IFN-I and IL-22 mediate protective effects of intestinal viral infection

Interleukin-22 protects intestinal stem cells against genotoxic stress

(2019) Konrad Gronke et al.   NATURE

Obstructive Lymphangitis Precedes Colitis in Murine Norovirus–Infected Stat1-Deficient Mice

(2018) Audrey Seamons et al.   AMERICAN JOURNAL OF PATHOLOGY

Tropism for tuft cells determines immune promotion of norovirus pathogenesis

(2018) Craig B. Wilen et al.   SCIENCE

The Intestinal Virome and Immunity

(2018) Jessica A. Neil et al.   JOURNAL OF IMMUNOLOGY

HOIL1 is essential for the induction of type I and III interferons by MDA5 and regulates persistent murine norovirus infection

(2018) Donna A. MacDuff et al.   JOURNAL OF VIROLOGY

Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism

(2018) Kairui Mao et al.   NATURE

Autophagy proteins suppress protective type I interferon signalling in response to the murine gut microbiota

(2018) Patricia K. Martin et al.   Nature Microbiology

Persistence of Systemic Murine Norovirus Is Maintained by Inflammatory Recruitment of Susceptible Myeloid Cells

(2018) Jacob A. Van Winkle et al.   Cell Host & Microbe

Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens

(2018) Romain Bouziat et al.   Cell Host & Microbe

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

(2017) Yu Matsuzawa-Ishimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus

(2017) Megan T. Baldridge et al.   JOURNAL OF VIROLOGY

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease

(2017) Romain Bouziat et al.   SCIENCE

Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens

(2017) Yun-Gi Kim et al.   SCIENCE

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine–Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2

(2017) Broc T. McCune et al.   mBio

Enteric Viruses Ameliorate Gut Inflammation via Toll-like Receptor 3 and Toll-like Receptor 7-Mediated Interferon-β Production

(2016) Jin-Young Yang et al.   IMMUNITY

TLR-7 activation enhances IL-22–mediated colonization resistance against vancomycin-resistant enterococcus

(2016) Michael C. Abt et al.   Science Translational Medicine

Type I Interferons Link Viral Infection to Enhanced Epithelial Turnover and Repair

(2015) Lulu Sun et al.   Cell Host & Microbe

The Virome in Host Health and Disease

(2015) Ken Cadwell   IMMUNITY

Regulation of Norovirus Virulence by the VP1 Protruding Domain Correlates with B Cell Infection Efficiency

(2015) Shu Zhu et al.   JOURNAL OF VIROLOGY

Early life dynamics of the human gut virome and bacterial microbiome in infants

(2015) Efrem S Lim et al.   NATURE MEDICINE

Nlrp6 regulates intestinal antiviral innate immunity

(2015) Penghua Wang et al.   SCIENCE

Intestinal macrophages arising from CCR2+ monocytes control pathogen infection by activating innate lymphoid cells

(2015) Sang-Uk Seo et al.   Nature Communications

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration

(2014) Markus Tschurtschenthaler et al.   GUT

Norovirus Triggered Microbiota-driven Mucosal Inflammation in Interleukin 10-deficient Mice

(2014) Marijana Basic et al.   INFLAMMATORY BOWEL DISEASES

An enteric virus can replace the beneficial function of commensal bacteria

(2014) Elisabeth Kernbauer et al.   NATURE

Commensal microbes and interferon-  determine persistence of enteric murine norovirus infection

(2014) M. T. Baldridge et al.   SCIENCE

Interferon-  cures persistent murine norovirus infection in the absence of adaptive immunity

(2014) T. J. Nice et al.   SCIENCE

Enteric bacteria promote human and mouse norovirus infection of B cells

(2014) M. K. Jones et al.   SCIENCE

Persistent Enteric Murine Norovirus Infection Is Associated with Functionally Suboptimal Virus-Specific CD8 T Cell Responses

(2013) V. T. Tomov et al.   JOURNAL OF VIROLOGY

EMPeror: a tool for visualizing high-throughput microbial community data

(2013) Yoshiki Vázquez-Baeza et al.   GigaScience

Associating microbiome composition with environmental covariates using generalized UniFrac distances

(2012) Jun Chen et al.   BIOINFORMATICS

Protruding Domain of Capsid Protein Is Necessary and Sufficient To Determine Murine Norovirus Replication and Pathogenesis In Vivo

(2012) D. W. Strong et al.   JOURNAL OF VIROLOGY

A Single-Amino-Acid Change in Murine Norovirus NS1/2 Is Sufficient for Colonic Tropism and Persistence

(2012) T. J. Nice et al.   JOURNAL OF VIROLOGY

Inherent Structural Disorder and Dimerisation of Murine Norovirus NS1-2 Protein

(2012) Estelle S. Baker et al.   PLoS One

IFN-  determines the intestinal epithelial antiviral host defense

(2011) J. Pott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Prevalence and characteristics of asymptomatic norovirus infection in the community in England

(2010) G. PHILLIPS et al.   EPIDEMIOLOGY AND INFECTION

UniFrac: an effective distance metric for microbial community comparison

(2010) Catherine Lozupone et al.   ISME Journal

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

(2009) Geethanjali Pickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Single Amino Acid Substitution in the Murine Norovirus Capsid Protein Is Sufficient for Attenuation In Vivo

(2008) D. Bailey et al.   JOURNAL OF VIROLOGY

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

MDA-5 Recognition of a Murine Norovirus

(2008) Stephen A. McCartney et al.   PLoS Pathogens