Design, synthesis, anticancer evaluation and molecular docking studies of chalcone linked pyrido[4,3-b]pyrazin-5(6H)-one derivatives

Synthesis, anticancer evaluation and molecular docking studies of 2,5-bis(indolyl)-1,3,4-oxadiazoles, Nortopsentin analogues

(2020) Reddymasu Sreenivasulu et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, antiproliferative and apoptosis induction potential activities of novel bis(indolyl)hydrazide-hydrazone derivatives

(2019) Reddymasu Sreenivasulu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, Synthesis, and Anticancer Activity of Amide Derivatives of Structurally Modified Combretastatin-A4

(2019) V. Ragha Suma et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Synthesis and Anticancer Activity of Amide Derivatives of 1,2-Isoxazole Combined 1,2,4-Thiadiazole

(2019) S. Shahinshavali et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Design, Synthesis, and Biological Evaluation of Novel 2-(4-Arylsubstituted-1H,2,3-triazol-1-yl)-N-{4-[2-(thiazol-2-yl)benzo[d]thiazol-6-yl]phenyl}acetamide Derivatives as Potent Anticancer Agents

(2019) Y. J. Pragathi et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Design, Synthesis, and Anticancer Activity of 1,2,3-Triazole Linked 1,2-Isoxazole-imidazo[4,5-b]pyridine Derivatives

(2019) I. S. Murthy et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Design, Synthesis, and Anticancer Evaluation of 2-{3-{4-[(5-Aryl-1,2,4-oxadiazol-3-yl)methoxy]phenyl}isoxazol-5-yl}-N-(3,4,5-trimethylphenyl)thiazol-4-amine Derivatives

(2019) T. Yakantham et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Design, Synthesis, and Evaluation of Isoxazole-Thiadiazole Linked Carbazole Hybrids as Anticancer Agents

(2019) B. V. Durga Rao et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Targeting ATR as Cancer Therapy: A new era for synthetic lethality and synergistic combinations?

(2019) Alice Bradbury et al.   PHARMACOLOGY & THERAPEUTICS

Synthesis and Antitumor Evaluation of Novel 5-Bromo Indole-Aryl Keto Hydrazide-Hydrazone Analogues

(2018) Durgesh Rudavath et al.   ASIAN JOURNAL OF CHEMISTRY

Extension of antiaromatic norcorrole by cycloaddition

(2018) Xinliang Fu et al.   CHEMICAL COMMUNICATIONS

Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents

(2018) Fedora Grande et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Biological Evaluation and Docking studies of 1,3,4-Oxadiazole Fused Benzothiazole Derivatives for Anticancer Drugs

(2018) Madala Subramanyam et al.   Letters in Drug Design & Discovery

Novel 1,3,4-Oxadiazole Fused Thiadiazole Derivatives: Synthesis and study of Anticancer Activities

(2018) Zanjam Spandana et al.   Letters in Drug Design & Discovery

Design, synthesis and anticancer evaluation of Carbazole Fused aminopyrimidine Derivatives

(2018) Zanjam Spandana et al.   LETTERS IN ORGANIC CHEMISTRY

Rationally Designed PI3Kα Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors

(2017) Yipin Lu et al.   JOURNAL OF MOLECULAR BIOLOGY

The essential kinase ATR: ensuring faithful duplication of a challenging genome

(2017) Joshua C. Saldivar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Synthesis of chalcone incorporated quinazoline derivatives as anticancer agents

(2017) Sapavat Madhavi et al.   SAUDI PHARMACEUTICAL JOURNAL

Synthesis, Biological Evaluation and Molecular Docking Studies of Pyridine Incorporated Chalcone Derivatives as Anticancer Agents

(2016) Sapavat Madhavi et al.   LETTERS IN ORGANIC CHEMISTRY

Synthesis and biological evaluation of oxadiazole incorporated ellipticine derivatives as anticancer agents

(2016) Sapavat Madhavi et al.   MONATSHEFTE FUR CHEMIE

Synthesis, antitumor evaluation, and molecular docking studies of indole–indazolyl hydrazide–hydrazone derivatives

(2016) Reddymasu Sreenivasulu et al.   MONATSHEFTE FUR CHEMIE

Synthesis and biological evaluation of benzoxazole fused combretastatin derivatives as anticancer agents

(2016) N. Bramhananda Reddy et al.   MONATSHEFTE FUR CHEMIE

Synthesis and biological evaluation of benzimidazole fused ellipticine derivatives as anticancer agents

(2016) N. Bramhananda Reddy et al.   MONATSHEFTE FUR CHEMIE

Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents

(2015) Pearly Shuyi Ng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, cytotoxic activity and docking studies of new 4-aza-podophyllotoxin derivatives

(2015) Islavathu Hatti et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis and biological evaluation of 1,3,4-oxadiazole-linked bisindole derivatives as anticancer agents

(2015) Islavathu Hatti et al.   MONATSHEFTE FUR CHEMIE

Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety

(2014) Tamer Nasr et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Advances in Chalcones with Anticancer Activities

(2014) Chandrabose Karthikeyan et al.   Recent Patents on Anti-Cancer Drug Discovery

Synthesis and evaluation of novel 2-pyridone derivatives as inhibitors of phosphodiesterase3 (PDE3): A target for heart failure and platelet aggregation

(2012) Mettu Ravinder et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation

(2011) K. Liaras et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Solid-phase synthesis of 2′-hydroxychalcones. Effects on cell growth inhibition, cell cycle and apoptosis of human tumor cell lines

(2011) Marta Perro Neves et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38α Mitogen-Activated Protein Kinase⊥⊥ Atomic coordinates and structure factors for crystal structure of compound3dwith p38α can be accessed using PDB code 3LHJ.

(2010) Liping H. Pettus et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Pyridazinopyridinones as Potent and Selective p38 Mitogen-Activated Protein Kinase Inhibitors

(2010) Bin Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of a Practical Synthesis of a Pyrazolopyridinone-Based p38 MAP Kinase Inhibitor

(2010) Robert R. Milburn et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Design, Synthesis, and Antihepatitis B Virus Activities of Novel 2-Pyridone Derivatives

(2009) Zhiliang Lv et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antifungal activity of chalcones: A mechanistic study using various yeast strains

(2008) K.L. Lahtchev et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY