Targeting RGD-binding integrins as an integrative therapy for diabetic retinopathy and neovascular age-related macular degeneration
出版年份 2021 全文链接
标题
Targeting RGD-binding integrins as an integrative therapy for diabetic retinopathy and neovascular age-related macular degeneration
作者
关键词
RGD-binding integrin, Diabetic retinopathy, Neovascular age-related macular degeneration, Retina
出版物
PROGRESS IN RETINAL AND EYE RESEARCH
Volume -, Issue -, Pages 100966
出版商
Elsevier BV
发表日期
2021-03-27
DOI
10.1016/j.preteyeres.2021.100966
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics
- (2020) Tejasvi Dudiki et al. Nature Communications
- Do Genomic Factors Play a Role in Diabetic Retinopathy?
- (2020) Andrea P. Cabrera et al. Journal of Clinical Medicine
- Risuteganib—a novel integrin inhibitor for the treatment of non-exudative (dry) age-related macular degeneration and diabetic macular edema
- (2020) Lincoln T. Shaw et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS
- (2020) Zhilin Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Single-cell transcriptome analysis of the Akimba mouse retina reveals cell-type-specific insights into the pathobiology of diabetic retinopathy
- (2020) Inge Van Hove et al. DIABETOLOGIA
- The retinal tyrosine kinome of diabetic Akimba mice highlights potential for specific Src family kinase inhibition in retinal vascular disease
- (2020) Jurgen Sergeys et al. EXPERIMENTAL EYE RESEARCH
- Anti-Integrin therapy for retinovascular diseases
- (2020) Ashay D. Bhatwadekar et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Suppression of Ocular Vascular Inflammation through Peptide-Mediated Activation of Angiopoietin-Tie2 Signaling
- (2020) Adam C. Mirando et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Members of the Highly Diverse Crassostrea gigas Integrin Family Cooperate for the Generation of Various Immune Responses
- (2020) Zhao Lv et al. Frontiers in Immunology
- Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2
- (2020) Elvira Agrón et al. OPHTHALMOLOGY
- Revisiting the role of factor H in age-related macular degeneration: Insights from complement-mediated renal disease and rare genetic variants
- (2020) Nikolaos Tzoumas et al. SURVEY OF OPHTHALMOLOGY
- Recombinant RGD-disintegrin DisBa-01 blocks integrin αvβ3 and impairs VEGF signaling in endothelial cells
- (2019) Taís M. Danilucci et al. Cell Communication and Signaling
- VEGF in Signaling and Disease: Beyond Discovery and Development
- (2019) Rajendra S. Apte et al. CELL
- Role of Angiopoietin-2 in Vascular Physiology and Pathophysiology
- (2019) Racheal G. Akwii et al. Cells
- Integrin αvβ6 mediates epithelial-mesenchymal transition in human bronchial epithelial cells induced by lipopolysaccharides of Pseudomonas aeruginosa via TGF-β1-Smad2/3 signaling pathway
- (2019) Weiming Liu et al. FOLIA MICROBIOLOGICA
- The Role of Genetic Variants (rs869109213 and rs2070744) Of the eNOS Gene and BglII in the α2 Subunit of the α2β1 Integrin Gene in Diabetic Retinopathy in a Tunisian Population
- (2019) Fatma Midani et al. Seminars in Ophthalmology
- Tellurium Compounds Prevent and Reverse Type-1 Diabetes in NOD Mice by Modulating α4β7 Integrin Activity, IL-1β, and T Regulatory Cells
- (2019) Tom Eitan Yossipof et al. Frontiers in Immunology
- Overexpression of α5β1 integrin and angiopoietin-1 co-operatively promote blood-brain barrier integrity and angiogenesis following ischemic stroke
- (2019) Lu Wang et al. EXPERIMENTAL NEUROLOGY
- Higher matrix stiffness as an independent initiator triggers epithelial-mesenchymal transition and facilitates HCC metastasis
- (2019) Yinying Dong et al. Journal of Hematology & Oncology
- Age-related macular degeneration: A two-level model hypothesis
- (2019) Maarten P. Rozing et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Non-canonical (non-SMAD2/3) TGF-β signaling in fibrosis: Mechanisms and targets
- (2019) Kenneth W. Finnson et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- SNAI1, an endothelial–mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization
- (2018) Jia-Xing Sun et al. ANGIOGENESIS
- Distinct CD40L receptors mediate inflammasome activation and secretion of IL-1β and MCP-1 in cultured human retinal pigment epithelial cells
- (2018) Zong-Mei Bian et al. EXPERIMENTAL EYE RESEARCH
- Inhibition of integrin α5β1 ameliorates VEGF-induced retinal neovascularization and leakage by suppressing NLRP3 inflammasome signaling in a mouse model
- (2018) Ailing Sui et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Beyond the Matrix: The Many Non-ECM Ligands for Integrins
- (2018) Bryce LaFoya et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2
- (2018) Chloe Peach et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ocular Distribution and Pharmacodynamics of SF0166, a Topically Administeredαvβ3Integrin Antagonist, for the Treatment of Retinal Diseases
- (2018) Ben C. Askew et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Targeting β1-integrin inhibits vascular leakage in endotoxemia
- (2018) Laura Hakanpaa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrin β3 Mediates the Endothelial-to-Mesenchymal Transition via the Notch Pathway
- (2018) Weisen Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
- (2018) Shyam S. Chaurasia et al. Scientific Reports
- Roles of integrins and extracellular matrix in stroke
- (2018) Danielle Edwards et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Comparison of Surgically Excised Premacular Membranes in Eyes with Macular Pucker and Proliferative Vitreoretinopathy
- (2018) Stefanie R. Guenther et al. CURRENT EYE RESEARCH
- IL-1β promotes transendothelial migration of PBMCs by upregulation of the FN/α5β1 signalling pathway in immortalised human brain microvascular endothelial cells
- (2018) Josephine Labus et al. EXPERIMENTAL CELL RESEARCH
- Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction
- (2018) Seung-Jun Lee et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases
- (2018) Tine Van Bergen et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Myofibroblasts in macular fibrosis secondary to neovascular age-related macular degeneration - the potential sources and molecular cues for their recruitment and activation
- (2018) Karis Little et al. EBioMedicine
- Initiation of fibrosis in the integrin Αvβ6 knockout mice
- (2018) Wenjing Wu et al. EXPERIMENTAL EYE RESEARCH
- The potent small molecule integrin antagonist THR-687 is a promising next-generation therapy for retinal vascular disorders
- (2018) Tjing-Tjing Hu et al. EXPERIMENTAL EYE RESEARCH
- The role of integrins in glaucoma
- (2017) Mark S. Filla et al. EXPERIMENTAL EYE RESEARCH
- Lebecetin, a C-type lectin, inhibits choroidal and retinal neovascularization
- (2017) Fadoua Montassar et al. FASEB JOURNAL
- Direct binding to integrins and loss of disulfide linkage in interleukin-1β (IL-1β) are involved in the agonistic action of IL-1β
- (2017) Yoko K. Takada et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Talin – the master of integrin adhesions
- (2017) Benjamin Klapholz et al. JOURNAL OF CELL SCIENCE
- αVβ3 Integrin regulates astrocyte reactivity
- (2017) Raúl Lagos-Cabré et al. Journal of Neuroinflammation
- Therapeutic targeting of the angiopoietin–TIE pathway
- (2017) Pipsa Saharinen et al. NATURE REVIEWS DRUG DISCOVERY
- High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation
- (2017) Nathalie Thorin-Trescases et al. Oxidative Medicine and Cellular Longevity
- Mechanotransduction of matrix stiffness in regulation of focal adhesion size and number: reciprocal regulation of caveolin-1 and β1 integrin
- (2017) Yi-Chun Yeh et al. Scientific Reports
- Early and intermediate age-related macular degeneration: update and clinical review
- (2017) Alfredo Garcia-Layana et al. Clinical Interventions in Aging
- Extracellular matrix structure
- (2016) Achilleas D. Theocharis et al. ADVANCED DRUG DELIVERY REVIEWS
- Retinal Ganglion Cell Layer Change in Patients Treated With Anti–Vascular Endothelial Growth Factor for Neovascular Age-related Macular Degeneration
- (2016) Marco Beck et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Tat PTD-Endostatin-RGD: A novel protein with anti-angiogenesis effect in retina via eye drops
- (2016) Yan Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- αv integrins: key regulators of tissue fibrosis
- (2016) Kylie P. Conroy et al. CELL AND TISSUE RESEARCH
- Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems
- (2016) L. Eklund et al. CLINICAL SCIENCE
- Minireview: Fibronectin in retinal disease
- (2016) Charles G Miller et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Retinal fibrosis in diabetic retinopathy
- (2016) Sayon Roy et al. EXPERIMENTAL EYE RESEARCH
- Molecular mechanisms of subretinal fibrosis in age-related macular degeneration
- (2016) Keijiro Ishikawa et al. EXPERIMENTAL EYE RESEARCH
- Current and investigational drugs for the treatment of diabetic retinopathy
- (2016) Michael Steven Tolentino et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Risk of geographic atrophy in age-related macular degeneration patients treated with intravitreal anti-VEGF agents
- (2016) M Gemenetzi et al. EYE
- Angiopoietin-like Protein 2 Is a Multistep Regulator of Inflammatory Neovascularization in a Murine Model of Age-related Macular Degeneration
- (2016) Manabu Hirasawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mice deficient in endothelial α5 integrin are profoundly resistant to experimental ischemic stroke
- (2016) Jill Roberts et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis
- (2016) Robert Hennig et al. JOURNAL OF DRUG TARGETING
- ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2
- (2016) Elisa Gomez Perdiguero et al. JOURNAL OF PATHOLOGY
- Quantitative Proteomics Reveals β2 Integrin-mediated Cytoskeletal Rearrangement in Vascular Endothelial Growth Factor (VEGF)-induced Retinal Vascular Hyperpermeability
- (2016) Dong Hyun Jo et al. MOLECULAR & CELLULAR PROTEOMICS
- Candidate gene studies of diabetic retinopathy in human
- (2016) Petra Priščáková et al. MOLECULAR BIOLOGY REPORTS
- Joint Antiangiogenic Effect of ATN-161 and Anti-VEGF Antibody in a Rat Model of Early Wet Age-Related Macular Degeneration
- (2016) Wen-Qiu Wang et al. MOLECULAR PHARMACEUTICS
- Mechanisms and regulation of endothelial VEGF receptor signalling
- (2016) Michael Simons et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The progress in understanding and treatment of diabetic retinopathy
- (2016) Alan W. Stitt et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Angiopoietin 2 induces astrocyte apoptosis via αvβ5-integrin signaling in diabetic retinopathy
- (2016) J-H Yun et al. Cell Death & Disease
- Research advances on structure and biological functions of integrins
- (2016) Li Pan et al. SpringerPlus
- Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin
- (2016) Annamarie C. Dalton et al. PLoS One
- Angiopoietin-like protein 2 induces proinflammatory responses in peritoneal cells
- (2015) Masato Umikawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effects of IGFBP-1 and IGFBP-2 and their fragments on migration and IGF-induced proliferation of human dermal fibroblasts
- (2015) Katrin Brandt et al. GROWTH HORMONE & IGF RESEARCH
- The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions
- (2015) H. E. Balcioglu et al. JOURNAL OF CELL SCIENCE
- Insulin-Like Growth Factor Binding Protein-2 Promotes Adhesion of Endothelial Progenitor Cells to Endothelial Cells via Integrin α5β1
- (2015) Nianping Feng et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Interactions of DPP-4 and integrin β1 influences endothelial-to-mesenchymal transition
- (2015) Sen Shi et al. KIDNEY INTERNATIONAL
- The Proteome of Native Adult Müller Glial Cells From Murine Retina
- (2015) Antje Grosche et al. MOLECULAR & CELLULAR PROTEOMICS
- Leukocyte integrins: Role in leukocyte recruitment and as therapeutic targets in inflammatory disease
- (2015) Ioannis Mitroulis et al. PHARMACOLOGY & THERAPEUTICS
- αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
- (2015) Murilo F. Roggia et al. PLoS One
- The α v β 1 integrin plays a critical in vivo role in tissue fibrosis
- (2015) Nilgun I. Reed et al. Science Translational Medicine
- RGD Peptides Protects Against Acute Lung Injury in Septic Mice Through Wisp1-Integrin β6 Pathway Inhibition
- (2015) Xibing Ding et al. SHOCK
- High prevalence of diabetic retinopathy and lack of association with integrin α2 gene polymorphisms in patients with type 2 diabetes from Northeastern Mexico
- (2015) ANA CECILIA CEPEDA-NIETO et al. Experimental and Therapeutic Medicine
- Integrin β1 controls VE-cadherin localization and blood vessel stability
- (2015) Hiroyuki Yamamoto et al. Nature Communications
- Endothelial destabilization by angiopoietin-2 via integrin β1 activation
- (2015) Laura Hakanpaa et al. Nature Communications
- Future Therapies of Wet Age-Related Macular Degeneration
- (2015) Makoto Ishikawa et al. Journal of Ophthalmology
- Influence of Extracellular Matrix Components on the Expression of Integrins and Regeneration of Adult Retinal Ganglion Cells
- (2015) Elena Vecino et al. PLoS One
- Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells
- (2015) Keren Cohen et al. Oncotarget
- Integrin-directed modulation of macrophage responses to biomaterials
- (2014) Toral D. Zaveri et al. BIOMATERIALS
- Association of Platelet Glycoprotein Receptor Alpha2beta1 Integrin and Glycoprotein IIIa Gene Polymorphisms with Diabetic Retinopathy: Evidence from 3007 Subjects
- (2014) Jian-Yang Gong et al. CURRENT EYE RESEARCH
- Angiopoietin 2 Induces Pericyte Apoptosis via 3 1 Integrin Signaling in Diabetic Retinopathy
- (2014) S. W. Park et al. DIABETES
- Therapeutic efficacy of a novel non-peptide αvβ3 integrin antagonist for pathological retinal angiogenesis in mice
- (2014) Yong-Jie Li et al. EXPERIMENTAL EYE RESEARCH
- Gln-362 of Angiopoietin-2 Mediates Migration of Tumor and Endothelial Cells through Association with α5β1 Integrin
- (2014) Hyo Seon Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co-regulate axonal outgrowth of mouse retinal ganglion cells
- (2014) Djoere Gaublomme et al. JOURNAL OF NEUROCHEMISTRY
- Dual Targeting of Integrin v 3 and Matrix Metalloproteinase-2 for Optical Imaging of Tumors and Chemotherapeutic Delivery
- (2014) J. L. Crisp et al. MOLECULAR CANCER THERAPEUTICS
- Osteopontin Is Induced by TGF-β2 and Regulates Metabolic Cell Activity in Cultured Human Optic Nerve Head Astrocytes
- (2014) Carolin Neumann et al. PLoS One
- Cyr61 induces the expression of monocyte chemoattractant protein-1 via the integrin ανβ3, FAK, PI3K/Akt, and NF-κB pathways in retinal vascular endothelial cells
- (2013) Jian-Jang You et al. CELLULAR SIGNALLING
- Advances in our understanding of diabetic retinopathy
- (2013) Alan W. Stitt et al. CLINICAL SCIENCE
- Effective Treatment of Mouse Sepsis With an Inhibitory Antibody Targeting Integrin αvβ5*
- (2013) George Su et al. CRITICAL CARE MEDICINE
- CCN2 promotes keratinocyte adhesion and migration via integrin α5β1
- (2013) Elizabeth Kiwanuka et al. EXPERIMENTAL CELL RESEARCH
- Increased Activation of Latent TGF-β1 by αVβ3 in Human Crohnʼs Disease and Fibrosis in TNBS Colitis Can Be Prevented by Cilengitide
- (2013) Chao Li et al. INFLAMMATORY BOWEL DISEASES
- Proteolytic Processing Regulates Placental Growth Factor Activities
- (2013) Daniel C. Hoffmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TNF-α promotes cerebral pericyte remodeling in vitro, via a switch from α1 to α2 integrins
- (2013) Ulrich Tigges et al. Journal of Neuroinflammation
- Signalling pathways linking integrins with cell cycle progression
- (2013) Paulina Moreno-Layseca et al. MATRIX BIOLOGY
- A Urokinase Receptor-Derived Peptide Inhibiting VEGF-Dependent Directional Migration and Vascular Sprouting
- (2013) K. Bifulco et al. MOLECULAR CANCER THERAPEUTICS
- Integrin inactivators: balancing cellular functions in vitro and in vivo
- (2013) Daniel Bouvard et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Tellurium Compound AS101 Ameliorates Experimental Autoimmune Encephalomyelitis by VLA-4 Inhibition and Suppression of Monocyte and T Cell Infiltration into the CNS
- (2013) Jun-Ho Lee et al. NEUROMOLECULAR MEDICINE
- Clinical Classification of Age-related Macular Degeneration
- (2013) Frederick L. Ferris et al. OPHTHALMOLOGY
- Risk of Scar in the Comparison of Age-related Macular Degeneration Treatments Trials
- (2013) Ebenezer Daniel et al. OPHTHALMOLOGY
- Angiopoietin-1 Guides Directional Angiogenesis Through Integrin v 5 Signaling for Recovery of Ischemic Retinopathy
- (2013) J. Lee et al. Science Translational Medicine
- uPAR
- (2013) Pavel Uhrin et al. Cell Adhesion & Migration
- Current treatments in diabetic macular oedema: systematic review and meta-analysis
- (2013) John Alexander Ford et al. BMJ Open
- Vascular Hyperpermeability, Angiogenesis, and Stroma Generation
- (2013) J. A. Nagy et al. Cold Spring Harbor Perspectives in Medicine
- Integrin Activation States and Eosinophil Recruitment in Asthma
- (2013) Mats W. Johansson et al. Frontiers in Pharmacology
- Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration
- (2012) E. Rossi et al. BLOOD
- VEGF-induced endothelial cell migration requires urokinase receptor (uPAR)-dependent integrin redistribution
- (2012) Revu Ann Alexander et al. CARDIOVASCULAR RESEARCH
- DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
- (2012) Valeria Tarallo et al. CELL
- Integrin α5β1 Activates the NLRP3 Inflammasome by Direct Interaction with a Bacterial Surface Protein
- (2012) Hye-Kyoung Jun et al. IMMUNITY
- N-acetylglucosaminyltransferase V negatively regulates integrin α5β1-mediated monocyte adhesion and transmigration through vascular endothelium
- (2012) HUO-MEI YANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling
- (2012) Moritz Felcht et al. JOURNAL OF CLINICAL INVESTIGATION
- Defective Retinal Vascular Endothelial Cell Development As a Consequence of Impaired Integrin V 8-Mediated Activation of Transforming Growth Factor-
- (2012) T. D. Arnold et al. JOURNAL OF NEUROSCIENCE
- Angiopoietin-like protein 2 mediates endotoxin-induced acute inflammation in the eye
- (2012) Atsuhiro Kanda et al. LABORATORY INVESTIGATION
- Age-related macular degeneration
- (2012) Laurence S Lim et al. LANCET
- Mechanisms of Age-Related Macular Degeneration
- (2012) Jayakrishna Ambati et al. NEURON
- Ranibizumab for Diabetic Macular Edema
- (2012) Quan Dong Nguyen et al. OPHTHALMOLOGY
- Integrins as receptor targets for neurological disorders
- (2012) Xin Wu et al. PHARMACOLOGY & THERAPEUTICS
- β1 Integrin-Focal Adhesion Kinase (FAK) Signaling Modulates Retinal Ganglion Cell (RGC) Survival
- (2012) Andrea Rachelle C. Santos et al. PLoS One
- Pericyte-endothelial cell interaction
- (2012) Sharmila Chatterjee et al. Cell Adhesion & Migration
- Absence of Integrin αvβ3 Enhances Vascular Leak in Mice by Inhibiting Endothelial Cortical Actin Formation
- (2011) George Su et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Potentiation of Platelet-Derived Growth Factor Receptor-β Signaling Mediated by Integrin-Associated MFG-E8
- (2011) Sei-ichiro Motegi et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane
- (2011) L. Scheppke et al. BLOOD
- Angiopoietin-like Protein 2 Is an Important Facilitator of Inflammatory Carcinogenesis and Metastasis
- (2011) J. Aoi et al. CANCER RESEARCH
- Retinal Pigment Epithelium Cell Alignment on Nanostructured Collagen Matrices
- (2011) Stefan Ulbrich et al. CELLS TISSUES ORGANS
- αVβ3-integrin expression through ERK activation mediates cell attachment and is necessary for production of tumor necrosis factor alpha in monocytic THP-1 cells stimulated by phorbol myristate acetate
- (2011) Yuichi Kurihara et al. CELLULAR IMMUNOLOGY
- The astrocyte-expressed integrin v 8 governs blood vessel sprouting in the developing retina
- (2011) S. Hirota et al. DEVELOPMENT
- Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis
- (2011) D. Stenzel et al. DEVELOPMENT
- Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac)
- (2011) Takeshi Yoshida et al. EXPERIMENTAL EYE RESEARCH
- Roles of αvβ5, FAK and MerTK in oxidative stress inhibition of RPE cell phagocytosis
- (2011) Suofu Qin et al. EXPERIMENTAL EYE RESEARCH
- TGF-β signaling in fibrosis
- (2011) Anna Biernacka et al. GROWTH FACTORS
- Evidence of association ofAPOEwith age-related macular degeneration - a pooled analysis of 15 studies
- (2011) Gareth J. McKay et al. HUMAN MUTATION
- Müller Glial Cells in Retinal Disease
- (2011) Andreas Bringmann et al. OPHTHALMOLOGICA
- Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina
- (2011) Bhanu Dasari et al. BMC Ophthalmology
- Endothelial 1 integrins regulate sprouting and network formation during vascular development
- (2010) D. Malan et al. DEVELOPMENT
- Diabetic Retinopathy: Targeting Vasoregression
- (2010) H.-P. Hammes et al. DIABETES
- Angiopoietin-2 Stimulation of Endothelial Cells Induces αvβ3 Integrin Internalization and Degradation
- (2010) Markus Thomas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Involvement of β1-Integrin Up-regulation in Basic Fibroblast Growth Factor- and Epidermal Growth Factor-induced Proliferation of Mouse Neuroepithelial Cells
- (2010) Yusuke Suzuki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- αVβ3 integrin regulates macrophage inflammatory responses via PI3 kinase/Akt-dependent NF-κB activation
- (2010) Alexander S. Antonov et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Improvements in endotoxemic syndromes using a disintegrin, rhodostomin, through integrin αvβ3-dependent pathway
- (2010) C.-C. HSU et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Turning Müller Glia into Neural Progenitors in the Retina
- (2010) Andy J. Fischer et al. MOLECULAR NEUROBIOLOGY
- Two-Year Outcomes of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) Study
- (2010) Quan Dong Nguyen et al. OPHTHALMOLOGY
- Vascular Cellular Adhesion Molecule-1 (VCAM-1) Expression in Mice Retinal Vessels Is Affected by Both Hyperglycemia and Hyperlipidemia
- (2010) Carin Gustavsson et al. PLoS One
- Transforming Growth Factor-β Upregulates the Expression of Integrin and Related Proteins in MRC-5 Human Myofibroblasts
- (2010) Eiko Honda et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Cooperation between integrin ανβ3 and VEGFR2 in angiogenesis
- (2009) Payaningal R. Somanath et al. ANGIOGENESIS
- Single and combined effects of αvβ3- and α5β1-integrins on capillary tube formation in a human fibrinous matrix
- (2009) Nancy Laurens et al. ANGIOGENESIS
- Preclinical Evaluation of the Novel Small-Molecule Integrin α5β1 Inhibitor JSM6427 in Monkey and Rabbit Models of Choroidal Neovascularization
- (2009) Grit Zahn ARCHIVES OF OPHTHALMOLOGY
- Angiopoietin-like Protein 2 Promotes Chronic Adipose Tissue Inflammation and Obesity-Related Systemic Insulin Resistance
- (2009) Mitsuhisa Tabata et al. Cell Metabolism
- Microvascular lesions of diabetic retinopathy: clues towards understanding pathogenesis?
- (2009) T M Curtis et al. EYE
- Conditional deletion of β1-integrin in astroglia causes partial reactive gliosis
- (2009) Stefanie Robel et al. GLIA
- Nanoparticle–integrin antagonist C16Y peptide treatment of choroidal neovascularization in rats
- (2009) Hyuncheol Kim et al. JOURNAL OF CONTROLLED RELEASE
- The Integrin Antagonist Cilengitide Activates αVβ3, Disrupts VE-Cadherin Localization at Cell Junctions and Enhances Permeability in Endothelial Cells
- (2009) Gian Carlo Alghisi et al. PLoS One
- Cellular signaling and factors involved in Müller cell gliosis: Neuroprotective and detrimental effects
- (2009) Andreas Bringmann et al. PROGRESS IN RETINAL AND EYE RESEARCH
- The Tail of Integrins, Talin, and Kindlins
- (2009) M. Moser et al. SCIENCE
- Feedback Mechanism Between Blood Vessels and Astrocytes in Retinal Vascular development
- (2009) Yoshiaki Kubota et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Molecular dissection of reactive astrogliosis and glial scar formation
- (2009) Michael V. Sofroniew TRENDS IN NEUROSCIENCES
- Integrins
- (2008) Rita Silva et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Integrin activation
- (2008) Asoka Banno et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The urokinase receptor and integrins in cancer progression
- (2008) C.-H. Tang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Interleukin-1β Causes Acute Lung Injury via αvβ5 and αvβ6 Integrin–Dependent Mechanisms
- (2008) Michael T. Ganter et al. CIRCULATION RESEARCH
- Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy
- (2008) Susan M. Dallabrida et al. FASEB JOURNAL
- Intravitreal bevacizumab in active progressive proliferative diabetic retinopathy
- (2008) Siamak Moradian et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling
- (2008) Seiji Mori et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments
- (2008) Patrick T. Caswell et al. JOURNAL OF CELL BIOLOGY
- Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema
- (2008) John Doukas et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Review of the activation of TGF- in immunity
- (2008) A. W. Taylor JOURNAL OF LEUKOCYTE BIOLOGY
- Characterization of the Vitreous Proteome in Diabetes without Diabetic Retinopathy and Diabetes with Proliferative Diabetic Retinopathy
- (2008) Ben-Bo Gao et al. JOURNAL OF PROTEOME RESEARCH
- The CXC-Chemokine CXCL4 Interacts with Integrins Implicated in Angiogenesis
- (2008) Sallouha Aidoudi et al. PLoS One
- Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis
- (2007) Khalid Puthawala et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation
- (2007) Gerald S. Horan et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started