How colonization by microbiota in early life shapes the immune system

Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans

(2016) Ron Sender et al.   CELL

The maternal microbiota drives early postnatal innate immune development

(2016) M. Gomez de Aguero et al.   SCIENCE

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

(2015) Aleksandar D. Kostic et al.   Cell Host & Microbe

Human breast milk: A review on its composition and bioactivity

(2015) Nicholas J. Andreas et al.   EARLY HUMAN DEVELOPMENT

The effect of past antibiotic exposure on diabetes risk

(2015) B. Boursi et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes

(2015) Tiffany C. Scharschmidt et al.   IMMUNITY

Individual intestinal symbionts induce a distinct population of ROR + regulatory T cells

(2015) E. Sefik et al.   SCIENCE

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

(2015) M. J. Schuijs et al.   SCIENCE

Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis

(2015) Peter Zanvit et al.   Nature Communications

Site-specific programming of the host epithelial transcriptome by the gut microbiota

(2015) Felix Sommer et al.   GENOME BIOLOGY

Involvement of the iNKT Cell Pathway Is Associated With Early-Onset Eosinophilic Esophagitis and Response to Allergen Avoidance Therapy

(2014) Willem S Lexmond et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells

(2014) Dingding An et al.   CELL

Infant antibiotic exposure and the development of childhood overweight and central adiposity

(2014) M B Azad et al.   INTERNATIONAL JOURNAL OF OBESITY

Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease

(2014) Sebastian Zeissig et al.   NATURE IMMUNOLOGY

Lung microbiota promotes tolerance to allergens in neonates via PD-L1

(2014) Eva S Gollwitzer et al.   NATURE MEDICINE

Secretory antibodies in breast milk promote long-term intestinal homeostasis by regulating the gut microbiota and host gene expression

(2014) E. W. Rogier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Induction of Antimicrobial REGIII by the Intestinal Microbiota and Bifidobacterium breve NCC2950

(2013) Jane M. M. Natividad et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels

(2013) Julia Cahenzli et al.   Cell Host & Microbe

Association of caesarean delivery with child adiposity from age 6 weeks to 15 years

(2013) J Blustein et al.   INTERNATIONAL JOURNAL OF OBESITY

Intestinal bacteria induce TSLP to promote mutualistic T-cell responses

(2013) I Mosconi et al.   Mucosal Immunology

Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection

(2013) Shokrollah Elahi et al.   NATURE

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

(2013) Anna Cebula et al.   NATURE

Bacterial Diversity in Meconium of Preterm Neonates and Evolution of Their Fecal Microbiota during the First Month of Life

(2013) Laura Moles et al.   PLoS One

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

(2013) J. G. M. Markle et al.   SCIENCE

Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

(2012) Hachung Chung et al.   CELL

Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma

(2012) Shannon L Russell et al.   EMBO REPORTS

Intestinal Microbes Affect Phenotypes and Functions of Invariant Natural Killer T Cells in Mice

(2012) Gerhard Wingender et al.   GASTROENTEROLOGY

Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota

(2012) Stephanie C. Ganal et al.   IMMUNITY

Colonic patch and colonic SILT development are independent and differentially regulated events

(2012) A P Baptista et al.   Mucosal Immunology

Human gut microbiome viewed across age and geography

(2012) Tanya Yatsunenko et al.   NATURE

Antibiotic Exposure and IBD Development Among Children: A Population-Based Cohort Study

(2012) M. P. Kronman et al.   PEDIATRICS

Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

(2012) T. Olszak et al.   SCIENCE

Significance of para-esophageal lymph nodes in food or aeroallergen-induced iNKT cell-mediated experimental eosinophilic esophagitis

(2011) Priya Rajavelu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Establishment of intestinal homeostasis during the neonatal period

(2011) Silvia Stockinger et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cesarean Versus Vaginal Delivery: Long-term Infant Outcomes and the Hygiene Hypothesis

(2011) Josef Neu et al.   CLINICS IN PERINATOLOGY

Identity, regulation andin vivofunction of gut NKp46+RORγt+and NKp46+RORγt−lymphoid cells

(2011) Ana Reynders et al.   EMBO JOURNAL

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

(2011) Markus B. Geuking et al.   IMMUNITY

Control of epithelial cell function by interleukin-22-producing RORγt+ innate lymphoid cells

(2011) Stephanie L. Sanos et al.   IMMUNOLOGY

Invariant NKT cells are required for airway inflammation induced by environmental antigens

(2011) Gerhard Wingender et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peripheral education of the immune system by colonic commensal microbiota

(2011) Stephanie K. Lathrop et al.   NATURE

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

(2011) Shinichiro Sawa et al.   NATURE IMMUNOLOGY

Unravelling the effects of the environment and host genotype on the gut microbiome

(2011) Aymé Spor et al.   NATURE REVIEWS MICROBIOLOGY

Antibiotic Exposure by 6 Months and Asthma and Allergy at 6 Years: Findings in a Cohort of 1,401 US Children

(2010) K. R. Risnes et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Association Between the Use of Antibiotics in the First Year of Life and Pediatric Inflammatory Bowel Disease

(2010) Souradet Y Shaw et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

miR-146a Mediates Protective Innate Immune Tolerance in the Neonate Intestine

(2010) Cécilia Chassin et al.   Cell Host & Microbe

Antibiotic use in early life and development of allergic diseases: respiratory infection as the explanation

(2010) X.-M. Mai et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

(2010) A. K. Benson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

(2010) L. Dethlefsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Succession of microbial consortia in the developing infant gut microbiome

(2010) J. E. Koenig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

(2010) S. Hapfelmeier et al.   SCIENCE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Reproducible Community Dynamics of the Gastrointestinal Microbiota following Antibiotic Perturbation

(2009) D. A. Antonopoulos et al.   INFECTION AND IMMUNITY

Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells

(2009) Bianca Schaub et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Systematic Review: The Role of Breastfeeding in the Development of Pediatric Inflammatory Bowel Disease

(2009) Andrew R. Barclay et al.   JOURNAL OF PEDIATRICS

Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense

(2008) Naoko Satoh-Takayama et al.   IMMUNITY

Innate immune recognition of the indigenous microbial flora

(2008) S Rakoff-Nahoum et al.   Mucosal Immunology

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells

(2008) Stephanie L Sanos et al.   NATURE IMMUNOLOGY

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing

(2008) Les Dethlefsen et al.   PLOS BIOLOGY

A meta-analysis of the association between Caesarean section and childhood asthma

(2007) S. Thavagnanam et al.   CLINICAL AND EXPERIMENTAL ALLERGY