/j.freeradbiomed.2021.08.231
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Ferroptosis: mechanisms, biology and role in disease
- (2021) Xuejun Jiang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Infantile Iron Deficiency Affects Brain Development in Monkeys Even After Treatment of Anemia
- (2021) Roza M. Vlasova et al. Frontiers in Human Neuroscience
- Crosstalk between nucleus and mitochondria in human disease: Mitochondrial iron and calcium homeostasis in Friedreich ataxia
- (2021) Jordi Tamarit et al. IUBMB LIFE
- New Insights into the Role of Ferritin in Iron Homeostasis and Neurodegenerative Diseases
- (2021) Na Zhang et al. MOLECULAR NEUROBIOLOGY
- Presynaptic store-operated Ca2+ entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress
- (2021) Natali L. Chanaday et al. NEURON
- Oxidative stress and regulated cell death in Parkinson’s disease
- (2021) P.A. Dionísio et al. AGEING RESEARCH REVIEWS
- Ferroptosis and its potential as a therapeutic target
- (2021) Hanshu Yuan et al. BIOCHEMICAL PHARMACOLOGY
- Ferroptosis: Biochemistry and Biology in Cancers
- (2021) Zhiyuan Shi et al. Frontiers in Oncology
- Iron induces two distinct Ca2+ signalling cascades in astrocytes
- (2021) Wenzheng Guan et al. Communications Biology
- Involvement of ferroptosis in human motor neuron cell death
- (2021) Tsuyoshi Matsuo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Super-enhancer-driven Sorting Nexin 5 expression promotes dopaminergic neuronal ferroptosis in Parkinson's disease models
- (2021) Wenwen Si et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ryanodine receptor-mediated Ca2+ release and atlastin-2 GTPase activity contribute to IP3-induced dendritic Ca2+ signals in primary hippocampal neurons
- (2021) Omar A. Ramírez et al. CELL CALCIUM
- Where have all the Orais gone? Commentary on “Orai1 channels are essential for amplification of glutamate-evoked Ca2+ signals in dendritic spines to regulate working and associative memory”
- (2021) Jana Hartmann et al. CELL CALCIUM
- RyR-mediated Ca2+ release elicited by neuronal activity induces nuclear Ca2+ signals, CREB phosphorylation, and Npas4/RyR2 expression
- (2021) Pedro Lobos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The mRNA Decay Factor CAR-1/LSM14 Regulates Axon Regeneration via Mitochondrial Calcium Dynamics
- (2020) Ngang Heok Tang et al. CURRENT BIOLOGY
- Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma
- (2020) Yongfei Yang et al. Nature Communications
- Iron Metabolism, Ferroptosis, and the Links With Alzheimer’s Disease
- (2020) Nao Yan et al. Frontiers in Neuroscience
- Protein Kinase C Isozymes and Autophagy during Neurodegenerative Disease Progression
- (2020) Humeyra Nur Kaleli et al. Cells
- Reduced Sulfation Enhanced Oxytosis and Ferroptosis in Mouse Hippocampal HT22 Cells
- (2020) Haruna Nagase et al. Biomolecules
- Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
- (2020) Plamena R. Angelova et al. CELL DEATH AND DIFFERENTIATION
- Harmful Iron-Calcium Relationship in Pantothenate kinase Associated Neurodegeneration
- (2020) Paolo Santambrogio et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer’s Disease and Parkinson’s Disease
- (2020) Giacomo Monzio Compagnoni et al. MOLECULAR NEUROBIOLOGY
- Oxidative Stress in Cognitive and Epigenetic Aging: A Retrospective Glance
- (2020) Aditi Kandlur et al. Frontiers in Molecular Neuroscience
- Proeryptotic Activity of 4-Hydroxynonenal: A New Potential Physiopathological Role for Lipid Peroxidation Products
- (2020) Mario Allegra et al. Biomolecules
- Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis
- (2020) Germán Plascencia-Villa et al. ANTIOXIDANTS & REDOX SIGNALING
- Redox modifications in synaptic components as biomarkers of cognitive status, in brain aging and disease
- (2020) Pablo Muñoz et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Basics and principles of cellular and systemic iron homeostasis
- (2020) Angeliki Katsarou et al. MOLECULAR ASPECTS OF MEDICINE
- Overdosing on iron: Elevated iron and degenerative brain disorders
- (2020) Santosh R D’Mello et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy
- (2020) Shalini S. Rao et al. JOURNAL OF ALZHEIMERS DISEASE
- Role of reactive oxygen species in the progression of Alzheimer’s disease
- (2020) Shvetank Bhatt et al. DRUG DISCOVERY TODAY
- Ferroptosis Mechanisms Involved in Neurodegenerative Diseases
- (2020) Cadiele Oliana Reichert et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Orai1 Channels Are Essential for Amplification of Glutamate-Evoked Ca2+ Signals in Dendritic Spines to Regulate Working and Associative Memory
- (2020) Mohammad Mehdi Maneshi et al. Cell Reports
- Iron Metabolism and Ferroptosis in Epilepsy
- (2020) Shuang Chen et al. Frontiers in Neuroscience
- Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review
- (2019) Pengxu Lei et al. Frontiers in Physiology
- Iron in Neurodegeneration – Cause or Consequence?
- (2019) Alain Ndayisaba et al. Frontiers in Neuroscience
- Noxious Iron–Calcium Connections in Neurodegeneration
- (2019) Marco Tulio Núñez et al. Frontiers in Neuroscience
- Calcium Sensors in Neuronal Function and Dysfunction
- (2019) Robert D. Burgoyne et al. Cold Spring Harbor Perspectives in Biology
- GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis
- (2019) Giovanni C. Forcina et al. PROTEOMICS
- Iron concentrations in neurons and glial cells with estimates on ferritin concentrations
- (2019) Anja Reinert et al. BMC NEUROSCIENCE
- STIM Proteins and Glutamate Receptors in Neurons: Role in Neuronal Physiology and Neurodegenerative Diseases
- (2019) Karolina Serwach et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Crosstalk between Calcium and ROS in Pathophysiological Conditions
- (2019) Simona Feno et al. Oxidative Medicine and Cellular Longevity
- Brain iron transport
- (2019) Zhong‐Ming Qian et al. BIOLOGICAL REVIEWS
- Two types of functionally distinct Ca2+ stores in hippocampal neurons
- (2019) Hsing-Jung Chen-Engerer et al. Nature Communications
- ESCRT-III–dependent membrane repair blocks ferroptosis
- (2019) Enyong Dai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondria regulation in ferroptosis
- (2019) Hai Wang et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- FSP1 is a glutathione-independent ferroptosis suppressor
- (2019) Sebastian Doll et al. NATURE
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
- (2019) Kirill Bersuker et al. NATURE
- Iron homeostasis and oxidative stress: An intimate relationship
- (2019) Dimitrios Galaris et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Role of Endoplasmic Reticulum-Mediated Ca2+ Signaling in Neuronal Cell Death
- (2018) Yohei Okubo et al. ANTIOXIDANTS & REDOX SIGNALING
- Ryanodine receptor dysfunction in human disorders
- (2018) Alexander Kushnir et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The role of Ca 2+ in cell death caused by oxidative glutamate toxicity and ferroptosis
- (2018) Pamela Maher et al. CELL CALCIUM
- Calcium signaling and molecular mechanisms underlying neurodegenerative diseases
- (2018) Ekaterina Pchitskaya et al. CELL CALCIUM
- Functional Roles of Astrocyte Calcium Elevations: From Synapses to Behavior
- (2018) Sónia Guerra-Gomes et al. Frontiers in Cellular Neuroscience
- The Aging of Iron Man
- (2018) Azhaar Ashraf et al. Frontiers in Aging Neuroscience
- Critical review: involvement of endoplasmic reticulum stress in the aetiology of Alzheimer's disease
- (2018) Shoko Hashimoto et al. Open Biology
- Oxytosis/Ferroptosis—(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System
- (2018) Jan Lewerenz et al. Frontiers in Neuroscience
- Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
- (2018) Ron Shah et al. ACS Central Science
- Striking while the iron is hot: Iron metabolism and Ferroptosis in neurodegeneration
- (2018) Shashank Masaldan et al. FREE RADICAL BIOLOGY AND MEDICINE
- Increased Iron Levels and Decreased Tissue Integrity in Hippocampus of Alzheimer's Disease Detected in vivo with Magnetic Resonance Imaging
- (2018) Erika P. Raven et al. JOURNAL OF ALZHEIMERS DISEASE
- Redox regulation of type-I inositol trisphosphate receptors in intact mammalian cells
- (2018) Suresh K. Joseph et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ferritinophagy/ferroptosis: Iron-related newcomers in human diseases
- (2018) Mingzhu Tang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Ferroptosis, a Recent Defined Form of Critical Cell Death in Neurological Disorders
- (2018) Jia-rui Wu et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Altered ER–mitochondria contact impacts mitochondria calcium homeostasis and contributes to neurodegeneration in vivo in disease models
- (2018) Kyu-Sun Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Mitochondria in Ferroptosis
- (2018) Minghui Gao et al. MOLECULAR CELL
- Ferroptosis and Its Role in Diverse Brain Diseases
- (2018) Abigail Weiland et al. MOLECULAR NEUROBIOLOGY
- Cellular calcium signaling in the aging brain
- (2017) Remya Chandran et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Iron metabolism and its detection through MRI in parkinsonian disorders: a systematic review
- (2017) Sara Pietracupa et al. NEUROLOGICAL SCIENCES
- Ferroptosis Inhibition: Mechanisms and Opportunities
- (2017) Jose Pedro Friedmann Angeli et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- RyR2-Mediated Ca2+ Release and Mitochondrial ROS Generation Partake in the Synaptic Dysfunction Caused by Amyloid β Peptide Oligomers
- (2017) Carol D. SanMartín et al. Frontiers in Molecular Neuroscience
- BID links ferroptosis to mitochondrial cell death pathways
- (2017) Sandra Neitemeier et al. Redox Biology
- Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
- (2017) William Sealy Hambright et al. Redox Biology
- Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking
- (2016) Bruce E. Herring et al. Annual Review of Physiology
- Autophagy promotes ferroptosis by degradation of ferritin
- (2016) Wen Hou et al. Autophagy
- Ferroptosis: process and function
- (2016) Y Xie et al. CELL DEATH AND DIFFERENTIATION
- Mitochondria-associated ER membranes and Alzheimer disease
- (2016) Estela Area-Gomez et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Mitochondrial control of cell bioenergetics in Parkinson’s disease
- (2016) Raquel Requejo-Aguilar et al. FREE RADICAL BIOLOGY AND MEDICINE
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC
- (2016) Bruce Do Van et al. NEUROBIOLOGY OF DISEASE
- Calcium, Reactive Oxygen Species, and Synaptic Plasticity
- (2016) Cecilia Hidalgo et al. PHYSIOLOGY
- Familial Alzheimer’s disease–associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+entry
- (2016) Benjamin Chun-Kit Tong et al. Science Signaling
- Iron overload-induced calcium signals modulate mitochondrial fragmentation in HT-22 hippocampal neuron cells
- (2016) Dong Gil Lee et al. TOXICOLOGY
- Familial Alzheimer’s disease–associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+entry
- (2016) Benjamin Chun-Kit Tong et al. Science Signaling
- N-Acetyl Cysteine May Support Dopamine Neurons in Parkinson's Disease: Preliminary Clinical and Cell Line Data
- (2016) Daniel A. Monti et al. PLoS One
- Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment
- (2016) J. M. G. van Bergen et al. Scientific Reports
- Mammalian lipoxygenases and their biological relevance
- (2015) Hartmut Kuhn et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Brain Glutathione Levels – A Novel Biomarker for Mild Cognitive Impairment and Alzheimer’s Disease
- (2015) Pravat K. Mandal et al. BIOLOGICAL PSYCHIATRY
- Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation
- (2015) M Hayano et al. CELL DEATH AND DIFFERENTIATION
- Role of extracellular Hydrogen peroxide in regulation of iron homeostasis genes in neuronal cells: Implication in iron accumulation
- (2015) Som Dev et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis
- (2015) Liuji Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease
- (2015) H. Zhang et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders
- (2015) Natalia P. Mena et al. MITOCHONDRION
- The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin
- (2015) Douglas G. Peters et al. NEUROBIOLOGY OF DISEASE
- Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE
- (2015) Scott Ayton et al. Nature Communications
- Calcium and ROS: A mutual interplay
- (2015) Agnes Görlach et al. Redox Biology
- Contribution of Ca2+ Release Channels to Hippocampal Synaptic Plasticity and Spatial Memory: Potential Redox Modulation
- (2014) Andrea C. Paula-Lima et al. ANTIOXIDANTS & REDOX SIGNALING
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Neuronal calcium signaling: function and dysfunction
- (2014) Marisa Brini et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The role of iron in brain ageing and neurodegenerative disorders
- (2014) Roberta J Ward et al. LANCET NEUROLOGY
- Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson’s disease
- (2014) Scott Ayton et al. Molecular Neurodegeneration
- MRI for Iron Mapping in Alzheimer's Disease
- (2014) Christian Langkammer et al. Neurodegenerative Diseases
- Reduced Synaptic STIM2 Expression and Impaired Store-Operated Calcium Entry Cause Destabilization of Mature Spines in Mutant Presenilin Mice
- (2014) Suya Sun et al. NEURON
- Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
- (2014) Scott J Dixon et al. eLife
- The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders
- (2014) Pamela J. Urrutia et al. Frontiers in Pharmacology
- Labile iron in cells and body fluids: physiology, pathology, and pharmacology
- (2014) Zvi Ioav Cabantchik Frontiers in Pharmacology
- The IRP/IRE system in vivo: insights from mouse models
- (2014) Nicole Wilkinson et al. Frontiers in Pharmacology
- Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease
- (2013) David Devos et al. ANTIOXIDANTS & REDOX SIGNALING
- Brain Iron Homeostasis: From Molecular Mechanisms To Clinical Significance and Therapeutic Opportunities
- (2013) Neena Singh et al. ANTIOXIDANTS & REDOX SIGNALING
- Blocking of L-type calcium channels protects hippocampal and nigral neurons against iron neurotoxicity The role of L-type calcium channels in iron-induced neurotoxicity
- (2013) M. Ömer Bostanci et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells
- (2013) Pamela Urrutia et al. JOURNAL OF NEUROCHEMISTRY
- Iron levels in the human brain: A post-mortem study of anatomical region differences and age-related changes
- (2013) Patrícia Ramos et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- The synaptic maintenance problem: membrane recycling, Ca2+ homeostasis and late onset degeneration
- (2013) Ilya Bezprozvanny et al. Molecular Neurodegeneration
- The role of iron and reactive oxygen species in cell death
- (2013) Scott J Dixon et al. Nature Chemical Biology
- Nuclear calcium signalling in the regulation of brain function
- (2013) Hilmar Bading NATURE REVIEWS NEUROSCIENCE
- The role of intracellular calcium stores in synaptic plasticity and memory consolidation
- (2013) Kathryn D. Baker et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress
- (2013) N Henke et al. Cell Death & Disease
- -Synuclein in Parkinson's Disease
- (2013) L. Stefanis Cold Spring Harbor Perspectives in Medicine
- Iron toxicity in neurodegeneration
- (2012) Marco T. Núñez et al. BIOMETALS
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Multiple Defects in Energy Metabolism in Alzheimers Disease
- (2012) I. L. Ferreira et al. CURRENT DRUG TARGETS
- Association between neonatal iron overload and early human brain development in premature infants
- (2012) Sanjiv B. Amin et al. EARLY HUMAN DEVELOPMENT
- Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
- (2012) Peng Lei et al. NATURE MEDICINE
- Calcium and cell death mechanisms: A perspective from the cell death community
- (2011) Boris Zhivotovsky et al. CELL CALCIUM
- BID regulates AIF-mediated caspase-independent necroptosis by promoting BAX activation
- (2011) L Cabon et al. CELL DEATH AND DIFFERENTIATION
- Role of calcineurin in neurodegeneration produced by misfolded proteins and endoplasmic reticulum stress
- (2011) Abhisek Mukherjee et al. CURRENT OPINION IN CELL BIOLOGY
- Iron MediatesN-Methyl-d-aspartate Receptor-dependent Stimulation of Calcium-induced Pathways and Hippocampal Synaptic Plasticity
- (2011) Pablo Muñoz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease
- (2011) Angela M. Bruno et al. NEUROBIOLOGY OF AGING
- Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions
- (2011) Rui O. Costa et al. NEUROBIOLOGY OF AGING
- Iron handling in hippocampal neurons: activity-dependent iron entry and mitochondria-mediated neurotoxicity
- (2010) Ilaria Pelizzoni et al. AGING CELL
- Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca2+ Release Inducing Mitochondrial Fragmentation in Hippocampal Neurons and Prevent RyR-Mediated Dendritic Spine Remodeling Produced by BDNF
- (2010) Andrea C. Paula-Lima et al. ANTIOXIDANTS & REDOX SIGNALING
- Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory
- (2010) Cynthia A. Massaad et al. ANTIOXIDANTS & REDOX SIGNALING
- Activity-dependent calcium signaling and ERK-MAP kinases in neurons: A link to structural plasticity of the nucleus and gene transcription regulation
- (2010) J. Simon Wiegert et al. CELL CALCIUM
- Redox Sensitive Calcium Stores Underlie Enhanced After Hyperpolarization of Aged Neurons: Role for Ryanodine Receptor Mediated Calcium Signaling
- (2010) Karthik Bodhinathan et al. JOURNAL OF NEUROPHYSIOLOGY
- Calcium Signalling and Alzheimer’s Disease
- (2010) Michael J. Berridge NEUROCHEMICAL RESEARCH
- Ca2+ transfer from the ER to mitochondria: When, how and why
- (2009) Rosario Rizzuto et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD
- (2009) Tanea T. Reed et al. BRAIN RESEARCH
- Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options
- (2009) Bayani Uttara et al. Current Neuropharmacology
- Oxidative stress upregulates the NMDA receptor on cerebrovascular endothelium
- (2009) Christian Betzen et al. FREE RADICAL BIOLOGY AND MEDICINE
- NMDA Receptor Activation Increases Free Radical Production through Nitric Oxide and NOX2
- (2009) H. Girouard et al. JOURNAL OF NEUROSCIENCE
- Deviant Ryanodine Receptor-Mediated Calcium Release Resets Synaptic Homeostasis in Presymptomatic 3xTg-AD Mice
- (2009) S. Chakroborty et al. JOURNAL OF NEUROSCIENCE
- Calcium signaling in neurodegeneration
- (2009) Philippe Marambaud et al. Molecular Neurodegeneration
- NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation
- (2009) Angela M Brennan et al. NATURE NEUROSCIENCE
- Quantitative MR Phase-corrected Imaging to Investigate Increased Brain Iron Deposition of Patients with Alzheimer Disease
- (2009) Wen-zhen Zhu et al. RADIOLOGY
- Calcium signaling and neurodegenerative diseases
- (2009) Ilya Bezprozvanny TRENDS IN MOLECULAR MEDICINE
- Endoplasmic Reticulum Stress in Disease Pathogenesis
- (2008) Jonathan H. Lin et al. Annual Review of Pathology-Mechanisms of Disease
- Intracellular Iron Transport and Storage: From Molecular Mechanisms to Health Implications
- (2008) Elizabeth L. Mackenzie et al. ANTIOXIDANTS & REDOX SIGNALING
- Crosstalk Between Calcium and Redox Signaling: From Molecular Mechanisms to Health Implications
- (2008) Cecilia Hidalgo et al. ANTIOXIDANTS & REDOX SIGNALING
- Iron and calcium in the central nervous system: a close relationship in health and sickness
- (2008) Ilaria Pelizzoni et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death
- (2008) E Norberg et al. CELL DEATH AND DIFFERENTIATION
- Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
- (2008) Alexander Seiler et al. Cell Metabolism
- Redox modulation of long-term potentiation in the hippocampus via regulation of the glycogen synthase kinase-3β pathway
- (2008) Fei Cai et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ischemia-elicited Oxidative Modulation of Ca2+/Calmodulin-dependent Protein Kinase II
- (2008) Pavan K. Shetty et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Superoxide-Induced Potentiation in the Hippocampus Requires Activation of Ryanodine Receptor Type 3 and ERK
- (2008) A. Tara Huddleston et al. JOURNAL OF NEUROPHYSIOLOGY
- Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
- (2008) Ilya Bezprozvanny et al. TRENDS IN NEUROSCIENCES
- Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis
- (2007) Andrew J. Farrall et al. NEUROBIOLOGY OF AGING
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started