Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls

Isoliquiritin ameliorates depression by suppressing NLRP3-mediated pyroptosis via miRNA-27a/SYK/NF-κB axis

(2021) Yuanjie Li et al.   Journal of Neuroinflammation

Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway

(2021) Daniel Rand et al.   Pharmaceutics

Vesicular Transport Machinery in Brain Endothelial Cells: What We Know and What We Don`t

(2020) Andrea E. Toth et al.   CURRENT PHARMACEUTICAL DESIGN

EV-Ident: Identifying Tumor-Specific Extracellular Vesicles by Size Fractionation and Single-Vesicle Analysis

(2020) Dongyoung Kim et al.   ANALYTICAL CHEMISTRY

Exosomal noncoding RNAs in Glioma: biological functions and potential clinical applications

(2020) Jian Cheng et al.   Molecular Cancer

Helminth genome analysis reveals conservation of extracellular vesicle biogenesis pathways but divergence of RNA loading machinery between phyla

(2020) Adam P.S. Bennett et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A comprehensive review of nano drug delivery system in the treatment of CNS disorders

(2020) K.M. Asha Spandana et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Scavenging Reactive Lipids to Prevent Oxidative Injury

(2020) Linda S. May-Zhang et al.   Annual Review of Pharmacology and Toxicology

Exosomes as drug delivery systems: A brief overview and progress update

(2020) Suyash M. Patil et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance

(2020) Shubham Salunkhe et al.   JOURNAL OF CONTROLLED RELEASE

Targeted exosome coating gene-chem nanocomplex as “nanoscavenger” for clearing α-synuclein and immune activation of Parkinson’s disease

(2020) Linying Liu et al.   Science Advances

Folic acid-modified Exosome-PH20 enhances the efficiency of therapy via modulation of the tumor microenvironment and directly inhibits tumor cell metastasis

(2020) Chunxiang Feng et al.   Bioactive Materials

Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice

(2019) Huixin Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Current status of used protocols for mesenchymal stem cell differentiation: a focus on insulin producing, osteoblast-like and neural cells.

(2019) Hadi Rajabi et al.   Current Stem Cell Research & Therapy

Exosomes: biogenesis, biologic function and clinical potential

(2019) Yuan Zhang et al.   Cell and Bioscience

Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders

(2019) Nisim Perets et al.   NANO LETTERS

Blood-brain barrier receptors and transporters: an insight on their function and how to exploit them through nanotechnology

(2019) Rui Pedro Moura et al.   Expert Opinion on Drug Delivery

Immunomodulatory properties of MSC-derived exosomes armed with high affinity aptamer toward mylein as a platform for reducing multiple sclerosis clinical score

(2019) Fazileh Hosseini Shamili et al.   JOURNAL OF CONTROLLED RELEASE

RVG-modified exosomes derived from mesenchymal stem cells rescue memory deficits by regulating inflammatory responses in a mouse model of Alzheimer’s disease

(2019) Guo-hong Cui et al.   Immunity & Ageing

Surface modification of gold nanoparticles with neuron-targeted exosome for enhanced blood–brain barrier penetration

(2019) Mattaka Khongkow et al.   Scientific Reports

Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via Transcytosis

(2019) Golnaz Morad et al.   ACS Nano

Lidocaine turns the surface charge of biological membranes more positive and changes the permeability of blood-brain barrier culture models

(2019) Ana R. Santa-Maria et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Regulation of cargo export and sorting at the trans‐Golgi network

(2019) Rosaria Di Martino et al.   FEBS LETTERS

Astrocyte-Derived Paracrine Signals: Relevance for Neurogenic Niche Regulation and Blood–Brain Barrier Integrity

(2019) Simona Federica Spampinato et al.   Frontiers in Pharmacology

Systemic delivery of microRNA-21 antisense oligonucleotides to the brain using T7-peptide decorated exosomes

(2019) Gyeungyun Kim et al.   JOURNAL OF CONTROLLED RELEASE

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

(2019) Zhaogang Yang et al.   Nature Biomedical Engineering

Methotrexate-Loaded Extracellular Vesicles Functionalized with Therapeutic and Targeted Peptides for the Treatment of Glioblastoma Multiforme

(2018) Zhilan Ye et al.   ACS Applied Materials & Interfaces

Hypoxic glioblastoma release exosomal VEGF-A induce the permeability of blood-brain barrier

(2018) Chen Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

(2018) Tian Tian et al.   BIOMATERIALS

NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo

(2018) Gang Jia et al.   BIOMATERIALS

3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes

(2018) Marco Campisi et al.   BIOMATERIALS

TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice

(2018) Yuyan Cheng et al.   BRAIN BEHAVIOR AND IMMUNITY

Exosomes and Ectosomes in Intercellular Communication

(2018) Jacopo Meldolesi   CURRENT BIOLOGY

The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier

(2018) Junichi Matsumoto et al.   CURRENT PHARMACEUTICAL DESIGN

Endothelial colony-forming cell-derived exosomes restore blood-brain barrier continuity in mice subjected to traumatic brain injury

(2018) Weiwei Gao et al.   EXPERIMENTAL NEUROLOGY

Real-time acquisition of transendothelial electrical resistance in an all-human, in vitro, 3-dimensional, blood–brain barrier model exemplifies tight-junction integrity

(2018) Zaynah Maherally et al.   FASEB JOURNAL

Mechanisms of neuropsychiatric lupus: The relative roles of the blood-cerebrospinal fluid barrier versus blood-brain barrier

(2018) Sivan Gelb et al.   JOURNAL OF AUTOIMMUNITY

Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity

(2018) Arsalan S. Haqqani et al.   JOURNAL OF NEUROCHEMISTRY

Exosomes and their role in the intercellular trafficking of normal and disease associated prion proteins

(2018) Lesley Cheng et al.   MOLECULAR ASPECTS OF MEDICINE

Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: in vitro and in vivo evaluations

(2018) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Size matters in nanoscale communication

(2018) Andries Zijlstra et al.   NATURE CELL BIOLOGY

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

(2018) Haiying Zhang et al.   NATURE CELL BIOLOGY

Current trends and concepts in the design and development of nanogel carrier systems

(2018) P. N. Kendre et al.   POLYMER BULLETIN

Efficient RNA drug delivery using red blood cell extracellular vesicles

(2018) Waqas Muhammad Usman et al.   Nature Communications

Molecular Magnetic Resonance Imaging of Endothelial Activation in the Central Nervous System

(2018) Maxime Gauberti et al.   Theranostics

Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects

(2018) Rudimar L. Frozza et al.   Frontiers in Neuroscience

Exosome-Liposome Hybrid Nanoparticles Deliver CRISPR/Cas9 System in MSCs

(2018) Yao Lin et al.   Advanced Science

The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo.

(2018) Matthew A Odenwald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

StAR-related lipid transfer domain 11 (STARD11)–mediated ceramide transport mediates extracellular vesicle biogenesis

(2018) Masanori Fukushima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dopamine-loaded blood exosomes targeted to brain for better treatment of Parkinson's disease

(2018) Mengke Qu et al.   JOURNAL OF CONTROLLED RELEASE

Immune cell subset differentiation and tissue inflammation

(2018) Pu Fang et al.   Journal of Hematology & Oncology

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

(2018) Joseph A. Fraietta et al.   NATURE

Targeting extracellular vesicles to injured tissue using membrane cloaking and surface display

(2018) Travis J. Antes et al.   JOURNAL OF NANOBIOTECHNOLOGY

Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior

(2018) Raleigh M. Linville et al.   BIOMATERIALS

Intracellular transport and regulation of transcytosis across the blood–brain barrier

(2018) Roberto Villaseñor et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interaction between mesenchymal stromal cell-derived extracellular vesicles and immune cells by distinct protein content

(2018) Soura Mardpour et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Extracellular Vesicles Released by Glioblastoma Cells Stimulate Normal Astrocytes to Acquire a Tumor-Supportive Phenotype Via p53 and MYC Signaling Pathways

(2018) S. Hallal et al.   MOLECULAR NEUROBIOLOGY

Cluster of Differentiation 46 Is the Major Receptor in Human Blood–Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28)

(2018) Hiroki Kuroda et al.   MOLECULAR PHARMACEUTICS

Recent advancements in the use of exosomes as drug delivery systems

(2018) Edwin J. Bunggulawa et al.   JOURNAL OF NANOBIOTECHNOLOGY

Exosomes derived from mesenchymal stem cells attenuate inflammation and demyelination of the central nervous system in EAE rats by regulating the polarization of microglia

(2018) Zijian Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Selective knockout of astrocytic Na+ /H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke

(2017) Gulnaz Begum et al.   GLIA

Endosomal trafficking regulates receptor-mediated transcytosis of antibodies across the blood brain barrier

(2017) Arsalan S Haqqani et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli

(2017) Margaret Alexander et al.   JOURNAL OF IMMUNOLOGY

A novel cell-cell communication mechanism in the nervous system: exosomes

(2017) Guan Zhang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Increased Soluble VCAM-1 and Normal P-Selectin in Cystic Fibrosis: a Cross-Sectional Study

(2017) Jan K. Nowak et al.   LUNG

Hypoxia Selectively Enhances Integrin α 5 β 1 Receptor Expression in Breast Cancer to Promote Metastasis

(2017) Julia A. Ju et al.   MOLECULAR CANCER RESEARCH

Targeting the Central Nervous System (CNS): A Review of Rabies Virus-Targeting Strategies

(2017) Mira Oswald et al.   MOLECULAR PHARMACEUTICS

Topical tissue nano-transfection mediates non-viral stroma reprogramming and rescue

(2017) Daniel Gallego-Perez et al.   Nature Nanotechnology

Targeting blood-brain-barrier transcytosis – perspectives for drug delivery

(2017) Imre Mäger et al.   NEUROPHARMACOLOGY

Exosomes: Therapy delivery tools and biomarkers of diseases

(2017) Lucio Barile et al.   PHARMACOLOGY & THERAPEUTICS

A Critical Assessment of Exosomes in the Pathogenesis and Stratification of Parkinson’s Disease

(2017) George K. Tofaris   Journal of Parkinsons Disease

Overexpression of miR-210 and its significance in ischemic tissue damage

(2017) G. Zaccagnini et al.   Scientific Reports

Cellular Engineering with Membrane Fusogenic Liposomes to Produce Functionalized Extracellular Vesicles

(2016) Junsung Lee et al.   ACS Applied Materials & Interfaces

Blood Exosomes Endowed with Magnetic and Targeting Properties for Cancer Therapy

(2016) Hongzhao Qi et al.   ACS Nano

Advancement in integrin facilitated drug delivery

(2016) Daniela Arosio et al.   ADVANCED DRUG DELIVERY REVIEWS

Development of exosome surface display technology in living human cells

(2016) Zachary Stickney et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Microfluidic blood-brain barrier model provides in vivo-like barrier properties for drug permeability screening

(2016) Ying I. Wang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Bovine milk-derived exosomes for drug delivery

(2016) Radha Munagala et al.   CANCER LETTERS

Elucidation of Exosome Migration Across the Blood–Brain Barrier Model In Vitro

(2016) Claire C. Chen et al.   Cellular and Molecular Bioengineering

Targeted therapeutic delivery using engineered exosomes and its applications in cardiovascular diseases

(2016) Dang Xitong et al.   GENE

PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time

(2016) S.A.A. Kooijmans et al.   JOURNAL OF CONTROLLED RELEASE

Epidermal Growth Factor and Intestinal Barrier Function

(2016) Xiaopeng Tang et al.   MEDIATORS OF INFLAMMATION

Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys

(2016) Erica N. Borducchi et al.   NATURE

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of claudin/zonula occludens-1 complexes by hetero-claudin interactions

(2016) Barbara Schlingmann et al.   Nature Communications

Engineering hybrid exosomes by membrane fusion with liposomes

(2016) Yuko T. Sato et al.   Scientific Reports

Rab11a Mediates Vascular Endothelial-Cadherin Recycling and Controls Endothelial Barrier FunctionSignificance

(2015) Zhibo Yan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Diagnostic and therapeutic potentials of exosomes in CNS diseases

(2015) Ivana Kawikova et al.   BRAIN RESEARCH

Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites

(2015) Q. Wang et al.   CANCER RESEARCH

Modulation of Cellular Function Through Immune-Activated Exosomes

(2015) Lynn Pulliam et al.   DNA AND CELL BIOLOGY

Extracellular vesicles as carriers of microRNA, proteins and lipids in tumor microenvironment

(2015) Patrice Penfornis et al.   INTERNATIONAL JOURNAL OF CANCER

Solid lipid nanoparticles (SLN) of Efavirenz as lymph targeting drug delivery system: Elucidation of mechanism of uptake using chylomicron flow blocking approach

(2015) Vivek Makwana et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Exosomes as drug delivery vehicles for Parkinson's disease therapy

(2015) Matthew J. Haney et al.   JOURNAL OF CONTROLLED RELEASE

Construction of Chimeric Human Epidermal Growth Factor Containing Short Collagen-Binding Domain Moieties for Use as a Wound Tissue Healing Agent

(2015) Dong-Gyun Kim et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Microglia-derived HIV Nef+ exosome impairment of the blood–brain barrier is treatable by nanomedicine-based delivery of Nef peptides

(2015) A. D. Raymond et al.   JOURNAL OF NEUROVIROLOGY

Exogenous DNA Loading into Extracellular Vesicles via Electroporation is Size-Dependent and Enables Limited Gene Delivery

(2015) Tek N. Lamichhane et al.   MOLECULAR PHARMACEUTICS

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse

(2015) Yuchen Liu et al.   Scientific Reports

Combined treatment with a pH-sensitive fusogenic peptide and cationic lipids achieves enhanced cytosolic delivery of exosomes

(2015) Ikuhiko Nakase et al.   Scientific Reports

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

(2015) Jian Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Surface Functionalization of Exosomes Using Click Chemistry

(2014) Tyson Smyth et al.   BIOCONJUGATE CHEMISTRY

Tight junction dynamics: the role of junctional adhesion molecules (JAMs)

(2014) S. Garrido-Urbani et al.   CELL AND TISSUE RESEARCH

The blood-brain barrier: Structure, function and therapeutic approaches to cross it

(2014) Marta Tajes et al.   MOLECULAR MEMBRANE BIOLOGY

Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice

(2014) Xianjun Gao et al.   MOLECULAR THERAPY

Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

(2013) Su Chul Jang et al.   ACS Nano

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

Smart Stimuli Sensitive Nanogels in Cancer Drug Delivery and Imaging: A Review

(2013) S. Maya et al.   CURRENT PHARMACEUTICAL DESIGN

Carbodiimide versus Click Chemistry for Nanoparticle Surface Functionalization: A Comparative Study for the Elaboration of Multimodal Superparamagnetic Nanoparticles Targeting αvβ3 Integrins

(2013) Julie Bolley et al.   LANGMUIR

Physiology of Blood–Brain Interfaces in Relation to Brain Disposition of Small Compounds and Macromolecules

(2013) N. Strazielle et al.   MOLECULAR PHARMACEUTICS

Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis

(2013) Songwen Ju et al.   MOLECULAR THERAPY

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Exosome Secretion Is Enhanced by Invadopodia and Drives Invasive Behavior

(2013) Daisuke Hoshino et al.   Cell Reports

Exosomes as nucleic acid nanocarriers

(2012) Jasper G. van den Boorn et al.   ADVANCED DRUG DELIVERY REVIEWS

Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery

(2012) Ronne Wee Yeh Yeo et al.   ADVANCED DRUG DELIVERY REVIEWS

Tight Junction in Blood-Brain Barrier: An Overview of Structure, Regulation, and Regulator Substances

(2012) Wei-Ye Liu et al.   CNS Neuroscience & Therapeutics

Toward tailored exosomes: The exosomal tetraspanin web contributes to target cell selection

(2012) Sanyukta Rana et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Dynamics of exosome internalization and trafficking

(2012) Tian Tian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

P-selectin-mediated platelet activation promotes adhesion of non-small cell lung carcinoma cells on vascular endothelial cells under flow

(2012) LIANG GONG et al.   Molecular Medicine Reports

Microvesicle-associated AAV Vector as a Novel Gene Delivery System

(2012) Casey A Maguire et al.   MOLECULAR THERAPY

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

(2012) Shin-ichiro Ohno et al.   MOLECULAR THERAPY

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

A strategy of antigen incorporation into exosomes: Comparing cross-presentation levels of antigens delivered by engineered exosomes and by lentiviral virus-like particles

(2012) Laura Lattanzi et al.   VACCINE

Brain microvascular pericytes in health and disease

(2011) Turgay Dalkara et al.   ACTA NEUROPATHOLOGICA

Rab GTPases as regulators of endocytosis, targets of disease and therapeutic opportunities

(2011) JO Agola et al.   CLINICAL GENETICS

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Upregulation of fibronectin and the α5β1 and αvβ3 integrins on blood vessels within the cerebral ischemic penumbra

(2011) Longxuan Li et al.   EXPERIMENTAL NEUROLOGY

The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Protein Suggests a Supramodular Organization of the Membrane-associated Guanylate Kinase (MAGUK) Family Scaffold Protein Core

(2011) Lifeng Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease

(2011) Sudad Saman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Nanochannel electroporation delivers precise amounts of biomolecules into living cells

(2011) Pouyan E. Boukany et al.   Nature Nanotechnology

Effect of Surface Charge of Immortalized Mouse Cerebral Endothelial Cell Monolayer on Transport of Charged Solutes

(2010) Wei Yuan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein

(2010) Keiichi Tamai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell Surface Tetraspanin Tspan8 Contributes to Molecular Pathways of Exosome-Induced Endothelial Cell Activation

(2010) I. Nazarenko et al.   CANCER RESEARCH

A novel interface consisting of homologous immunoglobulin superfamily members with multiple functions

(2010) Zhuwei Xu et al.   Cellular & Molecular Immunology

Delivery of siRNA into breast cancer cells via phage fusion protein-targeted liposomes

(2010) Deepa Bedi et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cellular Internalization of Exosomes Occurs Through Phagocytosis

(2010) Du Feng et al.   TRAFFIC

Click Chemistry and Bioorthogonal Reactions: Unprecedented Selectivity in the Labeling of Biological Molecules

(2009) Michael D. Best   BIOCHEMISTRY

TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways

(2009) Claudio Marcelo Fader et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Molecular insights into  -galactoside  2,6-sialyltransferase secretion in vivo

(2009) S. Kitazume et al.   GLYCOBIOLOGY

Occludin Phosphorylation and Ubiquitination Regulate Tight Junction Trafficking and Vascular Endothelial Growth Factor-induced Permeability

(2009) Tomoaki Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paracrine induction of endothelium by tumor exosomes

(2009) Joshua L Hood et al.   LABORATORY INVESTIGATION

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Defining Macropinocytosis

(2009) Markus C. Kerr et al.   TRAFFIC

The claudins

(2009) Madhu Lal-Nag et al.   GENOME BIOLOGY

Hydrogel nanoparticles in drug delivery

(2008) Mehrdad Hamidi et al.   ADVANCED DRUG DELIVERY REVIEWS

The blood-brain barrier in brain homeostasis and neurological diseases

(2008) Nicolas Weiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Maintaining blood-brain barrier integrity: Pericytes perform better than astrocytes during prolonged oxygen deprivation

(2008) A. Al Ahmad et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Strategies to advance translational research into brain barriers

(2008) Edward Neuwelt et al.   LANCET NEUROLOGY

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5

(2008) Andrea Taddei et al.   NATURE CELL BIOLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Click Chemistry, A Powerful Tool for Pharmaceutical Sciences

(2008) Christopher D. Hein et al.   PHARMACEUTICAL RESEARCH

The development of microgels/nanogels for drug delivery applications

(2008) Jung Kwon Oh et al.   PROGRESS IN POLYMER SCIENCE