Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli

Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease

(2017) Shashi Bala et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles

(2016) Sriram Balusu et al.   EMBO Molecular Medicine

AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB

(2016) Noah I. Hornick et al.   Science Signaling

The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting

(2016) Laura Santangelo et al.   Cell Reports

AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB

(2016) Noah I. Hornick et al.   Science Signaling

Profiling peripheral microRNAs in obesity and type 2 diabetes mellitus

(2015) Liangping Wu et al.   APMIS

Noncoding RNAs and chronic inflammation: Micro-managing the fire within

(2015) Margaret Alexander et al.   BIOESSAYS

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

(2015) Margaret Alexander et al.   Nature Communications

Rab27A Regulates Transport of Cell Surface Receptors Modulating Multinucleation and Lysosome-Related Organelles in Osteoclasts

(2015) Megumi Shimada-Sugawara et al.   Scientific Reports

A role for Rab27 in neutrophil chemotaxis and lung recruitment

(2014) Rajesh K Singh et al.   BMC CELL BIOLOGY

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

(2014) Isobel S. Okoye et al.   IMMUNITY

miR-155 Promotes T Follicular Helper Cell Accumulation during Chronic, Low-Grade Inflammation

(2014) Ruozhen Hu et al.   IMMUNITY

Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease

(2013) M. Iborra et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

(2013) Jianhua Li et al.   NATURE IMMUNOLOGY

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases

(2012) Shashi Bala et al.   HEPATOLOGY

Intercellular communication: diverse structures for exchange of genetic information

(2012) Maria Mittelbrunn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Increased Survival and Reduced Neutrophil Infiltration of the Liver in Rab27a- but Not Munc13-4-Deficient Mice in Lipopolysaccharide-Induced Systemic Inflammation

(2011) Jennifer L. Johnson et al.   INFECTION AND IMMUNITY

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Horizontal transfer of RNAs: exosomes as mediators of intercellular communication

(2011) Saraswathi Ramachandran et al.   Wiley Interdisciplinary Reviews-RNA

Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease

(2010) Shashi Bala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY

Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα

(2009) Sophie Viaud et al.   PLoS One

Inositol phosphatase SHIP1 is a primary target of miR-155

(2009) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab27a and Rab27b Regulate Neutrophil Azurophilic Granule Exocytosis and NADPH oxidase Activity by Independent Mechanisms

(2009) Jennifer L. Johnson et al.   TRAFFIC

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

(2008) I. S. Zeelenberg et al.   CANCER RESEARCH

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY