标题
Exosomes: biogenesis, biologic function and clinical potential
作者
关键词
Exosome, Biogenesis, Biomarker, Therapeutic vehicle
出版物
Cell and Bioscience
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2019-02-15
DOI
10.1186/s13578-019-0282-2
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Separation of plasma-derived exosomes into CD3(+) and CD3(-) fractions allows for association of immune cell and tumour cell markers with disease activity in HNSCC patients
- (2018) M.-N. Theodoraki et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell proliferation
- (2018) Xiangyu Dai et al. Cell Death & Disease
- Human Umbilical Cord MSC-Derived Exosomes Suppress the Development of CCl4-Induced Liver Injury through Antioxidant Effect
- (2018) Wenqian Jiang et al. Stem Cells International
- Exosomes From Adipose-derived Mesenchymal Stem Cells Protect the Myocardium Against Ischemia/Reperfusion Injury Through Wnt/β-Catenin Signaling Pathway
- (2017) Xiaojun Cui et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Next-generation sequencing-based small RNA profiling of cerebrospinal fluid exosomes
- (2017) Yohsuke Yagi et al. NEUROSCIENCE LETTERS
- “Good things come in small packages”: application of exosome-based therapeutics in neonatal lung injury
- (2017) Gareth R Willis et al. PEDIATRIC RESEARCH
- Exosomes in Cancer Nanomedicine and Immunotherapy: Prospects and Challenges
- (2017) Nicholas L. Syn et al. TRENDS IN BIOTECHNOLOGY
- Bone Marrow-Derived Mesenchymal Stem Cells-Derived Exosomes Promote Survival of Retinal Ganglion Cells Through miRNA-Dependent Mechanisms
- (2017) Ben Mead et al. Stem Cells Translational Medicine
- Delivery of Small Interfering RNA to Inhibit Vascular Endothelial Growth Factor in Zebrafish Using Natural Brain Endothelia Cell-Secreted Exosome Nanovesicles for the Treatment of Brain Cancer
- (2016) Tianzhi Yang et al. AAPS Journal
- Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA
- (2016) Le Qu et al. CANCER CELL
- Exosomes in Human Breast Milk Promote EMT
- (2016) W. Qin et al. CLINICAL CANCER RESEARCH
- Exosomes in the Pathology of Neurodegenerative Diseases
- (2016) Jason Howitt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dendritic cell–derived exosomes for cancer therapy
- (2016) Jonathan M. Pitt et al. JOURNAL OF CLINICAL INVESTIGATION
- Plasma exosomes are enriched in Hsp70 and modulated by stress and cortisol in rainbow trout
- (2016) Erin Faught et al. JOURNAL OF ENDOCRINOLOGY
- Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation
- (2016) Cecilia Lässer et al. Journal of Translational Medicine
- Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing
- (2016) Marie-Cécile Didiot et al. MOLECULAR THERAPY
- miR-1246 and miR-4644 in salivary exosome as potential biomarkers for pancreatobiliary tract cancer
- (2016) Tatsuya Machida et al. ONCOLOGY REPORTS
- Tiny Shuttles for Information Transfer: Exosomes in Cardiac Health and Disease
- (2016) Raj Kishore et al. Journal of Cardiovascular Translational Research
- Exosomal cancer immunotherapy is independent of MHC molecules on exosomes
- (2016) Stefanie Hiltbrunner et al. Oncotarget
- Exosomal long noncoding RNA CRNDE-h as a novel serum-based biomarker for diagnosis and prognosis of colorectal cancer
- (2016) Tong Liu et al. Oncotarget
- Exosomes derived from MSCs ameliorate retinal laser injury partially by inhibition of MCP-1
- (2016) Bo Yu et al. Scientific Reports
- MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection
- (2015) Jiajie Sun et al. BMC GENOMICS
- Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis
- (2015) Yan Li et al. CELL RESEARCH
- ESCRTs are everywhere
- (2015) J. H. Hurley EMBO JOURNAL
- MicroRNAs in Salivary Exosome as Potential Biomarkers of Aging
- (2015) Tatsuya Machida et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Exosomes as drug delivery vehicles for Parkinson's disease therapy
- (2015) Matthew J. Haney et al. JOURNAL OF CONTROLLED RELEASE
- Using exosomes, naturally-equipped nanocarriers, for drug delivery
- (2015) Elena V. Batrakova et al. JOURNAL OF CONTROLLED RELEASE
- Exosome isolation: a microfluidic road-map
- (2015) A. Liga et al. LAB ON A CHIP
- Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches
- (2015) Natasa Zarovni et al. METHODS
- Physical characterization and profiling of airway epithelial derived exosomes using light scattering
- (2015) Mehmet Kesimer et al. METHODS
- CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA
- (2015) Alice Conigliaro et al. Molecular Cancer
- Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications
- (2015) Sweta Rani et al. MOLECULAR THERAPY
- Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio
- (2015) Tianzhi Yang et al. PHARMACEUTICAL RESEARCH
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Exosomes and their roles in immune regulation and cancer
- (2015) David W. Greening et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes
- (2015) Valentina R. Minciacchi et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- HucMSC-Exosome Mediated-Wnt4 Signaling Is Required for Cutaneous Wound Healing
- (2015) Bin Zhang et al. STEM CELLS
- Exosomes in human semen restrict HIV-1 transmission by vaginal cells and block intravaginal replication of LP-BM5 murine AIDS virus complex
- (2015) Marisa N. Madison et al. VIROLOGY
- Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC
- (2015) Benjamin Besse et al. OncoImmunology
- Label-Free Quantitative Detection of Tumor-Derived Exosomes through Surface Plasmon Resonance Imaging
- (2014) Ling Zhu et al. ANALYTICAL CHEMISTRY
- Determination of Exosome Concentration in Solution Using Surface Plasmon Resonance Spectroscopy
- (2014) Déborah L. M. Rupert et al. ANALYTICAL CHEMISTRY
- Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration
- (2014) Keisuke Shimbo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Microvesicles and exosomes for intracardiac communication
- (2014) Joost P.G. Sluijter et al. CARDIOVASCULAR RESEARCH
- Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction
- (2014) L. Barile et al. CARDIOVASCULAR RESEARCH
- Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes
- (2014) Ugur Gezer et al. CELL BIOLOGY INTERNATIONAL
- Exosomes and Microvesicles: Identification and Targeting By Particle Size and Lipid Chemical Probes
- (2014) Noah Kastelowitz et al. CHEMBIOCHEM
- Role of Exosomes in Myocardial Remodeling
- (2014) Anders Waldenström et al. CIRCULATION RESEARCH
- Exosomes
- (2014) Derek M. Yellon et al. CIRCULATION RESEARCH
- Microvesicles as Cell–Cell Messengers in Cardiovascular Diseases
- (2014) Xavier Loyer et al. CIRCULATION RESEARCH
- Expression of B-Cell Surface Antigens in Subpopulations of Exosomes Released From B-Cell Lymphoma Cells
- (2014) Morten P. Oksvold et al. CLINICAL THERAPEUTICS
- Exosomes as Immunotheranostic Nanoparticles
- (2014) Natasha G et al. CLINICAL THERAPEUTICS
- MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells
- (2014) Isobel S. Okoye et al. IMMUNITY
- Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery
- (2014) Luisa Pascucci et al. JOURNAL OF CONTROLLED RELEASE
- Human Saliva-Derived Exosomes
- (2014) Ayelet Zlotogorski-Hurvitz et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Isolation of biologically-active exosomes from human plasma
- (2014) Laurent Muller et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Exosomal miRNAs as potential biomarkers of cardiovascular risk in children
- (2014) Abdelnaby Khalyfa et al. Journal of Translational Medicine
- Curcumin-primed exosomes mitigate endothelial cell dysfunction during hyperhomocysteinemia
- (2014) A. Kalani et al. LIFE SCIENCES
- Proteomics of extracellular vesicles: Exosomes and ectosomes
- (2014) Dong-Sic Choi et al. MASS SPECTROMETRY REVIEWS
- Intercellular communication by exosomes in placenta: A possible role in cell fusion?
- (2014) M. Record PLACENTA
- GDNF-Transfected Macrophages Produce Potent Neuroprotective Effects in Parkinson's Disease Mouse Model
- (2014) Yuling Zhao et al. PLoS One
- Ceramide: A simple sphingolipid with unique biophysical properties
- (2014) Bruno M. Castro et al. PROGRESS IN LIPID RESEARCH
- Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
- (2014) Lahiru Gangoda et al. PROTEOMICS
- Sorting it out: Regulation of exosome loading
- (2014) Carolina Villarroya-Beltri et al. SEMINARS IN CANCER BIOLOGY
- Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models
- (2014) Cheau Tan et al. Stem Cell Research & Therapy
- Expression of Serum Exosomal MicroRNA-21 in Human Hepatocellular Carcinoma
- (2014) Hongwei Wang et al. Biomed Research International
- Exosomes: A Potential Key Target in Cardio-Renal Syndrome
- (2014) Laura Gonzalez-Calero et al. Frontiers in Immunology
- Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors
- (2013) Su Chul Jang et al. ACS Nano
- Role of stem-cell-derived microvesicles in the paracrine action of stem cells: Figure 1
- (2013) Giovanni Camussi et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies
- (2013) Michel Record et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Emerging concepts on the role of exosomes in lipid metabolic diseases
- (2013) Michel Record et al. BIOCHIMIE
- A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
- (2013) Yanhua Tian et al. BIOMATERIALS
- Characterization of human plasma-derived exosomal RNAs by deep sequencing
- (2013) Xiaoyi Huang et al. BMC GENOMICS
- MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease
- (2013) Maarten Hulsmans et al. CARDIOVASCULAR RESEARCH
- CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+T cells contributes to their regulatory function
- (2013) Lesley Ann Smyth et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes
- (2013) Daniel Perez-Hernandez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats
- (2013) Hongqi Xin et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Dendritic Cell-Derived Exosomes Need To Activate Both T and B Cells To Induce Antitumor Immunity
- (2013) T. I. Naslund et al. JOURNAL OF IMMUNOLOGY
- Quantification of human urinary exosomes by nanoparticle tracking analysis
- (2013) Wilna Oosthuyzen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
- (2013) Marco Prunotto et al. Journal of Proteomics
- Prostate Cancer Biomarker Profiles in Urinary Sediments and Exosomes
- (2013) Siebren Dijkstra et al. JOURNAL OF UROLOGY
- Specific Transfection of Inflamed Brain by Macrophages: A New Therapeutic Strategy for Neurodegenerative Diseases
- (2013) Matthew J. Haney et al. PLoS One
- Exosomes as nucleic acid nanocarriers
- (2012) Jasper G. van den Boorn et al. ADVANCED DRUG DELIVERY REVIEWS
- Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials
- (2012) Alexander V. Vlassov et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma
- (2012) Youhei Tanaka et al. CANCER
- Anticancer Drugs Cause Release of Exosomes with Heat Shock Proteins from Human Hepatocellular Carcinoma Cells That Elicit Effective Natural Killer Cell Antitumor Responsesin Vitro
- (2012) Li-Hong Lv et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Microvesicle-associated AAV Vector as a Novel Gene Delivery System
- (2012) Casey A Maguire et al. MOLECULAR THERAPY
- Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells
- (2012) Shin-ichiro Ohno et al. MOLECULAR THERAPY
- Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes
- (2012) Jessica Wahlgren et al. NUCLEIC ACIDS RESEARCH
- Cardiomyocyte Microvesicles Contain DNA/RNA and Convey Biological Messages to Target Cells
- (2012) Anders Waldenström et al. PLoS One
- Human Embryonic Mesenchymal Stem Cell-Derived Conditioned Medium Rescues Kidney Function in Rats with Established Chronic Kidney Disease
- (2012) Arianne van Koppen et al. PLoS One
- Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth
- (2012) Hongqi Xin et al. STEM CELLS
- CD4+ T cell-released exosomes inhibit CD8+ cytotoxic T-lymphocyte responses and antitumor immunity
- (2011) Haifeng Zhang et al. Cellular & Molecular Immunology
- Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles
- (2011) Bence György et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands
- (2011) Philippe de Medina et al. CHEMISTRY AND PHYSICS OF LIPIDS
- The ESCRT Pathway
- (2011) William M. Henne et al. DEVELOPMENTAL CELL
- Microautophagy of Cytosolic Proteins by Late Endosomes
- (2011) Ranjit Sahu et al. DEVELOPMENTAL CELL
- Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production
- (2011) A. Clayton et al. JOURNAL OF IMMUNOLOGY
- Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain
- (2011) Xiaoying Zhuang et al. MOLECULAR THERAPY
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- ExoCarta 2012: database of exosomal proteins, RNA and lipids
- (2011) S. Mathivanan et al. NUCLEIC ACIDS RESEARCH
- Regulation of the MVB Pathway by SCAMP3
- (2011) Thomas Falguières et al. TRAFFIC
- Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses
- (2011) Angélique Bobrie et al. TRAFFIC
- Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
- (2011) María Mittelbrunn et al. Nature Communications
- Transfer of the glycosylphosphatidylinositol-anchored 5′-nucleotidase CD73 from adiposomes into rat adipocytes stimulates lipid synthesis
- (2010) G Müller et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation
- (2010) J. Webber et al. CANCER RESEARCH
- Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration
- (2010) Julia Esser et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy
- (2010) Tian Tian et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins
- (2010) Caroline Subra et al. JOURNAL OF LIPID RESEARCH
- Exosomes/microvesicles as a mechanism of cell-to-cell communication
- (2010) Giovanni Camussi et al. KIDNEY INTERNATIONAL
- Exosomes in the ascites of ovarian cancer patients: origin and effects on anti-tumor immunity
- (2010) Keng ONCOLOGY REPORTS
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
- (2010) Ruenn Chai Lai et al. Stem Cell Research
- Exosomes – vesicular carriers for intercellular communication
- (2009) Mikael Simons et al. CURRENT OPINION IN CELL BIOLOGY
- Exosomes: proteomic insights and diagnostic potential
- (2009) Richard J Simpson et al. Expert Review of Proteomics
- Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses
- (2008) I. S. Zeelenberg et al. CANCER RESEARCH
- Urinary exosomal transcription factors, a new class of biomarkers for renal disease
- (2008) Hua Zhou et al. KIDNEY INTERNATIONAL
- Proteomic profiling of exosomes: Current perspectives
- (2008) Richard J. Simpson et al. PROTEOMICS
- Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
- (2008) K. Trajkovic et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now