The dark side of the gut: Virome–host interactions in intestinal homeostasis and disease

Enteric Virome and Carcinogenesis in the Gut

(2020) Cade Emlet et al.   DIGESTIVE DISEASES AND SCIENCES

Hepatitis E virus finds its path through the gut

(2020) Noémie Oechslin et al.   GUT

Phage diversity, genomics and phylogeny

(2020) Moïra B. Dion et al.   NATURE REVIEWS MICROBIOLOGY

NLRP6 inflammasome

(2020) Runzhi Li et al.   MOLECULAR ASPECTS OF MEDICINE

The stepwise assembly of the neonatal virome is modulated by breastfeeding

(2020) Guanxiang Liang et al.   NATURE

SARS-CoV-2 productively infects human gut enterocytes

(2020) Mart M. Lamers et al.   SCIENCE

Human norovirus targets enteroendocrine epithelial cells in the small intestine

(2020) Kim Y. Green et al.   Nature Communications

5 challenges in understanding the role of the virome in health and disease

(2020) David Wang   PLoS Pathogens

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes

(2020) Ruochen Zang et al.   Science Immunology

Challenges of Studying the Human Virome – Relevant Emerging Technologies

(2020) Mohammadali Khan Mirzaei et al.   TRENDS IN MICROBIOLOGY

Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract

(2020) Jaewon J. Lee et al.   Genes

The Gut Virome Database Reveals Age-Dependent Patterns of Virome Diversity in the Human Gut

(2020) Ann C. Gregory et al.   Cell Host & Microbe

Follow-up Study of Long-time Positive RT-PCR in Stool Specimens From Asymptomatic Children Infected With SARS-CoV-2

(2020) Jun Xie et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Rotavirus VP6 as a potential vaccine candidate

(2019) Atefeh Afchangi et al.   REVIEWS IN MEDICAL VIROLOGY

Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection

(2019) Johanna M. Sweere et al.   SCIENCE

Differential Regulation of Type I and Type III Interferon Signaling

(2019) Megan L. Stanifer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis

(2019) Lasha Gogokhia et al.   Cell Host & Microbe

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

(2019) Sanghyun Lee et al.   Cell Host & Microbe

Shared and Distinct Functions of Type I and Type III Interferons

(2019) Helen M. Lazear et al.   IMMUNITY

Analysis of Spounaviruses as a Case Study for the Overdue Reclassification of Tailed Phages

(2019) Jakub Barylski et al.   SYSTEMATIC BIOLOGY

Advantages and Limitations of Bacteriophages for the Treatment of Bacterial Infections

(2019) Nicola Principi et al.   Frontiers in Pharmacology

Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ

(2019) Harshad Ingle et al.   Nature Microbiology

Dynamic Modulation of the Gut Microbiota and Metabolome by Bacteriophages in a Mouse Model

(2019) Bryan B. Hsu et al.   Cell Host & Microbe

Human Virome and Disease: High-Throughput Sequencing for Virus Discovery, Identification of Phage-Bacteria Dysbiosis and Development of Therapeutic Approaches with Emphasis on the Human Gut

(2019) Tasha M. Santiago-Rodriguez et al.   Viruses-Basel

Phages and Human Health: More Than Idle Hitchhikers

(2019) Lawrence et al.   Viruses-Basel

Bacteriophages benefit from generalized transduction

(2019) Alfred Fillol-Salom et al.   PLoS Pathogens

Composition of the Intestinal Microbiota Determines the Outcome of Virus-Triggered Colitis in Mice

(2019) Silvia Bolsega et al.   Frontiers in Immunology

IFN-I and IL-22 mediate protective effects of intestinal viral infection

(2019) Jessica A Neil et al.   Nature Microbiology

Bacteriophages: Uncharacterized and Dynamic Regulators of the Immune System

(2019) Anshul Sinha et al.   MEDIATORS OF INFLAMMATION

Interactions between noroviruses, the host, and the microbiota

(2019) Forrest C Walker et al.   Current Opinion in Virology

Enteric viruses exploit the microbiota to promote infection

(2019) Christopher M Robinson   Current Opinion in Virology

Studying the gut virome in the metagenomic era: challenges and perspectives

(2019) Sanzhima Garmaeva et al.   BMC BIOLOGY

The Human Gut Virome Is Highly Diverse, Stable, and Individual Specific

(2019) Andrey N. Shkoporov et al.   Cell Host & Microbe

The TLR9 agonist cobitolimod induces IL10 producing wound healing macrophages and regulatory T cells in ulcerative colitis

(2019) Heike Schmitt et al.   Journal of Crohns & Colitis

Generation of Norovirus-Specific T Cells From Human Donors With Extensive Cross-Reactivity to Variant Sequences: Implications for Immunotherapy

(2019) Ryo Hanajiri et al.   JOURNAL OF INFECTIOUS DISEASES

Commensal viruses maintain intestinal intraepithelial lymphocytes via noncanonical RIG-I signaling

(2019) Lei Liu et al.   NATURE IMMUNOLOGY

Viruses RIG up intestinal immunity

(2019) Sanghyun Lee et al.   NATURE IMMUNOLOGY

Bacteriophage Adherence to Mucus Mediates Preventive Protection against Pathogenic Bacteria

(2019) Gabriel M. F. Almeida et al.   mBio

Astrovirus replication in human intestinal enteroids reveals multi-cellular tropism and an intricate host innate immune landscape

(2019) Abimbola O. Kolawole et al.   PLoS Pathogens

Norovirus Changes Susceptibility to Type 1 Diabetes by Altering Intestinal Microbiota and Immune Cell Functions

(2019) James A. Pearson et al.   Frontiers in Immunology

Induction of Phage-Specific Antibodies by Two Therapeutic Staphylococcal Bacteriophages Administered per os

(2019) Joanna Majewska et al.   Frontiers in Immunology

The intestinal regionalization of acute norovirus infection is regulated by the microbiota via bile acid-mediated priming of type III interferon

(2019) Katrina R. Grau et al.   Nature Microbiology

Norovirus, astrovirus, and sapovirus among immunocompromised patients at a tertiary care research hospital

(2018) Shelby Daniel-Wayman et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Clinical efficacy of the Toll-like receptor 9 agonist cobitolimod using patient-reported-outcomes defined clinical endpoints in patients with ulcerative colitis

(2018) Raja Atreya et al.   DIGESTIVE AND LIVER DISEASE

Assessment of the gorilla gut virome in association with natural simian immunodeficiency virus infection

(2018) Mirela D’arc et al.   Retrovirology

Tropism for tuft cells determines immune promotion of norovirus pathogenesis

(2018) Craig B. Wilen et al.   SCIENCE

Extensive conservation of prokaryotic ribosomal binding sites in known and novel picobirnaviruses

(2018) Siddharth R. Krishnamurthy et al.   VIROLOGY

Distinct Effects of Type I and III Interferons on Enteric Viruses

(2018) Harshad Ingle et al.   Viruses-Basel

Enteric Virome Sensing—Its Role in Intestinal Homeostasis and Immunity

(2018) Rebecca Metzger et al.   Viruses-Basel

C-Type Lectin Receptors in Antiviral Immunity and Viral Escape

(2018) Marta Bermejo-Jambrina et al.   Frontiers in Immunology

Phages infecting Faecalibacterium prausnitzii belong to novel viral genera that help to decipher intestinal viromes

(2018) Jeffrey K. Cornuault et al.   Microbiome

The Intestinal Virome and Immunity

(2018) Jessica A. Neil et al.   JOURNAL OF IMMUNOLOGY

HOIL1 is essential for the induction of type I and III interferons by MDA5 and regulates persistent murine norovirus infection

(2018) Donna A. MacDuff et al.   JOURNAL OF VIROLOGY

RNA Phage Biology in a Metagenomic Era

(2018) Julie Callanan et al.   Viruses-Basel

Biology and Taxonomy of crAss-like Bacteriophages, the Most Abundant Virus in the Human Gut

(2018) Emma Guerin et al.   Cell Host & Microbe

ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis

(2018) Andrey N. Shkoporov et al.   Nature Communications

Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells

(2018) Siyuan Ding et al.   eLife

Corrigendum: Staphylococcus aureus Bacteriophage Suppresses LPS-Induced Inflammation in MAC-T Bovine Mammary Epithelial Cells

(2018) Lili Zhang et al.   Frontiers in Microbiology

Exploring the contribution of bacteriophages to antibiotic resistance

(2017) Itziar Lekunberri et al.   ENVIRONMENTAL POLLUTION

Gut microbiota functions: metabolism of nutrients and other food components

(2017) Ian Rowland et al.   EUROPEAN JOURNAL OF NUTRITION

Phages and immunomodulation

(2017) Andrzej Górski et al.   Future Microbiology

Differentiation and Protective Capacity of Virus-Specific CD8 + T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche

(2017) Vesselin T. Tomov et al.   IMMUNITY

Lysogeny in nature: mechanisms, impact and ecology of temperate phages

(2017) Cristina Howard-Varona et al.   ISME Journal

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

(2017) Yu Matsuzawa-Ishimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus

(2017) Megan T. Baldridge et al.   JOURNAL OF VIROLOGY

Pseudomonas phage inhibition of Candida albicans

(2017) Hasan Nazik et al.   MICROBIOLOGY-SGM

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

(2017) Shu Zhu et al.   NATURE

The eukaryotic gut virome in hematopoietic stem cell transplantation: new clues in enteric graft-versus-host disease

(2017) Jérôme Legoff et al.   NATURE MEDICINE

Ménage à trois in the human gut: interactions between host, bacteria and phages

(2017) Mohammadali Khan Mirzaei et al.   NATURE REVIEWS MICROBIOLOGY

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

(2017) Guoyan Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Origins and challenges of viral dark matter

(2017) Siddharth R. Krishnamurthy et al.   VIRUS RESEARCH

The Human Gut Phage Community and Its Implications for Health and Disease

(2017) Pilar Manrique et al.   Viruses-Basel

Shigatoxin encoding Bacteriophage ϕ24B modulates bacterial metabolism to raise antimicrobial tolerance

(2017) G. S. Holt et al.   Scientific Reports

The Peyer’s Patch Mononuclear Phagocyte System at Steady State and during Infection

(2017) Clément Da Silva et al.   Frontiers in Immunology

The major targets of acute norovirus infection are immune cells in the gut-associated lymphoid tissue

(2017) Katrina R. Grau et al.   Nature Microbiology

Discovery of an expansive bacteriophage family that includes the most abundant viruses from the human gut

(2017) Natalya Yutin et al.   Nature Microbiology

Pro- and anti-inflammatory responses of peripheral blood mononuclear cells induced by Staphylococcus aureus and Pseudomonas aeruginosa phages

(2017) Jonas D. Van Belleghem et al.   Scientific Reports

SIV Infection-Mediated Changes in Gastrointestinal Bacterial Microbiome and Virome Are Associated with Immunodeficiency and Prevented by Vaccination

(2016) Scott A. Handley et al.   Cell Host & Microbe

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

(2016) Cynthia L. Monaco et al.   Cell Host & Microbe

Norovirus in symptomatic and asymptomatic individuals: cytokines and viral shedding

(2016) K. L. Newman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

HIV-associated changes in the enteric microbial community

(2016) David B. Gootenberg et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Innate immune evasion strategies of DNA and RNA viruses

(2016) Dia C Beachboard et al.   CURRENT OPINION IN MICROBIOLOGY

Enteric Viruses Ameliorate Gut Inflammation via Toll-like Receptor 3 and Toll-like Receptor 7-Mediated Interferon-β Production

(2016) Jin-Young Yang et al.   IMMUNITY

Gut Virome and Inflammatory Bowel Disease

(2016) Loris R. Lopetuso et al.   INFLAMMATORY BOWEL DISEASES

Viral gastrointestinal infections and norovirus genotypes in a paediatric UK hospital, 2014–2015

(2016) Julianne R. Brown et al.   JOURNAL OF CLINICAL VIROLOGY

Clinical Effects of a Topically Applied Toll-like Receptor 9 Agonist in Active Moderate-to-Severe Ulcerative Colitis

(2016) Raja Atreya et al.   Journal of Crohns & Colitis

Detection of human norovirus in intestinal biopsies from immunocompromised transplant patients

(2016) Umesh C. Karandikar et al.   JOURNAL OF GENERAL VIROLOGY

Pf4 bacteriophage produced by Pseudomonas aeruginosa inhibits Aspergillus fumigatus metabolism via iron sequestration

(2016) Jack C. Penner et al.   MICROBIOLOGY-SGM

The human intestinal B-cell response

(2016) J Spencer et al.   Mucosal Immunology

Alignment-free $d_2^*$ oligonucleotide frequency dissimilarity measure improves prediction of hosts from metagenomically-derived viral sequences

(2016) Nathan A. Ahlgren et al.   NUCLEIC ACIDS RESEARCH

Healthy human gut phageome

(2016) Pilar Manrique et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transkingdom control of viral infection and immunity in the mammalian intestine

(2016) J. K. Pfeiffer et al.   SCIENCE

How colonization by microbiota in early life shapes the immune system

(2016) Thomas Gensollen et al.   SCIENCE

TLR-7 activation enhances IL-22–mediated colonization resistance against vancomycin-resistant enterococcus

(2016) Michael C. Abt et al.   Science Translational Medicine

Human bocavirus: Current knowledge and future challenges

(2016) Marcello Guido et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Viruses Causing Gastroenteritis: The Known, The New and Those Beyond

(2016) Bas Oude Munnink et al.   Viruses-Basel

Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling

(2016) Jessica A. Pane et al.   Scientific Reports

Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

(2016) Timothy J. Nice et al.   PLoS Pathogens

Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding

(2016) Gopal Sapparapu et al.   PLoS Pathogens

Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections

(2016) Jian-Da Lin et al.   PLoS Pathogens

Norovirus-Specific Memory T Cell Responses in Adult Human Donors

(2016) Maria Malm et al.   Frontiers in Microbiology

T4 Phage Tail Adhesin Gp12 Counteracts LPS-Induced Inflammation In Vivo

(2016) Paulina Miernikiewicz et al.   Frontiers in Microbiology

Human anelloviruses: an update of molecular, epidemiological and clinical aspects

(2015) Sonia Spandole et al.   ARCHIVES OF VIROLOGY

Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease

(2015) Jason M. Norman et al.   CELL

Mucosal and Cellular Immune Responses to Norwalk Virus

(2015) Sasirekha Ramani et al.   JOURNAL OF INFECTIOUS DISEASES

Gut Inflammation and Immunity: What Is the Role of the Human Gut Virome?

(2015) Alfredo Focà et al.   MEDIATORS OF INFLAMMATION

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Early life dynamics of the human gut virome and bacterial microbiome in infants

(2015) Efrem S Lim et al.   NATURE MEDICINE

Nlrp6 regulates intestinal antiviral innate immunity

(2015) Penghua Wang et al.   SCIENCE

Silencing the alarms: Innate immune antagonism by rotavirus NSP1 and VP3

(2015) Marco Morelli et al.   VIROLOGY

Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia

(2015) Nagayasu Egawa et al.   Viruses-Basel

Oral Application of T4 Phage Induces Weak Antibody Production in the Gut and in the Blood

(2015) Joanna Majewska et al.   Viruses-Basel

Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

(2015) Mahima Swamy et al.   Nature Communications

Mammalian Host-Versus-Phage immune response determines phage fate in vivo

(2015) Katarzyna Hodyra-Stefaniak et al.   Scientific Reports

The Virome in Mammalian Physiology and Disease

(2014) Herbert W. Virgin   CELL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Norovirus infection in immunocompromised hosts

(2014) K.Y. Green   CLINICAL MICROBIOLOGY AND INFECTION

Norovirus Triggered Microbiota-driven Mucosal Inflammation in Interleukin 10-deficient Mice

(2014) Marijana Basic et al.   INFLAMMATORY BOWEL DISEASES

Immunogenicity Studies of Proteins Forming the T4 Phage Head Surface

(2014) K. D browska et al.   JOURNAL OF VIROLOGY

An enteric virus can replace the beneficial function of commensal bacteria

(2014) Elisabeth Kernbauer et al.   NATURE

Characterization of virus-like particles associated with the human faecal and caecal microbiota

(2014) Lesley Hoyles et al.   RESEARCH IN MICROBIOLOGY

Commensal microbes and interferon-  determine persistence of enteric murine norovirus infection

(2014) M. T. Baldridge et al.   SCIENCE

Interferon-  cures persistent murine norovirus infection in the absence of adaptive immunity

(2014) T. J. Nice et al.   SCIENCE

A highly abundant bacteriophage discovered in the unknown sequences of human faecal metagenomes

(2014) Bas E. Dutilh et al.   Nature Communications

Rotavirus Activates Lymphocytes from Non-Obese Diabetic Mice by Triggering Toll-Like Receptor 7 Signaling and Interferon Production in Plasmacytoid Dendritic Cells

(2014) Jessica A. Pane et al.   PLoS Pathogens

Epidemiology, Phylogeny, and Evolution of Emerging EntericPicobirnavirusesof Animal Origin and Their Relationship to Human Strains

(2014) Yashpal S. Malik et al.   Biomed Research International

Bacteriophages: an underestimated role in human and animal health?

(2014) Marianne De Paepe et al.   Frontiers in Cellular and Infection Microbiology

Decoding Norovirus Infection in Crohnʼs Disease

(2013) Mathias Chamaillard et al.   INFLAMMATORY BOWEL DISEASES

Describing the Silent Human Virome with an Emphasis on Giant Viruses

(2013) Nikolay Popgeorgiev et al.   INTERVIROLOGY

Plasmacytoid dendritic cells promote rotavirus-induced human and murine B cell responses

(2013) Emily M. Deal et al.   JOURNAL OF CLINICAL INVESTIGATION

Persistent Enteric Murine Norovirus Infection Is Associated with Functionally Suboptimal Virus-Specific CD8 T Cell Responses

(2013) V. T. Tomov et al.   JOURNAL OF VIROLOGY

Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome

(2013) Sheetal R. Modi et al.   NATURE

Resident viruses and their interactions with the immune system

(2013) Breck A Duerkop et al.   NATURE IMMUNOLOGY

Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore

(2013) Mohammed S. Aiyegbo et al.   PLoS One

T4 Phage and Its Head Surface Proteins Do Not Stimulate Inflammatory Mediator Production

(2013) Paulina Miernikiewicz et al.   PLoS One

Rapid evolution of the human gut virome

(2013) S. Minot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteriophage adhering to mucus provide a non-host-derived immunity

(2013) J. J. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenic Simian Immunodeficiency Virus Infection Is Associated with Expansion of the Enteric Virome

(2012) Scott A. Handley et al.   CELL

Picornavirus and enterovirus diversity with associated human diseases

(2012) Caroline Tapparel et al.   INFECTION GENETICS AND EVOLUTION

Nearly Constant Shedding of Diverse Enteric Viruses by Two Healthy Infants

(2012) B. Kapusinszky et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Critical Role for Interferon Regulatory Factor 3 (IRF-3) and IRF-7 in Type I Interferon-Mediated Control of Murine Norovirus Replication

(2012) L. B. Thackray et al.   JOURNAL OF VIROLOGY

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Going viral: next-generation sequencing applied to phage populations in the human gut

(2012) Alejandro Reyes et al.   NATURE REVIEWS MICROBIOLOGY

The Inhibitory Receptor PD-1 Regulates IgA Selection and Bacterial Composition in the Gut

(2012) S. Kawamoto et al.   SCIENCE

Multiple virus infection alters rotavirus replication and expression of cytokines and Toll-like receptors in intestinal epithelial cells

(2012) Houping Wang et al.   VIRUS RESEARCH

The human gut virome: Inter-individual variation and dynamic response to diet

(2011) S. Minot et al.   GENOME RESEARCH

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Control of antiviral immunity by pattern recognition and the microbiome

(2011) Iris K. Pang et al.   IMMUNOLOGICAL REVIEWS

Toll-like receptor-7 ligand imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis

(2011) Satheesh K. Sainathan et al.   INFLAMMATORY BOWEL DISEASES

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

The Early Interferon Response to Rotavirus Is Regulated by PKR and Depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3

(2011) A. Sen et al.   JOURNAL OF VIROLOGY

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

(2011) Natalia Shulzhenko et al.   NATURE MEDICINE

Microviridae Goes Temperate: Microvirus-Related Proviruses Reside in the Genomes of Bacteroidetes

(2011) Mart Krupovic et al.   PLoS One

IFN-  determines the intestinal epithelial antiviral host defense

(2011) J. Pott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

RIG-I/MDA5/MAVS Are Required To Signal a Protective IFN Response in Rotavirus-Infected Intestinal Epithelium

(2010) A. H. Broquet et al.   JOURNAL OF IMMUNOLOGY

Pepper Mild Mottle Virus, a Plant Virus Associated with Specific Immune Responses, Fever, Abdominal Pains, and Pruritus in Humans

(2010) Philippe Colson et al.   PLoS One

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

Redefining Chronic Viral Infection

(2009) Herbert W. Virgin et al.   CELL

Low counts of Faecalibacterium prausnitzii in colitis microbiota

(2009) H. Sokol et al.   INFLAMMATORY BOWEL DISEASES

Multiple Diverse Circoviruses Infect Farm Animals and Are Commonly Found in Human and Chimpanzee Feces

(2009) L. Li et al.   JOURNAL OF VIROLOGY

Phage-Mediated Intergeneric Transfer of Toxin Genes

(2009) J. Chen et al.   SCIENCE

Dysbiosis in inflammatory bowel disease: a role for bacteriophages?

(2008) P Lepage et al.   GUT

Antibody Is Critical for the Clearance of Murine Norovirus Infection

(2008) K. A. Chachu et al.   JOURNAL OF VIROLOGY

Immune Mechanisms Responsible for Vaccination against and Clearance of Mucosal and Lymphatic Norovirus Infection

(2008) Karen A. Chachu et al.   PLoS Pathogens

MDA-5 Recognition of a Murine Norovirus

(2008) Stephen A. McCartney et al.   PLoS Pathogens

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens

Bacteriophage preparation inhibition of reactive oxygen species generation by endotoxin-stimulated polymorphonuclear leukocytes

(2007) Ryszard Miedzybrodzki et al.   VIRUS RESEARCH