Extracellular Vesicles Released by Glioblastoma Cells Stimulate Normal Astrocytes to Acquire a Tumor-Supportive Phenotype Via p53 and MYC Signaling Pathways

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes

(2018) Konrad Gabrusiewicz et al.   OncoImmunology

Glioblastoma multiforme-derived extracellular vesicles drive normal astrocytes towards a tumour-enhancing phenotype

(2017) Soliman Oushy et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy

(2017) Markus Schosserer et al.   Frontiers in Oncology

Rapid Reprogramming of Primary Human Astrocytes into Potent Tumor-Initiating Cells with Defined Genetic Factors

(2016) F. Li et al.   CANCER RESEARCH

p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration

(2016) C Turnquist et al.   CELL DEATH AND DIFFERENTIATION

Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease

(2016) Duthika M. Mallawaaratchy et al.   JOURNAL OF NEURO-ONCOLOGY

Cellular Protrusions - Lamellipodia, Filopodia, Invadopodia and Podosomes - and their Roles in Progression of Orofacial Tumours: Current Understanding

(2015) Kamila Mohamed Om Alblazi et al.   Asian Pacific Journal of Cancer Prevention

Membrane Proteome Analysis of Glioblastoma Cell Invasion

(2015) Duthika M. Mallawaaratchy et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

(2015) Remi-Martin Laberge et al.   NATURE CELL BIOLOGY

Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain

(2015) Kristan E. van der Vos et al.   NEURO-ONCOLOGY

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

FunRich: An open access standalone functional enrichment and interaction network analysis tool

(2015) Mohashin Pathan et al.   PROTEOMICS

Short Hairpin RNA-Mediated Fibronectin Knockdown Delays Tumor Growth in a Mouse Glioma Model

(2015) Sadhak Sengupta et al.   NEOPLASIA

Extracellular vesicles shed by glioma cells: pathogenic role and clinical value

(2014) Dimitry A. Chistiakov et al.   TUMOR BIOLOGY

Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells

(2014) Stacey Watkins et al.   Nature Communications

Exosome in Tumour Microenvironment: Overview of the Crosstalk between Normal and Cancer Cells

(2014) Catarina Roma-Rodrigues et al.   Biomed Research International

Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy

(2014) D Biasoli et al.   Oncogenesis

DJ-1 Associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes

(2013) Kwang Soo Kim et al.   HUMAN MOLECULAR GENETICS

Fibronectin expression in glioblastomas promotes cell cohesion, collective invasion of basement membrane in vitro and orthotopic tumor growth in mice

(2013) E Serres et al.   ONCOGENE

Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development

(2013) P. Kucharzewska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells

(2013) Cheryl CY Li et al.   RNA Biology

Integrin α5β1, the Fibronectin Receptor, as a Pertinent Therapeutic Target in Solid Tumors

(2013) Florence Schaffner et al.   Cancers

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Conditional Astroglial Rictor Overexpression Induces Malignant Glioma in Mice

(2012) Tariq Bashir et al.   PLoS One

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

(2012) Hina Kalra et al.   PLOS BIOLOGY

Emerging Roles of Exosomes in Neuron–Glia Communication

(2012) Carsten Frühbeis et al.   Frontiers in Physiology

Blood platelets contain tumor-derived RNA biomarkers

(2011) R. J. A. Nilsson et al.   BLOOD

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Neuronal-Astrocyte Metabolic Interactions: Understanding the Transition Into Abnormal Astrocytoma Metabolism

(2011) Dennis A. Turner et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Microvesicles and Viral Infection

(2011) D. G. Meckes et al.   JOURNAL OF VIROLOGY

Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis

(2011) Rebecca A. Dragovic et al.   Nanomedicine-Nanotechnology Biology and Medicine

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

(2011) Leonora Balaj et al.   Nature Communications

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

DJ-1 expression in glioblastomas shows positive correlation with p53 expression and negative correlation with epidermal growth factor receptor amplification

(2010) David A. Hinkle et al.   NEUROPATHOLOGY

Selection of suitable housekeeping genes for expression analysis in glioblastoma using quantitative RT-PCR

(2009) Valeria Valente et al.   BMC MOLECULAR BIOLOGY

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens

(2009) Steven M. Pollard et al.   Cell Stem Cell

Myc's other life: stem cells and beyond

(2009) Elisa Laurenti et al.   CURRENT OPINION IN CELL BIOLOGY

Imaging glioma cell invasionin vivoreveals mechanisms of dissemination and peritumoral angiogenesis

(2009) Frank Winkler et al.   GLIA

Glioma-astrocyte interaction modifies the astrocyte phenotype in a co-culture experimental model

(2009) Gagliano   ONCOLOGY REPORTS

Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

(2009) K. Al-Nedawi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S6K1 Plays a Key Role in Glial Transformation

(2008) J. L. Nakamura et al.   CANCER RESEARCH

High Frequency of LMAN1 Abnormalities in Colorectal Tumors with Microsatellite Instability

(2008) N. Roeckel et al.   CANCER RESEARCH

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age

(2008) Steven J. Mullett et al.   NEUROPATHOLOGY

c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

(2008) Jialiang Wang et al.   PLoS One

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE