The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Mechanisms of Oxidative Glutamate Toxicity: The Glutamate/Cystine Antiporter System xc¯ as a Neuroprotective Drug Target

(2012) Philipp Albrecht et al.   CNS & Neurological Disorders-Drug Targets

Stromal Interaction Molecule 1 (STIM1) Is Involved in the Regulation of Mitochondrial Shape and Bioenergetics and Plays a Role in Oxidative Stress

(2012) Nadine Henke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative translation initiation gives rise to two isoforms of Orai1 with distinct plasma membrane mobilities

(2012) M. Fukushima et al.   JOURNAL OF CELL SCIENCE

Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential

(2011) Rebecca Noack et al.   HUMAN MOLECULAR GENETICS

ORAI1 Deficiency Impairs Activated T Cell Death and Enhances T Cell Survival

(2011) K.-D. Kim et al.   JOURNAL OF IMMUNOLOGY

Activation of store-operated ICRAC by hydrogen peroxide

(2010) Morten Grupe et al.   CELL CALCIUM

A novel giant peroxisomal superoxide dismutase motif-containing protein

(2010) Diamandis Toutzaris et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox-mediated reciprocal regulation of SERCA and Na+–Ca2+ exchanger contributes to sarcoplasmic reticulum Ca2+ depletion in cardiac myocytes

(2010) Gabriela M. Kuster et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differential Redox Regulation of ORAI Ion Channels: A Mechanism to Tune Cellular Calcium Signaling

(2010) I. Bogeski et al.   Science Signaling

12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress

(2009) Stefanie Pallast et al.   JOURNAL OF NEUROCHEMISTRY

The Constitutively Active Orphan G-protein-coupled Receptor GPR39 Protects from Cell Death by Increasing Secretion of Pigment Epithelium-derived Growth Factor

(2008) Sonja Dittmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orai, STIM1 and iPLA2β: a view from a different perspective

(2008) Victoria M. Bolotina   JOURNAL OF PHYSIOLOGY-LONDON

The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers

(2008) Aubin Penna et al.   NATURE

Orai1 subunit stoichiometry of the mammalian CRAC channel pore

(2007) Olivier Mignen et al.   JOURNAL OF PHYSIOLOGY-LONDON